Diabetic Retinopathy Detection at Early Stage Using a Set of Morphological Operations

2021 ◽  
pp. 467-478
Author(s):  
N. Ramakrishna ◽  
Vinayadatt V. Kohir
Keyword(s):  
Diabetic Retinopathy ◽  
Early Stage ◽  
Morphological Operations

scholarly journals Detection and Classification of Early Stage Lesions in Diabetic Retinopathy using Color Fundus Images

2019 ◽  
Vol 8 (3) ◽  
pp. 4476-4480
Keyword(s):  
Diabetic Retinopathy ◽  
Clustering Algorithm ◽  
Early Stage ◽  
High Sensitivity ◽  
Morphological Operations ◽  
Hybrid Features ◽  
Speeded Up Robust Features ◽  
Fuzzy C Means Clustering ◽  
Color Fundus Images

Detection of lesions and classification of Diabetic Retinopathy (DR) play an important role in day-to-day life. In this proposed system, colour fundus image is pre-processed using morphological operations to recover from noises and it is converted into HSV colorspace. Fuzzy C-Means Clustering algorithm (FCMC) is used for segmenting the early stage lesions such as Microaneurysms (Ma), Haemorrhages (HE) and Exudates. Hybrid features such as colour correlogram and speeded up robust features (surf) are extracted to train the classifier. Cascaded Rotation Forest (CRF) classifier is used for classification of diabetic retinopathy. The proposed system increases the accuracy of detection and it has got high sensitivity.

scholarly journals Classification of Diabetic Retinopathy Features using Bag of Feature Model

2019 ◽  
Vol 9 (1) ◽  
pp. 381-385
Keyword(s):  
Diabetic Retinopathy ◽  
Blood Vessels ◽  
Early Stage ◽  
Medical Image Analysis ◽  
Feature Learning ◽  
Initial Step ◽  
Feature Model ◽  
Automated System ◽  
Morphological Operations ◽  
Speeded Up Robust Features

Deep learning (DL) as well as feature learning by unsupervised methods have made tremendous consideration in the past decades because of its great and dynamic capacity to change input data into high level depictions by means of various machine learning (ML) methods and approaches. Therefore these interests have also showed a fast and steady growth in the arena of medical image analysis, especially in Diabetic Retinopathy (DR) classification. On contradiction, manual interpretation involves excessive processing time, large amount of expertise and work. Sternness of the DR is analyzed relative to the existence of Microaneurysms (MAs), Exudates (EXs) and Hemorrhages(HEs). Spotting of DR in its early stage is crucial and important to avoid blindness. This paper proposes an algorithm to build an automated system to extract the above mentioned DR features which are the elemental and initial signs of diabetic retinopathy. Initial step in this algorithm is preprocessing of the original image. The next step in this features extraction algorithms is elimination of optic disc (OD) and blood vessels which have similar characteristic with these features. Blood vessels are segmented using Multi-Level Adaptive Thresholding. OD is segmented using morphological operations. Feature extraction and classification is achieved by using deep Bag of Feature (BoF) model which uses Speeded Up Robust Features Our method achieved 100% acuuracy in DRIVE database and over 90% accuracy for e-OPTHA database. Thus, the proposed methodology represents a track towards precise and highly automated DR diagnosis on a large substantial scale along with better sensitivity and specificity.

Review of Various Tasks Performed in the Preprocessing Phase of a Diabetic Retinopathy Diagnosis System

2020 ◽  
Vol 16 (4) ◽  
pp. 397-426
Author(s):  
Muhammad Nadeem Ashraf ◽  
Muhammad Hussain ◽  
Zulfiqar Habib
Keyword(s):  
Diabetic Retinopathy ◽  
Blood Vessels ◽  
Early Stage ◽  
Spherical Shape ◽  
Cost Effective ◽  
Lesion Detection ◽  
Diabetic Patients ◽  
Cad System ◽  
Non Invasive ◽  
Optic Discs

Diabetic Retinopathy (DR) is a major cause of blindness in diabetic patients. The increasing population of diabetic patients and difficulty to diagnose it at an early stage are limiting the screening capabilities of manual diagnosis by ophthalmologists. Color fundus images are widely used to detect DR lesions due to their comfortable, cost-effective and non-invasive acquisition procedure. Computer Aided Diagnosis (CAD) of DR based on these images can assist ophthalmologists and help in saving many sight years of diabetic patients. In a CAD system, preprocessing is a crucial phase, which significantly affects its performance. Commonly used preprocessing operations are the enhancement of poor contrast, balancing the illumination imbalance due to the spherical shape of a retina, noise reduction, image resizing to support multi-resolution, color normalization, extraction of a field of view (FOV), etc. Also, the presence of blood vessels and optic discs makes the lesion detection more challenging because these two artifacts exhibit specific attributes, which are similar to those of DR lesions. Preprocessing operations can be broadly divided into three categories: 1) fixing the native defects, 2) segmentation of blood vessels, and 3) localization and segmentation of optic discs. This paper presents a review of the state-of-the-art preprocessing techniques related to three categories of operations, highlighting their significant aspects and limitations. The survey is concluded with the most effective preprocessing methods, which have been shown to improve the accuracy and efficiency of the CAD systems.

Two-Tier Grading System for NPDR Severities of Diabetic Retinopathy in Retinal Fundus Images

2020 ◽  
Vol 14 ◽  
Author(s):  
Charu Bhardwaj ◽  
Shruti Jain ◽  
Meenakshi Sood
Keyword(s):  
Diabetic Retinopathy ◽  
Statistical Analysis ◽  
Early Stage ◽  
Image Feature ◽  
Grading System ◽  
Fundus Images ◽  
Fundus Image ◽  
Retinal Fundus Images ◽  
Retinal Fundus ◽  
Timely Treatment

: Diabetic Retinopathy is the leading cause of vision impairment and its early stage diagnosis relies on regular monitoring and timely treatment for anomalies exhibiting subtle distinction among different severity grades. The existing Diabetic Retinopathy (DR) detection approaches are subjective, laborious and time consuming which can only be carried out by skilled professionals. All the patents related to DR detection and diagnoses applicable for our research problem were revised by the authors. The major limitation in classification of severities lies in poor discrimination between actual lesions, background noise and other anatomical structures. A robust and computationally efficient Two-Tier DR (2TDR) grading system is proposed in this paper to categorize various DR severities (mild, moderate and severe) present in retinal fundus images. In the proposed 2TDR grading system, input fundus image is subjected to background segmentation and the foreground fundus image is used for anomaly identification followed by GLCM feature extraction forming an image feature set. The novelty of our model lies in the exhaustive statistical analysis of extracted feature set to obtain optimal reduced image feature set employed further for classification. Classification outcomes are obtained for both extracted as well as reduced feature set to validate the significance of statistical analysis in severity classification and grading. For single tier classification stage, the proposed system achieves an overall accuracy of 100% by k- Nearest Neighbour (kNN) and Artificial Neural Network (ANN) classifier. In second tier classification stage an overall accuracy of 95.3% with kNN and 98.0% with ANN is achieved for all stages utilizing optimal reduced feature set. 2TDR system demonstrates overall improvement in classification performance by 2% and 6% for kNN and ANN respectively after feature set reduction, and also outperforms the accuracy obtained by other state of the art methods when applied to the MESSIDOR dataset. This application oriented work aids in accurate DR classification for effective diagnosis and timely treatment of severe retinal ailment.

scholarly journals UNRAVELLING DIABETIC RETINOPATHY THROUGH IMAGE PROCESSING, NEURAL NETWORKS AND FUZZY LOGIC – A REVIEW

2017 ◽  
Vol 10 (4) ◽  
pp. 32
Author(s):  
Srinivasan A ◽  
Sudha S
Keyword(s):  
Image Processing ◽  
Fuzzy Logic ◽  
Diabetic Retinopathy ◽  
Characteristic Curve ◽  
Area Under The Curve ◽  
Computation Time ◽  
Automated System ◽  
Morphological Operations ◽  
Advanced Stage ◽  
Sensitivity Specificity

One of the main causes of blindness is diabetic retinopathy (DR) and it may affect people of any ages. In these days, both young and old ages are affected by diabetes, and the di abetes is the main cause of DR. Hence, it is necessary to have an automated system with good accuracy and less computation time to diagnose and treat DR, and the automated system can simplify the work of ophthalmologists. The objective is to present an overview of various works recently in detecting and segmenting the various lesions of DR. Papers were categorized based on the diagnosing tools and the methods used for detecting early and advanced stage lesions. The early lesions of DR are microaneurysms, hemorrhages, exudates, and cotton wool spots and in the advanced stage, new and fragile blood vessels can be grown. Results have been evaluated in terms of sensitivity, specificity, accuracy and receiver operating characteristic curve. This paper analyzed the various steps and different algorithms used recently for the detection and classification of DR lesions. A comparison of performances has been made in terms of sensitivity, specificity, area under the curve, and accuracy. Suggestions, future workand the area to be improved were also discussed.Keywords: Diabetic retinopathy, Image processing, Morphological operations, Neural network, Fuzzy logic. 

scholarly journals Low and high grade glioma segmentation in multispectral brain MRI data

2018 ◽  
Vol 10 (1) ◽  
pp. 110-132 ◽  
Author(s):  
László Szilágyi ◽  
David Iclănzan ◽  
Zoltán Kapás ◽  
Zsófia Szabó ◽  
Ágnes Győrfi ◽  
...  
Keyword(s):  
Early Stage ◽  
Brain Mri ◽  
High Grade Glioma ◽  
Detection Algorithm ◽  
Gabor Wavelet ◽  
Low Grade ◽  
Data Sets ◽  
Morphological Operations ◽  
High Grade ◽  
Mass Screening System

Abstract Several hundreds of thousand humans are diagnosed with brain cancer every year, and the majority dies within the next two years. The chances of survival could be easiest improved by early diagnosis. This is why there is a strong need for reliable algorithms that can detect the presence of gliomas in their early stage. While an automatic tumor detection algorithm can support a mass screening system, the precise segmentation of the tumor can assist medical staff at therapy planning and patient monitoring. This paper presents a random forest based procedure trained to segment gliomas in multispectral volumetric MRI records. Beside the four observed features, the proposed solution uses 100 further features extracted via morphological operations and Gabor wavelet filtering. A neighborhood-based post-processing was designed to regularize and improve the output of the classifier. The proposed algorithm was trained and tested separately with the 54 low-grade and 220 high-grade tumor volumes of the MICCAI BRATS 2016 training database. For both data sets, the achieved accuracy is characterized by an overall mean Dice score > 83%, sensitivity > 85%, and specificity > 98%. The proposed method is likely to detect all gliomas larger than 10 mL.

scholarly journals Machine Learning for Diabetic Retinopathy Detection using Image Processing

2021 ◽  
Vol 9 (5) ◽  
pp. 209-215
Author(s):  
Ujwala W. Wasekar ◽  
R. K. Bathla
Keyword(s):  
Image Processing ◽  
Diabetic Retinopathy ◽  
Early Stage ◽  
Haar Wavelet ◽  
Feature Analysis ◽  
Median Filtering ◽  
Wavelet Filters ◽  
Knn Classifier ◽  
Form Features ◽  
Processing Techniques

he disorder of Diabetic Retinopathy (DR), a complication of Diabetes that may lead to blindness if not treated at an early stage, is diagnosed by evaluating the retina images of eye. However, the manual grading of images for identifying the seriousness of DR disease requires many resources and it also takes a lot of time. Automated systems give accurate results along with saving time. Ophthalmologists may find it useful in reducing their workload. Proposed work presents the method to correctly identify the lesions and classify DR images efficiently. Blood leaking out of veins form features such as exudates, microaneurysms and haemorrhages, on retina. Image processing techniques assist in DR detection. Median filtering is used on gray scale converted image to reduce noise. The features of the pre-processed images are extracted by textural feature analysis. Optic disc (OD) segmentation methodology is implemented for the removal of OD. Blood vessels are extracted using haar wavelet filters. KNN classifier is applied for classifying retinal image into diseased or healthy .The proposed algorithm is executed in MATLAB software and analyze results with regard to certain parameters such as accuracy, sensitivity, and specificity. The outcomes prove the superiority of the new method with sensitivity of 92.6%, specificity of 87.56% and accuracy of 95% on Diaretdb1 database.

scholarly journals Classification among Microaneurysms, Exudates, and Lesion free Retinal Regions in the Eye Images using Transfer Learned CNNs

2019 ◽  
Vol 9 (2) ◽  
pp. 5508-5512
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Diabetic Retinopathy ◽  
Glucose Level ◽  
Vision Loss ◽  
Early Stage ◽  
Training Data ◽  
Fundus Images ◽  
Diabetic Mellitus ◽  
Start Process

When pancreas fails to secrete sufficient insulin in the human body, the glucose level in blood either becomes too high or too low. This fluctuation in glucose level affects different body organs such as kidney, brain, and eye. When the complications start appearing in the eyes due to Diabetic Mellitus (DM), it is called Diabetic Retinopathy (DR). DR can be categorized in several classes based on the severity, it can be Microaneurysms (ME), Haemorrhages (HE), Hard and Soft Exudates (EX and SE). DR is a slow start process that starts with very mild symptoms, becomes moderate with the time and results in complete vision loss, if not detected on time. Early-stage detection may greatly bolster in vision loss. However, it is impassable to detect the symptoms of DR with naked eyes. Ophthalmologist harbor to the several approaches and algorithm which makes use of different Machine Learning (ML) methods and classifiers to overcome this disease. The burgeoning insistence of Convolutional Neural Network (CNN) and their advancement in extracting features from different fundus images captivate several researchers to strive on it. Transfer Learning (TL) techniques help to use pre-trained CNN on a dataset that has finite training data, especially that in under developing countries. In this work, we propose several CNN architecture along with distinct classifiers which segregate the different lesions (ME and EX) in DR images with very eye-catching accuracies.

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