COMPARATIVE EVALUATION OF GUT DECOMPRESSION METHODS IN OPERATIONS ON TOXIC WIDESPREAD PERITONITIS

Author(s):  
V.I. Midlenko ◽  
N.I. Belonogov ◽  
O.V. Midlenko ◽  
A.L. Charyshkin

The aim of the paper is to conduct a comparative assessment of bowel decompression methods in operations on toxic widespread peritonitis. Materials and Methods. The authors examined 162 patients with widespread peritonitis of various etiologies. Using generally accepted methods, they compared treatment results using one of the three methods of intestinal decompression: cecostomy, nasointestinal intubation, and cecostomy with intubation of the small intestine. Results. It was detected that in case of small intestine intubation through the cecostomy (in comparison with other methods), intra-abdominal pressure returned to normal on the 2nd day, and in case of cecostomy or nasointestinal intubation – on the 5th and 7th day, respectively. Also, decrease in intoxication indicators was observed 2 days earlier than usual. Conclusion. Intubation of the small intestine through the cecostoma provides the most adequate intestinal decompression in patients with advanced toxic peritonitis. Early normalization of intra-abdominal pressure in patients with advanced toxic peritonitis improves treatment outcomes. Keywords: widespread peritonitis, intestinal decompression. Цель – сравнительная оценка способов декомпрессии кишечника при операциях по поводу распространённого перитонита в токсической стадии. Материалы и методы. Наблюдали 162 пациента с распространённым перитонитом различной этиологии. С использованием общепринятых методик сравнивались результаты лечения при применении одного из трёх способов декомпрессии кишечника: цекостомии, назоинтестинальной интубации и наложения цекостомы с интубацией тонкой кишки. Результаты. Установлено, что при использовании интубации тонкого кишечника через цекостому, в сравнении с другими применявшимися нами способами, внутрибрюшное давление нормализовалось на второй день, а при использовании цекостомии или назоинтестинальной интубации – на 5-й и 7-й дни соответственно. Также на 2 сут раньше происходило снижение показателей интоксикации. Выводы. Наиболее адекватную декомпрессию кишечника у пациентов с распространённым перитонитом в токсической стадии обеспечивает интубация тонкого кишечника через цекостому. Ранняя нормализация внутрибрюшного давления у пациентов с распространённым перитонитом в токсической стадии позволяет улучшить результаты лечения. Ключевые слова: распространённый перитонит, декомпрессия кишечника.

2012 ◽  
Vol 93 (5) ◽  
pp. 757-759 ◽  
Author(s):  
K V Komarova ◽  
V K Polenichkin ◽  
N N Ratkina

Aim. To study change of electrometric index of fillings and dental inlays marginal adjoining on the border with hard tooth tissues in patients with xerostomia over time. Methods. 40 patients (male - 11, female - 29) aged from 28 to 56 years with xerostomia, in whom 80 dental restorations were completed. Inclusion criteria were the following: signed informed consent, diagnosis of xerostomia, preserved chewing function of mandibular and maxillar teeth, and presence of an antagonist of the examined tooth. Patients were divided into two subgroups (40 patients each) depending on the treatment method used: dental filling (1st group) or dental inlay (2nd group). Both fillings and inlays were made of packed restorative composite Filtek P60. Dental dam was used to isolate restored tooth from saliva. Marginal adjoining control at the border «tooth-composite» was made by «DentEst» (Geosoft, Russia) electrometric device. Comparative evaluation of marginal adjoining quality at «tooth-filling» and «tooth inlay» border was performed at 3, 6, 9 and 12 months after treatment. Results. 10 minutes after treatment mean values of marginal permeability in the first group did not significantly differed from the second group, indicating good marginal adjoining. 3 months after the treatment at electrometry marginal adjoining was incomplete in 1 filling out of 40, compared to the second group where marginal permeability was still good at 12 months after treatment. The functional examination of restored teeth with good marginal adjoining at a period from 3 to 12 months after treatment showed that this number reduced from 98 to 45% in the first group and from 100 to 95% in the second group. Differences between groups were statistically significant. Conclusion. In patients with xerostomia tooth reconstruction using dental inlay is more effective than use of dental filling.


Author(s):  
Mirvasit Karimov ◽  
Abdujabar Akhmatkhodjaev

Comparative assessment of clinical efficiency of omeprazole and rabeprazole in treating gastroesophageal reflux disease (GERD). 65 patients with a verified diagnosis GERD were examined. Comparative clinical investigations of using ofomeprazole and rabeprazole have revealed effectiveness of both drugs in the therapy of GERD. However, rabeprazoleshowed antisecretory action in the earlier periods, providing stable clinical remission of GERD and early scarring of erosivelesions of the esophageal mucosa, compared with omeprazole


2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Mansour Alsaleh ◽  
Noura Alomar ◽  
Monirah Alshreef ◽  
Abdulrahman Alarifi ◽  
AbdulMalik Al-Salman

The widespread adoption of web vulnerability scanners and the differences in the functionality provided by these tool-based vulnerability detection approaches increase the demand for testing their detection effectiveness. Despite the advantages of dynamic testing approaches, the literature lacks studies that systematically evaluate the performance of open source web vulnerability scanners. The main objectives of this study are to assess the performance of open source scanners from multiple perspectives and to examine their detection capability. This paper presents the results of a comparative evaluation of the security features as well as the performance of four web vulnerability detection tools. We followed this comparative assessment with a case study in which we evaluate the level of agreement between the results reported by two open source web vulnerability scanners. Given that the results of our comparative evaluation did not show significant performance differences among the scanners while the results of the conducted case study revealed high level of disagreement between the reports generated by different scanners, we conclude that the inconsistencies between the reports generated by different scanners might not necessarily correlate with their performance properties. We also present some recommendations for helping developers of web vulnerabilities scanners to improve their tools’ capabilities.


2015 ◽  
Vol 2015 ◽  
pp. 1-15 ◽  
Author(s):  
V. Kuznetsov ◽  
G. Fesenko ◽  
A. Andrianov ◽  
I. Kuptsov

This paper presents first results of the INPRO Collaborative Project on Key Indicators for Innovative Nuclear Energy Systems, which has the objective to develop guidance and tools for comparative evaluation of the status, prospects, benefits, and risks associated with development of innovative nuclear technologies for a more distant future. Presented results illustrate expedience of application of the multicriteria decision analysis methods, which are able to provide the added value to comparative assessment of nuclear energy systems. First, the paper presents a short review of the multicriteria decision analysis methods appropriate to support judgment aggregation within comparative evaluations of nuclear energy systems based on key indicators and highlights the methodology to perform such assessments. Second, a set of key indicators elaborated in the INPRO Collaborative Project on Global Architecture of Innovative Nuclear Energy Systems Based on Thermal and Fast Reactors Including a Closed Fuel Cycle (GAINS) were evaluated for comparative evaluation of nuclear energy system evolution scenarios. Third, a numerical example is presented of application of the selected key indicators, methods, and tools for judgment aggregation in comparative assessment of the GAINS nuclear energy systems.


2017 ◽  
Vol 151 (6) ◽  
pp. 1116-1124 ◽  
Author(s):  
Masahiro Nakamura ◽  
Noriaki Kawanabe ◽  
Tomoki Kataoka ◽  
Takashi Murakami ◽  
Takashi Yamashiro ◽  
...  

2019 ◽  
Vol 95 (9) ◽  
pp. 899-902
Author(s):  
Natalia N. Belyaeva ◽  
L. P. Sycheva

Currently the problem of the impact of nanoparticles and nanomaterials on human health remains to be poorly understood. As in our studies of the impact of silver nanoparticles on rats liver as well in works of other researchers there were investigated morphofunctional indices under peroral exposure. Although all researchers took different sizes, doses and concentrations of silver nanoparticles, various exposure time and different stabilizers, the same effects had been obtained, which, however, were occurred under both different doses and time of exposure. However, it was interesting to compare the impact of silver nanoparticles with reference substance - silver sulfate on the mice liver with the previously evaluated effect produced on the rats ’ liver. By ourselves there was executed the morphological comparative evaluation of in vivo oral 2-weeks exposure of 4 concentrations (0.1; 5; 50 and 500 mg/l) of silver nanoparticles with size of 14 nm, stable arabian gum 1:7 by weight, and of 4 similar concentrations of silver sulfate on the liver of male mice СВАхС57В1/6 weighing 25-35g. 2 groups were considered as control: intact mice and mice received gum in water. Results of the exposure were assessed according to 10 morphological and functional indices. The impact of nanosilver was shown to initiate from its concentration of 50 mg/l and to express in the gain of the index of alteration of the cytoplasm of hepatocytes with the increasing in both severity of steatosis and the number of micronecroses, persisting at the same level at concentrations of 500 mg/l and with the elevation of the index of alteration of nuclei of hepatocytes, while the similar effect develops under the influence of silver sulfate at a concentration of 500 mg/l only. The remaining investigated morphofunctional indices did not differ significantly in all groups of mice. Unlike previously executed studies on rats, mice appeared to be sensitive to the effects of nano-silver more than to silver sulfate.


2020 ◽  
pp. 65-72
Author(s):  
K. A. Egiazaryan ◽  
G. D. Lazishvili ◽  
A. P. Ratyev ◽  
I. V. Sirotin ◽  
A. B. But-Gusaim ◽  
...  

The article is devoted to the current trend of modern orthopedics – the surgical treatment of local full-thickness defects in the hyaline cartilage of the knee joint. This pathology is diagnosed in 5-10% of patients with diseases and injuries of the knee joint.Materials and methods: The authors of the article presented one of the most modern and available technologies for the restoration of cartilage defects – the technology of matrix-induced autochondrogenesis (AMIC – autologous matrix-induced chondrogenesis). This operation technique was used in 63 patients. The article presents the indications and technique of surgery, considers possible errors, complications, criteria for evaluating treatment outcomes.Results: treatment outcomes in terms of up to 13 years were studied in 56 patients. Good treatment results were observed in 53 patients. In all cases, high-quality and regeneration of the cartilaginous surface of the femoral condyles was achieved.Conclusion: Analysis of the outcomes of treatment of patients after implantation of collagen membranes in various modifications allows the authors of the article to recommend this technique for widespread use in clinical practice.


2021 ◽  
Vol 24 (1) ◽  
Author(s):  
Xizhong Chen ◽  
Di Peng ◽  
John P. Morrissey ◽  
Jin Y. Ooi

AbstractBonded contact models have been increasingly used in the discrete element method (DEM) to study cemented and sintered particulate materials in recent years. Several popular DEM bond models have been proposed in the literature; thus it is beneficial to assess the similarities and differences between the different bond models before they are used in simulations. This paper identifies and discusses two fundamental types of bond models: the Spring Bond Model where two bonded particles are joined by a set of uniform elastic springs on the bond’s cross-section, and the Beam Bond Model in which a beam is used to connect the centres of two particles. A series of cantilever beam bending simulation cases were carried out to verify the findings and assess the strength and weakness of the bond models. Despite the numerous bond models described in the literature, they can all be considered as a variation of these two fundamental model types. The comparative evaluation in this paper also shows that all the bond models investigated can be unified to a general form given at a predefined contact point location.


2020 ◽  
Vol 2 (7) ◽  
pp. 130-140
Author(s):  
D. V. GORDIENKO ◽  

The paper considers indicators and criteria for assessing the level of protection of the national economy in the context of the spread of viral infection. An approach to determining the significance of standardized indicators of economic security of the state for various stages of the spread of viral infection is presented. An approach to the comparative assessment of the level of protection of the national economy in the context of the spread of viral infection for the States of the strategic triangle Russia – China – USA is proposed. This allows us to identify the priorities of Russia's economic policy and justify recommendations to the political leadership of our country to combat COVID-19 coronavirus infection.


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