International Efforts in Nanoinformatics Research Applied to Nanomedicine

Summary Background: Nanomedicine and nanoinformatics are novel disciplines facing substantial challenges. Since nanomedicine involves complex and massive data analysis and management, a new discipline named nanoinformatics is now emerging to provide the vision and the informatics methods and tools needed forsuch purposes. Methods from biomedical informatics may prove applicable with some adaptation despite nanomedicine involving different biophysical and biochemical characteristics of nanomaterials and corresponding differences in information complexity. Objectives: We analyze recent initiatives and opportunities for research in nanomedicine and nanoinformatics as well as the previous experience of the authors, particularly in the context of a European project named ACTION-Grid. In this project the authors aimed to create a collaborative environment in biomedical and nanomedical research among countries in Europe, Western Balkans, Latin America, North Africa and the USA. Methods: We review and analyze the rationale and scientific issues behind the new fields of nanomedicine and nanoinformatics. Such a review is linked to actual research projects and achievements of the authors within their groups. Results: The work of the authors at the intersection between these two areas is presented. We also analyze several research initiatives that have recently emerged in the EU and USA context and highlight some ideas for future action at the international level. Conclusions: Nanoinformatics aims to build new bridges between medicine, nanotechnology and informatics, allowing the application of computational methods in the nano-related areas. Opportunities for world-wide collaboration are already emerging and will be influential in advancing the field.

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The integrated assessment of RES cooperation between the EU and its neighbours

International Journal of Energy Sector Management ◽

10.1108/ijesm-01-2015-0004 ◽

2016 ◽

Vol 10 (3) ◽

pp. 427-447 ◽

Cited By ~ 1

Author(s):

Marijke Welisch ◽

Gustav Resch ◽

André Ortner

Keyword(s):

Renewable Energy ◽

North Africa ◽

Renewable Energy Sources ◽

The European Union ◽

Western Balkans ◽

Member States ◽

Content Type ◽

Eu Member States ◽

Good Resource ◽

The Eu

Purpose The purpose of the paper is to provide estimation results for feasibility of renewable energy source (RES) deployment in Turkey, the Western Balkans and North Africa. From these results, the potential for cooperation in renewables production between the countries and the European Union (EU) is assessed and evaluated, in a mid- (2030) and long-term (up to 2040) perspective. Design/methodology/approach The authors focus on the quantitative assessments undertaken on the extent to which RES cooperation can create mutual benefits, identifying costs and benefits for both sides, but in particular with respect to RES target achievement (2020 and 2030) at EU level. The potentials for RES generation in Turkey, North Africa and the Western Balkans are calculated under different policy pathways, taking into account different levels of economic and non-economic barriers that could occur. Findings Overall, the authors found that increasing RES deployment in the three analysed regions and initiating or intensifying cooperation with EU28 Member States leads to mutual benefits. Concretely, these benefits become apparent in terms of the EU Member States importing renewable energy sources for electricity with a good resource quality and adding on to their targets for RES deployment. At the same time, substantial savings occur for the EU, in turn leading to income and investments in the cooperating regions. Originality/value The assessment underlying this paper is the first of its kind to the authors’ knowledge that opens up the geographical spread in comparison to merely assessing cooperation between Europe and the Middle East and North Africa. Furthermore, the multitude of policy parameters analysed provides detailed and robust insights concerning a broad variety of different possible scenarios.

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Sanctions of the USA and the Policy of Bank of Russia:double Blow to the National Economy

Voprosy Ekonomiki ◽

10.32609/0042-8736-2014-9-13-29 ◽

2014 ◽

pp. 13-29 ◽

Cited By ~ 13

Author(s):

S. Glazyev

Keyword(s):

National Security ◽

Economic Sanctions ◽

Capital Flight ◽

Practical Advice ◽

The Us ◽

Monetary Authorities ◽

The Usa ◽

Simultaneous Adoption ◽

The Eu

This article examines fundamental questions of monetary policy in the context of challenges to the national security of Russia in connection with the imposition of economic sanctions by the US and the EU. It is proved that the policy of the Russian monetary authorities, particularly the Central Bank, artificially limiting the money supply in the domestic market and pandering to the export of capital, compounds the effects of economic sanctions and plunges the economy into depression. The article presents practical advice on the transition from external to domestic sources of long-term credit with the simultaneous adoption of measures to prevent capital flight.

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Assessment of Poland's Economic Policy During te Crisis

Olsztyn Economic Journal ◽

10.31648/oej.3230 ◽

2013 ◽

Vol 8 (3) ◽

pp. 195-210

Author(s):

Stefan Krajewski

Keyword(s):

Economic Policy ◽

Pension System ◽

Fiscal Sustainability ◽

Economic Policies ◽

Role Of The State ◽

The Usa ◽

Reducing Costs ◽

Polish Economy ◽

Favorable Conditions ◽

The Eu

The rapid weakening of economic activity, covering most states in the world, gives rise to a lively discussion on the choice of methods to tackle the crisis, the legitimacy and effectiveness of various economic policies, the role of the state and the scope of its intervention in the economy. The paper evaluates the Polish economic policy in recent years. This refers to the situation prevailing in the EU and the USA. I conclude that the Polish economy during the crisis remained relatively stable, without having to provide the emergency aid from the outside. The development of such a situation has been affected by different reasons, including: - The benefits of the so-called "backwardness rent", which resulted, among others, in the inflow of EU funds (Poland was in 2007-2013 and in will be in 2014-2020 the biggest beneficiary of the EU budget); - The effects of decisions on changes in the tax and social security, taken for political reasons (before the crisis); - The controversial withdrawal from the funded pension system, reducing the budget deficit and public debt; - The prudent monetary policy and anti-inflation policy pursued over many years. Actions taken in Poland are primarily focused on reducing costs, which differs quite significantly from the economic policy dominant in the U.S. and the "old" EU countries which generally pursue expansionary fiscal policy and a policy of cheap money. Polish solution facilitates the achievement of short-term fiscal sustainability, but does not create favorable conditions for the development in the long-term (insufficient investment, petrification of economic structure, lack of innovation).

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Naldemedine: Peripherally Acting Opioid Receptor Antagonist for Treating Opioid-induced Adverse Effects

Current Topics in Medicinal Chemistry ◽

10.2174/1568026620666200710105953 ◽

2020 ◽

Vol 20 (31) ◽

pp. 2830-2842

Author(s):

Masanao Inagaki ◽

Toshiyuki Kanemasa ◽

Takaaki Yokota

Keyword(s):

Adverse Effects ◽

Adverse Events ◽

Severe Pain ◽

Lead Compound ◽

Inhibitory Effects ◽

Pharmacokinetic Profiles ◽

Structure Activity ◽

The Usa ◽

Relationship Study ◽

The Eu

Opioids are widely used for pain management in moderate-to-severe pain. However, opioids are associated with adverse events, such as constipation and emesis/vomiting. To reduce these undesired effects, a structure–activity relationship study of morphinan derivatives was conducted, and a promising lead compound with inhibitory effects on opioid receptors was obtained. Further improvement in the potency and pharmacokinetic profiles of the lead compound led to the discovery of naldemedine, which showed anti-constipation and anti-emetic effects against these adverse events that were induced by morphine without influencing morphine’s analgesic effect. Naldemedine was launched in Japan and the USA in 2017 and in the EU in 2019, for treating opioid-induced constipation.

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The Western Balkans on the Way to the EU: Revisiting EU Conditionality

10.1007/16247_2020_16 ◽

2021 ◽

Author(s):

Agne Limante

Keyword(s):

Western Balkans ◽

The Eu ◽

The Way

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Factors affecting fluctuations in China’s aquatic product exports to Japan, the USA, South Korea, Southeast Asia, and the EU

Aquaculture International ◽

10.1007/s10499-021-00761-y ◽

2021 ◽

Author(s):

Miao Miao ◽

Huang Liu ◽

Jun Chen

Keyword(s):

South Korea ◽

Southeast Asia ◽

Factors Affecting ◽

Aquatic Product ◽

The Usa ◽

The Eu

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Events in Northern Africa and Middle East: Causes and Consequences

World Economy and International Relations ◽

10.20542/0131-2227-2011-7-11-25 ◽

2011 ◽

pp. 11-25

Author(s):

I. Labinskaya

Keyword(s):

Middle East ◽

North Africa ◽

Large Scale ◽

Arab Countries ◽

Northern Africa ◽

External Factors ◽

Wide Range ◽

The Usa ◽

Oriental Studies

Political developments in North Africa and the Middle East that have begun in January 2011 are gaining strength and involve an increasing number of Arab countries. The participants of the Roundtable – experts from IMEMO, Institute of Oriental Studies (RAS), Institute of the USA and Canada (RAS) and Mrs. E. Suponina from “Moscow News” newspaper analyzed a wide range of issues associated with these events. Among them are: 1) the reasons for such a large-scale explosion, 2) the nature of the discussed developments (revolutions, riots?) and who are the subjects of the current “Arab drama”, 3) the role of Islam and political Islamism, 4) the role of external factors.

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Environmentally friendly and socially responsible investment in and by occupational pension funds in the USA and in the EU

European Journal of Social Security ◽

10.1177/13882627211026930 ◽

2021 ◽

pp. 138826272110269

Author(s):

Lauren Daniels ◽

Yves Stevens ◽

David Pratt

Keyword(s):

Financial Performance ◽

Investment Decision ◽

Pension Funds ◽

Socially Responsible Investment ◽

Occupational Pension ◽

Socially Responsible ◽

Responsible Investment ◽

Occupational Pensions ◽

The Usa ◽

The Eu

Worldwide pension funds, in their capacity as large institutional investors, are under increasing pressure to take social and environmental considerations into account in their investment decision-making process. The concepts Socially Responsible Investment (SRI) and Environmental Social Governance (ESG) are indeed ubiquitous in the current investment and pension community. This article aims to provide some insight into the conceptual relationship between SRI and ESG and its legal implications for the investment behaviour of private pension funds in the USA and the EU. Hence, the first part of the article gives some background to the distinct concepts of SRI and ESG. This leads to the finding that SRI goes one step further than ESG by prioritising moral or ethical considerations that may not be material to an investment’s financial performance, whereas ESG functions as a guideline to enhance financial performance. The second part analyses the legal possibilities and constraints for responsible investment in American occupational pensions and the third part does the same for European occupational pensions. The article concludes with a summary and comparative overview of the American and European lessons.

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