Faculty Opinions recommendation of Modifiable Lifestyle and Environmental Factors Associated with Onset of Psoriatic Arthritis in Patients with Psoriasis: A Systematic Review and Meta-Analysis of Observational Studies.

SUMMARYThe objective of this systematic review and meta-analysis was to estimate the proportion of cases of non-typhoidal salmonellosis (NTS) that develop chronic sequelae, and to investigate factors associated with heterogeneity. Articles published in English prior to July 2011 were identified by searching PubMed, Agricola, CabDirect, and Food Safety and Technology Abstracts. Observational studies reporting the number of NTS cases that developed reactive arthritis (ReA), Reiter's syndrome (RS), haemolytic uraemic syndrome (HUS), irritable bowel syndrome (IBS), inflammatory bowel disease (IBD) or Guillain–Barré syndrome (GBS), Miller–Fisher syndrome (MFS) were included. Meta-analysis was performed using random effects and heterogeneity was assessed using the I2 value. Meta-regression was used to explore the influence of study-level variables on heterogeneity. A total of 32 studies were identified; 25 reported on ReA, five reported on RS, seven reported on IBS, two reported on IBD, two reported on GBS, one reported on MFS, and two reported on HUS. There was insufficient data in the literature to calculate a pooled estimate for RS, HUS, IBD, GBS, or MFS. The pooled estimate of the proportion of cases of NTS that developed ReA and IBS had substantive heterogeneity, limiting the applicability of a single estimate. Thus, these estimates should be interpreted with caution and reasons for the high heterogeneity should be further explored.

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Risk Factors for Colonization and Infection With Resistant Pseudomonas Aeruginosa in Intensive Care Unit: Protocol for a Systematic Review and Meta-analysis

10.21203/rs.3.rs-287779/v1 ◽

2021 ◽

Author(s):

Serge Eyebe ◽

Hugues Nana-Djeunga ◽

Magellan Guewo-Fokeng ◽

Guy Sadeu Wafeu ◽

Marius Wouking ◽

...

Keyword(s):

Risk Factors ◽

Systematic Review ◽

Intensive Care Unit ◽

Pseudomonas Aeruginosa ◽

Intensive Care ◽

Environmental Factors ◽

Meta Analysis ◽

Cochrane Library ◽

Prevalence Odds Ratio ◽

Factors Associated

Abstract Background: Infection with resistant Pseudomonas aeruginosa (RPA) in Intensive Care Unit (ICU) is known to be either endogenous or exogenous or both, but the roles of each of these contamination routes is yet to be clarified. Data regarding prevalence, risk factors and environmental factors associated with RPA in ICU are very scanty and even when they exist, they seem to be contradictory. So, there is a strong interest in understanding both individual and environmental factors associated with RPA infection. This systematic review aims to investigate individual and environmental factors associated with the colonization and infection with RPA in ICU.Methodology: MEDLINE (Pubmed), EMBASE (OVID), the Cochrane Library (Wiley), Web of Science, CINAHL (EBSCOHost) and LILACS (BIREME) will be searched from inception onwards. Grey literature will be identified through Google Scholar and open Grey. Two reviewers will independently screen all citations, abstracts and full-text articles. Potential conflicts will be resolved through discussion. Methodological quality including bias will be appraised using appropriate approaches. A narrative synthesis will describe quality and content of the epidemiological evidence. Prevalence, Odds ratio, Relative Risk, Hazard radio with their respective 95% confidence intervals will be calculated. A meta-analysis of data extracted from eligible studies with similar population and RPA testing will be performed. The analysis will evaluate factors influencing the estimates. A random effect model will be used to summarize effect sizes.Discussion: Two contrasting hypotheses on risk factors of acquisition, colonisation, and infection of RPA are being debated, especially in a context where available data are scanty or exhibit high discrepancy. Indeed, most of the reviews have been focalized on hospitalised patients, and not in ICU, and few of them really address the environmental factors issue. To fill that gap, this review will combine both analysis of individual and environmental risk factors using prevalence study in ICU and evaluation of different methodologies. These two hypotheses will be tested and challenged, and could serve as a basis for a more in-depth studies to fill the methodological gaps that will be identified as part of this current review.Systematic review registration: This protocol has been submitted registered with Prospective Register of Systematic Reviews (PROSPERO) on 07 march 2021 under number CRD42021233832

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Bone Mineral Density, Osteoporosis, and Fracture Risk in Adult Patients with Psoriasis or Psoriatic Arthritis: A Systematic Review and Meta-Analysis of Observational Studies

Journal of Clinical Medicine ◽

10.3390/jcm9113712 ◽

2020 ◽

Vol 9 (11) ◽

pp. 3712

Author(s):

Tai-Li Chen ◽

Jing-Wun Lu ◽

Yu-Wen Huang ◽

Jen-Hung Wang ◽

Kuei-Ying Su

Keyword(s):

Bone Mineral Density ◽

Systematic Review ◽

Psoriatic Arthritis ◽

Bone Mineral ◽

Observational Studies ◽

Meta Analysis ◽

Mineral Density ◽

Psoriatic Disease ◽

Increased Risk ◽

Significant Difference

Introduction: Awareness of psoriasis-related comorbidities has been established in the current guidelines; however, evidence regarding the association of bone density or bone fragility with psoriatic disease remains inconclusive. Methods: We conducted a systematic review and meta-analysis to assess bone mineral density and the risk of osteoporosis and fractures in patients with psoriatic disease, including those with cutaneous psoriasis and psoriatic arthritis. We searched electronic databases for published observational studies. A meta-analysis was performed using the random-effect model. Pooled estimates and their confidence intervals (CIs) were calculated. Small-study effects were examined using the Doi plot and Luis Furuya–Kanamori index. Results: The analysis of the standardized mean difference in the absolute value of bone mineral density at different measuring sites (lumbar spine, femoral neck, and total hip) revealed no significant difference between patients with psoriatic disease and non-psoriatic controls. The pooled results of the adjusted odds ratios (ORs) demonstrated no increased risk of osteoporosis in patients with psoriatic disease. Notably, patients with psoriatic disease had a higher OR of developing bone fractures (adjusted OR: 1.09; 95% CI: 1.06 to 1.12; I2: 0%). Conclusion: Patients with psoriatic disease may be more likely to develop fractures compared with non-psoriatic controls. This higher risk for fracture may not necessarily be associated with lower bone mineral density nor a higher risk for osteoporosis.

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Factors related to lower limb performance in children and adolescents aged 7 to 17 years: A systematic review with meta-analysis

PLoS ONE ◽

10.1371/journal.pone.0258144 ◽

2021 ◽

Vol 16 (10) ◽

pp. e0258144

Author(s):

Paulo Francisco de Almeida-Neto ◽

Vitória Monteiro Monte Oliveira ◽

Dihogo Gama de Matos ◽

Ísis Kelly dos Santos ◽

Adam Baxter-Jones ◽

...

Keyword(s):

Systematic Review ◽

Lower Limb ◽

Observational Studies ◽

Literature Search ◽

Meta Analysis ◽

Lower Limbs ◽

Chronological Age ◽

Eligibility Criteria ◽

Factors Associated ◽

Puberty Stages

Background The literature identifies several factors that are associated with lower limb performance (LLP). However, there is little consensus on which factors have the major associations with LLP. Objective Examine, analyze and summarize the scientific evidence on the factors associated with the performance of LLP in children and adolescents of both sexes aged between 7 and 17 years. Design This systematic review was conducted following the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) statement and was registered in PROSPERO. Data sources A systematic literature search of five electronic databases (i.e., SPORTDiscus, PubMed, CINAHL, Google Scholar, and SCOPUS) with date restrictions was conducted (2010 to 2021). Eligibility criteria for selecting studies Eligibility criteria included (i) a study published between 2010 and 2021; (ii) a research study with observational design; (iii) a study analyzing LLP; and (iv) a sample composed of young people between 7 and 17 years old (regardless of sex). Analyses Literature analysis was carried out in English and Portuguese between 2018 and 2021, “blindly” by two researchers. For data sorting, Rayyan® was used. Data extraction and evidence analysis were performed “blindly”, using the Loney scale. The minimum items for observational studies were analyzed by the STROBE checklist. Meta-analyses were conducted based on age group (Childhood [7 to 11 Yrs] and Adolescence [12 to 17 Yrs]) and puberty stages (i.e., Prepupertal and Pubertal). The heterogeneity between the samples of the studies was assessed using the “Cochran’s Q” and “I^2” statistics. Meta-regression analyses were performed to check the factors related to heterogeneity of the studies and to check the associations between chronological age and LLP. Results The literature search resulted in 1,109,650 observational studies of which 39 were included in this review. Through Meta-analysis and Meta-regressions, it was possible to indicate that advancing chronological age related to increased LLP (p<0.01), and that in relation to puberty stages pubertal subjects had higher LLP than their pre-pubertal peers (p<0.01). Discussion The main findings of the present systematic review suggest that as chronological age advances (childhood to adolescence), neuromuscular systems mature and this may be due to advancing puberty, which is also associated with an increase in LLP. Conclusion The factors associated with lower limbs performance are still inconsistent in the literature. However, advancing chronological age and stage of puberty are both associated with increased lower limbs performance. Trial registration ID-PROSPERO-CRD42020137925.

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The association between dietary inflammatory index and risk of central obesity in adults: An updated systematic review and meta-analysis

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000648 ◽

2020 ◽

Vol 90 (5-6) ◽

pp. 535-552 ◽

Cited By ~ 2

Author(s):

Mahdieh Abbasalizad Farhangi ◽

Mahdi Vajdi

Keyword(s):

Systematic Review ◽

Observational Studies ◽

Central Obesity ◽

Assessment Tool ◽

Weighted Mean Difference ◽

Meta Analysis ◽

Dietary Factors ◽

Cross Sectional ◽

Inflammatory Status ◽

Obesity Indices

Abstract. Backgrounds: Central obesity, as a pivotal component of metabolic syndrome is associated with numerous co-morbidities. Dietary factors influence central obesity by increased inflammatory status. However, recent studies didn’t evaluate the association between central obesity and dietary inflammation index (DII®) that give score to dietary factors according to their inflammatory potential. In the current systematic review and meta-analysis, we summarized the studies that investigated the association between DII® with central obesity indices in the general populations. Methods: In a systematic search from PubMed, SCOPUS, Web of Sciences and Cochrane electronic databases, we collected relevant studies written in English and published until 30 October 2019. The population of included studies were apparently healthy subjects or individuals with obesity or obesity-related diseases. Observational studies that evaluated the association between DII® and indices of central obesity including WC or WHR were included. Results: Totally thirty-two studies were included; thirty studies were cross-sectional and two were cohort studies with 103071 participants. Meta-analysis of observational studies showed that higher DII® scores were associated with 1.81 cm increase in WC (Pooled weighted mean difference (WMD) = 1.813; CI: 0.785–2.841; p = 0.001). Also, a non-significant increase in the odds of having higher WC (OR = 1.162; CI: 0.95–1.43; p = 0.154) in the highest DII category was also observed. In subgroup analysis, the continent, dietary assessment tool and gender were the heterogeneity sources. Conclusion: The findings proposed that adherence to diets with high DII® scores was associated with increased WC. Further studies with interventional designs are necessary to elucidate the causality inference between DII® and central obesity indices.

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