scholarly journals Perbandingan Ketebalan Retina Sentral Pasien Hipertensi Esensial tanpa Penurunan Visus Dibanding Orang Normal

e-CliniC ◽  
2019 ◽  
Vol 7 (2) ◽  
Author(s):  
Ade J. Nursalim ◽  
Vera Sumual ◽  
Eugeni Sumanti
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Thickness ◽  
Normal Group ◽  
Hypertensive Retinopathy ◽  
Optical Coherence ◽  
Hypertensive Patients ◽  
Normal People ◽  
Central Retina ◽  
Significant Difference ◽  
Prospective Comparative Study

Abstract: One of the complications of hypertension is hypertensive retinopathy with a prevalence of 2-17% in patients with hypertension without diabetes. Application of optical coherence tomography (OCT) tool enables the clinician to simplify the pathophysiological process of hypertensive retinopathy. This study was aimed to compare the central retina thickness of essential hypertensive patients without decreased vision to of normal people. This was a prospective comparative study using a quantitative method. There were 56 eyes in the hypertension group and 71 eyes in the normal group. The t test showed that central retina thickness in hypertension group was 201.66 μm (SD ±38,870) meanwhile in the normal group was 249.59 μm (SD±19,245) (p=0.004). In conclusion, there was a significant difference in central retinal thickness between essential hypertensive patients and normal people. It is suggested that ophthalmologic examination should be performed on patients with essential hypertension even without decreased vision.Keywords: hypertension, decrease of vision, retinal thickness Abstrak: Salah satu komplikasi hipertensi yaitu retinopati hipertensi dengan prevalensi 2-17% pada penyandang hipertensi tanpa diabetes. Aplikasi alat optical coherence tomography (OCT) memungkinkan klinisi untuk meneliti lebih lanjut mengenai proses patofisiologi retinopati hipertensi. Penelitian ini bertujuan untuk membandingkan ketebalan retina sentral pasien hipertensi esensial tanpa penurunan visus dibanding orang normal. Jenis penelitian ialah prospektif komparatif menggunakan metode kuantitatif. Hasil penelitian mendapatkan 56 mata untuk kelompok hipertensi dan 71 mata untuk kelompok normal yang memenuhi kriteria penelitian. Uji t menunjukkan terdapat perbedaan ketebalan retina sentral pada kelompok hipertensi dibanding kelompok normal. Rerata ketebalan retina pada kelompok hipertensi ialah 201,66 μm (SD±38,870) dibanding pada kelompok normal ialah 249,59 μm (SD±19,245) (p=0,004). Simpulan penelitian ini ialah terdapat perbedaan bermakna antara ketebalan retina sentral pasien hipertensi esensial tanpa penurunan visus dibanding orang normal. Disarankan untuk melakukan pemeriksaan mata pada penyandang hipertensi esensial meskipun belum disertai keluhan penurunan tajam penglihatan.Kata kunci: hipertensi, penurunan visus, ketebalan retina

scholarly journals Perbandingan Ketebalan Retina Sentral Pasien Hipertensi Esensial tanpa Penurunan Visus Dibanding Orang Normal

e-CliniC ◽  
2019 ◽  
Vol 7 (2) ◽  
Author(s):  
Ade J. Nursalim ◽  
Vera Sumual ◽  
Eugeni Sumanti
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Thickness ◽  
Normal Group ◽  
Hypertensive Retinopathy ◽  
Optical Coherence ◽  
Hypertensive Patients ◽  
Normal People ◽  
Central Retina ◽  
Significant Difference ◽  
Prospective Comparative Study

Abstract: One of the complications of hypertension is hypertensive retinopathy with a prevalence of 2-17% in patients with hypertension without diabetes. Application of optical coherence tomography (OCT) tool enables the clinician to simplify the pathophysiological process of hypertensive retinopathy. This study was aimed to compare the central retina thickness of essential hypertensive patients without decreased vision to of normal people. This was a prospective comparative study using a quantitative method. There were 56 eyes in the hypertension group and 71 eyes in the normal group. The t test showed that central retina thickness in hypertension group was 201.66 μm (SD ±38,870) meanwhile in the normal group was 249.59 μm (SD±19,245) (p=0.004). In conclusion, there was a significant difference in central retinal thickness between essential hypertensive patients and normal people. It is suggested that ophthalmologic examination should be performed on patients with essential hypertension even without decreased vision.Keywords: hypertension, decrease of vision, retinal thickness Abstrak: Salah satu komplikasi hipertensi yaitu retinopati hipertensi dengan prevalensi 2-17% pada penyandang hipertensi tanpa diabetes. Aplikasi alat optical coherence tomography (OCT) memungkinkan klinisi untuk meneliti lebih lanjut mengenai proses patofisiologi retinopati hipertensi. Penelitian ini bertujuan untuk membandingkan ketebalan retina sentral pasien hipertensi esensial tanpa penurunan visus dibanding orang normal. Jenis penelitian ialah prospektif komparatif menggunakan metode kuantitatif. Hasil penelitian mendapatkan 56 mata untuk kelompok hipertensi dan 71 mata untuk kelompok normal yang memenuhi kriteria penelitian. Uji t menunjukkan terdapat perbedaan ketebalan retina sentral pada kelompok hipertensi dibanding kelompok normal. Rerata ketebalan retina pada kelompok hipertensi ialah 201,66 μm (SD±38,870) dibanding pada kelompok normal ialah 249,59 μm (SD±19,245) (p=0,004). Simpulan penelitian ini ialah terdapat perbedaan bermakna antara ketebalan retina sentral pasien hipertensi esensial tanpa penurunan visus dibanding orang normal. Disarankan untuk melakukan pemeriksaan mata pada penyandang hipertensi esensial meskipun belum disertai keluhan penurunan tajam penglihatan.Kata kunci: hipertensi, penurunan visus, ketebalan retina

Effects of Retinal Angiography on Optical Coherence Tomography Measurements

2015 ◽  
Vol 234 (3) ◽  
pp. 160-166 ◽  
Author(s):  
Young-Joon Jo ◽  
Hyung-Bin Lim ◽  
Soo-Hyun Lee ◽  
Jung-Yeul Kim
Keyword(s):  
Optical Coherence Tomography ◽  
Indocyanine Green ◽  
Retinal Thickness ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Nerve Fiber Layer Thickness ◽  
Interclass Correlation ◽  
Significant Difference ◽  
Before And After ◽  
Sd Oct

Purpose: To evaluate the effects of retinal angiography, using fluorescein and indocyanine green dyes, on optical coherence tomography (OCT) measurements. Methods: In total, 76 eyes from 76 consecutive patients were included. Macular cube 512 × 128 combination scanning and optic disc 200 × 200 scanning using spectral-domain (SD)-OCT were performed twice, before and after retinal angiography, with fluorescein or indocyanine green. Signal strength, regional retinal thickness of the 9 Early Treatment Diabetic Retinopathy Study subfields, total macular volume, and retinal nerve fiber layer thickness obtained before and after angiography were compared. Repeatability was also investigated. Results: Comparing the results of OCT measured before and after retinal angiography, there was no statistically significant difference in any parameter assessed. The interclass correlation values for each measurement were all >0.808 (range 0.808-0.999). Conclusion: Retinal angiography using fluorescein and indocyanine green dyes has no significant effect on OCT measurements.

scholarly journals Macular Thickness and Volume Assessed by Spectral-Domain Optical Coherence Tomography in Patients With Coronavirus Disease 2019: A Case-Control Study

2020 ◽  
Author(s):  
Mojtaba Abrishami ◽  
Fariba Tohidinezhad ◽  
Zahra Emamverdian ◽  
Ramin Daneshvar ◽  
Neda Saeedian ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Thickness ◽  
Spectral Domain ◽  
Case Group ◽  
Special Focus ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Significant Difference ◽  
Normal Controls ◽  
Sd Oct

Abstract Purpose: To quantify the retinal thickness and volume using spectral-domain optical coherence tomography (SD-OCT) analysis in the macular region of patients with Coronavirus Disease 2019 (COVID-19).Methods: In a comparative cross-sectional, observational study, patients recovered from COVID-19 were included. All included subjects had a reverse transcription-polymerase chain reaction (RT-PCR) - confirmed diagnosis of COVID-19. Macular SD-OCT was performed at least two weeks after recovery from systemic COVID-19. Inner, outer and full retinal thicknesses and volumes were measured in COVID-19 recovered patients versus age-matched normal controls.Results: Twenty-five patients (11 male) with a mean age of 36.4 ± 11 years and 60 healthy controls (31 males) with a mean age of 39.3 ± 7.7 years were enrolled in the study. There was no statistically significant difference in the retinal thickness or volume measures between the two groups. However, the thickness in the case group was minimally more than the controls. Conclusion: Retinal thickness in COVID-19 patients may be higher than healthy subjects. Comprehensive ocular examination with special focus on posterior segment manifestations should be considered in these patients.

scholarly journals Assessment of the Effectiveness of Obstructive Sleep Apnea Treatment Using Optical Coherence Tomography to Evaluate Retinal Findings

2021 ◽  
Author(s):  
Gloria Tejero-Garcés ◽  
Francisco J Ascaso ◽  
Paula Casas ◽  
Maria I Adiego ◽  
Peter Baptista ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Optical Coherence Tomography ◽  
Sleep Apnea ◽  
Retinal Thickness ◽  
Sleep Apnea Syndrome ◽  
University Hospital ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Obstructive Sleep ◽  
Prospective Comparative Study

Retinal findings may change in patients with obstructive sleep apnea syndrome (OSAS). The present study aims to evaluate several retinal findings such as macula layer thickness, peripapillary retinal nerve fiber layer, and the optic nerve head in patients with OSAS using optical coherence tomography (OCT) and monitor the result of several types of treatment of OSAS with OCT. A prospective comparative study was designed. Patients were recruited at a Sleep Unit of a University Hospital and underwent comprehensive ophthalmological examinations. Following exclusion criteria, fifty-two patients with OSAS were finally included. Patients were examined by OCT twice: first, before treatment; secondly, after six months of treatment. In mild-moderate patients, where retinal swelling has been demonstrated, retinal thicknesses decreased [fovea (p=0.026), as well as inner ring macula (p=0.007), outer ring macula (p=0.015), and macular volume (p=0.015)]. In severe patients, where retinal atrophy had been observed, retinal thickness increased [fovea (p<0.001)]. No statistically significant differences in efficacy between treatments were demonstrated. In conclusion, OCT can evaluate the retina in patients with OSAS and help monitor results after treatment. In severe OSAS, retinal thickness increased six months after treatment.

Repeatability of Retinal Macular Thickness Measurements in Patients with Clinically Significant Macular Edema Using Two Different Scanning Protocols of Spectralis Optical Coherence Tomography

2015 ◽  
Vol 234 (3) ◽  
pp. 167-171 ◽  
Author(s):  
Tito Fiore ◽  
Marco Lupidi ◽  
Sofia Androudi ◽  
Fabrizio Giansanti ◽  
Daniela Fruttini ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Retinal Thickness ◽  
Diabetic Patients ◽  
Optical Coherence ◽  
Significant Difference ◽  
Clinically Significant Macular Edema ◽  
Clinically Significant ◽  
Thickness Measurements

Objective: To determine the repeatability of Spectralis optical coherence tomography (OCT) retinal thickness measurements in diabetic patients with clinically significant macular edema (CSME) using two different scanning protocols. Methods: Seventy-one eyes of 71 diabetic patients with CSME were included in the study. Coefficients of repeatability and intrasession variation coefficients were tested with 20 × 15 degree raster scans consisting of 19 or 37 high-resolution line scans (15 or 8 frames per scan, respectively) that were repeated 2 times by 1 experienced examiner. The first scan was set as the reference scan; the second scan was the follow-up scan and was performed with the use of the follow-up mode. Results: The mean and standard deviation for the central foveal subfield (CSF) using the first scanning method was 404 ± 88 μm, while it was 399 ± 86 μm using the second protocol, which was not statistically significantly different (p = 0.35, paired test). Particularly examining the CSF, the coefficient of repeatability was 1.48 (6.00 µm) and 1.49 (5.95 µm) for the 19- and the 37-B-scan acquisition, respectively, showing a nonstatistically significant difference (p < 0.001). Conclusions: Retinal thickness measurements in diabetic patients with CSME are repeatable using both scanning protocols (19 or 37 B-scans) with Spectralis OCT. The repeatability of the retinal thickness measurement does not improve by increasing the number of B-scans from 19 to 37.

scholarly journals Optical Coherence Tomography with Angiography in the Analysis of Vitrectomy Effectiveness in Patients with Vitreomacular Traction Syndrome

2020 ◽  
Vol 17 (1) ◽  
pp. 70-75
Author(s):  
T. G. Kamenskikh ◽  
I. O. Kolbenev ◽  
Y. A. Melnikova ◽  
O. A. Andreychenko
Keyword(s):  
Optical Coherence Tomography ◽  
Surgical Treatment ◽  
Postoperative Period ◽  
Retinal Thickness ◽  
Vitreomacular Traction ◽  
Control Group ◽  
Optical Coherence ◽  
Vitreomacular Traction Syndrome ◽  
Significant Difference ◽  
Retinal Microcirculation

Micro incision vitrectomy surgery with removal of epiretinal and internal limiting membranes is used for treating various forms of vitreomacular traction syndrome.Objective: to study the condition of retinal microcirculation using the OCTA method in the patients with traction maculopathy and macular ruptures before and after vitrectomy.Patients and Methods. The study included 160 patients, of which 55 had epiretinal fibrosis (Treatment 1), 60 had macular ruptures (Treatment 2), and 45 with no ophthalmic pathology (Control). Treatment 2 group included two subgroups: 2a — patients with large-diameter ruptures (over 800 μm) subject to inverted internal limiting membrane flap technique (n = 12), and 2b — patients with 430–800 μm ruptures subject to rapprochement of the rupture edges with a platelet mass technique. All patients underwent conventional ophthalmology examinations and optical coherence tomography angiography (OCTA) using Sirrus HD-OCT 5000, Carl Zeiss, Germany.Results. In the postoperative period, there was an improvement in retinal microcirculation in the Treatment 1 patients, and the values of both perfusion and vascular densities increased. A month later, an additional improvement of these indicators was recorded against the background of a decrease in retinal thickness and restoration of the vitreoretinal interface configuration. In the early postoperative period, Treatment 2 patients showed significant difference in the capillary density of the superficial vascular complex from the control group. A month later, the density of blood vessels in the Treatment 2 patients achieved control group values. Despite an immediate increase in perfusion measurements after surgical treatment, their values in a month were still lower than in the control group.Conclusions. In the patients with epiretinal membrane and macular ruptures, a statistically significant decrease in both vascular and perfusion densities of the surface capillary complex was revealed by OCTA. The effects of vitreoretinal surgery performed on Treatment 1 and 2 patients with macula traction pathology included increased visual acuity, decreased retinal thickness, and restoration of the proper vitreoretinal profile. Based on OCTA results, we discovered a gradual increase in vascular density of the macula in Treatment 1 and 2 patients after surgical treatment of VMT syndrome. Retinal perfusion in the macular region of Treatment 1 patients achieved the values of the control group within a month, while in Treatment 2 patients they increased, but remained lower than in control group. OCTA is a highly informative method for the diagnostics and monitoring of the eye posterior segment condition in the patients with VMT syndrome.

scholarly journals Relationships of Rheumatoid Factor with Thickness of Retina and Choroid in Subjects without Ocular Symptoms Using Swept-Source Optical Coherence Tomography

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Qingjian Li ◽  
Yiwen Qian ◽  
Sennan Xu ◽  
Minjie Zhang ◽  
Xu Liang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Rheumatoid Factor ◽  
Choroidal Thickness ◽  
Retinal Thickness ◽  
Statistical Significance ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Swept Source ◽  
Ocular Symptoms ◽  
Significant Difference

Purpose. Researches have confirmed that the retinal and choroidal thickness in patients with autoimmune disease-associated uveitis displays significant changes. However, the relationships between rheumatoid factor (RF) and thickness of the retina and choroid in individuals without ocular manifestations remain unclear. The aim of this study is to assess the associations of RF with retinal and choroidal thickness. Methods. The individuals enrolled in the cross-sectional research received full ocular examinations. The participants were classified as the RF (+) group ( RF ≥ 15.0  IU/ml) and the RF (−) group ( RF < 15.0  IU/ml) according to the serum RF titers. The thickness of the retina and choroid was measured by swept-source optical coherence tomography (SS-OCT). Results. The study covered 65 right eyes of 65 individuals that are RF-positive and 130 right eyes of 130 age- and sex-matched individuals that are RF-negative. The RF (+) group showed decreased choroidal thickness that achieved statistical significance only in the outer inferior and outer temporal sectors, as compared to the RF (−) group. There was no statistically significant difference regarding the retinal thickness between the two groups. Pearson’s correlation analysis revealed that the RF was significantly negatively related to the choroidal thickness in all areas. However, there was no significant correlation between the RF and the retinal thickness. Conclusions. Serum RF titers are closely linked with choroidal thickness before the emergence of ocular symptoms. Research into the relationships may improve our understanding of the role of serum RF in the pathogenesis of uveitis.

scholarly journals Retinal and Choroidal Thickness in relation to C-Reactive Protein on Swept-Source Optical Coherence Tomography

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Dawei Fang ◽  
Qingjian Li ◽  
Ke Yan ◽  
Sennan Xu ◽  
Jing Jiang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Choroidal Thickness ◽  
Retinal Thickness ◽  
Cross Sectional Study ◽  
Optical Coherence ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Swept Source ◽  
Reactive Protein ◽  
Significant Difference

Purpose. To evaluate the relationships between C-reactive protein (CRP) and retinal and choroidal thickness by swept-source optical coherence tomography (SS-OCT). Methods. The participants included in the prospective cross-sectional study underwent a comprehensive ophthalmic examination. Based on the CRP values, the subjects were divided into the CRP (+) group ( CRP ≥ 8.2  mg/L) and the CRP (−) group ( CRP < 8.2  mg/L). The retinal and choroidal thickness was compared between the two groups. Results. This study enrolled 43 right eyes of 43 subjects from the CRP (+) group and 86 right eyes of 86 gender- and age-match subjects from the CRP (−) group. The choroidal thickness in the CRP (+) group was thinner than that in the CRP (−) group except for the outer nasal sector of the Early Treatment Diabetic Retinopathy Study (ETDRS) grid. However, the retinal thickness only in the inner temporal sector showed a significant difference. According to Pearson’s correlation analysis, the CRP was significantly negatively correlated with the choroidal thickness in all sectors and the retinal thickness only in the inner temporal and outer nasal sectors of the ETDRS grid. Conclusion. CRP levels are associated with retinal and choroidal thickness. The data related to the retinal and choroidal thickness changes may help understand the pathogenesis of specific ocular abnormalities in patients with systemic inflammation.

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