scholarly journals Effectiveness of Preoperative Chlorhexidine Mouthwash on Pain After Lower Posterior Teeth Removal: A Randomized, Double-Blind Clinical Trial

2020 ◽  
Vol 12 (4) ◽  
pp. 112-119
Author(s):  
Abbas Haghighat ◽  
Shaqayeq Ramezanzade
Keyword(s):  
Control Group ◽  
Placebo Control ◽  
Study Group ◽  
Mouth Rinse ◽  
Pain Level ◽  
Double Blind ◽  
Posterior Teeth ◽  
Post Operative Pain ◽  
Double Blind Clinical Trial ◽  
Significant Difference

Background: Pain is one of the most common complications after tooth extraction and pain control is a crucial part of the procedure. The purpose of this study was to investigate the influence of 0.2% (w/v) chlorhexidine (CHX) gluconate mouth rinse on the severity of post-extraction pain. Methods: A prospective, randomized, double-blind trial was conducted among 170 subjects. Subjects were instructed to rinse with 15 mL of CHX mouth rinse (study group) or placebo (control group) 0.5 to 1 hour before extraction. Post-operative pain was evaluated considering the number of taken rescue analgesics and using a visual analog scale (VAS) that each case completed 6, 12, 24, and 48 hours after the surgery. The Mann-Whitney U test was performed in this regard. Results: There were no significant differences between the two groups regarding demographic variables (P>0.05). The preoperative use of CHX mouth rinse showed a better performance in mitigating the perceived pain. A significant difference in the pain level (P=0.001) was found only at the 6th hour postoperatively although there was no significant difference in the pain level between the two groups (P>0.05) at all other times (12th, 24th, 48th hours). The total number of analgesics that were taken by the study group was significantly lower compared to the control group (P=0.042). Conclusions: The preoperative CHX mouth rinse could be a beneficial choice for reducing pain after simple tooth extractions.

scholarly journals Periarticular Injection with Bupivacaine for Postoperative Pain Control in Total Knee Replacement: A Prospective Randomized Double-Blind Controlled Trial

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Varah Yuenyongviwat ◽  
Chaturong Pornrattanamaneewong ◽  
Thitima Chinachoti ◽  
Keerati Chareancholvanich
Keyword(s):  
Pain Control ◽  
Controlled Trial ◽  
Ease Of Use ◽  
Morphine Consumption ◽  
Controlled Study ◽  
Control Group ◽  
Double Blind ◽  
Periarticular Injection ◽  
Post Operative Pain ◽  
Significant Difference

Background. Local periarticular injection with bupivacaine alone in TKA has not been studied. Thus, we aimed to examine the effectiveness of local periarticular injection with bupivacaine for post-operative pain control in TKA.Method. Sixty patients undergoing TKA by a single surgeon were randomly assigned into two groups in a double-blind, placebo-controlled study. In the injection group, patients received periarticular injections with 0.25% bupivacaine before wound closure; in the control group, patients received a 0.9% normal saline injection. Both groups received the same anesthetic procedure, post-operative pain control, and rehabilitation protocol.Results. There was a significant reduction in post-operative morphine consumption in the first six hours after the operation (mean 0.9 mg and 2.43 mg,P=0.01), but there was no significant difference in post-operative morphine consumption between six hours and ninety-six hours after the operation, visual analogue scale (VAS) score, morphine side effects during the first 96 hours, length of hospital stay, or complications from morphine consumption.Conclusion. Local periarticular injection with bupivacaine alone before wound closer was shown to be an effective method to improve pain control after TKA with a few complications and ease of use.

scholarly journals An investigation into the effect of evening primrose in dilatation of cervix and pain during and after hysterosalpingography

2019 ◽  
Vol 12 (3) ◽  
pp. 284-289
Author(s):  
Shahrzad Shahnam Nia ◽  
◽  
Fatemeh Safi ◽  
Maryam Shoukrpour ◽  
Alireza Kamali ◽  
...  
Keyword(s):  
Contrast Medium ◽  
Analogue Scale ◽  
Cervical Length ◽  
Diagnostic Methods ◽  
Control Group ◽  
Double Blind ◽  
Evening Primrose ◽  
Double Blind Clinical Trial ◽  
Significant Difference ◽  
Contrast Medium Injection

Hysterosalpingography is one of the essential diagnostic methods for examining women who have difficulty becoming pregnant. This procedure is somehow invasive and is associated with numerous complications such as allergic sensitivity, pain, abdominal cramps and shock. Therefore, this study aimed to investigate the effect of evening primrose on cervical length and pain during and after hysterosalpingography. In this double-blind clinical trial, 66 candidates for hysterosalpingography were randomly divided into two groups. A group received 1000 mg of evening primrose orally for two days prior to hysterosalpingography, while the control group received a placebo drug similar in size to evening primrose three days prior to hysterosalpingography. The pain level was recorded based on the Visual Analogue Scale (VAS), during tenaculum placement but also immediately and four hours after hysterosalpingography. Finally, the data were analyzed using SPSS (version 20). There was a significant difference between the two groups in terms of pain during insertion of speculum and injection of the contrast medium (p <0.05). Less pain was reported in the evening primrose group compared to placebo. There was no significant difference between the two groups in terms of the length and diameter of the cervix (p <0.05). Given the fact that it is a medicinal plant with no complications and can reduce pain during speculum insertion and during contrast medium injection, evening primrose seems to be a good drug for managing pain during hysterosalpingography.

scholarly journals Effect of designed nursing guidelines on acute anal fissure treatment outcomes

2018 ◽  
Vol 8 (10) ◽  
pp. 1
Author(s):  
Esmat Sayed Abd-Elmaged ◽  
Amna Abdallh Desoky ◽  
Tarik Abd-Elazem Abd-Elrahem
Keyword(s):  
Wound Healing ◽  
Anal Fissure ◽  
General Surgery ◽  
Rating Scale ◽  
University Hospital ◽  
Control Group ◽  
Study Group ◽  
Pain Level ◽  
Significant Difference ◽  
Nursing Guidelines

Objective: Anal fissure is a common problem through the world, it causes considerable morbidity. The aim of the study was to evaluate the effect of designed nursing guidelines on acute anal fissure treatment outcomes.Methods: Research design: Quasi-experimental design. Setting: General Surgery Wards and Outpatient Clinics of General Surgery at Assiut University Hospital. Sample: A purposive sample of 60 male and female adult patients diagnosed of having acute anal fissure. Patients were equally divided on random basis into two equal groups (study and control) 30 patients for each. Tools: Tool I-Patient assessment sheet. Tool II-Numeric Pain Rating Scale. Tool III-Bates-Jensen Wound Assessment Tool.Results: No statistically significant difference was found between the study and the control groups as regard demographic data. There was a statistically significant improvement in the pain level and wound healing among the study group (1.63 ± 2.08 and 11.93 ± 4.5 respectively) than in the control group (2.87 ± 2.33 and 14.43 ± 4.29 respectively). Also, there was a high statistically significant improvement in the level of knowledge of the study group than their level before applying the guidelines (p < .001).Conclusions: Designed nursing guidelines had a statistically significant effect on improving patients' knowledge, pain level, and wound healing among the study group patients than among the control group ones with acute anal fissure. Recommendations: Patients teaching should be an integral part of the nurses' duty in all hospitals. Further studies on larger sample from different geographical areas in Egypt to generalize the results.

scholarly journals Effect of SPIKES-based Education by Role Playing and Multimedia Approaches on Breaking Bad News Skills in Midwifery Students (a Comparison)

2017 ◽  
Vol 34 (2) ◽  
pp. 137-146
Author(s):  
Nasrin Baghdari ◽  
Mostafa Rad ◽  
Marzie Torkmannejad Sabzevari
Keyword(s):  
Educational Intervention ◽  
Reliability And Validity ◽  
Role Playing ◽  
Bad News ◽  
Control Group ◽  
Double Blind ◽  
Double Blind Clinical Trial ◽  
Significant Difference ◽  
Before And After ◽  
Delivering Bad News

Summary Due to the diversity of midwives’ responsibilities, the skill to deliver bad news is a vital need, and therefore the teaching approach in this matter is of utmost importance. Thus, this study has been conducted with the purpose of comparing the effect of SPIKES-based education of skills needed for delivering bad news, using two different approaches of role playing and multimedia in midwifery students. This double-blind clinical trial was done on 90 midwifery students who were randomly assigned to three separate groups. Students’ skill in delivering bad news was recorded through a specific checklist before and after the educational intervention. The reliability and validity of this skill evaluation checklist was assessed and confirmed. The final data were analyzed using SPSS software. After educational intervention, role playing and multimedia groups have gained more skills compared to their previous conditions as well as the control group. The skill of delivering bad news did not show a significant difference in role playing and multimedia groups after intervention. The results showed that teaching the skills of delivering bad news using multimedia approach which was held as distance learning course would rival active educational methods such as role playing. Thus, it could be a suitable replacement for role playing methods in increasing the skill needed for delivering bad news.

scholarly journals Clinical effect of a herbal dentifrice on the control of plaque and gingivitis: a double-blind study

2003 ◽  
Vol 17 (4) ◽  
pp. 314-318 ◽  
Author(s):  
Claudio Mendes Pannuti ◽  
Joyce Pereira de Mattos ◽  
Paula Nini Ranoya ◽  
Alberto Martins de Jesus ◽  
Roberto Fraga Moreira Lotufo ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Clinical Effect ◽  
Test Group ◽  
Control Group ◽  
Double Blind Study ◽  
Gingival Index ◽  
Control Groups ◽  
Double Blind ◽  
Double Blind Clinical Trial ◽  
Significant Difference

The aim of this randomized, double-blind clinical trial was to evaluate the effect of the Paradontax dentifrice on the reduction of plaque and gingivitis. Subjects were randomly allocated into either the test group (n = 15, Paradontax) or the control group (n = 15, standard dentifrice with fluoride). Plaque levels were measured using the Turesky modification of the Quigley & Hein Plaque Index (PI), and gingivitis was evaluated with the Gingival Index (GI). Subjects were asked to brush their teeth with the allocated dentifrice, three times a day, for 21 days. There was no significant difference between groups in relation to the PI and GI medians, at baseline and at the end of the 21-day period. There was no significant reduction in PI in either the test or control groups. There was a significant decrease in GI in the test group. The authors concluded that there was no difference between the dentifrices in the reduction of plaque and gingivitis.

scholarly journals The effects of pulsatile flushing on phlebitis and peripheral intravenous catheters patency

2020 ◽  
pp. 16-25
Keyword(s):  
Clinical Setting ◽  
Intervention Group ◽  
Practical Method ◽  
Control Group ◽  
Control Groups ◽  
Double Blind ◽  
Double Blind Clinical Trial ◽  
Significant Difference ◽  
And Control ◽  
Intravenous Catheters

Background and Aim: Thrombophlebitis is considered as a major cause of peripheral intravenous catheters (PICs) failure. The flushing technique in the laboratory has been effective in clearing the catheter duct, but its effectiveness in the clinical setting is unknown, therefore, the aim of this study was to determine the effect of pulsatile flushing on phlebitis, type, and duration of PICs patency in patients. Materials and Methods: In this double-blind clinical trial, 71 patients admitted to the inpatient and surgical wards of Imam Khomeini Esfarayen Hospital were randomly assigned to the intervention and control groups after sampling by available methods. In the intervention group, the flushing technique was performed by injecting 1 ml of the normal saline solution for one second, then interrupting less than one second and repeating the injection and interrupting until the end of 5 ml of the solution. The Consequences of this study were phlebitis, duration, and type of PICs patency, which were evaluated every 12 hours by using Jackson's phlebitis instrument and direct observation of the catheter. Results: The incidence of phlebitis in the intervention group was lower than the control group (P<0.001). In addition, two groups had a statistically significant difference in the type of PICs (P<0.001). The median duration of PICs patency in the intervention group was significantly higher than the control group (P<0.001). Conclusion: Pulsatile flushing is an effective technique to increase longevity of PICs and recommended as a practical method in clinical setting.

scholarly journals A comparative prospective randomised controlled study for mesh fixation by cyanoacrylate glue versus prolene sutures in patients undergoing Lichtenstein hernioplasty

2019 ◽  
Vol 7 (1) ◽  
pp. 83
Author(s):  
Dheer S. Kalwaniya ◽  
Satya V. Arya ◽  
Sumedha Gupta ◽  
Manigandan Kuppuswamy ◽  
Jaspreet S. Bajwa ◽  
...  
Keyword(s):  
Inguinal Hernia ◽  
Mesh Fixation ◽  
Operating Time ◽  
Control Group ◽  
P Value ◽  
Study Group ◽  
Cyanoacrylate Glue ◽  
Post Operative Pain ◽  
Significant Difference

Background: Inguinal hernia repair is one of the most commonly performed procedures by general surgeons. Cyanoacrylate is the generic name for a family of fast acting adhesives. The aim of the present study done in Department of General Surgery, Safdarjung Hospital, New Delhi was to compare the newer emerging technique of mesh fixation.Methods: A total of sixty patients were included in the present study and were allotted in case and control group randomly by sealed envelope technique. In case (study) group, all the patients underwent mesh fixation by cyanoacrylate glue and in control group, by prolene 3-0 sutures.Results: Most frequency in age group 31-40 yrs, males:females ratio >1 and right sided inguinal hernia was more common. Bi-lateral hernia was common in elderly. Indirect: direct ratio 4.5:1. Operating time period for the patients of the case (study) group is less than control group. P value of post-operative pain in immediate post-operative period (day 1 and 2) and POD 30, 60 and 90 was not of clinical significance whereas the p-value on 6,120,150 and 180 post op day was of clinical significance. In our study, there was a case of incidental observation: a) reaction due to use of cyanoacrylate glue, b) rejection of mesh for which mesh had to be removed.Conclusions: There is no statistically significant difference between mesh fixation with cyanoacrylate glue and mesh fixation by prolene suture techniques in immediate post-operative pain. Statistically significant difference favoring mesh fixation by cyanoacrylate glue technique was seen with respect to operating time and post-operative groin pain with increasing post-operative duration.

scholarly journals Therapeutic Effectiveness of Galphimia glauca in Young People with Social Anxiety Disorder: A Pilot Study

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Ofelia Romero-Cerecero ◽  
Ana Laura Islas-Garduño ◽  
Alejandro Zamilpa ◽  
Ma. Dolores Pérez-García ◽  
Jaime Tortoriello
Keyword(s):  
Anxiety Disorder ◽  
Social Anxiety ◽  
Social Anxiety Disorder ◽  
Control Group ◽  
Efficacy And Safety ◽  
Double Blind ◽  
A Value ◽  
Double Blind Clinical Trial ◽  
End Of Treatment ◽  
Significant Difference

Social anxiety is one of the most common disorders found in the population attending the first level of health care. Galphimia glauca has been used for many years in Mexican traditional medicine to treat “nervous disorders”. A standardized extract of this species has been evaluated in clinical studies that have proven its efficacy and safety in patients with generalized anxiety disorder. In this work, a double-blind clinical trial was carried out, using sertraline as a control. Patients from both sexes (18 to 35 years old) with moderate or severe social anxiety were included. Experimental group was treated daily (orally), for 10 weeks, with an extract from G. glauca containing 0.374 mg/dose of Galphimine-B (G-B, active compound). Patients in the control group were given sertraline (50 mg) in the same conditions. All patients were evaluated every two weeks. Another assessment was done one month after the end of the administration period. A total of 34 patients was included, 17 in each group. Women were predominant, and the mean age was 25 ± 4.7 years. In patients who received the G. glauca standardized extract, a significant reduction in anxiety was observed, with a value (in the Brief Social Phobia Scale) of 41.1±10.3 points at the start and 11.2±5.6 points at the end of treatment, while patients treated with sertraline had a value of 37.7±7.3 points at the beginning and 11.1±5.2 points at the end. No significant difference was observed between the treated groups. In a similar way, the health scale showed a gradual and continuous improvement in each of the five evaluations. In conclusion, the 10-week oral administration of G. glauca standardized extract showed efficacy and safety in patients with social anxiety disorder, without showing a significant difference from patients treated with sertraline.

scholarly journals Clinical Effect of a Mouth Rinse containing Ocimum gratissimum on Plaque and Gingivitis Control

2011 ◽  
Vol 12 (5) ◽  
pp. 350-355 ◽  
Author(s):  
Sérgio Luís da Silva Pereira ◽  
José Weslley Gonçalves de Oliveira ◽  
Keyles Karla Sá Vieira Ângelo ◽  
Ângela Maria Alves da Costa ◽  
Flávio Costa
Keyword(s):  
Clinical Effect ◽  
Treatment Options ◽  
Mouth Rinse ◽  
Oral Diseases ◽  
Double Blind ◽  
Ocimum Gratissimum ◽  
Natural Agents ◽  
Double Blind Clinical Trial ◽  
Significant Difference ◽  
Chemotherapeutic Treatment

ABSTRACT Aim The effect of Ocimum gratissimum (Og) on the reduction of dental plaque and gingivitis was evaluated in a randomized, parallel and double-blind clinical trial. Results There was a significant reduction on plaque and gingivitis in tests groups (p < 0.05), but no statistically significant difference was observed among them (p > 0.05). Conclusion Mouth rinse containing Og was effective as antiplaque and antigingivitis agent, in a similar manner that chlorhexidine digluconate. Clinical significance Research in treatment of chronic oral diseases using natural agents must be encouraged to verify which would be a useful addition to the current range of chemotherapeutic treatment options. How to cite this article da Silva Pereira SL, de Oliveira JWG Ângelo KKSV, da Costa ÂMA, Costa F. Clinical Effect of a Mouth Rinse containing Ocimum gratissimum on Plaque and Gingivitis Control. J Contemp Dent Pract 2011;12(5):350-355.

scholarly journals Effect of Neem containing Toothpaste on Plaque and Gingivitis—A Randomized Double Blind Clinical Trial

2015 ◽  
Vol 16 (11) ◽  
pp. 880-883 ◽  
Author(s):  
S Supreetha ◽  
KN Abhishek ◽  
S Nubesh Khan ◽  
KH Chaithanya ◽  
Nishad Abdul
Keyword(s):  
Clinical Trial ◽  
Oral Hygiene ◽  
Dental Students ◽  
T Test ◽  
Control Group ◽  
First Year ◽  
Double Blind ◽  
Double Blind Clinical Trial ◽  
Significant Difference ◽  
And Control

ABSTRACT Aim The present study was designed to assess the effect of toothpaste containing neem on plaque and gingivitis. Materials and methods Randomized, double blind clinical trial was designed. Thirty first year dental students volunteered to participate in the study. Neem containing tooth paste was used as an intervention. Clinical examination was carried out using Silness and Loe plaque index (PI) and Loe and Silness gingival index (GI). Independent t-test and paired t-test was used for the intergroup and the intragroup comparison. Results Out of 30 participants, 22 (73.3%) were females and eight (26.7%) were males. A statistically significant difference was found between the test and control group after intervention with respect to the PI and GI. Conclusion Neem containing toothpaste can be used as an adjunct for maintenance of oral hygiene. Clinical significance Regular brushing with neem toothpaste might act as an adjunct to maintenance of good oral hygiene, and thus improve oral health. How to cite this article Abhishek KN, Supreetha S, Sam G, Khan SN, Chaithanya KH, Abdul N. Effect of Neem containing Toothpaste on Plaque and Gingivitis—A Randomized Double Blind Clinical Trial. J Contemp Dent Pract 2015;16(11):880-883.

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