scholarly journals Risk factors for respiratory viral infections in newborns

1981 ◽  
Vol 62 (5) ◽  
pp. 24-26
Author(s):  
O. I. Pikuza ◽  
L. A. Kuznetsova ◽  
L. Y. Aleksandrova
Keyword(s):  
Risk Factors ◽  
Respiratory Diseases ◽  
Viral Infections ◽  
Expectant Mother ◽  
Increased Risk ◽  
Negative Effect ◽  
Acute Respiratory Diseases ◽  
The Central Nervous System ◽  
Respiratory Viral Infections ◽  
The Impact

The study of the clinical features of acute respiratory viral infections and pneumonia in 320 newborns made it possible to identify a group of children with an increased risk of an unfavorable course of the disease. A negative effect on the prognosis of acute respiratory diseases in newborns is exerted by toxicosis, acute diseases of women during pregnancy, the impact on the expectant mother of occupational health problems, a burdened obstetric history, prematurity of the newborn, natal trauma of the central nervous system. Specific regimens have been developed to complement the conventional medical history that can facilitate the management of risk conditions and a differentiated approach to the newborn.

scholarly journals The Risk Factors for Development of Emergency Conditions in Tender-Age Infants in Acute Intestinal Infections of Different Etiologies

2021 ◽  
pp. 23-28
Author(s):  
Z.M. Kuliyeva ◽  
L.I. Rustamova ◽  
M.N. Mammadova ◽  
I.B. Israfilbekova ◽  
T.I. Ibadova
Keyword(s):  
Risk Factors ◽  
Central Nervous System ◽  
Viral Infections ◽  
Artificial Feeding ◽  
Frequency Of Occurrence ◽  
Central Nervous System Damage ◽  
Emergency Situations ◽  
Intestinal Infections ◽  
The Central Nervous System ◽  
Respiratory Viral Infections

Among the leading risk factors for the development of emergency conditions in acute intestinal infections, especially in infants, some authors point to rickets, anemia, and abnormal antenatal pathology. The aim is to determine the frequency of occurrence of various risk factors for the development of emergency situations in tender-age infants. Materials and methods: 338 tender-age infants with urgent conditions were under observation. The study involved clinical-anamnestic, bacteriological, and serological methods. The aggravating factors were as follows: diseases of parents in 16 (6.2%), related marriages - 20 (7.7%) pregnancy pathology-137 (52.9%), prematurity-16 (6.2%), artificial feeding - 127 (49.0%), early diseases (acute respiratory viral infections, pneumonia, encephalopathy, intestinal infections). Results: According to the results of the study, the central nervous system damage was most often observed in children from 1 month to 6 months (80.2%), anemia was more detected in children of 1-3 years - 56.4%, rickets was more diagnosed in children aged 6-12 months -38.2%.

scholarly journals Significance of complex laboratory diagnostics of ARVI for veterinary practice

2020 ◽  
Vol 196 (5) ◽  
pp. 59-67
Author(s):  
A. PORYVAEVA ◽  
O Petrova ◽  
Elena Pechura ◽  
Natalia Bezborodova ◽  
Ya. LYSOVA
Keyword(s):  
Respiratory Diseases ◽  
Viral Infections ◽  
Respiratory Infections ◽  
Federal District ◽  
Laboratory Diagnostics ◽  
Agricultural Enterprises ◽  
Udmurt Republic ◽  
Acute Respiratory Diseases ◽  
Respiratory Viral Infections ◽  
Diagnostic Technologies

Abstract. This article summarizes the results of laboratory studies of acute respiratory viral infections of cattle in agricultural enterprises of the Ural Federal district and the Udmurt Republic. The purpose of the research was to show the spread of respiratory viral infections in cattle in various regions and the significance of laboratory diagnostics in this pathology. According to research data 815 samples for the period 2018–2020 a variety of combinations of mixed respiratory viruses in animals was detected using biomaterials from different age patients and patients with respiratory diseases of cattle from agricultural enterprises of the Ural Federal district, the Volga Federal District and the Udmurt Republic using polymerase chain reaction, indirect hemagglutination reaction, hemagglutination inhibition reaction, Elisa , and enzyme immunoassay. Scientific novelty. The etiological structure of mixed acute respiratory viral infections in cattle in agricultural enterprises in four regions of the Ural Federal District, the Volga Federal District and the Udmurt Republic in 2018–2020 was studied using modern diagnostic technologies. Results. In the Ural Federal District, the Volga Federal district and the Udmurt Republic, 80 % of cases of acute respiratory diseases were caused by bovine viral infections, mainly representatives of 2 families of viruses whose genome is represented by an RNA molecule (paramixoviruses, togaviruses) and a family of viruses whose genome is represented by a DNA molecule (herpesviruses,). The leading place among acute respiratory infections was occupied by infectious rhinotracheitis of cattle.

ARVI and pregnancy: prevention options

2020 ◽  
Vol 19 (6) ◽  
pp. 145-152
Author(s):  
L.V. Posiseeva ◽  
◽  
D.S. Kuksa ◽  
◽  
Keyword(s):  
Risk Factors ◽  
Viral Infections ◽  
Newborn Health ◽  
Pregnancy Risk ◽  
Recombinant Interferon ◽  
Her Family ◽  
Perinatal Pathology ◽  
Interferon Alpha 2B ◽  
Respiratory Viral Infections ◽  
The Impact

This paper addresses the main issues related to the incidence of Acute Respiratory Viral Infections (ARVI), including influenza and COVID-19, in pregnant women, the impact of these infections on the pregnancy course, fetal and newborn health. Risk factors for ARVI complications have been determined, taking into account the pregnancy term, the woman’s age and concomitant somatic diseases. A special attention was given to the specific (vaccination) and nonspecific ARVI prevention (the use of recombinant interferon alpha-2b, the medicine Grippferon) during the pregnancy preparation stage not only for the expectant mother, but also for all her family members. The results of the effective use of the interferon-based medicine Grippferon for the prevention and treatment of ARVI during pregnancy are provided. This medicine helps to reduce the frequency of ARVI-related pregnancy complications and perinatal pathology. Keywords: acute respiratory viral infections, pathogens, pregnancy, risk factors, prevention, interferon-based medicines, Grippferon

Psychological aspects of history e-learning

2021 ◽  
Vol 2021 (03) ◽  
pp. 158-172
Author(s):  
Mikhail Matveev
Keyword(s):  
Chronic Infection ◽  
Respiratory Diseases ◽  
Viral Infections ◽  
Rna Viruses ◽  
Psychological Aspects ◽  
Viral Pathogens ◽  
E Learning ◽  
Acute Respiratory Diseases ◽  
Respiratory Viral Infections

Acute respiratory viral infections (ARVI) cause more than 80% of all acute respiratory diseases. Like most viral pathogens of SARS, coronaviruses are RNA viruses, but they have the largest genome in terms of size - about 29 thousand nucleotides. Live anti-coronavirus vaccines have been developed for dogs and domestic chickens, because their respective varieties cause severe chronic infection and high viral mortality.

Evaluation of clinical efficacy of Derinat® in form of spray in practice of district therapist

2019 ◽  
Vol 1 (9) ◽  
pp. 38-46
Author(s):  
A. P. Babkin ◽  
A. A. Zuikova ◽  
O. N. Krasnorutskaya ◽  
Yu. A. Kotova ◽  
D. Yu. Bugrimov ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Respiratory Diseases ◽  
Viral Infections ◽  
Pharmacological Action ◽  
The Body ◽  
Natural Resistance ◽  
Acute Respiratory Diseases ◽  
T Helpers ◽  
T Killers ◽  
Stimulation Of

The widespread worldwide spread of acute respiratory diseases is an urgent problem in health care. Expressed polyetiology of respiratory diseases does not allow to limit the use of specific vaccine preparations and dictates the need to use to combat them a variety of non-specific means that stimulate the natural resistance of the human body. The main pharmacological action of sodium deoxyribonucleate is the stimulation of phagocytic activity of T-helpers and T-killers, increasing the functional activity of neutrophils and monocytes/ macrophages, providing regeneration and repair processes in the epithelial component of antiviral protection of the body. Based on the above, the study of the clinical efficacy of Derinat® in the form of spray in the treatment of acute respiratory viral infections is relevant.

Abstract T P136: Potential Contributors to the Declining Impact of Stroke Risk Factors with Age: Implications for Stroke Epidemiology in the Elderly

Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
George Howard ◽  
Mary Cushman ◽  
Maciej Banach ◽  
Brett M Kissela ◽  
David C Goff ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Stroke Risk ◽  
Multivariable Analysis ◽  
The Elderly ◽  
Stroke Risk Factors ◽  
Age Related ◽  
Increased Risk ◽  
The Impact ◽  
Age Related Changes

Purpose: The importance of stroke research in the elderly is increasing as America is “graying.” For most risk factors for most diseases (including stroke), the magnitude of association with incident events decreases at older ages. Potential changes in the impact of risk factors could be a “true” effect, or could be due to methodological issues such as age-related changes in residual confounding. Methods: REGARDS followed 27,748 stroke-free participants age 45 and over for an average of 5.3 years, during which 715 incident strokes occurred. The association of the “Framingham” risk factors (hypertension [HTN], diabetes, smoking, AFib, LVH and heart disease) with incident stroke risk was assessed in age strata of 45-64 (Young), 65-74 (Middle), and 75+ (Old). For those with and without an “index” risk factor (e.g., HTN), the average number of “other” risk factors was calculated. Results: With the exception of AFib, there was a monotonic decrease in the magnitude of the impact across the age strata, with HTN, diabetes, smoking and LVH even becoming non-significant in the elderly (Figure 1). However, for most factors, the increasing prevalence of other risk factors with age impacts primarily those with the index risk factor absent (Figure 2, example HTN as the “index” risk factor). Discussion: The impact of stroke risk factors substantially declined at older ages. However, this decrease is partially attributable to increases in the prevalence of other risk factors among those without the index risk factor, as there was little change in the prevalence of other risk factors in those with the index risk factor. Hence, the impact of the index risk factor is attenuated by increased risk in the comparison group. If this phenomenon is active with latent risk factors, estimates from multivariable analysis will also decrease with age. A deeper understanding of age-related changes in the impact of risk factors is needed.

scholarly journals Acute respiratory viral infections: possibilities of symptomatic therapy of patients

2021 ◽  
pp. 103-111
Author(s):  
G. N. Nikiforova ◽  
V. M. Svistushkin ◽  
A. V. Zolotova ◽  
M. A. Morozova
Keyword(s):  
Viral Infections ◽  
Symptomatic Therapy ◽  
Nasal Breathing ◽  
General Weakness ◽  
Rapid Changes ◽  
Acute Respiratory Diseases ◽  
Respiratory Viral Infections ◽  
Instructions For Use ◽  
Combined Drugs

Acute respiratory viral infections are widespread in the human population. High contagiosity, a wide variety of pathogens, the possibility of rapid changes in the genotype of the virus and, accordingly,cause the development of drug resistance, make it possible to develop epidemics, and sometimes pandemics of SARS.The clinical picture of all acute respiratory diseases consists of local and general manifestations. Local symptoms include difficulty in nasal breathing, rhinorrhea, pain and discomfort in the throat, cough, hoarseness, stuffy ears, and lacrimation. General manifestations of SARS indicate the onset of viremia, and include an increase in body temperature, general weakness, fatigue, malaise, and headache. The mechanism of SARS development determines the  treatment tactics, including etiotropic, pathogenetic and symptomatic therapy.Domestic and international clinical recommendations indicate the  possible use of  symptomatic agents for  SARS and influenza.Symptomatic treatment is one of the areas of therapy for patients with influenza and other acute respiratory viral infections and allows you to alleviate the general condition, accelerate recovery and improve the quality of life of patients. The use of combined drugs is safer for patients thenthanmonocomponent drugs, and is safe for patients, in case the instructions for use are strictly observed. Such complex medicines, which provides control of the symptoms of colds and flu within 24 hours, as domestic drug are used for patients with SARS. Due to its components, drughas antipyretic, anti-inflammatory, analgesic, anti-allergic, angioprotective and vasoconstrictive effects. The synergism of the components of the combined drug allows to increase the effectiveness of therapy of patients with acute respiratory viral infections.

scholarly journals USED OF BREATHING EXERCISES FOR PRIMARY SCHOOL CHILDREN AS NON-SPECIFIC MEANS OF PREVENTION OF ACUTE RESPIRATORY VIRAL DISEASES (REVIEW)

2018 ◽  
Vol 64 ◽  
Author(s):  
A.S. Kalabukhova ◽  
M.P. Radziejowska
Keyword(s):  
Respiratory Diseases ◽  
Viral Infections ◽  
Primary School Children ◽  
Viral Diseases ◽  
Physical Culture ◽  
Breathing Exercises ◽  
System Disease ◽  
Respiratory System Disease ◽  
Training Courses ◽  
Respiratory Viral Infections

In the article was reviewed and analyzed scientific and methodological literature on the spread of respiratory diseases in children. The existing methods of nonspecific prevention of respiratory diseases are considered by means of various modifications of breathing exercises. The influence of therapeutic physical culture as a means to stimulate the immune response in case of respiratory system disease was substantiated. Also, was analyzed organization of conducting physical education lessons for children who had respiratory diseases. The emphasis is on the need for changes in the content of physical training courses to increase the effectiveness of the fight against acute respiratory viral infections.

scholarly journals COVID-19 Mortality is Associated with Impaired Innate Immunity in Pre-existing Health Conditions

2021 ◽  
Author(s):  
Matthew E Lee ◽  
Yung Chang ◽  
Navid Ahmadinejad ◽  
Crista E Johnson-Agbakwu ◽  
Celeste Bailey ◽  
...  
Keyword(s):  
Risk Factors ◽  
Innate Immunity ◽  
Viral Infections ◽  
Enrichment Analysis ◽  
Gene Set Enrichment Analysis ◽  
Therapeutic Interventions ◽  
Health Conditions ◽  
Molecular Abnormalities ◽  
Hazard Ratios ◽  
Increased Risk

Background: COVID-19 poses a life-threatening endangerment to individuals with chronic diseases. However, not all comorbidities affect COVID-19 prognosis equally. Some increase the risk of COVID-19 related death by more than six folds while others show little to no impact. To prevent severe outcomes, it is critical that we comprehend pre-existing molecular abnormalities in common health conditions that predispose patients to poor prognoses. In this study, we aim to discover some of these molecular risk factors by associating gene expression dysregulations in common health conditions with COVID-19 mortality rates in different cohorts. Methods: We focused on fourteen pre-existing health conditions, for which age-and-sex-adjusted hazard ratios of COVID-19 mortality have been documented. For each health condition, we analyzed existing transcriptomics data to identify differentially expressed genes (DEGs) between affected individuals and unaffected individuals. We then tested if fold changes of any DEG in these pre-existing conditions were correlated with hazard ratios of COVID-19 mortality to discover molecular risk factors. We performed gene set enrichment analysis to identify functional groups overrepresented in these risk factor genes and examined their relationships with the COVID-19 disease pathway. Results: We found that upregulated expression of 70 genes and downregulated expression of 181 genes in pre-existing health conditions were correlated with increased risk of COVID-19 related death. These genes were significantly enriched with endoplasmic reticulum (ER) function, proinflammatory reaction, and interferon production that participate in viral transcription and immune responses to viral infections. Conclusions: Impaired innate immunity in pre-existing health conditions are associated with increased hazard of COVID-19 mortality. The discovered molecular risk factors are potential prognostic biomarkers and targets for therapeutic interventions.

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