scholarly journals Multifunctional, Robust, and Porous PHBV—GO/MXene Composite Membranes with Good Hydrophilicity, Antibacterial Activity, and Platelet Adsorption Performance

Polymers ◽  
2021 ◽  
Vol 13 (21) ◽  
pp. 3748
Author(s):  
Yuandong Wu ◽  
Weishuang Zheng ◽  
Yinan Xiao ◽  
Beining Du ◽  
Xingru Zhang ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Composite Membranes ◽  
Polymer Materials ◽  
Hydroxyl Groups ◽  
Gram Negative Bacteria ◽  
Coagulation Time ◽  
Biocompatible Polymer ◽  
Adsorption Performance ◽  
High Antibacterial Activity ◽  
Medium Chain Length

The limitations of hydrophilicity, strength, antibacterial activity adsorption performance of the biobased and biocompatible polymer materials, such as polyhydroxyalkanoates (PHAs), significantly restrict their wider applications especially in medical areas. In this paper, a novel composite membrane with high antibacterial activity and platelet adsorption performance was prepared based on graphene oxide (GO), MXene and 3-hydroxybutyrate-co-hydroxyvalerate (PHBV), which are medium-chain-length-copolymers of PHA. The GO/MXene nanosheets can uniformly inset on the surface of PHBV fibre and give the PHBV—GO/MXene composite membranes superior hydrophilicity due to the presence of hydroxyl groups and terminal oxygen on the surface of nanosheets, which further provides the functional site for the free radical polymerization of ester bonds between GO/MXene and PHBV. As a result, the tensile strength, platelet adsorption, and blood coagulation time of the PHBV—GO/MXene composite membranes were remarkably increased compared with those of the pure PHBV membranes. The antibacterial rate of the PHBV—GO/MXene composite membranes against gram-positive and gram-negative bacteria can reach 97% due to the antibacterial nature of MXene. The improved strength, hydrophilicity, antibacterial activity and platelet adsorption performance suggest that PHBV—GO/MXene composite membranes might be ideal candidates for multifunctional materials for haemostatic applications.

A metal–organic gel based on silver salt and 2-amino-5-mercapto-1,3,4-thiadiazole with high antibacterial activity and excellent dye adsorption performance

2016 ◽  
Vol 40 (11) ◽  
pp. 9125-9131 ◽  
Author(s):  
Yong Cheng ◽  
Qichun Feng ◽  
Ming Yin ◽  
Xiaoyan Ren ◽  
Jianzhong Wang ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Water Treatment ◽  
Silver Salt ◽  
Dye Adsorption ◽  
Adsorption Performance ◽  
High Antibacterial Activity ◽  
Treatment Agent ◽  
Metal Organic ◽  
Organic Gel

A novel Ag(i)–AMTD metal–organic gel may serve as a difunctional water treatment agent.

Autoclave-assisted green synthesis of silver nanoparticles using A. fumigatus mycelia extract and the evaluation of their physico-chemical properties and antibacterial activity

2018 ◽  
Vol 7 (3) ◽  
pp. 217-224 ◽  
Author(s):  
Sarah Ghanbari ◽  
Hamideh Vaghari ◽  
Zahra Sayyar ◽  
Mohammad Adibpour ◽  
Hoda Jafarizadeh-Malmiri
Keyword(s):  
Particle Size ◽  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Chemical Properties ◽  
Heating Time ◽  
Gram Negative Bacteria ◽  
Synthesis Conditions ◽  
High Antibacterial Activity ◽  
Physico Chemical ◽  
Ft Ir

Abstract Silver nanoparticles (AgNPs) were synthesized using Aspergillus fumigatus (A. fumigatus) mycelia extract via the hydrothermal method. The main reducing and stabilizing groups and components of A. fumigatus extract, such as amine, hydroxyl, amid, protein, enzymes, and cell saccharide compounds, were identified by Fourier transform infrared (FT-IR). Central composition design was used to plan the experiments, and response surface methodology was applied to evaluate of the effects of independent variables, including the amount of the prepared extract (5–7 ml) and heating time (10–20 min) at 121°C and 1.5 bar), on the particle size of the synthesized AgNPs, as manifested in broad emission peak (λmax). More stable and spherical monodispersed AgNPs, with mean particle size, polydispersity index (PDI) value, and maximum ζ potential value of 23 nm, 0.270, and +35.3 mV, respectively, were obtained at the optimal synthesis conditions using 7 ml of A. fumigatus extract and heating time of 20 min. The synthesized AgNPs indicated high antibacterial activity against both Gram-positive and Gram-negative bacteria.

scholarly journals Quercetin as a Precursor for the Synthesis of Novel Nanoscale Cu (II) Complex as a Catalyst for Alcohol Oxidation with High Antibacterial Activity

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Zahra Moodi ◽  
Ghodsieh Bagherzade ◽  
Janny Peters
Keyword(s):  
Antibacterial Activity ◽  
Schiff Base ◽  
Biological Activities ◽  
Schiff Base Complex ◽  
13C Nmr Spectroscopy ◽  
Inhibition Zone ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative ◽  
High Antibacterial Activity

Quercetin (3,3′,4′,5,7-pentahydroxyflavone) is one of the dietary flavonoids, distributed in medicinal plants, vegetables, and fruits. Quercetin has the ability to bind with several metal ions to increase its biological activities. In the last two decades, quercetin has attracted considerable attention due to the biological and pharmaceutical activities such as antioxidant, antibacterial, and anticancer. In the present study, quercetin and ethanolamine were used for the synthesis Schiff base complex, which was characterized by IR, 1H NMR, and 13C NMR spectroscopy. The Schiff base has been employed as a ligand for the synthesis of novel nanoscale Cu (II) complex. The product was characterized by FT-IR spectroscopy, FESEM, and XRD. Significantly, the product showed remarkable catalytic activity towards the oxidation of primary and secondary alcohols. The antibacterial activity of the final product was assessed against Staphylococcus aureus (Gram‐positive) and Escherichia coli (Gram‐negative) bacteria using an inhibition zone test. The synthesized nanoscale Cu (II) complex exhibited a strong antibacterial activity against both Gram-positive and Gram-negative bacteria.

scholarly journals 5-Bromo-1-(4-chlorobenzyl)-1H-indole-2-carboxamides as new potent antibacterial agents

2018 ◽  
Vol 24 (6) ◽  
pp. 327-332 ◽  
Author(s):  
Yogesh D. Mane ◽  
Smita S. Patil ◽  
Dhanraj O. Biradar ◽  
Bhimrao C. Khade
Keyword(s):  
Escherichia Coli ◽  
Antibacterial Activity ◽  
Antibacterial Agents ◽  
Inhibitory Concentration ◽  
Antibacterial Activities ◽  
Gram Negative Bacteria ◽  
Internal Standards ◽  
Gram Negative ◽  
E Coli ◽  
High Antibacterial Activity

Abstract Ten 5-bromoindole-2-carboxamides were synthesized, characterized and evaluated for antibacterial activity against pathogenic Gram-negative bacteria Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa and Salmonella Typhi using gentamicin and ciprofloxacin as internal standards. Compounds 7a–c, 7g and 7h exhibit high antibacterial activity with a minimum inhibitory concentration (MIC) of 0.35–1.25 μg/mL. Compounds 7a–c exhibit antibacterial activities that are higher than those of the standards against E. coli and P. aeruginosa.

Structure and mode of action of the antimicrobial peptide arenicin

2008 ◽  
Vol 410 (1) ◽  
pp. 113-122 ◽  
Author(s):  
Jörg Andrä ◽  
Igor Jakovkin ◽  
Joachim Grötzinger ◽  
Oliver Hecht ◽  
Anna D. Krasnosdembskaya ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Antimicrobial Peptide ◽  
Lipid Bilayers ◽  
Mode Of Action ◽  
Solution Structure ◽  
Polymyxin B ◽  
Gram Negative Bacteria ◽  
Bacterial Killing ◽  
Gram Negative ◽  
High Antibacterial Activity

The solution structure and the mode of action of arenicin isoform 1, an antimicrobial peptide with a unique 18-residue loop structure, from the lugworm Arenicola marina were elucidated here. Arenicin folds into a two-stranded antiparallel β-sheet. It exhibits high antibacterial activity at 37 and 4 °C against Gram-negative bacteria, including polymyxin B-resistant Proteus mirabilis. Bacterial killing occurs within minutes and is accompanied by membrane permeabilization, membrane detachment and release of cytoplasm. Interaction of arenicin with reconstituted membranes that mimic the lipopolysaccharide-containing outer membrane or the phospholipid-containing plasma membrane of Gram-negative bacteria exhibited no pronounced lipid specificity. Arenicin-induced current fluctuations in planar lipid bilayers correspond to the formation of short-lived heterogeneously structured lesions. Our results strongly suggest that membrane interaction plays a pivotal role in the antibacterial activity of arenicin.

scholarly journals Graphene Oxide-PES-Based Mixed Matrix Membranes for Controllable Antibacterial Activity against Salmonella typhi and Water Treatment

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Haleema Tariq Bhatti ◽  
Nasir M. Ahmad ◽  
Muhammad Bilal Khan Niazi ◽  
Muhammad Azeem Ur Rehman Alvi ◽  
Naveed Ahmad ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Graphene Oxide ◽  
Composite Membranes ◽  
Salmonella Typhi ◽  
Mixed Matrix Membranes ◽  
Inversion Method ◽  
Hydroxyl Groups ◽  
Mixed Matrix ◽  
Good Potential ◽  
Phase Inversion Method

The present work is focused on preparation, characterization, and antibacterial activity evaluation of graphene oxide/polyethersulfone mixed matrix filtration membranes. Graphene oxide (GO) was synthesized via improved Hummer’s method and characterized by XRD, FTIR, and SEM. FT-IR spectra showed the presence of carboxylic acid and hydroxyl groups on GO nanosheets. Different concentrations of the synthesized GO at 0.25, 0.5, and 1.0 wt. % were incorporated in polyethersulfone (PES) matrix via phase inversion method to fabricate GO-PES membranes. Increasing porosity and formation of wider, finger-like channels were observed with increased GO concentrations relative to pristine membranes as evident from scanning electron microscopy (SEM) micrographs of the fabricated membranes. However, membranes prepared with 1 wt. % GO appear to contain aggregation and narrowing of pore morphology. GO-incorporated membranes demonstrated enhanced flux, water-retaining capacities, and wettability as compared to pristine PES membranes. Shake flask and colony counting methods were employed to carry out antibacterial testing of synthesized GO and fabricated GO-PES membranes against Salmonella typhi (S. typhi)—a gram-negative bacteria present in water that is known as causative agent of typhoid. Synthesized GO showed significant reduction up to 70.8% in S. typhi cell count. In the case of fabricated membranes, variable concentrations of GO are observed to significantly influence the percentage viability of S. typhi, with reduction percentages observed at 41, 60, and 69% for 0.25, 0.5, and 1.0 wt. % GO-incorporated membranes relative to 17% in the case of pristine PES membranes. The results indicate a good potential for applying GO/PES composite membranes for water filtration application.

MoS2-TiO2Nanocomposite with Excellent Adsorption Performance and High Antibacterial Activity

2018 ◽  
Vol 3 (1) ◽  
pp. 81-90 ◽  
Author(s):  
Arnab Pal ◽  
Tushar K. Jana ◽  
Tamanna Roy ◽  
Ananya Pradhan ◽  
Ramaprasad Maiti ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Adsorption Performance ◽  
High Antibacterial Activity

In-vitro Antioxidant and Antibacterial Activity of Methanolic Extract of Shorea robusta Gaertn. F. Resin

2016 ◽  
Vol 6 (4) ◽  
pp. 68
Author(s):  
Sushma Vashisht ◽  
Manish Pal Singh ◽  
Viney Chawla
Keyword(s):  
Antibacterial Activity ◽  
Methanolic Extract ◽  
Diffusion Method ◽  
Gram Negative Bacteria ◽  
Disc Diffusion ◽  
Gram Positive ◽  
Gram Negative ◽  
Shorea Robusta ◽  
Dose Dependent ◽  
Resin Extract

The methanolic extract of the resin of Shorea robusta was subjected to investigate its antioxidant and antibacterial properties its utility in free radical mediated diseases including diabetic, cardiovascular, cancer etc. The methanol extract of the resin was tested for antioxidant activity using scavenging activity of DPPH (1,1-diphenyl-2-picrylhydrazil) radical method, reducing power by FeCl3 and antibacterial activity against gram positive and gram negative bacteria using disc diffusion method. The phytochemical screening considered the presence of triterpenoids, tannins and flavoniods. Overall, the plant extract is a source of natural antioxidants which might be helpful in preventing the progress of various oxidative stress mediated diseases including aging. The half inhibition concentration (IC50) of resin extract of Shorea robusta and ascorbic acid were 35.60 µg/ml and 31.91 µg/ml respectively. The resin extract exhibit a significant dose dependent inhibition of DPPH activity. Antibacterial activity was observed against gram positive and gram negative bacteria in dose dependent manner.Key Words: Shorea robusta, antioxidant, antibacterial, Disc-diffusion, DPPH.

Antibacterial activity of magnesium oxide nanoparticles prepared by Calcination method

2019 ◽  
Vol 10 (03) ◽  
Author(s):  
Elaf Ayad Kadhem ◽  
Miaad Hamzah Zghair ◽  
Sarah , Hussam H. Tizkam, Shoeb Alahmad Salih Mahdi ◽  
Hussam H. Tizkam ◽  
Shoeb Alahmad
Keyword(s):  
Antibacterial Activity ◽  
Magnesium Oxide ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
Gram Negative Bacteria ◽  
Gram Positive ◽  
Gram Negative ◽  
Gram Positive Bacteria ◽  
Magnesium Oxide Nanoparticles ◽  
Agar Disc

magnesium oxide nanoparticles (MgO NPs) were prepared by simple wet chemical method using different calcination temperatures. The prepared NPs were characterized by Electrostatic Discharge (ESD), Scanning Electron Microscope (SEM) and X-ray Diffraction (XRD). It demonstrates sharp intensive peak with the increase of crystallinty and increase of the size with varying morphologies with respect to increase of calcination temperature. Antibacterial studies were done on gram negative bacteria (E.coli) and gram positive bacteria (S.aureus) by agar disc diffusion method. The zones of inhibitions were found larger for gram positive bacteria than gram negative bacteria, this mean, antibacterial MgO NPs activity more active on gram positive bacteria than gram negative bacteria because of the structural differences. It was found that antibacterial activity of MgO NPs was found it has directly proportional with their concentration.

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