scholarly journals Studies on the Separation and Purification of the Caulis sinomenii Extract Solution Using Microfiltration and Ultrafiltration

Separations ◽  
2021 ◽  
Vol 8 (10) ◽  
pp. 185
Author(s):  
Xi Wang ◽  
Huimin Feng ◽  
Halimulati Muhetaer ◽  
Zuren Peng ◽  
Ping Qiu ◽  
...  
Keyword(s):  
Sodium Hypochlorite ◽  
Ceramic Membrane ◽  
Pure Water ◽  
High Energy ◽  
Sodium Hypochlorite Solution ◽  
Separation And Purification ◽  
Membrane Pore ◽  
Hypochlorite Solution ◽  
Extract Solution ◽  
Membrane Flux

The separation and purification process of alkaloids faces great challenges of pollution, high energy consumption and low continuity. In this study, the effects of ceramic microfiltration (MF) membrane (membrane pore size of 0.50 μm, 0.20 μm, 0.05 μm) and organic ultrafiltration (UF) membrane (membrane molecular weight cut-off of 10 KDa and 1 KDa) on the separation and purification of Caulis sinomenii extract solution in pilot scale were studied. The cleaning effects of different cleaning methods (pure water, 1% HCl-NaOH, 1% sodium hypochlorite) were investigated. The experimental results indicated that 0.05 μm ceramic membrane and 1 kDa UF membrane have higher sinomenine hydrochloride (SH) permeabilities and total solids (TS) removal rates. The ceramic membrane was circulating cleaned by 1% sodium hypochlorite solution for 1 h; the membrane flux can be restored to more than 90% of the original, the membrane flux of 1 kDa UF membrane can be restored to 99.2% of the original by pure water washing. From the above study, the optimal technic parameters was determined in which 0.05 μm ceramic MF membrane and 1 kDa UF membrane were used to separate and purify the Caulis sinomenii extract solution to remove the invalid ingredients, and the two kinds of membranes were cleaned with 1% sodium hypochlorite solution and pure water, respectively, to keep satisfactory membrane fluxes. The study provided an environment-friendly alternative for the separation and purification of alkaloids in natural products, which has a good prospect for the industrial application.

scholarly journals Safety assessment of an etidronate in a sodium hypochlorite solution: randomized double‐blind trial

2019 ◽  
Vol 52 (9) ◽  
pp. 1274-1282 ◽  
Author(s):  
N. V. Ballal ◽  
P. Gandhi ◽  
P. A. Shenoy ◽  
V. Shenoy Belle ◽  
V. Bhat ◽  
...  
Keyword(s):  
Sodium Hypochlorite ◽  
Safety Assessment ◽  
Sodium Hypochlorite Solution ◽  
Double Blind Trial ◽  
Double Blind ◽  
Hypochlorite Solution ◽  
Blind Trial

Reduction of Microbial Pathogens during Apple Cider Production Using Sodium Hypochlorite, Copper Ion, and Sonication

2004 ◽  
Vol 67 (4) ◽  
pp. 766-771 ◽  
Author(s):  
STEPHANIE L. RODGERS ◽  
ELLIOT T. RYSER
Keyword(s):  
Sodium Hypochlorite ◽  
Copper Ion ◽  
Microbial Pathogens ◽  
Sodium Hypochlorite Solution ◽  
Escherichia Coli O157 ◽  
Hypochlorite Solution ◽  
Apple Cider ◽  
E Coli ◽  
Log Reduction ◽  
Pathogen Reduction

Sodium hypochlorite (100 ppm), copper ion water (1 ppm), and sonication (22 to 44 kHz and 44 to 48 kHz) were assessed individually and in combination for their ability to reduce populations of Escherichia coli O157:H7 and Listeria monocytogenes on apples and in apple cider. Commercial unpasteurized cider was inoculated to contain approximately 106 CFU/ml of either pathogen and then sonicated at 44 to 48 kHz, with aliquots removed at intervals of 30 to 60 s for up to 5 min and plated to determine numbers of survivors. Subsequently, whole apples were inoculated by dipping to contain approximately 106 CFU/g E. coli O157:H7 or L. monocytogenes, held overnight, and then submerged in 1 ppm copper ion water with or without 100 ppm sodium hypochlorite for 3 min with or without sonication at 22 to 44 kHz and examined for survivors. Treated apples were also juiced, with the resulting cider sonicated for 3 min. Populations of both pathogens decreased 1 to 2 log CFU/ml in inoculated cider following 3 min of sonication. Copper ion water alone did not significantly reduce populations of either pathogen on inoculated apples. However, when used in combination with sodium hypochlorite, pathogen levels decreased approximately 2.3 log CFU/g on apples. Sonication of this copper ion–sodium hypochlorite solution at 22 to 44 kHz did not further improve pathogen reduction on apples. Numbers of either pathogen in the juice fraction were approximately 1.2 log CFU/ml lower after being juiced, with sonication (44 to 48 kHz) of the expressed juice decreasing L. monocytogenes and E. coli O157:H7 populations an additional 2 log. Hence, a 5-log reduction was achievable for both pathogens with the use of copper ion water in combination with sodium hypochlorite followed by juicing and sonication at 44 to 48 kHz.

Disinfection and surface changes of gutta‐percha cones after immersion in sodium hypochlorite solution containing surfactant

2019 ◽  
Vol 82 (8) ◽  
pp. 1290-1296
Author(s):  
Filipe C. Vitali ◽  
Lincon H. Nomura ◽  
Débora Delai ◽  
Dilma H. N. Henriques ◽  
Ana M. H. Alves ◽  
...  
Keyword(s):  
Sodium Hypochlorite ◽  
Sodium Hypochlorite Solution ◽  
Hypochlorite Solution ◽  
Gutta Percha ◽  
Surface Changes

Microbiological Assay of Low Chlortetracycline Concentrations in Animal Feeds

1965 ◽  
Vol 48 (2) ◽  
pp. 271-277
Author(s):  
Anthony Abbey ◽  
David B Hewel
Keyword(s):  
Sodium Hypochlorite ◽  
Animal Feed ◽  
Microbiological Assay ◽  
Sodium Hypochlorite Solution ◽  
Hypochlorite Solution ◽  
Animal Feeds ◽  
Low Levels

Abstract Satisfactory microbiological values were obtained for animal feeds containing low levels of cblortetracycline (CTC), 5.0–40g CTC/ton. Results were comparable when calculated against both compensating CTC standard curves prepared from blank feed extracts and laboratory-inactivated CTC feed extracts. The inactivation of CTC in animal feed extracts by 5.25% sodium hypochlorite solution and heat was investigated, and it appeared to offer a convenient alternative for preparing compensating CTC standard curves.

Sign in / Sign up

Export Citation Format

Share Document