scholarly journals Dietary Cholesterol Affects Plasma Lipid Levels, the Intravascular Processing of Lipoproteins and Reverse Cholesterol Transport without Increasing the Risk for Heart Disease

Nutrients ◽  
2012 ◽  
Vol 4 (8) ◽  
pp. 1015-1025 ◽  
Author(s):  
Jacqueline Barona ◽  
Maria Luz Fernandez
Keyword(s):  
Heart Disease ◽  
Reverse Cholesterol Transport ◽  
Dietary Cholesterol ◽  
Plasma Lipid ◽  
Cholesterol Transport ◽  
Lipid Levels

Plasma lipid levels during ACS: Association with 20-year mortality: The ABC-5 Study on Heart Disease

2019 ◽  
Vol 27 (19) ◽  
pp. 2176-2179 ◽  
Author(s):  
Giuseppe Berton ◽  
Rocco Cordiano ◽  
Heba T Mahmoud ◽  
Francesco Bagato ◽  
Fiorella Cavuto ◽  
...  
Keyword(s):  
Heart Disease ◽  
Plasma Lipid ◽  
Lipid Levels

Abstract 186: Reduction Of High density lipoprotein Cholesterol After Successfull Dietary Intervention Is Not Accompanied By A Change In Reverse Cholesterol Transport

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Rudolf Poledne
Keyword(s):  
Reverse Cholesterol Transport ◽  
Ldl Cholesterol ◽  
Dietary Cholesterol ◽  
Saturated Fat ◽  
Hdl Cholesterol ◽  
Cholesterol Concentration ◽  
Cholesterol Transport ◽  
High Cholesterol ◽  
Unsaturated Fat ◽  
Low Cholesterol

Substitution of dietary saturated fat by unsaturated fat and the reduction of dietary cholesterol intake leads to a decrease of LDL cholesterol concentration accompanied usually by a decrease of HDL cholesterol. Method: 18 young male volunteers were fed for 4 weeks either a high cholesterol saturated fat diet or low cholesterol and unsaturated fat diet in crossover design. At the end of both experimental periods, the lipoprotein concentration was determined. In addition, the reverse cholesterol transport from 14 C cholesterol labeled macrophages in tissue cultures was analyzed. Reverse cholesterol transport was calculated as the percentage of radioactivity released from pre-labeled cells to incubation media with serum of each individuals. Results: Highly significant decrease of LDL cholesterol after the unsaturated fat diet was accompanied by a significant decrease of the HDL cholesterol from 1.25 mmol/l to 1.05 mmol/l. Reverse cholesterol transport did not significantly change when the data of high cholesterol saturated fat diet (9.97 ± 1.45) and low cholesterol unsaturated fat diet (9.53 ± 1.41) were compared. There was no correlation between data of the decrease of HDL cholesterol concentration and change in reverse cholesterol transport. Conclusion: We conclude that dietary treatment by hypocholesterolemic diet accompanied by a reduction of HDL cholesterol does not lead to the decrease in reverse cholesterol transport.

Influence of CETP gene variation on plasma lipid levels and coronary heart disease: a survey in Taiwan

2001 ◽  
Vol 159 (2) ◽  
pp. 451-458 ◽  
Author(s):  
June Hsieh Wu ◽  
Yuan-Teh Lee ◽  
Hsiu-Ching Hsu ◽  
Ling-Ling Hsieh
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Plasma Lipid ◽  
Lipid Levels ◽  
Gene Variation

scholarly journals Beyond Statins: Emerging Evidence for HDL-Increasing Therapies and Diet in Treating Cardiovascular Disease

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Sterling Farrer
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Stress Reduction ◽  
Reverse Cholesterol Transport ◽  
Treatment Options ◽  
The United States ◽  
Exercise Stress ◽  
Cholesterol Transport ◽  
Peripheral Tissues ◽  
Positive Effects

Coronary heart disease continues to be the leading cause of death in the United States. Current attempts to treat atherosclerosis and coronary artery disease often involve pharmaceutical and surgical treatments. While these treatments are successful in managing the pain from coronary heart disease, they do little to prevent or stop it. There are a number of clinical strategies that are currently being researched to treat atherosclerosis through HDL-increasing therapies. These clinical studies have shown positive effects through nutritional intervention, exercise, stress reduction, and tobacco and alcohol cessation. These treatment options are explored in greater detail, including their potential to halt and even reverse atherosclerosis. The results from these recent studies and how they relate to the mechanism of reverse cholesterol transport are also critically examined. Reverse cholesterol transport is a multistep process resulting in the net movement of cholesterol from peripheral tissues back to the liver via the plasma. The mechanism of reverse cholesterol transport is also further explored in this review.

scholarly journals Consistent Effects of Genes Involved in Reverse Cholesterol Transport on Plasma Lipid and Apolipoprotein Levels in CARDIA Participants

2006 ◽  
Vol 26 (8) ◽  
pp. 1828-1836 ◽  
Author(s):  
Kathy L.E. Klos ◽  
Charles F. Sing ◽  
Eric Boerwinkle ◽  
Sara C. Hamon ◽  
Thomas J. Rea ◽  
...  
Keyword(s):  
Reverse Cholesterol Transport ◽  
Plasma Lipid ◽  
Cholesterol Transport
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