scholarly journals The Risk Factors for Development of Emergency Conditions in Tender-Age Infants in Acute Intestinal Infections of Different Etiologies

Author(s):  
Z.M. Kuliyeva ◽  
L.I. Rustamova ◽  
M.N. Mammadova ◽  
I.B. Israfilbekova ◽  
T.I. Ibadova

Among the leading risk factors for the development of emergency conditions in acute intestinal infections, especially in infants, some authors point to rickets, anemia, and abnormal antenatal pathology. The aim is to determine the frequency of occurrence of various risk factors for the development of emergency situations in tender-age infants. Materials and methods: 338 tender-age infants with urgent conditions were under observation. The study involved clinical-anamnestic, bacteriological, and serological methods. The aggravating factors were as follows: diseases of parents in 16 (6.2%), related marriages - 20 (7.7%) pregnancy pathology-137 (52.9%), prematurity-16 (6.2%), artificial feeding - 127 (49.0%), early diseases (acute respiratory viral infections, pneumonia, encephalopathy, intestinal infections). Results: According to the results of the study, the central nervous system damage was most often observed in children from 1 month to 6 months (80.2%), anemia was more detected in children of 1-3 years - 56.4%, rickets was more diagnosed in children aged 6-12 months -38.2%.

1981 ◽  
Vol 62 (5) ◽  
pp. 24-26
Author(s):  
O. I. Pikuza ◽  
L. A. Kuznetsova ◽  
L. Y. Aleksandrova

The study of the clinical features of acute respiratory viral infections and pneumonia in 320 newborns made it possible to identify a group of children with an increased risk of an unfavorable course of the disease. A negative effect on the prognosis of acute respiratory diseases in newborns is exerted by toxicosis, acute diseases of women during pregnancy, the impact on the expectant mother of occupational health problems, a burdened obstetric history, prematurity of the newborn, natal trauma of the central nervous system. Specific regimens have been developed to complement the conventional medical history that can facilitate the management of risk conditions and a differentiated approach to the newborn.


2000 ◽  
Vol 6 (1) ◽  
pp. 66-75
Author(s):  
R. Singh ◽  
O. Al Sudani

A study was conducted to investigate the magnitude, nature and associated risk factors of major congenital anomalies [MCAs]at birth in Benghazi, Libyan Arab Jamahiriya in 1995. The incidence of MCAs was 7.4 per 1000 live births and 9.3 per 1000 total births. The rate was higher in summer, in babies born to mothers over 40 years and low-birth-weight babies or those born preterm or post-term. In 56.1% of cases there were multiple congenital anomalies and > two-thirds of the major congenital anomalies were chromosomal, musculoskeletal or of the central nervous system. The incidence of perinatal death in births with MCAs was 49.1% compared with 2.7% for all births


Blood ◽  
2013 ◽  
Vol 121 (10) ◽  
pp. 1906-1910 ◽  
Author(s):  
Steffen Hartrampf ◽  
Jarrod A. Dudakov ◽  
Linda K. Johnson ◽  
Odette M. Smith ◽  
Jennifer Tsai ◽  
...  

Key Points The central nervous system can be a direct target of alloreactive T cells during GVHD. Central nervous system damage in mouse models of GVHD lead to deficits in learning and increased anxiety behavior.


2016 ◽  
Author(s):  
◽  
Christopher M. Owens

Injuries to nerves vary in their consequences, from weakened sensation and motor function to partial or complete paralysis. In the latter case, affecting about twenty thousand Americans yearly, the injury is debilitating and results in a significant decrease in quality of life. Currently there is no effective treatment for damage to the central nervous system, in particular the spinal cord. Compared to the injuries to the central nervous system, damage in the peripheral nerves, is more common, with about sixty thousand occurrences annually. The cost of associated surgical procedures and due to loss of function is in the billions. In this thesis we present work towards the construction and testing of a fully cellular, patented nerve graft, one amongst the first of its kind. For the fabrication of the graft we are the first to employ bioprinting (either implemented through a special purpose 3D bioprinter or manually), a novel tissue engineering method rapidly gaining acceptance and utility. We first review the status of bioprinting. We then detail the fabrication process. Next we report on the testing of the graft in an in vivo animal model through electrophysiology and histology. This is followed by the introduction of a novel in vitro model, aimed at providing a fast, inexpensive and reliable method to test engineered nerve grafts. We describe our work on the optimization of the in vitro assay and then the testing of the graft using the optimized assay. We conclude with a summary of our accomplishments and make suggestions for some exciting future applications of our approach.


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