Psychophysiological Characteristics of Aggression Associated with Depression before and after Successful Treatment with Sertraline: A Clinical Trial Study

2020 ◽  
Vol 26 (4) ◽  
pp. 386-392
Author(s):  
Alireza Farnam ◽  
Arezoo Mehrara ◽  
Saeideh Aghayari Sheikh Neshin ◽  
Masumeh Zamanlu ◽  
Mohammad Ali Nazari ◽  
...  
Keyword(s):  
Anger Expression ◽  
Response To Treatment ◽  
Fourth Edition ◽  
Statistical Manual ◽  
Text Revision ◽  
Diagnostic And Statistical Manual ◽  
Violent Behaviors ◽  
Before And After ◽  
Dsm Iv ◽  
Standard Medication

Background: Depression associated with aggression can lead to violent behaviors. The present study was aimed to determine how sertraline, a standard medication for depression treatment, can efficiently decrease aggression and affect psychophysiological parameters in patients with depression. Methods: Patients with depression and aggression were included in a six-week trial with sertraline (50 100 mg/day). Depression diagnosis was confirmed by the Diagnostic and Statistical Manual of Mental Disorders, fourth edition, Text Revision (DSM-IV-TR). Depression severity before and after treatment was assessed using Beck Depression Inventory (BDI). Aggression was evaluated by Spielberger’s State-Trait Anger Expression Inventory-2 (STAXIII). The BDI and STAXI-II were finally applied to evaluate the effectiveness of treatment. For each patient, peripheral and central psychophysiological parameters were recorded using peripheral biofeedback apparatus and electroencephalogram in the initial and final stages of treatment. These recordings were attempted to assess variations of the autonomic nervous system and electrocortical activity in response to treatment. Results: Depressive and aggressive symptoms decreased significantly over the six-week treatment period, as measured by BDI and STAXI-II. Significant changes in some of the peripheral and central psychophysiological variables were observed. Sensorimotor rhythm (SMR)/theta ratio (p=0.01) have decreased during a task, delta (p=0.02) and theta (p=0.008) wave activity and theta/alpha ratio (p=0.01) have increased during task, and theta/beta ratio has increased during both rest and task (p=0.02 for both). Among peripheral psychophysiological variables, skin conductance during task decreased significantly (p=0.03). Conclusion: Several numbers of psychophysiological parameters were influenced significantly after successful pharmacotherapy of aggressiveness in patients with depression.

Introduction

CNS Spectrums ◽  
2007 ◽  
Vol 12 (S23) ◽  
pp. 4-5
Author(s):  
Lenard A. Adler ◽  
Jeffrey H. Newcorn
Keyword(s):  
Adult Adhd ◽  
The United States ◽  
Adhd Symptoms ◽  
Fourth Edition ◽  
Statistical Manual ◽  
Adhd Diagnosis ◽  
Text Revision ◽  
Hyperactivity Disorder ◽  
Diagnostic And Statistical Manual ◽  
Dsm Iv

Attention-deficit/hyperactivity disorder (ADHD) may be the most common chronic, undiagnosed psychiatric disorder in adults. ADHD is characterized by restlessness, overactivity, disorganization, impulsivity, and inattention; and as further characterized in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR). For most cases, an adult ADHD diagnosis is preceded by symptoms in childhood, which is a time when the disorder is rarely inquired about and usually overlooked.ADHD has been recognized in children for several decades, and the importance of detection and treatment is well established. Whereas it was initially believed that children outgrew the disease, researchers now know that approximately two thirds of children affected with ADHD symptoms carry the condition into adolescence and then into adulthood. Consequently, >4% of adults in the United States have ADHD. Nevertheless, the disorder is unrecognized and untreated in the vast majority of these people.

scholarly journals Clinical characterization of Italian suicide attempters with bipolar disorder

CNS Spectrums ◽  
2017 ◽  
Vol 23 (4) ◽  
pp. 271-277 ◽  
Author(s):  
Bernardo Dell’Osso ◽  
Matteo Vismara ◽  
Cristina Dobrea ◽  
Laura Cremaschi ◽  
Benedetta Grancini ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Fourth Edition ◽  
Statistical Manual ◽  
Clinical Variables ◽  
Text Revision ◽  
Diagnostic And Statistical Manual ◽  
Psychiatric Hospitalizations ◽  
Risk Patients ◽  
Dsm Iv

IntroductionBipolar disorder (BD) is a chronic, highly disabling condition associated with psychiatric/medical comorbidity and substantive morbidity, mortality, and suicide risks. In prior reports, varying parameters have been associated with suicide risk.ObjectivesTo evaluate sociodemographic and clinical variables characterizing Italian individuals with BD with versus without prior suicide attempt (PSA).MethodsA sample of 362 Italian patients categorized as BD according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM IV-TR) was assessed and divided in 2 subgroups: with and without PSA. Sociodemographic and clinical variables were compared between prior attempters and non-attempters using corrected multivariate analysis of variance (MANOVA).ResultsMore than one-fourth of BD patients (26.2%) had a PSA, with approximately one-third (31%) of these having>1 PSA. Depressive polarity at onset, higher number of psychiatric hospitalizations, comorbid alcohol abuse, comorbid eating disorders, and psychiatric poly-comorbidity were significantly more frequent (p<.05) in patients with versus without PSA. Additionally, treatment with lithium, polypharmacotherapy (≥4 current drugs) and previous psychosocial rehabilitation were significantly more often present in patients with versus without PSA.ConclusionsWe found several clinical variables associated with PSA in BD patients. Even though these retrospective findings did not address causality, they could be clinically relevant to better understanding suicidal behavior in BD and adopting proper strategies to prevent suicide in higher risk patients.

The Classification of Eating Disorders

2010 ◽  
pp. 7-24 ◽  
Author(s):  
Kathryn H. Gordon ◽  
Jill M. Holm-Denoma ◽  
Ross D. Crosby ◽  
Stephen A. Wonderlich
Keyword(s):  
Eating Disorders ◽  
Eating Disorder ◽  
Latent Class ◽  
Minority Groups ◽  
Statistical Manual ◽  
Text Revision ◽  
Diagnostic And Statistical Manual ◽  
Key Issues ◽  
Dsm Iv

The purpose of the chapter is to elucidate the key issues regarding the classification of eating disorders. To this end, a review of nosological research in the area of eating disorders is presented, with a particular focus on empirically based techniques such as taxometric and latent class analysis. This is followed by a section outlining areas of overlap between the current Diagnostic and Statistical Manual of Mental Disorders – Fourth Edition, Text Revision (DSM-IV-TR; American Psychiatric Association, 2000) eating disorder categories and their symptoms. Next, eating disorder classification models that are alternatives to the DSM-IV-TR are described and critically examined in light of available empirical data. Finally, areas of controversy and considerations for change in next version of the DSM (i.e., the applicability of DSM criteria to minority groups, children, males; the question of whether clinical categories should be differentiated from research categories) are discussed.

Sexual Disorders Not Otherwise Specified: Compulsive, Addictive, or Impulsive?

CNS Spectrums ◽  
2000 ◽  
Vol 5 (1) ◽  
pp. 60-66 ◽  
Author(s):  
Dan J. Stein ◽  
Donald W. Black ◽  
Willie Pienaar
Keyword(s):  
Sexual Disorders ◽  
Fourth Edition ◽  
Comprehensive Understanding ◽  
Hypersexual Disorder ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Not Otherwise Specified ◽  
Dsm Iv ◽  
Definition Of ◽  
High Comorbidity

AbstractParaphilias are recurrent and intense sexually arousing fantasies, sexual urges, or behaviors generally involving nonhuman objects. These paraphilias cause the suffering or humiliation of the patient or patient's partner, or children, or other nonconsenting persons. However, in many patients symptoms involve more culturally acceptable patterns (eg, repetitive masturbation, Internet pornography); such hypersexual symptoms have been labeled as compulsive, addictive, or impulsive. Growing evidence supports the existence of a discrete syndrome characterized by recurrent and intense sexually arousing fantasies, sexual urges, or behaviors involving patterns that fall outside the definition of paraphilia. There is, however, high comorbidity with paraphilia. While such symptoms have been labeled as sexual compulsion or addiction, these terms are problematic in this context. Modern nosology has neglected this entity, although the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), category of sexual disorders not otherwise specified includes hypersexual behaviors as an example. We suggest that the DSM-IV category of sexual disorders be modified to include explicitly diagnostic criteria for a disorder characterized by hypersexual symptoms involving patterns that fall outside of the current definition of paraphilia. The disorder might be classified as one of the paraphilias, or as paraphilia-related. In the absence of a comprehensive understanding of the pathogenesis of this disorder, we suggest that it simply be termed hypersexual disorder.

WHAT'S IN A LABEL? HELPING UNDERGRADUATE STUDENTS BECOME FAMILIAR WITH THE DSM IN PREPARATION FOR THEIR SENIOR YEAR FIELDWORK PRACTICA1

2003 ◽  
Vol 9 (1) ◽  
pp. 79-92 ◽  
Author(s):  
ROBERT H. KEEFE ◽  
CARRIE JEFFERSON SMITH ◽  
WILLIAM R. MCPEAK
Keyword(s):  
Undergraduate Students ◽  
Fourth Edition ◽  
Senior Year ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Dsm Iv

This paper explores the development of an undergraduate course module devoted to the American Psychiatric Association's Diagnostic and Statistical Manual: Fourth Edition (DSM-IV). The skills-based course in which this module is presented is focused on helping junior year BSW students to prepare for their senior year fieldwork practica. Students enrolled in this course between 1998 and 2000 were surveyed. The results indicate that the respondents found the course module to be helpful not only in preparing them for their senior year fieldwork practica but also in their post-BSW employment and MSW programs as well. An excerpt from the module is included as an appendix.

Bereavement and Depression: Possible Changes to the Diagnostic and Statistical Manual of Mental Disorders: A Report from the Scientific Advisory Committee of the Association for Death Education and Counseling

2011 ◽  
Vol 63 (3) ◽  
pp. 199-220 ◽  
Author(s):  
David E. Balk ◽  
Illene Noppe Cupit ◽  
Irwin Sandler ◽  
James Werth
Keyword(s):  
Mental Disorders ◽  
Advisory Committee ◽  
Fourth Edition ◽  
Death Education ◽  
Major Depressive ◽  
Scientific Advisory Committee ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Scientific Advisory ◽  
Dsm Iv

The fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) is being revised. A proposed revision hotly debated is to remove what is known as the exclusionary criterion and allow clinicians to diagnose a person with a major depressive episode within the early days and weeks following a death. The Executive Committee of the Association for Death Education and Counseling (ADEC) commissioned its Scientific Advisory Committee (SAC) to examine the debate over removing the exclusionary criterion and provide a written report. The DSM-IV-TR classifies bereavement as a clinical condition that is not a mental disorder. The exclusionary criterion states that within the first 2 months of the onset of bereavement a person should not be diagnosed as having major depression unless certain symptoms not characteristic of a normal grief reaction are present. We note these symptoms when discussing the exclusionary criterion, examine reasons (including research conclusions and clinical concerns) given for retaining and for eliminating the exclusionary criterion, offer extensive comments from experienced licensed clinicians about the issues involved, discuss diagnostic and treatment implications, and offer specific recommendations for ADEC to implement.

Prevalence of Psychotic Disorders in Patients with Obsessive-Compulsive Disorder

CNS Spectrums ◽  
2009 ◽  
Vol 14 (8) ◽  
pp. 415-418 ◽  
Author(s):  
Lieuwe de Haan ◽  
Christine Dudek-Hodge ◽  
Yolanda Verhoeven ◽  
Damiaan Denys
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Psychotic Disorder ◽  
Psychotic Disorders ◽  
Fourth Edition ◽  
Obsessive Compulsive ◽  
Statistical Manual ◽  
Compulsive Disorder ◽  
Diagnostic And Statistical Manual ◽  
Dsm Iv ◽  
Clinical Characteristic

ABSTRACTIntroduction: The co-occurrence of obsessive-compulsive disorder (OCD) in patients with schizophrenia and related disorders has been increasingly recognized. However, the rate of psychosis comorbidity in OCD patients has yet to be systematically evaluated.Methods: The prevalence of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition psychotic disorders was evaluated in 757 subjects consecutively referred to a specialised diagnostic and treatment facility for OCD. Demographic and clinical characteristics were assessed.Results: Thirteen OCD patients (1.7%) also met the DSM-IV criteria for a psychotic disorder. We found no significant differences in clinical characteristic between OCD patients with and without a psychotic disorder, although patients with OCD and a psychotic disorder more likely used illicit substances and more likely were male.Conclusion: Relatively few patients referred to a specialized treatment OCD center suffer from a psychotic disorder.

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