scholarly journals Nanoparticles as a Tool in Neuro-Oncology Theranostics

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 948
Author(s):  
Andrea L. Klein ◽  
Grant Nugent ◽  
John Cavendish ◽  
Werner J. Geldenhuys ◽  
Krishnan Sriram ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Photoacoustic Imaging ◽  
Metal Oxide Nanoparticles ◽  
Physicochemical Characteristics ◽  
Fluorescent Imaging ◽  
Current Evidence ◽  
Oxide Nanoparticles ◽  
Imaging Tool ◽  
Imaging Characteristics ◽  
Central Nervous System Malignancy

The rapid growth of nanotechnology and the development of novel nanomaterials with unique physicochemical characteristics provides potential for the utility of nanomaterials in theranostics, including neuroimaging, for identifying neurodegenerative changes or central nervous system malignancy. Here we present a systematic and thorough review of the current evidence pertaining to the imaging characteristics of various nanomaterials, their associated toxicity profiles, and mechanisms for enhancing tropism in an effort to demonstrate the utility of nanoparticles as an imaging tool in neuro-oncology. Particular attention is given to carbon-based and metal oxide nanoparticles and their theranostic utility in MRI, CT, photoacoustic imaging, PET imaging, fluorescent and NIR fluorescent imaging, and SPECT imaging.

scholarly journals Phytosynthetic Fabrication of Lanthanum Ion-Doped Nickel Oxide Nanoparticles Using Sesbania grandiflora Leaf Extract and Their Anti-Microbial Properties

Crystals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 124
Author(s):  
Srihasam Saiganesh ◽  
Thyagarajan Krishnan ◽  
Golla Narasimha ◽  
Hesham S. Almoallim ◽  
Sulaiman Ali Alhari ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Optical Properties ◽  
Rare Earth ◽  
Nickel Oxide ◽  
Photoelectron Spectroscopy ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Nio Nanoparticles ◽  
X Ray ◽  
Sesbania Grandiflora

Over the past few years, the photogenic fabrication of metal oxide nanoparticles has attracted considerable attention, owing to the simple, eco-friendly, and non-toxic procedure. Herein, we fabricated NiO nanoparticles and altered their optical properties by doping with a rare earth element (lanthanum) using Sesbania grandiflora broth for antibacterial applications. The doping of lanthanum with NiO was systematically studied. The optical properties of the prepared nanomaterials were investigated through UV-Vis diffuse reflectance spectra (UV-DRS) analysis, and their structures were studied using X-ray diffraction analysis. The morphological features of the prepared nanomaterials were examined by scanning electron microscopy and transmission electron microscopy, their elemental structure was analyzed by energy-dispersive X-ray spectral analysis, and their oxidation states were analyzed by X-ray photoelectron spectroscopy. Furthermore, the antibacterial action of NiO and La-doped NiO nanoparticles was studied by the zone of inhibition method for Gram-negative and Gram-positive bacterial strains such as Escherichia coli and Bacillus sublitis. It was evident from the obtained results that the optimized compound NiOLa-04 performed better than the other prepared compounds. To the best of our knowledge, this is the first report on the phytosynthetic fabrication of rare-earth ion Lanthanum (La3+)-doped Nickel Oxide (NiO) nanoparticles and their anti-microbial studies.

scholarly journals Yttrium Oxide Nanoparticle Synthesis: An Overview of Methods of Preparation and Biomedical Applications

2021 ◽  
Vol 11 (5) ◽  
pp. 2172
Author(s):  
Govindasamy Rajakumar ◽  
Lebao Mao ◽  
Ting Bao ◽  
Wei Wen ◽  
Shengfu Wang ◽  
...  
Keyword(s):  
Yttrium Oxide ◽  
Metal Oxide Nanoparticles ◽  
Sol Gel ◽  
Antioxidant Properties ◽  
Nanoparticle Synthesis ◽  
Synthetic Methods ◽  
Host Material ◽  
Solid State Reactions ◽  
Oxide Nanoparticles ◽  
Advantages And Disadvantages

Metal oxide nanoparticles demonstrate uniqueness in various technical applications due to their suitable physiochemical properties. In particular, yttrium oxide (Y2O3) nanoparticle is familiar for technical applications because of its higher dielectric constant and thermal stability. It is widely used as a host material for a variety of rare-earth dopants, biological imaging, and photodynamic therapies. Y2O3 has also been used as a polarizer, phosphor, laser host material, and in the optoelectronic fields for cancer therapy, biosensor, and bioimaging. Yttrium oxide nanoparticles have attractive antibacterial and antioxidant properties. This review focuses on the promising applications of Y2O3, its drawbacks, and its modifications. The synthetic methods of nanoparticles, such as sol-gel, emulsion, chemical methods, solid-state reactions, combustion, colloid reaction techniques, and hydrothermal processing, are recapitulated. Herein, we also discuss the advantages and disadvantages of Y2O3 NPs based biosensors that function through various detection modes including colorimetric, electrochemistry, and chemo luminescent regarding the detection of small organic chemicals, metal ions, and biomarkers.

Star fruit extract-mediated green synthesis of metal oxide nanoparticles

2021 ◽  
pp. 1-8
Author(s):  
Sagadevan Suresh ◽  
Selvaraj Vennila ◽  
J. Anita Lett ◽  
Is Fatimah ◽  
Faruq Mohammad ◽  
...  
Keyword(s):  
Metal Oxide ◽  
Green Synthesis ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Fruit Extract ◽  
Star Fruit
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