scholarly journals Fabrication and Characterization of Polycaprolactone/Chitosan—Hydroxyapatite Hybrid Implants for Peripheral Nerve Regeneration

Polymers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 775
Author(s):  
Katarzyna Nawrotek ◽  
Mariusz Mąkiewicz ◽  
Dawid Zawadzki

Major efforts for the advancement of tubular-shaped implant fabrication focused recently on the development of 3D printing methods that can enable the fabrication of complete devices in a single printing process. However, the main limitation of these solutions is the use of non-biocompatible polymers. Therefore, a new technology for obtaining hybrid implants that employ polymer extrusion and electrophoretic deposition is applied. The fabricated structures are made of two layers: polycaprolactone skeleton and chitosan–hydroxyapatite electrodeposit. Both of them can be functionalized by incorporation of mechanical or biological cues that favor ingrowth, guidance, and correct targeting of axons. The electrodeposition process is conducted at different voltages in order to determine the influence of this process on the structural, chemical, and mechanical properties of implants. In addition, changes in mechanical properties of implants during their incubation in phosphate-buffered solution (pH 7.4) at 37 °C up to 28 days are examined. The presented technology, being low-cost and relatively simple, shall find a broad scope of applications in customized nerve tissue engineering.

2015 ◽  
Vol 1105 ◽  
pp. 51-55 ◽  
Author(s):  
K.M. Gupta ◽  
Kishor Kalauni

Bhimal fibres are quite a newer kind of bio-degradable fibres. They have never been heard before in literatures from the view point of their utility as engineering material. These fibres have been utilized for investigation of their properties. Characterization of this fibre is essential to determine its properties for further use as reinforcing fibre in polymeric, bio-degradable and other kinds of matrix. With this objective, the fabrication method and other mechanical properties of Bhimal-reinforced-PVA biocomposite have been discussed. The stress-strain curves and load-deflection characteristics are obtained. The tensile, compressive, flexure and impact strengths have been calculated. The results are shown in tables and graphs. The results obtained are compared with other existing natural fibre biocomposites. From the observations, it has been concluded that the tensile strength of Bhimal-reinforced-PVA biocomposite is higher than other natural fibre composites. Hence these can be used as reinforcement to produce much lighter weight biocomposites.


Vacuum ◽  
2016 ◽  
Vol 128 ◽  
pp. 230-233 ◽  
Author(s):  
Wei Li ◽  
Jia Meng ◽  
Ping Liu ◽  
Haoming Du ◽  
Ke Zhang ◽  
...  

Polymers ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 1549
Author(s):  
Qian Yang ◽  
Xi Wang ◽  
Xin Ding ◽  
Qiao Li

Textile temperature sensors are highly in demanded keep a real-time and accurate track of human body temperature for identification of healthy conditions or clinical diagnosis. Among various materials for textile temperature sensors, temperature-sensitive metal fibers have highest precision. However, those metal fibers are mechanically too weak, and break constantly during the weaving process. To enhance the mechanical strength of the metal fibers, this paper proposes to make wrapped metal fibers using wrapping technology, and characterize the effect of wrapped metal yarns on both mechanical properties and sensing behaviors. The wrapped yarns were woven into fabrics, forming the fabric temperature sensors. Results show that strength and maximum strain of the wrapped yarns are 2.69 and 1.82 times of pure Pt fibers. The response time of fabric temperature sensors using wrapped yarns was observed as 0.78 s and 1.1 s longer compared to that using Pt fibers when front and back sides contacted heat source, respectively. It is recommended that the wrapping method should be implemented for the protection of Pt fibers in fabric temperature sensors.


2016 ◽  
Vol 107 ◽  
pp. 440-449 ◽  
Author(s):  
Cheng-Dong Li ◽  
Muhammad-Umar Saeed ◽  
Ning Pan ◽  
Zhao-Feng Chen ◽  
Teng-Zhou Xu

2020 ◽  
Author(s):  
Susilawati ◽  
Jantiber Siburian ◽  
Yuan Alfinsyah Sihombing ◽  
Bonar Ferdiansyah ◽  
Sri Ningsih Y. Pakpahan

2007 ◽  
Vol 539-543 ◽  
pp. 763-768 ◽  
Author(s):  
M. García de Cortázar ◽  
Javier Goñi ◽  
J. Coleto ◽  
I. Agote ◽  
P. Egizabal ◽  
...  

A new cost effective process to produce discontinuously reinforced (TiB) TMCs has been developed. The article presents general features of the composites, microstructural characteristics and mechanical properties. The production and characterization of two potential commercial applications are also discussed.


2011 ◽  
Vol 418-420 ◽  
pp. 237-241 ◽  
Author(s):  
Shun Xin Shu ◽  
Chao Rong Li

Nanocomposite fibers are one of the most fascinating materials with broad applications. In the present work,nanocomposite fibers were prepared by a low-cost, simple, and “green” process. The nanocomposite of cellulose acetate/TiO2was realized by combining the functional oxide material TiO2with the regenerating electrospun cellulose acetate fibers. The structural features were characterized by scan electron microcopy, transmission electron microscopy and infrared spectrum. The compositing mechanism was proposed. The surface functionalized hydroxyl by the regenerating process plays an important role for the formation of hybrid material.


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