ENDOSCOPIC ULTRASOUND IN DIAGNOSIS OF GASTROINTESTINAL AND PANCREATICOBILIARY DISEASES

2019 ◽  
pp. 87-95
Author(s):  
Van Huy Tran ◽  
Khanh Vinh
Keyword(s):  
Endoscopic Ultrasound ◽  
Pancreas Cancer ◽  
Submucosal Tumor ◽  
Gastrointestinal Diseases ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Endoscopy Ultrasound ◽  
Tract Dilation ◽  
Subepithelial Lesions ◽  
Immediate Bleeding

Background and aims: Data about endoscopic ultrasound in our country was still limited. This study aimed to evaluate the efficacy and safety of endoscopy ultrasound for diagnosis of gastrointestinal and pancreaticobiliary diseases. Patients and methods: A cross - sectional study was conducted on 1176 patients undergoing endoscopy ultrasound to diagnose gastrointestinal- pancreaticobiliary diseases. Results: Study on a total of 1176 patients indicated for endoscopic ultrasound. We have some following results: Gastrointestinal diseases. The submucosal tumor was about 55,74% and gastrointestinal cancer was 44.26%. The local of submucosal tumor: 52.93% with gastric subepithelial lesions, 33.46% oesophageal, 11.67% duodenum and 1.94% from the colorectal. The esophagus cancer was 37.27%, colorectal cancer was 36.27%, gastric cancer was 24.01% and duodenum cancer was 2.45%. Pancreaticobiliary diseases: The common bile duct stone was 68.89%, Biliary tract dilation of unknown cause was 9.64%, vater tumor was 9.42%, cholangioma was 7.89%, billiary diseases was caused by paradise and billiary cyst was 1.97%. Pancreas diseases: 43.25% with chronic pancreatitis, 31.66% pancreas cancer, 17.76% acute pancreatitis and 7.33% pancreas cyst. EUS-FNA for pancreas cancer was about 80% and IPMN was 20%. Complication of hypoxia found in 0.34% and only 1 case of immediate bleeding after EUS-FNA. Conclusions: Endoscopic ultrasound is a highly effective and relatively safe method of diagnosis for gastrointestinal- pancreaticobiliary diseases. Key words: endoscopic ultrasound, gastrointestinal and pancreaticobiliary diseases

ENDOSCOPIC ULTRASOUND IN THE DIAGNOSIS OF GASTROINTESTINAL SUBMUCOSAL TUMORS AT HUE UNIVERSIY OF MEDICINE AND PHARMACY HOSPITAL

2019 ◽  
pp. 17-20
Author(s):  
Van Huy Tran ◽  
Thanh Long Nguyen
Keyword(s):  
Endoscopic Ultrasound ◽  
Submucosal Tumor ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Men And Women ◽  
Submucosal Tumors ◽  
Endoscopy Ultrasound ◽  
Colon And Rectum ◽  
The Mean

Background: Diagnosis of gastrointestinal submucosal tumors (SMT) is still a challenge in clinical practice and data about gastrointestinal submucosal tumors in our country was very limited. This study aimed to assess some characteristics of gastrointestinal submucosal tumors. Patients and Methods: cross–sectional study; 195 patients having gastrointestinal submucosal tumors diagnosed by endoscopic ultrasound at Hue University of Medicine and Pharmacy Hospital were enrolled from October 2013 to December 2018. Cutting biopsy or EUS- FNA in case necessary. Results: The mean age of patients was 48.92 ± 15.23. The prevalence was nearly equal in men and women with 48.2% and 51.8%, respectively. According to location, submucosal tumors were 45.6% in the stomach, 35.9% in the esophagus and 2.6% in the colon and rectum. According to etiology, the submucosal cyst was found in 23.6%, the leiomyoma was 22.1%, the Brunner’s gland was 1% and the unknown submucosal tumors was 19.5%. 58.1% of the leiomyoma and 67.4% of the submucosal cyst were found in the esophagus. 76% of the GIST, 83.3% of the ectopic pancreas and 64.7% of the lipoma were found in stomach. Conclusions: Based on endoscopy ultrasound, the most common locations of SMT were stomach and esophagus; the most common SMT were submucosal cyst and leiomyoma. Key words: Submucosal tumor (SMT), Endoscopic ultrasound (EUS)

THE ROLE OF ENDOSCOPIC ULTRASOUND IN DIAGNOSIS OF CHRONIC PANCREATITIS

2018 ◽  
pp. 20-26
Author(s):  
Van Huy Tran ◽  
Trung Nam Phan ◽  
Khanh Vinh
Keyword(s):  
Chronic Pancreatitis ◽  
Pancreatic Duct ◽  
Endoscopic Ultrasound ◽  
Main Pancreatic Duct ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Endoscopy Ultrasound ◽  
Pancreatic Duct Stone

Background and aims: To evaluate the efficacy of endoscopic ultrasound for diagnosis chronic pancreatitis by Rosemont classification. Patients and methods: A cross – sectional study was conducted on patients undergoing endoscopy ultrasound to diagnose chronic pancreatitis. Results: Study on a total of 57 patients indicated for endoscopic ultrasound. We have some following results: The lesions of chronic pancreatitis on endoscopic ultrasound: The hyperechoic foci without shadowing and stranding is 82.5% and hyperechoic foci with shadowing is 70.2%, cyst and pseudocyst are about 15.8%. Main pancreatic duct dilation is 71.9%, hyperechoic main pancreatic duct wall is 70.2%, main pancreatic duct stone is about 45.6%. Rosemont classification in diagnosis of chronic pancreatitis: Consistent with chronic pancreatitis by 1 major A feature (+) ≥ 3 minor features is 69.4% and 2 major A features is 30,6%. Suggestive of chronic pancreatitis by over 5 minor features is 100%. EUS is more accurate than CT in detecting early chronic pancreatitis. Conclusions:Endoscopic ultrasound is a highly effective method of diagnosing chronic pancreatitis. Key words: chronic pancreatitis, endoscopic ultrasound

THE PRIMARY RESEARCH: THE ROLE OF ENDOSCOPIC ULTRASOUND IN DIAGNOSIS OF CHRONIC PANCREATITIS

2017 ◽  
pp. 40-47
Author(s):  
Khanh Vinh ◽  
Van Huy Tran
Keyword(s):  
Chronic Pancreatitis ◽  
Pancreatic Duct ◽  
Endoscopic Ultrasound ◽  
Main Pancreatic Duct ◽  
Cross Sectional Study ◽  
Primary Research ◽  
Cross Sectional ◽  
Endoscopy Ultrasound ◽  
Pancreatic Duct Stone

Background and aims: To evaluate the efficacy of endoscopy ultrasound for diagnosis chronic pancreatitis by Rosemont classification. Patients and methods: A cross - sectional study was conducted on 44 patients undergoing endoscopy ultrasound to diagnose chronic pancreatitis. Results: Study on a total of 44 patients indicated for endoscopic ultrasound. We have some following results: The lesions of chronic pancreatitis on endoscopic ultrasound: The hyperechoic foci without shadowing and stranding was 79.5% and hyperechoic foci with shadowing was 72.7%, cyst and pseudocyst were about 13.6%. Main pancreatic duct dilation is 75%, hyperechoic main pancreatic duct wall was 72.7%, main pancreatic duct stone and irregular main pancreatic duct contour were about 52.2%. Rosemont classification in diagnosis of chronic pancreatitis: Consistent with chronic pancreatitis by 1 major A feature (+) ≥ 3 minor features is 67.5% and 2 major A features is 32.5%. Suggestive of chronic pancreatitis by over 5 minor features is 100%. EUS is more accurate than CT in detecting early chronic pancreatitis. Conclusions: Endoscopic ultrasound is a highly effective method of diagnosing chronic pancreatitis. Key words: endoscopy ultrasound, chronic pancreatitis

scholarly journals Pattern of upper gastrointestinal diseases: an audit of 1000 cases based on endoscopic findings from a tertiary care hospital in Mysore

2018 ◽  
Vol 5 (7) ◽  
pp. 2412
Author(s):  
Shashikumar H. B. ◽  
Madhu B. S. ◽  
Motati Harshini
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Gastrointestinal Symptoms ◽  
Gastrointestinal Diseases ◽  
Cross Sectional Study ◽  
Common Finding ◽  
Care Hospital ◽  
Cross Sectional ◽  
Endoscopic Findings ◽  
Upper Gastrointestinal

Background: Fibreoptic endoscopy is a highly efficient diagnostic tool, which is now increasingly being used in the diagnosis of upper gastrointestinal diseases. This study has been carried out to evaluate the distribution of various upper gastrointestinal diseases based on endoscopic findings in a tertiary care hospital in Mysore.Methods: A cross-sectional study was conducted based on data from endoscopic register of 1000 subjects who underwent endoscopy for various upper gastrointestinal symptoms from 1st January 2017 to 31st December 2017(one year).Results: Mean age of the study population was 50.23 years (SD-15.46). Minimum age was 12 years and maximum was 88 years. About 44.7% of the study subjects belonged to 40-60 age group.61.6% of the study subjects were males. Most common indication was pain abdomen (32.1%) followed by dysphagia (22.2%). Of the 1000 study subjects 18.6% had normal findings. Most common finding was Gastritis / Duodenitis /Gastric erosions (28%). Malignant lesions were noted among 11.1%, of which esophagus and stomach are 5.4% and 4.9% respectively.Conclusions: Endoscopic diagnosis is useful for early detection of UGI diseases and helpful for their management.

scholarly journals Endoscopic Ultrasound Findings in Patients Diagnosed with Exocrine Pancreatic Insufficiency by Low Fecal Elastase-1

2019 ◽  
Vol 2019 ◽  
pp. 1-5 ◽  
Author(s):  
Mazen Shobassy ◽  
Nedaa Husainat ◽  
Abdalaziz Tabash ◽  
Kalpesh Patel ◽  
Hashem B. El-Serag ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Endoscopic Ultrasound ◽  
Pancreatic Insufficiency ◽  
Cross Sectional Study ◽  
Lifestyle Factors ◽  
Exocrine Pancreatic Insufficiency ◽  
Cross Sectional ◽  
Fecal Elastase ◽  
Elastase 1 ◽  
Pancreatic Neoplasia

Background and Aims. Fecal elastase-1 (FE-1) as a screening test for exocrine pancreatic insufficiency (EPI) is gaining popularity in clinical practice. The role of imaging in patients with FE-1-related suspicion of EPI remains unclear. The aim of this study was to characterize endoscopic ultrasound (EUS) findings for patients with low FE-1. Methods. A retrospective cross-sectional study was performed in 40 patients who had low FE-1 and underwent EUS to evaluate the pancreas. We obtained data on demographic and lifestyle factors, EUS findings, and histopathology results. We compared these variables between patients with FE‐1<100 mcg/g vs. 100-200 mcg/g. Results. Most patients (82.5%) established one or more new diagnoses from EUS. Diagnoses included: definitive chronic pancreatitis (n=29, 72.5%), fatty pancreas (n=9, 22.5%), and pancreatic solid mass or cyst (n=9, 22.5%). Half (n=4) of the solid or cystic lesions were neoplastic. All patients with a solid pancreatic mass also had concurrent chronic pancreatitis. There were no significant differences in EUS findings or demographic or lifestyle factors between groups with FE‐1<100 mcg/g vs. 100-200 mcg/g. Conclusion. Chronic pancreatitis is the most common EUS finding in patients with low FE-1 levels. EUS appears helpful in determining the cause of EPI in most patients with low FE-1 and may detect unsuspected pancreatic neoplasia.

scholarly journals Defining the endoscopic ultrasound features of chronic pancreatitis in Asians: a multicenter validation study

Endoscopy ◽  
2020 ◽  
Author(s):  
Calvin Jianyi Koh ◽  
Sundeep Lakhtakia ◽  
Mitsuhiro Kida ◽  
Cosmas Rinaldi A. Lesmana ◽  
Tiing Leong Ang ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Pancreatic Duct ◽  
Endoscopic Ultrasound ◽  
Main Pancreatic Duct ◽  
Cross Sectional Study ◽  
Cancer Surveillance ◽  
Receiver Operating Curve ◽  
Cross Sectional ◽  
Multicenter Prospective Study ◽  
Ultrasound Features

Background Although endoscopic ultrasound (EUS) features and criteria have been described in chronic pancreatitis, challenges remain with interoperator variability and ease of adoption. The aim of this study was to define and validate the EUS features of chronic pancreatitis in a multicenter prospective study in Asia. Method The study was divided into two parts: the first part was conducted to derive the EUS features of chronic pancreatitis with adequate interoperator agreement; the second was to prospectively evaluate these features in a multicenter cross-sectional study and determine the optimal combination of features for the diagnosis of chronic pancreatitis. Prospectively enrolled cases had standard internationally validated radiologic or histologic features of chronic pancreatitis, and controls were patients without chronic pancreatitis who underwent EUS examination. Results The top six EUS features that had good interobserver agreement (mean kappa 0.73, range 0.60 – 0.90) were selected to be further evaluated in part II of the study. These included: hyperechoic foci with shadowing, lobularity with honeycombing, cysts, dilated main pancreatic duct, dilated side branches, and calculi in the main pancreatic duct. A total of 284 subjects (132 cases, 152 controls) were enrolled from 12 centers in Asia. All six features had high accuracy ranging from 63.3 % to 89.1 %. Two or more of these six EUS features accurately defined chronic pancreatitis (sensitivity 94.7 %, specificity 98.0 %), with an area under the receiver operating curve of 0.986. Conclusion This multicenter Asian study characterized and defined the EUS features of chronic pancreatitis. This provides a useful tool in clinical practice and further research in pancreatic cancer surveillance.

scholarly journals Lactulose Hydrogen Breath Test Result Is Associated with Age and Gender

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Carolyn Newberry ◽  
Ann Tierney ◽  
Octavia Pickett-Blakely
Keyword(s):  
Breath Test ◽  
Bacterial Overgrowth ◽  
Gastrointestinal Diseases ◽  
Small Intestinal Bacterial Overgrowth ◽  
Cross Sectional Study ◽  
Hydrogen Breath Test ◽  
Cross Sectional ◽  
Lactulose Hydrogen Breath Test ◽  
Significant Difference ◽  
And Gender

Small intestinal bacterial overgrowth (SIBO) is associated with chronic gastrointestinal diseases and structural/functional abnormalities of the gastrointestinal tract. SIBO’s association with clinical characteristics is unclear. This study investigates the association between clinical factors and SIBO according to lactulose hydrogen breath test (LHBT) result.Methods. A cross-sectional study in a university-based gastroenterology practice was performed. Data was abstracted from the medical records of subjects undergoing LHBT from 6/1/2009 to 6/1/2013. Logistic regression analysis was performed to determine the association between predictor variables: age, sex, body mass index (BMI), and positive LHBT, the outcome of interest.Results. LHBT was performed in 791 subjects. Fifty-four percent had a positive LHBT. There was no statistically significant difference between the LHBT results according to age or BMI. In females, the likelihood of a positive LHBT increased with age (OR 1.02; 95% CI: 1.01–1.03). In males, the likelihood of a positive LHBT result decreased with age (OR 0.98; 95% CI: 0.97–1.00).Conclusion. There was an association between age, with respect to sex, and a positive LHBT. With increased age in females, the odds of a positive LHBT increased, while, in men, the odds of a positive LHBT decreased with age.

The indications for performing colonoscopy in Iranian children – a cross-sectional study

2021 ◽  
Vol 75 (6) ◽  
pp. 515-518
Author(s):  
Seyed Mohsen Dehghani ◽  
Mahshid Doosti ◽  
Iraj Shahramian ◽  
Hadi Mirzaie ◽  
Fateme Parooie ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Rectal Bleeding ◽  
Bowel Disease ◽  
Gastrointestinal Diseases ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Inflammatory Bowel ◽  
Iranian Children ◽  
Colon Diseases

Background: Colonoscopy is the gold standard dia­gnostic method for colon diseases providing an excellent view of the mucosal surface of the colon and terminal ileum. Colonoscopy in children is indicated for dia­gnosis and treatment of gastrointestinal diseases. In this study, we evaluated the reasons for performing colonoscopy in children. Methods: This was a descriptive cross-sectional study including all children referred for colonoscopy to the Gastroenterology clinic affiliated with the Shiraz University of Medical Sciences. The children were selected by a convenient sampling method. Statistical analysis was conducted in the SPSS 22 software. Results: From 389 children referred for colonoscopy, 203 were boys and 186 were girls. The mean age was 8.36 ±4.8 years. The most common reason for colonoscopy was rectal bleeding (63.5%) with the most prevalent dia­gnoses being juvenile polyp and inflammatory bowel disease, each accounting for 11.3% patients. Conclusions: The most common findings of colonoscopy were polyp, IBD and colon inflammation, and the most prevalent symptoms leading to colonoscopy were rectal bleeding, chronic diarrhea, IBD treatment follow-up, suspected IBD and abdominal pain. The high prevalence of pediatric patients presenting with these symptoms indicates the increasing importance of colonoscopy in these patients. Keywords colonoscopy, gastrointestinal bleeding, inflammatory bowel disease, gastrointestinální onemocnění

scholarly journals Older adults hospitalized in a teaching hospital: clinical characteristics and outcomes

2017 ◽  
Vol 11 (12) ◽  
pp. 4938
Author(s):  
Camilla Christina Rodrigues ◽  
Rita de Cássia Helú Mendonça Ribeiro ◽  
Claudia Bernardi Cesarino ◽  
Daniela Comelis Bertolin ◽  
Renato Mendonça Ribeiro ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Older Adult ◽  
Average Length ◽  
Descriptive Analysis ◽  
Length Of Hospital Stay ◽  
Gastrointestinal Diseases ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Sample Characterization

RESUMOObjetivo: investigar as causas de internação dos idosos hospitalizados, o perfil demográfico, o perfil clínico e o desfecho. Método: estudo quantitativo, transversal de análise de 14.892 prontuários eletrônicos, no período de 12 meses. Foi realizada uma análise descritiva das variáveis de caracterização amostral e aplicação do teste associativo pela estatística qui-quadrado. Resultados: a maioria dos pacientes avaliados era do sexo masculino, com grau de instrução fundamental, com companheiro, do lar, brancos, católicos e com doenças cardiovasculares, seguidas de neoplasias e doenças gastrointestinais em ambos os sexos.  A idade dos pacientes apresentou média de 72,1 anos e a média da permanência hospitalar foi de 5,9 dias. Houve associação significativa entre as doenças diagnosticadas, o sexo (p <0,001) e a etnia (p = 0,023) dos pacientes. O desfecho mais comum foi a alta dos pacientes. Conclusão: as doenças crônicas foram as principais causas de hospitalização dos idosos, acarretando mais tempo na hospitalização. A investigação destes fatores fornece subsídios para identificação dos problemas e realizar melhores ações de enfermagem. Descritores: Idoso; Hospitalização; Evolução Clínica.ABSTRACT Objective: to investigate the causes of older adult hospitalizations, demographic and clinical profiles, and patient outcome. Method: quantitative cross-sectional study conducted with 14,892 electronic medical records during 12 months. We carried out a descriptive analysis of the variables of the sample characterization, and an associative test using chi-square statistics. Results: most patients assessed were male, had primary education, lived with a partner, were white and Catholics, and had cardiovascular diseases, followed by neoplasms and gastrointestinal diseases in both sexes. The average age of the patients was 72.1 years, and the average length of hospital stay was 5.9 days. There was a significant association between diagnosed diseases, sex (p <0.001), and ethnicity (p = 0.023) of the patients. The most common outcome was hospital discharge. Conclusion: chronic diseases were the main causes of older adult hospitalizations and led to increased length of hospital stay. The assessment of these factors provides subsidies for identifying problems and performing best nursing interventions. Descriptors: Older Adult; Hospitalization; Clinical Evolution.RESUMEN Objetivo: investigar las causas de hospitalización de adultos mayores, perfil demográfico, perfil clínico y desenlaces. Método: estudio cuantitativo transversal con análisis de 14.892 registros médicos electrónicos de un período de 12 meses. Se realizó un análisis descriptivo de las variables de caracterización de la muestra y se aplicó la prueba chi-cuadrado. Resultados: la mayoría de los pacientes evaluados eran hombres, con educación primaria, vivían en pareja, eran blancos, católicos y tenían enfermedades cardiovasculares, seguidas de neoplasias y enfermedades gastrointestinales en ambos sexos. El promedio de edad de los pacientes fue de 72,1 años y de la estancia hospitalaria fue de 5,9 días. Hubo una asociación significativa entre enfermedades diagnosticadas, sexo (p <0.001) y etnia (p = 0.023) de los pacientes. El resultado más común fue el alta hospitalaria. Conclusión: las enfermedades crónicas fueron las principales causas de hospitalización de los adultos mayores, llevando a un tiempo más prolongado de internación. La investigación de estos factores proporciona subsidios para identificación de problemas y realizar mejores intervenciones de enfermería. Descritores: Adulto Mayor; Hospitalización; Evolución Clínica.

Clinical Usefulness of Endoscopic Ultrasound-Guided Fine Needle Aspiration for Gastric Subepithelial Lesions Smaller than 2 cm

2014 ◽  
Vol 23 (4) ◽  
pp. 405-412 ◽  
Author(s):  
Kazuya Akahoshi ◽  
Masafumi Oya ◽  
Tadashi Koga ◽  
Hidenobu Koga ◽  
Yasuaki Motomura ◽  
...  
Keyword(s):  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Submucosal Tumor ◽  
Needle Aspiration ◽  
Clinical Usefulness ◽  
Ultrasound Guided ◽  
High Power Field ◽  
Early Management ◽  
Fine Needle ◽  
Subepithelial Lesions

Background & Aims: There is no evidence of postoperative metastasis of gastric gastrointestinal stromal tumors (GISTs) smaller than 2 cm. The aim of this study was to evaluate the clinical usefulness of endoscopic ultrasound guided fine needle aspiration (EUS-FNA) for gastric subepithelial lesions (SELs) smaller than 2 cm.Patients and methods: Using a prospectively maintained EUS-FNA database, 90 consecutive EUS-FNAs of gastric hypoechoic solid SELs smaller than 2 cm diagnosed by EUS were evaluated retrospectively. The reference standards for the final diagnosis were surgery (n=44) and/or clinical follow-up (n=46) using esophagogastroduodenoscopy (EGD), CT, and/or ultrasonography (US). Additionally, immunophenotyping of specimens obtained by EUS-FNA and surgical resection specimens were compared.Results: The diagnostic rate of EUS-FNA for gastric hypoechoic solid SELs smaller than 2 cm was 73% (66/90). Histological diagnosis of EUS-FNA showed 47 (52%) malignant SELs (44 GISTs, 1 glomus tumor, 1 SEL like cancer, and 1 malignant lymphoma), 19 (21%) benign SELs (14 leiomyomas, 4 ectopic pancreas, and 1 neurinoma), and 24 (27%) indeterminate SELs. In 44 surgically resected cases, the diagnostic accuracy of EUS-FNA using immunohistochemical analysis was 98% (43/44). There were no complications. Appropriate 5 out of 66 SELs (98%) diagnosed by definitive EUS-FNA. After surgery, there was no recurrence of malignant SELs.Conclusions: EUS-FNA is an accurate and safe method in the pre-therapeutic diagnosis of gastric SELs smaller than 2 cm. EUS-FNA for gastric SELs smaller than 2 cm is a promising way to permit early management of patients with gastric SELs including GIST.Abbreviations: EGD: esophagogastroduodenoscopy; EUS: endoscopic ultrasonography; EUS-FNA:endoscopic ultrasound-guided fine needle aspiration; GIST: gastrointestinal stromal tumor; HPF: high power field; SEL: subepithelial lesion; SMT: submucosal tumor.

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