Relationship between Malocclusion and Heart Rate Variability Indices in Young Adults

2011 ◽  
Vol 50 (04) ◽  
pp. 358-363 ◽  
Author(s):  
N. Takeuchi ◽  
M. Furuta ◽  
T. Tomofuji ◽  
M. Morita ◽  
D. Ekuni
Keyword(s):  
Quality Of Life ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Young Adults ◽  
Chronic Stress ◽  
High Frequency ◽  
Low Frequency ◽  
The Relationship ◽  
Oral Impacts

Summary Objectives: Heart rate variability (HRV) has been used to assess sympathetic and parasympathetic modulation of heart rate. Chronic stress relates to reduced HRV. Malocclusion has effects on quality of life, which can lead to chronic stress. Therefore, we hypothesized that malocclusion, as chronic stress, may contribute to reduced HRV. The aim of this study was to investigate the relationship between malocclusion and HRV indices in healthy young adults. Methods: Thirty-seven non-smoking healthy subjects, aged 22 to 25 years, were examined. Malocclusion was defined by Angle classification. HRV indices included root mean square of successive differences, low frequency (LF), high frequency (HF) and ratio of LF to HF. The effects of malocclusion on quality of life and mental health were assessed using self-reported questionnaires, the condition-specific Oral Impacts on Daily Performances index (CS-OIDP) and the Hopkins Symptoms Checklist (HSCL), respectively. Results: Significantly lower score of HF and higher heart rate (HR) level and CS-OIDP score were observed in subjects with malocclusion (n = 17) compared to those in the control subjects (n = 20) (P < 0.05). There was a positive correlation between HR and score of “anxiety” in HSCL (P < 0.05). Conclusions: The data showed an association between malocclusion and lower HRV. Based on our results, orthodontic treatment might contribute not only to improvement of oral esthetic and functional problems but also to improvement of stress and HRV indices.

Mind–body interactive qigong improves physical and mental aspects of quality of life in inpatients with stroke: A randomized control study

2019 ◽  
Vol 18 (8) ◽  
pp. 658-666 ◽  
Author(s):  
Ching-Hsiang Chen ◽  
Kuo-Sheng Hung ◽  
Yu-Chu Chung ◽  
Mei-Ling Yeh
Keyword(s):  
Quality Of Life ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
High Frequency ◽  
Standard Care ◽  
Low Frequency ◽  
Control Group ◽  
Subacute Stroke ◽  
Interactive Exercise

Background: Stroke, a medical condition that causes physical disability and mental health problems, impacts negatively on quality of life. Post-stroke rehabilitation is critical to restoring quality of life in these patients. Objectives: This study was designed to evaluate the effect of a mind–body interactive qigong intervention on the physical and mental aspects of quality of life, considering bio-physiological and mental covariates in subacute stroke inpatients. Methods: A randomized controlled trial with repeated measures design was used. A total of 68 participants were recruited from the medical and rehabilitation wards at a teaching hospital in northern Taiwan and then randomly assigned either to the Chan-Chuang qigong group, which received standard care plus a 10-day mind–body interactive exercise program, or to the control group, which received standard care only. Data were collected using the National Institutes of Health Stroke Scale, Hospital Anxiety and Depression Scale, Short Form-12, stroke-related neurologic deficit, muscular strength, heart rate variability and fatigue at three time points: pre-intervention, halfway through the intervention (day 5) and on the final day of the intervention (day 10). Results: The results of the mixed-effect model analysis showed that the qigong group had a significantly higher quality of life score at day 10 ( p<0.05) than the control group. Among the covariates, neurologic deficit ( p=0.04), muscle strength ( p=0.04), low frequency to high frequency ratio ( p=0.02) and anxiety ( p=0.04) were significantly associated with changes in quality of life. Conversely, heart rate, heart rate variability (standard deviation of normal-to-normal intervals, low frequency and high frequency), fatigue and depression were not significantly associated with change in quality of life ( p >0.05). Conclusions: This study supports the potential benefits of a 10-day mind–body interactive exercise (Chan-Chuang qigong) program for subacute stroke inpatients and provides information that may be useful in planning adjunctive rehabilitative care for stroke inpatients.

The relationship between chemotherapy-induced peripheral neuropathy and heart rate variability.

2020 ◽  
Vol 38 (4_suppl) ◽  
pp. 820-820
Author(s):  
Aelee Jang ◽  
Dong Uk Kim
Keyword(s):  
Quality Of Life ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Peripheral Neuropathy ◽  
Frequency Band ◽  
High Frequency ◽  
Chemotherapeutic Agents ◽  
High Frequency Band ◽  
The Relationship

820 Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a common complication related to chemotherapeutic agents and dose accumulation. Initial symptoms are known to be sensory including numbness and pain whereas autonomic symptoms are the latest. Autonomic dysfunction is related to heart rate variability (HRV) change which may precede the symptoms. But, the relationship between CIPN and heart rate variability is not fully evaluated. Therefore, we aimed to evaluate the HRV with CIPN-related questionnaires in patients underwent chemotherapy. Methods: Fifty-five patients with gastrointestinal cancers were enrolled in this cross-sectional cohort study. Patients have received chemotherapeutic agents such as paclitaxel, cisplatin, and oxaliplatin. CIPN was diagnosed using National Cancer Institute Common Toxicity Criteria for Adverse Event (NCI-CTCAE version 4.03). We evaluated the quality of life, CIPN symptom scale, and HRV. Results: Forty-two patients were male (76.4%) and mean age was 63.2 years old. Thirty-nine patients (71.0%) had CIPN of more than grade I according to NCI-CTCAE. Patients with CIPN represented lower physical and role functions. The standard deviation of all normal R-R intervals (SDNN) was decreased in the CIPN group. Parasympathetic tone (high frequency band) were decreased, but sympathetic activity (low frequency band/high frequency band) were increased in CIPN. Conclusions: CIPN affected the quality of life in gastrointestinal cancer patients underwent chemotherapy. HRV was related to CIPN. Further study may be needed to check the feasibility of HRV as early biomarkers for detecting CIPN. [Table: see text]

scholarly journals Effect of moderate physical exercises on the relationship of variability of the heart rhythm with the level of blood pressure and hemodynamic functions in women with essential hypertension

2020 ◽  
pp. 64-73
Author(s):  
Б.И. Кузник ◽  
Ю.Н. Смоляков ◽  
Е.С. Гусева ◽  
С.О. Давыдов ◽  
И.В. Файн
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Blood Flow ◽  
Heart Rate Variability ◽  
Essential Hypertension ◽  
High Frequency ◽  
Low Frequency ◽  
Mean Square ◽  
Positive Correlations ◽  
The Relationship

Цель исследования - выявление взаимосвязи между показателями вариабельности сердечного ритма (ВСР), кровяным давлением и гемодинамическими функциями у женщин, страдающих гипертонической болезнью (ГБ) и находящихся на медикаментозной терапии (ГБ-1), либо в дополнение к этому, проходящих регулярные курсы кинезитерапии (ГБ-2). Методика. Наблюдения проведены на 72 женщинах, страдающих артериальной гипертензией II стадии. В группу ГБ-1 вошли 37 женщин с ГБ, находящихся на медикаментозной терапии, в группу ГБ-2 - 35 женщин с ГБ, которые, помимо медикаментозной терапии, регулярно проходили на протяжении 2-3 лет по 3-4 полуторамесячных курса кинезитерапии (управляемые умеренные физические нагрузки). Для изучения гемодинамики был использован датчик динамического рассеяния света (miniature Dynamic Light Scattering - mDLS) от Elfi-Tech (Rehovot, Israel), измеряющий сигналы, инициированные кожным кровотоком, и использующий методику разложения сигнала на частотные компоненты, связанные с разными гемодинамическими источниками. Из пульсовой компоненты mDLS сигнала извлекалась информация о вариабельности RR-интервалов и рассчитывались индикаторы вариабельности сердечного ритма. Введен показатель «гемодинамический индекс» (Hemodynamic Index - HI). Зависимость HI от скорости сдвига интерпретируется путем сопоставления каждой полосе частот определенной скорости сдвига (HI1 - низкочастотный, HI2 - промежуточный, HI3 - высокочастотный). Использованы следующие относительные (RHI, Relative Hemodynamic Index) и осцилляторные (OHI, Oscillatory Hemodynamic Indexes) гемодинамические индексы: нейрологический (NEUR), Майера (MAYER), дыхательный (RESP) и пульсовой (PULSE). ВСР показатели включали: HR (Heart Rate), PWR (Power) - общую мощность колебаний, LF (Low Frequency), HF (High Frequency), SDNN (Standard Deviation of the Normal-to-Normal), RMSSD (Root Mean Square of the Successive Differences), а также индексы: CVI (Cardiac Vagal Index) и CSI (Cardiac Sympathetic Index). Результаты. У женщин, находящихся исключительно на медикаментозной терапии (ГБ-1), выявляются отрицательные взаимосвязи LF и LF/HF с систолическим, средним и пульсовым давлением. При ГБ-2 проявляются отрицательные связи PWR, LF, HF с пульсовым давлением. При ГБ-1 обнаружены положительные взаимосвязи между HR и гемодинамическими индексами HI1, RHI2 и отрицательная взаимосвязь с RHI3, а также между RMSSD и RHI3 и между HF и HI1/HI3. У пациенток ГБ-2 обнаружена отрицательная корреляция SDNN и RHI1, а также PWR и RHI1; положительные взаимосвязи между PWR и HI2, HI3, RHI2, HF и RHI3 и LF/HF с HI1/HI3; отрицательные связи HF c HI1/HI3 и с RHI1, а также между LF/HF и RHI3, CSI и RHI3. У больных ГБ-1 имеются прямые связи между SDNN, PWR, LF, HF, CVI и NEUR_HI1, что свидетельствует о действии этих факторов на эндотелиальный кровоток (HI1). В группе ГБ-2 установлено наличие лишь положительных связей между LF, HF и NEUR_HI3. У больных ГБ-1 на уровень АД влияют все без исключения осцилляторные ритмы, которые могут оказывать как отрицательное (с MAYER_HI1, PULSE_HI2), так и положительное (MAYER_HI2, RESP_HI3) влияние. У больных ГБ-2 взаимосвязи АД с осцилляторными индексами не обнаружены. Заключение. Уменьшение в группе ГБ-2 по сравнению с больными группы ГБ-1 числа факторов, влияющих на АД и гемодинамику, носит более совершенный и благоприятный характер, что и обеспечивает более быструю и устойчивую нормализацию артериального давления. Aim. To study the relationship between heart rate variability (HRV), blood pressure and hemodynamic functions in women with essential hypertension (EH) receiving a drug therapy alone (EH-1) or in combination with regular courses of kinesitherapy (EH-2). Methods. The study included 72 women with EH. The EH-1 group consisted of 37 women with stage II arterial hypertension. The EH-2 group consisted of 35 women with stage II arterial hypertension who underwent 3-4 1.5-month courses of kinesitherapy (controlled moderate physical activity) on a regular basis for 2-3 years. Hemodynamics was studied with a miniature Dynamic Light Scattering (mDLS) sensor from Elfi-Tech (Rehovot, Israel), which measures signals initiated by the skin blood flow by decomposing the signal into frequency components associated with different hemodynamic sources. Information on the RR interval variability was extracted from the pulse component of mDLS signal, and indicators of heart rate variability were calculated. A Hemodynamic Index (HI) was introduced. The HI dependence on shear rate was interpreted by matching each frequency band with a specific shear rate (HI1, low-frequency; HI2, intermediate; HI3, high-frequency). The following relative (RHI, Relative Hemodynamic Index) and oscillatory (OHI, Oscillatory Hemodynamic Indexes) indexes were used: neurological (NEUR), Mayer (MAYER), respiratory (RESP), and pulse (PULSE) ones. The HRV indexes included HR (Heart Rate), PWR (Power, total oscillation power), LF (Low Frequency), HF (High Frequency), SDNN (Standard Deviation of the Normal-to-Normal), RMSSD (Root Mean Square of the Successive Differences). CVI (Cardiac Vagal Index), and CSI (Cardiac Sympathetic Index). Results. In women who were on drug therapy alone (EH-1), negative relationships were found for LF and LF/HF with systolic, mean and pulse pressure. For EH-2, PWR, LF, and HF negatively correlated with pulse pressure. For EH-1, HR positively correlated with the hemodynamic indices HI1 and RHI2 and negatively correlated with RHI3; RMSSD negatively correlated with RHI3; and HF negatively correlated with HI1/HI3. For patients with EH-2, negative correlations were observed for SDNN and RHI1, PWR and RHI1; positive correlations were found between PWR and HI2; HI3, RHI2, HF and RHI3; and between LF/HF and HI1/HI3. HF negatively correlated with HI1/HI3 and with RHI1. LF/HF negatively correlated with RHI3, and CSI negatively correlated with RHI3. In patients with EH-1, SDNN, PWR, LF, HF, CVI, and NEUR_HI1 were directly related, which indicated an effect of these factors on the endothelial blood flow (HI1). In the EH-2 group, only positive correlations were found between LF, HF, and NEUR_HI3. In EH-1 patients, all oscillatory rhythms influenced BP; this influence could be both negative (for MAYER_HI1, PULSE_HI2) and positive (for MAYER_HI2, RESP_HI3). In EH-2 patients, no relationship was found between blood pressure and oscillatory indices. Conclusion. The smaller number of factors influencing blood pressure and hemodynamics in the EH-2 group compared to the EH-1 group was more beneficial and favorable, which ensured faster and steadier normalization of blood pressure.

scholarly journals The relationship between emotion regulation capacity, heart rate variability, and quality of life in individuals with alcohol-related brain damage

2016 ◽  
Vol Volume 9 ◽  
pp. 219-235 ◽  
Author(s):  
Jean-Paul Steinmetz ◽  
Claus Vögele ◽  
Christiane Theisen-Flies ◽  
Carine Federspiel ◽  
Stefan Sütterlin
Keyword(s):  
Quality Of Life ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Emotion Regulation ◽  
Brain Damage ◽  
The Relationship

A-44 Implications of the Heart Rate Variability Power Spectrum on the Relationship between Prenatal Anxiety Exposure and Child Anxiety in 5-Year-Olds

2021 ◽  
Vol 36 (6) ◽  
pp. 1085-1085
Author(s):  
Christine L Ginalis ◽  
Jeenia Zaki ◽  
Ana Cristina Bedoya ◽  
Yoko Nomura
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Power Spectrum ◽  
High Frequency ◽  
Child Anxiety ◽  
Low Frequency ◽  
Maternal Anxiety ◽  
Prenatal Anxiety ◽  
Anxiety Levels ◽  
The Relationship

Abstract Objective To assess the role of the heart rate variability (HRV) in the relationship between prenatal anxiety exposure and subsequent child anxiety levels. Methods A longitudinal study of mother–child dyads (subsample of 89) measured maternal anxiety during the second trimester of pregnancy (self-reported via STAI-S) and subsequent child anxiety (maternal-reported via BASC-3) and baseline autonomic physiological measures (high and low frequency band of HRV power spectrum) at 5-years-old. Mediation analysis was conducted to test whether child high and/or low frequency HRV mediates the relationship between prenatal anxiety and child anxiety. Results Prenatal anxiety predicted child anxiety (β = 0.137, p = 0.004) and high frequency HRV (β = −0.009, p &lt; 0.001), but not low frequency HRV (β = −0.002, p = 0.231). Mediation analysis using bootstrapping procedure revealed that high frequency HRV (β = 0.044, 95% CI [0.007, 0.085]), but not low frequency HRV (β = 0.0117, 95% CI [−0.007, 0.047]), mediated the relationship between prenatal anxiety and child anxiety. After controlling for high frequency HRV, prenatal anxiety was no longer associated with child anxiety (β = 0.0753, p = 0.148). Conclusion Results indicate that in-utero exposure to maternal anxiety influences the child’s high frequency but not low frequency HRV. Importantly, changes in only high frequency HRV from prenatal anxiety is driving the relationship between prenatal anxiety and child anxiety levels, indicating that maternal anxiety during pregnancy affects the development of the autonomic nervous system with long term effects on child emotional regulation. The results suggest that the high frequency portion of the HRV power spectrum should be assessed in a multidimensional model of fetal programming and subsequent mental health risk of the child.

Abstract P399: The Relationship Between Heart Rate Variability and Common Carotid Artery Intima-media Thickness. The ELSA-Brasil

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Rosangela Hoshi ◽  
Paulo A LOTUFO ◽  
Itamar S Santos ◽  
Alessandra C Goulart ◽  
Jose-Geraldo Mill ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Carotid Artery ◽  
Common Carotid Artery ◽  
High Frequency ◽  
Low Frequency ◽  
Intima Media Thickness ◽  
Media Thickness ◽  
The Mean ◽  
The Relationship

Background: Both conditions as a more width common carotid artery intima-media thickness (cIMT), and a low heart rate variability (HRV) have been associated with cardiovascular health-adverse outcomes. Although previous studies have somehow explored the relationship between these markers, they have not credited the influences exerted by factors such as aging, demographics, and lifestyle variables. Aim: to investigate whether cardio autonomic alterations are accompanied or not by subclinical atherosclerosis, in apparently healthy men and women aged 35 to 74 years-old examined at the baseline of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Methods: The Heart Rate Variability was evaluated on 5-min segments of beat-to-beat heart rate recordings using linear time and frequency domain analyses. The c-IMT images were performed using a Toshiba (Aplio XG™) with a 7.5 MHz linear transducer. The c-IMT was measured in the outer wall during three cardiac cycles. The images were analyzed with specific software (MIA™, Coralville, IA). For this study, c-IMT was defined as the average between the mean left and mean right c-IMT values, and it was analyzed as a continuous and categorized variable (P<75 or P >= 75). Multiple linear models using continuous variables and multivariate logistic regression with categorized cIMT and HRV quartiles were performed. Results: Out of 7,201 participants eligible for analyses, 1,685 (23.4%) presented cIM >= 75th percentile. We found significantly reduced HRV variables in subjects with cIMT>=P75 in comparison to those with cIMT<P75: standard deviation of NN interval (SDNN) 33.0 ms vs. 37.0ms( P< 0.001); root of the mean of the sum of the squares of differences between adjacent NN intervals (RMSSD) 22.0 ms vs. 26.0ms (P< 0.001); Low-Frequency 191.0ms 2 vs. 260.0ms 2 ( P< 0.001); High-Frequency 164.0 ms 2 vs. 238.5ms 2 ( P< 0.001). In a crude analysis, an increased Odds Ratio (OR)and 95% Confidence Intervals for cIMT >=P75 was verified within the lowest two quartiles of Low-Frequency:1st quartile, OR = 1.75 (95%CI: 1.39 to 2.19); 2nd quartile, OR= 1.53 (1.25 to 1.87).The same was observed for High-Frequency:1st quartile, OR = 1.94 (1.38 to 2.73); 2nd quartile, OR= 1.60 (1.20 to 2.15). However, those associations did not remain after adjustments for anthropometric and clinical variables for Low-Frequency (1st quartile, OR= 1.08 (0.83 to 1.40); 2nd quartile, OR= 1.22 (0.97 to1.55), and for High Frequency, 1st quartile, OR= 1.16 (0.77 to 1.73); 2nd quartile, OR= 1.17 (0.83 to 1.64). Conclusions: Subjects with cIMT greater or equal to 75th percentile presented lower HRV values. However, no independent relationships were detected between cIMT and HRV after multivariate adjustment, suggesting that they may assess different and complementary domains and provide relevant, useful, and non-redundant information of cardiovascular risk.

scholarly journals Impact of Electroacupuncture Treatment on Quality of Life and Heart Rate Variability in Fibromyalgia Patients

2016 ◽  
Vol 22 (2) ◽  
pp. 216-222 ◽  
Author(s):  
Livia G. Díaz-Toral ◽  
Tania R. Banderas-Dorantes ◽  
José F. Rivas-Vilchis
Keyword(s):  
Quality Of Life ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Short Form ◽  
Fibromyalgia Impact Questionnaire ◽  
Low Frequency ◽  
Related Quality ◽  
Health Related ◽  
Electroacupuncture Treatment

This study examines the effects of electroacupuncture treatment on health-related quality of life and heart rate variability in women with fibromyalgia. Twenty women with fibromyalgia received a 10-week treatment with electroacupuncture. Primary outcome measures were the Fibromyalgia Impact Questionnaire, the Short Form 36 Health Survey Questionnaire, and heart rate variability. Compared with pretreatment, there was a significant improvement in health-related quality of life; electroacupuncture significantly increases low frequency, low frequency/high frequency, and decreases high frequency, all indicating rise in sympathetic tone. Fibromyalgia patients showed a significant ( P < .05) improvement in pain, fatigue, morning tiredness, stiffness, anxiety, and depression on the Fibromyalgia Impact Questionnaire scores; and physical function, physical role, body pain, general health, and vitality scores on the Short Form 36 Health Survey Questionnaire. These changes mainly in mental status scores could be related to a new autonomic balance with sympathetic predominance at the horary of the study.

Therapeutic Affordances of Social Media and Associated Quality of Life Outcomes in Young Adults

2021 ◽  
pp. 089443932110329
Author(s):  
Paul Dodemaide ◽  
Mark Merolli ◽  
Nicole Hill ◽  
Lynette Joubert
Keyword(s):  
Quality Of Life ◽  
Social Media ◽  
Young Adults ◽  
Well Being ◽  
Evidence Base ◽  
Social And Emotional ◽  
Perceived Quality Of Life ◽  
Use Of Social Media ◽  
The Relationship

There is a growing body of literature exploring the general population’s use of social media for assistance in dealing with stigmatized health issues. This study presents novel research examining the relationship between social media use and young adults. It utilizes a therapeutic affordance (TA) framework. Quantitative results from this study are complemented by qualitative data. The relationships between distinct social media and their TA (a–b) are presented to highlight their potential to impact positively on social and emotional well-being outcomes. Evidence includes broad support for “connection,” “narration,” and “collaboration” TAs in this context and the relationship between the use of distinct social media and perceived quality of life (QOL) outcomes (a–c). TA provides an appropriate and valuable theoretical framework which is useful for the development of an evidence-base from the analysis of young adult’s social media usage. An analysis of the association between social media and their QOL outcomes is presented according to the TA relationship pathway (a–c–b). The adoption of a TA framework enables a nuanced analysis of significant associations between specific social media, TA, and improved QOL outcomes. This study demonstrates the significant association between social media and perceived QOL outcomes in young adults.

scholarly journals The Influence ofNrf2on Cardiac Responses to Environmental Stressors

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Reuben Howden ◽  
Eva Gougian ◽  
Marcus Lawrence ◽  
Samantha Cividanes ◽  
Wesley Gladwell ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
High Frequency ◽  
Low Frequency ◽  
Therapeutic Strategies ◽  
Environmental Stressors ◽  
Total Power ◽  
Airborne Pollutants ◽  
Cardiac Responses

Nrf2protects the lung from adverse responses to oxidants, including 100% oxygen (hyperoxia) and airborne pollutants like particulate matter (PM) exposure, but the role ofNrf2on heart rate (HR) and heart rate variability (HRV) responses is not known. We hypothesized that genetic disruption ofNrf2would exacerbate murine HR and HRV responses to severe hyperoxia or moderate PM exposures.Nrf2-/-andNrf2+/+mice were instrumented for continuous ECG recording to calculate HR and HRV (low frequency (LF), high frequency (HF), and total power (TP)). Mice were then either exposed to hyperoxia for up to 72 hrs or aspirated with ultrafine PM (UF-PM). Compared to respective controls, UF-PM induced significantly greater effects on HR (P<0.001) and HF HRV (P<0.001) inNrf2-/-mice compared toNrf2+/+mice.Nrf2-/-mice tolerated hyperoxia significantly less thanNrf2+/+mice (~22 hrs;P<0.001). Reductions in HR, LF, HF, and TP HRV were also significantly greater inNrf2-/-compared toNrf2+/+mice (P<0.01). Results demonstrate thatNrf2deletion increases susceptibility to change in HR and HRV responses to environmental stressors and suggest potential therapeutic strategies to prevent cardiovascular alterations.

scholarly journals Effect of Acupuncture on Heart Rate Variability: A Systematic Review

2014 ◽  
Vol 2014 ◽  
pp. 1-19 ◽  
Author(s):  
Joanne W. Y. Chung ◽  
Vincent C. M. Yan ◽  
Hongwei Zhang
Keyword(s):  
Systematic Review ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
High Frequency ◽  
Healthy Subjects ◽  
Keyword Search ◽  
Data Extraction ◽  
Meta Analysis ◽  
Low Frequency ◽  
Control Group

Aim.To summarize all relevant trials and critically evaluate the effect of acupuncture on heart rate variability (HRV).Method.This was a systematic review with meta-analysis. Keyword search was conducted in 7 databases for randomized controlled trials (RCTs). Data extraction and risk of bias were done.Results.Fourteen included studies showed a decreasing effect of acupuncture on low frequency (LF) and low frequency to high frequency ratio (LF/HF ratio) of HRV for nonhealthy subjects and on normalized low frequency (LF norm) for healthy subjects. The overall effect was in favour of the sham/control group for high frequency (HF) in nonhealthy subjects and for normalized high frequency (HF norm) in healthy subjects. Significant decreasing effect on HF and LF/HF ratio of HRV when acupuncture was performed on ST36 among healthy subjects and PC6 among both healthy and nonhealthy subjects, respectively.Discussion.This study partially supports the possible effect of acupuncture in modulating the LF of HRV in both healthy and nonhealthy subjects, while previous review reported that acupuncture did not have any convincing effect on HRV in healthy subjects. More published work is needed in this area to determine if HRV can be an indicator of the therapeutic effect of acupuncture.

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