scholarly journals Lung Involvement Found on Chest CT Scan in a Pre-Symptomatic Person with SARS-CoV-2 Infection: A Case Report

2020 ◽  
Vol 5 (2) ◽  
pp. 56 ◽  
Author(s):  
Ali Asadollahi-Amin ◽  
Mehrdad Hasibi ◽  
Fatemeh Ghadimi ◽  
Hosnieh Rezaei ◽  
SeyedAhmad SeyedAlinaghi

The novel coronavirus SARS-CoV-2 infection is spreading worldwide, and there are many reports of acute respiratory distress syndrome caused by this infection. However, asymptomatic lung involvement has not been reported. We hereby present the case of a 44-year-old health-care worker, who was found to be infected with the SARS-CoV-2 virus after a CT-scan performed for an unrelated condition revealed a lesion in the lung field compatible with COVID-19 infection. His condition deteriorated initially, but eventually improved with supportive treatment and the compassionate use of antivirals and antimalarials and is now in a stable condition.

2020 ◽  
Vol 54 (4s) ◽  
pp. 97-99
Author(s):  
Benjamin D. Sarkodie ◽  
Yaw B. Mensah

Computed Tomography (CT) scan of the chest plays an important role in the diagnosis and management of Coronavirus disease 2019 (COVID-19), the disease caused by the novel coronavirus SARS-CoV-2. COVID-19 pneumoniashows typical CT Scan features which can aid diagnoses and therefore help in the early detection and isolation of infected patients. CT scanners are readily available in many parts of Ghana. It is able to show findings typical for COVID-19 infection of the chest, even in instances where Reverse Transcription Polymerase Chain Reaction (RTPCR) misses the diagnosis. Little is known about the diagnostic potential of chest CT scan and COVID-19 among physicians even though CT scan offers a high diagnostic accuracy.


2021 ◽  
Vol 29 (3) ◽  
Author(s):  
Syahril Ramadhan Saufi ◽  
Muhd Danial Abu Hasan ◽  
Zair Asrar Ahmad ◽  
Mohd Salman Leong ◽  
Lim Meng Hee

The novel Coronavirus 2019 (COVID-19) has spread rapidly and has become a pandemic around the world. So far, about 44 million cases have been registered, causing more than one million deaths worldwide. COVID-19 has had a devastating impact on every nation, particularly the economic sector. To identify the infected human being and prevent the virus from spreading further, easy, and precise screening is required. COVID-19 can be potentially detected by using Chest X-ray and computed tomography (CT) images, as these images contain essential information of lung infection. This radiology image is usually examined by the expert to detect the presence of COVID-19 symptom. In this study, the improved stacked sparse autoencoder is used to examine the radiology images. According to the result, the proposed deep learning model was able to achieve a classification accuracy of 96.6% and 83.0% for chest X-ray and chest CT-scan images, respectively.


2008 ◽  
Vol 108 (5) ◽  
pp. 1014-1017 ◽  
Author(s):  
In Bok Chang ◽  
Byung Moon Cho ◽  
Se Hyuck Park ◽  
Dae Young Yoon ◽  
Sae Moon Oh

✓The authors report on a case of a metastatic choriocarcinoma that mimicked systemic necrotizing vasculitis on a cerebral angiogram. A 35-year-old woman presented with right hemiplegia and a drowsy mental state. A computed tomography (CT) scan revealed an intracerebral hemorrhage in the left frontal region. A cerebral angiogram showed multiple microaneurysms arising from the bilateral anterior cerebral arteries and middle cerebral arteries, and the renal angiogram showed multiple microaneurysms arising from the left distal renal artery. A chest CT scan revealed multiple metastatic lesions in the left lower lung field. The hematoma and microaneurysms were surgically removed. Choriocarcinoma was diagnosed after histological examination. Despite receiving postoperative chemotherapy, the patient died 1 month after the operation.


Author(s):  
Chiara Vassallo ◽  
Francesca Pupo ◽  
Luca Marri ◽  
Chiara Schiavi ◽  
Francesca Giusti ◽  
...  

Since the novel coronavirus disease 2019 (COVID-19) has declared pandemic, the possibility of recurrence of the disease after recovery has become a debated issue. We report a case of an 84-yearsold male patient who was admitted to our hospital for dyspnea and fever. Lab and clinical workout showed that he had COVID-19. After a full recovery of symptoms and a double negative nasopharyngeal swab of SARS-CoV-2 by RT-PCR assay, he was dismissed from the hospital. One month later, he developed again dyspnea and fever with lung involvement. Surprisingly, nasopharyngeal swab of SARS-CoV-2 was positive. Since he denied contacts with confirmed or suspected cases of COVID-19, he probably experienced a reactivation of a persistent infection. The failed eradication of the virus could depend on both virus’ escape mechanisms and dysfunctional immune response. Further studies are needed to confirm the hypothesis of viral reactivation and to identify signs of an incomplete clearance.


Author(s):  
MN Reshetnikov ◽  
DV Plotkin ◽  
ON Zuban ◽  
EM Bogorodskaya

The double burden of the novel coronavirus infection and tuberculosis (TB) is a global challenge. The aspects of emergency surgical care for patients with COVID-19 and TB coinfection remain understudied. The aim of this study was to assess treatment outcomes in acute surgical patients with COVID-19 and preexisting TB coinfection. In 2020, our Center delivered surgical care to 465 patients with COVID-19 and preexisting TB; a total of 64 emergency surgeries were performed on 36 (5.6%) patients, of whom 16 had HIV. Thirteen patients (36.1%) were diagnosed with pulmonary TB; 23 patients (63.9%) had disseminated TB. Chest CT scans showed >25% lung involvement in 61.9% of the patients with COVID-19 pneumonia, 25–50% lung involvement in 30.6% of the patients, and 50–75% lung involvement in 5.6% of the patients. By performing abdominal CT, we were able to detect abdominal TB complications, including perforated tuberculous ulcers of the intestine, intestinal obstruction and tuberculous peritonitis, as well as tuberculous spondylitis complicated by psoas abscess. Of all surgical interventions, 28.2% were abdominal, 23.2% were thoracic, 15.6% were surgeries for soft tissue infection, and 32.8% were other types of surgery. Postoperative mortality was 22.2%. We conclude that COVID-19 did not contribute significantly to postoperative mortality among acute surgical patients with TB.


2021 ◽  
Vol 20 (2) ◽  
pp. 43-55
Author(s):  
Treefa Salih Hasan ◽  

Background: In the novel COVID outbreak , chest imaging was in the front door for the diagnostic approach to any patient with respiratory symptoms , including chest HRCT & lung ultrasound modalities. Objective: To find the correlation between lung ultrasound and chest high-resolution computed tomography (HRCT) signs in patients suffering from COVID-19 pulmonary involvement. Patients and Methods: This cross-sectional observational study conducted in Arbil / Iraq, from July to November 2020 , enrolled 50 patients who assessed using HRCT and lung ultrasound (LUS),12 areas in the chest examined by ultrasound and corresponding percentage (absent or limited, moderate, extensive, severe & critical grads ) of lung affection on HRCT. Results: Analysis of the obtained data from 50 affected patients done , a highly significant positive relation noted between the findings on ultrasound & the extend of lung involvement by chest HRCT (r factor 0.78, the p-value was <0.001), the sensitivity, specificity, and accuracy of LUS were 90%, 70% ,and 68% respectively. Conclusion: The current study showed that ultrasound and HRCT are parallel in assessing the extent of lung involvement among COVID-19 pneumonia victims, thus making lung ultrasound a relevant substitute for HRCT.


2020 ◽  
Author(s):  
Zeinab Shankayi ◽  
Farideh Bahrami ◽  
Tahereh Mohammadzadeh ◽  
Amineh Ghafari Anvar ◽  
Hosein Amini ◽  
...  

Abstract Objectives There is much evidence showing that most of the mortality and morbidity cases are observed in COVID-19 patients with cardiovascular diseases. Thus, the study on COVID 19 patients with cardiovascular diseases is required for their optimum management. The present study presents a preliminary report on the cardiomegaly of laboratory and CT findings of COVID-19 pneumonia in Iran. A total of 115 Patients with COVID-19 pneumonia hospitalized in (confirmed by CT scan and RT-PCR) Baghiyatallah hospital participated in the present study. Results Thirty-three of these patients (26.8%) had cardiomegaly detected by chest CT scan. Creatinine, Urea and CRP levels of patients significantly increased based on cardiovascular disease detection. In contrast, Sodium levels reduced to below the normal in patients with cardiomegaly. Despite respiratory illness as the first symptom of COVID-19, the role of other diseases such as cardiovascular disease requires further investigation.


Author(s):  
Zahra Ahmadinejad ◽  
Faeze Salahshour ◽  
Omid Dadras ◽  
Hesan Rezaei ◽  
SyyedAhmad Alinaghi

Background: Recently, COVID-19 infection has become a public health concern. On March 12th, 2020, the World Health Organization (WHO) announced it as a global pandemic. Early diagnosis of atypical cases of COVID-19 infection is critical in reducing the transmission and controlling the present pandemic. In the present report, we described a patient with the chief complaints of dyspnea and dry cough referred to the oncology center at Imam Khomeini Hospital, Tehran with the differential diagnosis of lung cancer who was diagnosed and treated for COVID-19 infection in follow up. Case presentation: A 59-year-old patient complained of fever, dry cough, and dyspnea from two weeks ago. The patient had been referred to this center with the differential diagnosis of lung cancer due to the massive pleural effusion in initial chest CT scan. Dyspnea was the patient’s main complaint at the time of admission in this center and the oxygen saturation was 84%. In the new chest CT scan, similar findings were observed. Due to the severe respiratory distress, a chest tube was placed in the chest cavity to remove the pleural effusion fluid on day one. The patient’s felt relieved immediately after the procedure; however, the oxygen saturation did not raise above 85% despite the oxygen therapy. The cytology of pleural fluid was negative for malignant cells. On day 2, the lymphopenia and high level of CRP suggested the COVID-19 infection. Therefore, a control chest CT scan was conducted and the test for COVID-19 was performed. The CT report indicated the clear pattern of COVID-19’s lung involvement in the absence of pleural effusion. Thus, the treatment for COVID-19 was immediately initiated. On day 4, the test reported positive for COVID-19. Conclusion: Currently, it is important to bear in mind the COVID-19 infection in evaluating the patients with respiratory symptoms. This report indicated how misleading the presentation of chest CT scan could be in clinical judgment. Therefore, we recommend ruling out the COVID-19 infection in all the patients with any pattern of lung involvement to avoid missing the potential cases of this vicious infection.


2021 ◽  
Vol 8 ◽  
Author(s):  
Carla Maria Irene Quarato ◽  
Antonio Mirijello ◽  
Michele Maria Maggi ◽  
Cristina Borelli ◽  
Raffaele Russo ◽  
...  

Background: In the current coronavirus disease-2019 (COVID-19) pandemic, lung ultrasound (LUS) has been extensively employed to evaluate lung involvement and proposed as a useful screening tool for early diagnosis in the emergency department (ED), prehospitalization triage, and treatment monitoring of COVID-19 pneumonia. However, the actual effectiveness of LUS in characterizing lung involvement in COVID-19 is still unclear. Our aim was to evaluate LUS diagnostic performance in assessing or ruling out COVID-19 pneumonia when compared with chest CT (gold standard) in a population of SARS-CoV-2-infected patients.Methods: A total of 260 consecutive RT-PCR confirmed SARS-CoV-2-infected patients were included in the study. All the patients underwent both chest CT scan and concurrent LUS at admission, within the first 6–12 h of hospital stay.Results: Chest CT scan was considered positive when showing a “typical” or “indeterminate” pattern for COVID-19, according to the RSNA classification system. Disease prevalence for COVID-19 pneumonia was 90.77%. LUS demonstrated a sensitivity of 56.78% in detecting lung alteration. The concordance rate for the assessment of abnormalities by both methods increased in the case of peripheral distribution and middle-lower lung location of lesions and in cases of more severe lung involvement. A total of nine patients had a “false-positive” LUS examination. Alternative diagnosis included chronic heart disease (six cases), bronchiectasis (two cases), and subpleural emphysema (one case). LUS specificity was 62.50%. Collateral findings indicative of overlapping conditions at chest CT were recorded also in patients with COVID-19 pneumonia and appeared distributed with increasing frequency passing from the group with mild disease (17 cases) to that with severe disease (40 cases).Conclusions: LUS does not seem to be an adequate tool for screening purposes in the ED, due to the risk of missing some lesions and/or to underestimate the actual extent of the disease. Furthermore, the not specificity of LUS implies the possibility to erroneously classify pre-existing or overlapping conditions as COVID-19 pneumonia. It seems more safe to integrate a positive LUS examination with clinical, epidemiological, laboratory, and radiologic findings to suggest a “virosis.” Viral testing confirmation is always required.


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