scholarly journals Ordered Mesoporous Carbons for Adsorption of Paracetamol and Non-Steroidal Anti-Inflammatory Drugs: Ibuprofen and Naproxen from Aqueous Solutions

Water ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 1099 ◽  
Author(s):  
Katarzyna Jedynak ◽  
Beata Szczepanik ◽  
Nina Rędzia ◽  
Piotr Słomkiewicz ◽  
Anna Kolbus ◽  
...  
Keyword(s):  
Activated Carbon ◽  
Contact Time ◽  
Theoretical Calculations ◽  
Isotherm Models ◽  
Mesoporous Carbons ◽  
Ordered Mesoporous Carbons ◽  
Chemical Structures ◽  
Ordered Mesoporous ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

The adsorption of paracetamol and non-steroidal anti-inflammatory drugs (ibuprofen and naproxen) on ordered mesoporous carbons (OMC) and, for comparison, on commercial activated carbon, were investigated in this work. OMC adsorbents were obtained by the soft-templating method and were characterized by low-temperature nitrogen adsorption and scanning electron microscopy (SEM). The effects of contact time and initial concentration of organic adsorbates on the adsorption were studied. The contact time to reach equilibrium for maximum adsorption was 360 min for all the studied adsorbates. The adsorption mechanism was found to fit pseudo-second-order and intra particle-diffusion models. Freundlich, Langmuir and Langmuir-Freundlich isotherm models were used to analyze equilibrium adsorption data. Based on the obtained experimental data, the adsorption isotherm in the applied concentration range for all the studied adsorbates was well represented by the Freundlich-Langmuir model. The adsorption ability of ordered mesoporous carbon materials was much higher for paracetamol and naproxen in comparison to commercial activated carbon. The removal efficiency for ibuprofen was significantly lower than for other studied pharmaceuticals and comparable for all adsorbents. Theoretical calculations made it possible to obtain optimized chemical structures of (S)-naproxen, ibuprofen, and paracetamol molecules. Knowledge of charge distributions of these adsorbate molecules can be helpful to explain why paracetamol and naproxen can react more strongly with the surface of adsorbents with a large numbers of acidic groups compared to ibuprofen facilitating more efficient adsorption of these pharmaceuticals on ordered mesoporous carbons.

scholarly journals Treatment of Wastewater Containing Nonsteroidal Anti-Inflammatory Drugs Using Activated Carbon Material

Materials ◽  
2022 ◽  
Vol 15 (2) ◽  
pp. 559
Author(s):  
Florinela Pirvu ◽  
Cristina Ileana Covaliu-Mierlă ◽  
Iuliana Paun ◽  
Gigel Paraschiv ◽  
Vasile Iancu
Keyword(s):  
Wastewater Treatment ◽  
Activated Carbon ◽  
Ph Value ◽  
Equilibrium Concentration ◽  
Isotherm Models ◽  
Array Detector ◽  
Fast Method ◽  
Initial Concentration ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

This study presents an adsorbent material (activated carbon) used in the treatment of wastewater with the role of removing ibuprofen, acetaminophen, diclofenac and ketoprofen pollutants. The wastewater treatment efficiencies of the activated carbon were systematically investigated using adsorption kinetics. The parameters studied were: pH (4 and 6 values of pH), initial concentration of wastewater (1, 5, and 10 mg/L), contact time (10 min), adsorbent quantity (0.1, 0.5, and 1 g), and isotherm models (Langmuir and Freundlich). The highest wastewater treatment efficiency was obtained at the 6 pH value. The determination of four anti-inflammatory drugs, frequently monitored in wastewater, was performed by a simple and fast method using the HPLC-technique-type DAD (diode array detector). The method was linear when the concentration ranged between 0.5 and 20 m/L for all compounds. The equilibrium concentration was obtained after 8 min. The octanol/water coefficient influenced the removal efficiency of the four drugs by the adsorbent material (activated carbon). The dose of activated carbon (0.1 to 1 g) significantly influenced the efficiency of wastewater treatment, which increased considerably when the dose of the adsorbent material increased. Using 1 g of the adsorbent material for the treatment of wastewater containing 1 mg/L initial concentration of pollutant compounds, the efficiencies were 98% for acetaminophen, 92% for diclofenac, 88% for ketoprofen and 96% for ibuprofen.

scholarly journals Nitrogen-doped carbon materials with cubic ordered mesostructure: low-temperature autoclaving synthesis for electrochemical supercapacitor and CO2 capture

RSC Advances ◽  
2017 ◽  
Vol 7 (21) ◽  
pp. 12524-12533 ◽  
Author(s):  
Lei Liu ◽  
Shi-Da Xu ◽  
Feng-Yun Wang ◽  
Yue-Jun Song ◽  
Jie Liu ◽  
...  
Keyword(s):  
Low Temperature ◽  
Co2 Capture ◽  
Carbon Materials ◽  
Mesoporous Carbons ◽  
Body Centered Cubic ◽  
Ordered Mesoporous Carbons ◽  
Nitrogen Doped ◽  
Electrochemical Supercapacitor ◽  
Ordered Mesoporous ◽  
Nitrogen Doped Carbon

Nitrogen doped ordered mesoporous carbons with a 3-D body-centered cubic pore structure have been synthesized by means of a low-temperature autoclaving route under basic conditions, showing excellent performances for supercapacitors and CO2 capture.

A comparative study of ordered mesoporous carbons with different pore structures as anode materials for lithium-ion batteries

RSC Advances ◽  
2015 ◽  
Vol 5 (53) ◽  
pp. 42922-42930 ◽  
Author(s):  
Diganta Saikia ◽  
Tzu-Hua Wang ◽  
Chieh-Ju Chou ◽  
Jason Fang ◽  
Li-Duan Tsai ◽  
...  
Keyword(s):  
Comparative Study ◽  
Lithium Ion Batteries ◽  
Anode Materials ◽  
Rate Capability ◽  
Lithium Ion ◽  
Reversible Capacity ◽  
Cycling Stability ◽  
Mesoporous Carbons ◽  
Ordered Mesoporous Carbons ◽  
Ordered Mesoporous

Ordered mesoporous carbons CMK-3 and CMK-8 with different mesostructures are evaluated as anode materials for lithium-ion batteries. CMK-8 possesses higher reversible capacity, better cycling stability and rate capability than CMK-3.

Adverse reactions with the use of non-steroidal anti-inflammatory drugs

2020 ◽  
pp. 35-50
Author(s):  
M. L. Maksimov ◽  
N. M. Kiseleva ◽  
D. G. Semenikhin ◽  
B. K. Romanov
Keyword(s):  
Risk Factors ◽  
Adverse Reactions ◽  
Effective Prevention ◽  
Chemical Structures ◽  
Wide Range ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Prevention Method ◽  
Effective Medication ◽  
Upper Gastrointestinal

Non-steroidal anti-inflammatory drugs (NSAIDs) are included in a pharmacological group of drugs with different chemical structures providing anti-inflammatory, analgesic and antipyretic actions, as well as antiplatelet action to a certain degree. Unfortunately, NSAIDs can cause a wide range of adverse reactions (AR) posing a serious risk to the health and life of patients. Therefore, the rational use of NSAIDs should include methods for effective prevention of drug complications. Many NSAIDs have a pronounced therapeutic effect, simultaneously causing many undesirable effects, so the drug shall be chosen considering the development of predicted side effects and modern algorithms. According to clinical recommendations, risk factors and administration of safer NSAIDs shall be considered as the main prevention method. Besides, it is possible to protect the patient from the upper gastrointestinal tract complications using proton pump inhibitors. It should be noted that there are no effective medication methods for kidney and liver protection to reduce the risk of NSAID-associated complications.

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