scholarly journals Convalescent Plasma for Pregnant Women with COVID-19: A Systematic Literature Review

Viruses ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1194
Author(s):  
Massimo Franchini ◽  
Federico Prefumo ◽  
Gianpaolo Grisolia ◽  
Valentino Bergamini ◽  
Claudia Glingani ◽  
...  

 The treatment of COVID-19 is particularly critical in pregnant women, considering the potential teratogenic effects of antiviral agents and the immune-depression related with pregnancy. The aim of this review is to systematically examine the current evidence on the clinical use of convalescent plasma during pregnancy. The electronic databases Medline PubMed Advanced Search Builder, Scopus, Web Of Science and Google Scholar were searched (until 1 January 2021). Inclusion criteria were pregnant women with COVID-19 (or SARS-CoV-2 infection), in whom convalescent plasma (or hyperimmune plasma) was used as treatment. We searched clinical trial registries (censored 5 January 2021) for eligible studies under way. After elimination of duplications, the initial search yielded 79 potentially relevant records, of which 67 were subsequently excluded. The 12 remaining records were case reports involving 12 pregnancies. Six of the mothers were reported to be well, two were reported to have preeclampsia, and in one case each the maternal outcome was described as survival, clinical improvement, discharged with oxygen and rehabilitation. With regard to the neonates, two were declared to be well, four had transient morbidity, two were critically ill and one died; normal ongoing pregnancies, but no post-delivery information, were reported for the remaining three cases. Clinical trials under way or planned to investigate the use of convalescent plasma for COVID-19 during pregnancy are lacking. This is the first systematic review of the literature regarding the treatment of COVID-19 in pregnancy. The published literature data seem to indicate that convalescent plasma administered to pregnant women with severe COVID-19 provides benefits for both the mother and the fetus. The quality of the available studies is, however, very limited since they are all case reports and thus suffer from relevant reporting bias. 

2021 ◽  
pp. 019394592199253
Author(s):  
Anna M. Kutcher ◽  
Virginia T. LeBaron

The purpose of this integrative review of the literature is to synthesize the current evidence and identify gaps in knowledge regarding the effectiveness of acupuncture to treat chemotherapy-induced peripheral neuropathy (CIPN). PubMed, CINAHL, Web of Science, and Cochrane Review databases were searched using inclusion criteria: keywords acupuncture, cancer, and peripheral neuropathy, published in English, between 2009 and 2019. Sixteen articles met the inclusion criteria. The literature indicates that acupuncture is generally well tolerated by patients with cancer, and a majority of patients with CIPN reported decreased pain and increased quality of life after receiving acupuncture treatment. A comprehensive understanding of the ability of acupuncture to treat CIPN is limited by variability of acupuncture techniques and inconsistency in measures of evaluation.


RMD Open ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. e001635
Author(s):  
Emma Swärdh ◽  
Christina Opava ◽  
Nina Brodin

BackgroundPhysical activity (PA) in rheumatoid arthritis (RA) is considered a cornerstone in the treatment. To highlight aspects involved in supporting a positive PA behaviour, it is important to understand the patients’ perceptions of the phenomenon.ObjectiveThe aim of this qualitative meta-synthesis was to explore and synthesise patient perceptions of PA in RA.MethodsA purposeful search was conducted across three online databases (PubMed, CINAHL and Web of Science). The methodological quality of the included studies was appraised, and data were extracted and analysed using an interpretive inductive thematic synthesis.ResultsFifteen studies met the inclusion criteria and were included. PA was identified as an agile lifelong behaviour, with one main theme: The disease as a persistent catalyst for or against PA illustrating how the constant presence of the disease itself underlies the entire process of a life with or without regular PA. Seven subthemes: ‘considering aggravated symptoms’, ‘acknowledging the impact on health’, ‘becoming empowered and taking action’, ‘keeping informed to increase awareness’, ‘creating body awareness’, ‘dealing with social support’ and ‘feeling satisfied with circumstances and achievements’ were interpreted as facilitators and/or challenges.ConclusionThis synthesis has identified PA as an agile lifelong behaviour in which the disease pervades all aspects of an individuals’ perception of PA. Placed in a theoretical context, our findings outline a model for tailoring PA support to the drivers and determinants of a certain individual, which will improve clinical practice for the benefit of both health professionals and patients with RA.


Author(s):  
Ioneide De Oliveira Campos ◽  
Rafael Moraes Reis

A Economia Solidária é uma alternativa para inserção laboral de pessoas com transtornos mentais. Realizou-se uma revisão da literatura, com o propósito de conhecer o que tem sido publicado sobre Economia Solidária, inclusão e Saúde Mental, quais os objetivos e métodos de pesquisa, quem são os profissionais e populações-alvo e quais os resultados obtidos nos estudos. Foram considerados os seguintes critérios para a realização desse estudo: a importância da temática para o contexto da Saúde Mental e a identificação de pesquisas e relatos de experiência que informassem práticas em Saúde Mental e Economia Solidária. A revisão foi realizada nas bases: Web of Science, DOAJ, PubMed, SciElo e LILACS, sem restrições de ano. Os descritores utilizados foram “economia solidária”, “saúde mental” e “inclusão”. Vinte e nove (n=29) artigos foram encontrados e, após a aplicação dos critérios de inclusão, dez foram analisados na íntegra. Trinta e quatro (n=34) profissionais estiveram envolvidos nas pesquisas, sendo a Terapia Ocupacional, Enfermagem e Psicologia, as profissões que apareceram mais frequentemente.  Todos os estudos encontrados eram qualitativos e foram conduzidos no Brasil. A entrevista foi o método mais adotado. Os resultados dos estudos sinalizaram ganhos para aspectos intrínsecos dos usuários no que se refere a autogestão, expressão, empoderamento, e também extrínsecos, como a questão familiar e do trabalho coletivo. A revisão agregou conhecimento que permitem refletir sobre a importância da interdisciplinaridade, do trabalho colaborativo em rede, e sobre a necessidade de documentação das experiências em Economia Solidária no país. AbstractThe Solidarity Economy is an alternative for the labour inclusion of people with mental health. A review of the literature was conducted in order to know what has been published on the issue of Solidarity Economy, Inclusion and Mental Health, what are the objectives and research methods, who are the professionals and populations’ target, and the results identified in the research. We considered the following criteria: the importance of the issue in the mental health context and identification of studies and case reports which informed practice in Mental Health and Solidarity Economy. The search was done at the databases: Web of Science, DOAJ, PubMed, Scielo and LILACS, with no year restrictions. The descriptors used were "solidarity economy", "mental health" and "inclusion". Twenty-nine (n=29) were found and after the inclusion criteria filter, ten articles were analysed. Thirty-four (n=34) professionals were involved in the studies and the most were Occupational Therapy, Nursing and Psychology. All the studies found used qualitative approaches and were conducted in Brazil. The interview was the most adopted method for data collection. The results indicate outcomes for users' intrinsic aspects such as self-management, expression, empowerment, and also extrinsic, such as family and collective work. The review added knowledge to reflect about the interdisciplinary and collaborative network, and also on the documentation of experiences in Solidarity Economy in the country.Keywords: Mental health; Solidarity economy; Public policies; Inclusion; Research.ResumenLa Economía Solidaria es una alternativa para la inserción laboral de personas con trastornos mentales. Se realizó una revisión de la literatura, con el fin de conocer qué se ha publicado sobre Economía Solidaria, inclusión y Salud Mental, cuáles son los objetivos y métodos de investigación, quiénes son los profesionales y las poblaciones objetivo y cuáles son los resultados obtenidos. Se consideraron los siguientes criterios para realizar este estudio: la importancia del tema para el contexto de la salud mental y la identificación de informes de investigación y experiencia que informarían las prácticas con la Salud Mental y la Economía Solidaria. La revisión se realizó en las bases de datos: Web of Science, DOAJ, PubMed, Scielo y LILACS, sin restricciones de año. Los descriptores utilizados fueron "economía solidaria", "salud mental" e "inclusión". Veintinueve (n = 29) artículos fueron encontrados y, después de aplicar los criterios de inclusión, diez fueron analizados en su totalidad. Treinta y cuatro (n = 34) profesionales participaron en las investigaciones, siendo la Terapia Ocupacional, Enfermería y Psicología las profesiones que aparecieron con más frecuencia. Todos los estudios encontrados fueron cualitativos y se realizaron en Brasil. La entrevista fue el método más adoptado. Los resultados de los estudios señalaron ganancias para los aspectos intrínsecos de los usuarios, como la autogestión, la expresión, el empoderamiento y también los aspectos extrínsecos, como el tema del trabajo familiar y colectivo. La revisión agregó conocimiento que nos permite reflexionar sobre la importancia de la interdisciplinariedad, así como el trabajo en red colaborativo, y sobre la necesidad de documentar experiencias en Economía Solidaria en el país.Palabras clave: Salud mental; Economía solidaria; Políticas públicas; Inclusión; Investigación.      


2021 ◽  
Vol 4 (2s) ◽  
pp. 78-85
Author(s):  
Tigor Peniel Simanjuntak ◽  
◽  
Angela Putri Kakerissa ◽  
Grady Ivan Kurniawan

Abstract Objective to evaluate antiviral treatment, duration, and side effects on pregnant women based on gestational age and severity of COVID-19 infection. Method: a systematic review of antiviral treatment, duration, and side effects on pregnant women based on gestational age and severity of COVID-19 infection. Systematic review was conducted following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) Statement. Result 948 papers accessed through Pubmed, Scopus, Science Direct, Cohcrane, and other with keywords “Antiviral”, “Pregnancy” “Pregnant” “Coronavirus” “COVID-19” “SARS-CoV-2”. Duplicate papers were excluded (n=302), topics and abstracts that do not meet the criteria (n=612), and 25 papers that did not meet the inclusion criteria. 9 papers that meet the inclusion criteria (case reports and cohort retrospective case study) discussed 20 pregnant women with COVID-19 infection (16 moderate and severe cases received Remdesivir, 3 moderate and mild cases received Lopinavir-ritonavir combination, and 1 moderate case received Arbidol). Conclusion, remdesivir is an antiviral frequently used in pregnancy on trimester II and III with severe COVID-19 infection with a duration of treatment of 5-10 days. Remdesivir should be monitored because some show side effects of increasing liver function. Key word: Antiviral, Pregnant, COVID-19


Author(s):  
Phuong Hong Le ◽  
Quang Vinh Tran ◽  
Trung Quang Vo

Objective: Systematic reviews of economic analysis are necessary for assessing reports and making a decision. A systematic review of systematic reviews is mean of summarizing the current evidence across specialties of the same or very similar intervention, to provide a synthesis treatment effect. The aim of this study was to explore and to assess the quality of systematic reviews conducted hepatitis economic evaluation.Methods: This study was designed as a systematic review following the AMSTAR guideline through Medline, Cochrane, and Science Direct databases. It was scoped in publication period of 2001 and 2016 in international journals. The quality assessment of the included studies was based on AMSTAR checklist. Two authors did the appreciation independently and all the different results were solved by discussion to give the conclusion.Results: 851 publications found, only 25 studies of those met the inclusion criteria. These studies consisted of 5 studies for vaccination and 20 for non-vaccination. There were only 16% (n=4) based on PRISMA guideline; and twenty-one studies (64%) were not showing about the method of the systematic review or not based on any guideline. Only three articles has published in 2016 with a high standard.Conclusion: According to the results of the appraisal AMSTAR checklist, this review shows clearly the current situation and an urgent need for an increase of quality of hepatitis virus review studies based on health economic evaluation.


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Giuseppe Lippi ◽  
Gianfranco Cervellin ◽  
Camilla Mattiuzzi

Vitamin D deficiency is associated with a number of human disorders, including cardiovascular disease, cancer, diabetes, frailty, and infections. Since an association between vitamin D and migraine has also been recently speculated, we performed an electronic search on Medline, Scopus, and Web of Science using the keywords “migraine” and “vitamin D,” “25OH-D” “cholecalciferol,” “ergocalciferol,” with no language or date restriction. The electronic search allowed identifying seven studies (3 observational, 2 cross-sectional, and 2 case reports). The two case reports, including four women, showed favourable effects of vitamin D supplementation on migraine severity, but these studies were small and not placebo controlled. As regards the three observational studies, vitamin D deficiency was observed in 13.2 to 14.8% of migraine patients, and these rates do not differ from those reported in the general population (i.e., vitamin D deficiency between 22 and 42%). The results of the two cross-sectional studies are even more controversial, since no association was found between vitamin D status and migraine in both trials. In conclusion, the current evidence suggests that the association between migraine and vitamin D lacks reliable scientific support.


2019 ◽  
Vol 28 (6) ◽  
pp. 441-450 ◽  
Author(s):  
Vinciya Pandian ◽  
Sarah Boisen ◽  
Shifali Mathews ◽  
Michael J. Brenner

Objective To synthesize evidence of the safety and effectiveness of phonation in patients with fenestrated tracheostomy tubes. Methods PubMed, CINAHL, Scopus, Cochrane, and Web of Science databases were searched. The research question was, “Are fenestrated tracheostomy tubes a safe and effective option to facilitate early phonation in patients undergoing tracheostomy?” Studies of fenestrated tracheostomy tubes were assessed for risk of bias and quality of evidence. Data were abstracted, cross-checked for accuracy, and synthesized. Results Of the 160 studies identified, 13 met inclusion criteria, including 6 clinical studies (104 patients), 6 case reports (13 patients), and 1 nationwide clinician survey. The primary indications for a tracheostomy were chronic ventilator dependence (83%) and airway protection (17%). Indications for fenestrated tracheostomy included inaudible phonation and poor voice intelligibility. Patients with fenestrated tubes achieved robust voice outcomes. Complications included granulation tissue (6 patients [5%]), malpositioning (1 patient [0.9%]), decreased oxygen saturation (3 patients [2.6%]), increased blood pressure (1 patient [0.9%]), increased peak pressures (2 patients [1.7%]), and air leakage (1 patient [0.9%]); subcutaneous emphysema also occurred frequently. Patient-reported symptoms included shortness of breath (4 patients [3.4%]), anxiety (3 patients [2.6%]), and chest discomfort (1 patient [0.9%]). Conclusions Fenestrated devices afford benefits for speech and decannulation but carry risks of granulation, aberrant airflow, and acclimation challenges. Findings highlight the need for continued innovation, education, and quality improvement around the use of fenestrated devices.


2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Wenjing Fu ◽  
Yan Huang ◽  
Xing Liu ◽  
Jianhua Ren ◽  
Mengqin Zhang

Objectives. The purpose of this study was to evaluate the evidence of art therapy on the psychological outcome, quality of life (QOL), and cancer-related symptoms in women with gynecological cancer. Methods. A systematic literature search was conducted. The randomized controlled trials, quasiexperimental studies, case reports, and qualitative studies were all included. Result. 1,587 articles were retrieved. A total of 9 articles met the inclusion criteria. The existing studies provided initial evidence to suggest that art therapy may benefit gynecological cancer patients with respect to improving psychological outcome and QOL, reducing fatigue related to cancer, and improving subjective overall health condition. However, the quality of the current evidence limits the efficacy of these findings. Conclusion. Research on art therapy of gynecologic cancer patients is insufficient. We cannot draw the conclusion that art therapy benefits gynecological cancer patients in the psychological outcome, QOL, and cancer-related symptoms. More rigorous research is needed.


2019 ◽  
Vol 53 (2) ◽  
Author(s):  
Marie Len A. Camaclang ◽  
Leah Antoinette M. Caro-Chang ◽  
Ma. Lorna F. Frez

Objectives. To assess the efficacy and safety of excimer laser in combination with topical standard therapies for treatment of plaque-type psoriasis in comparison to excimer laser alone, standard topical treatment alone, or placebo. Methods. A literature search using Medline, Cochrane and HERDIN was conducted. Data were analyzed using mean difference at 95% confidence interval, with heterogeneity determined by I2 test. Results. Three articles with total of 130 patients fulfilled the inclusion criteria. Topical treatments studied were vitamin analog (calcipotriol), anthralin (dithranol), and steroid (flumethasone pivalate). A subgroup analysis comparing combination therapy and excimer laser alone showed a greater reduction in pooled PASI score reduction (-2.52; 95% CI: -4.28, -0.77) in the combination group after five to six weeks. There was also a significantly greater reduction in cumulative UVB dose (-3.29; 95% CI: -4.29, -2.30) needed for clearing in the combination group. Pigmentation was the commonly observed adverse event in both groups. Conclusions. Excimer laser, in combination with topical treatment, is more effective than excimer laser alone, with significantly lower cumulative UVB dose, but the quality of current evidence is low. Long-term controlled trials are warranted to increase our confidence in the estimates of these outcomes.


Aquichan ◽  
2020 ◽  
Vol 20 (1) ◽  
pp. 1-13
Author(s):  
Edison Vitório de Souza Júnior ◽  
Cristiane dos Santos Silva ◽  
Poliana Souza Lapa ◽  
Laís Emily Souza Trindade ◽  
Benedito Fernandes da Silva Filho ◽  
...  

Objective: this work sought to inquire on the influence of sexuality on the health of the elderly during dementia. Materials and Methods: this was an integrative review. A careful search was conducted in nine databases; however, only five databases provided articles fulfilling the scope of the study: Medline, Lilacs, BDENF, Scopus, and Web of Science (WoS). The health science descriptors (DeCS) were adopted: “sexualidad”, “demencia” and “anciano”, and the descriptors cataloged in the Medical Subject Headings (MeSH): “sexuality”, “dementia” and “aged”. After applying the inclusion criteria, eight articles were selected to comprise the study sample. Results: the practice of sexuality influences upon the health of the elderly with dementia with some beneficial effects, given that it provides, especially, better perception of quality of life and wellbeing. Nevertheless, it cannot be generalized due to methodological insufficiency evidenced in the studies found to construct this review. Conclusions: due to the limitation of studies addressing the theme and the methodological insufficiency of those included in this review, it is necessary to conduct research that shows in depth the influence of sexuality on this population, given that it can be constituted as another approach for the promotion and protection of health in the elderly with dementia.


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