scholarly journals Epidemiological features of Lumpy skin disease of the large ruminants: Review of literature

2020 ◽  
Vol 6 (4) ◽  
pp. 9-12
Author(s):  
Sh. K. Zeynalova
Keyword(s):  
Skin Disease ◽  
Animal Health ◽  
Biological Properties ◽  
Economic Consequences ◽  
Lumpy Skin Disease ◽  
Urgent Task ◽  
The World ◽  
Spread Of Infection ◽  
Short Time ◽  
World Organisation

Lumpy skin disease (LSD) is an infectious disease in cattle, characterized by nodules on the surface of the skin and which can have serious economic consequences. Starting from 2014, new outbreaks of LSD in the world and its spread to Central Asia and the Middle East are noted. Due to the huge economic impact on the economy, the World Organisation for Animal Health (OIE) has classified LSD as a particularly dangerous disease that needs to be notified. The analysis of the literature on LSD shows that many issues remain unstudied and require appropriate research to be carried out. In connection with the difficult epizootic situation and the threat of further spread of the virus, the urgent task is the study of biological properties of the causative agent with a view of development the specific prophylactic agents that would allow to prevent the spread of infection in a short time

scholarly journals Development of a Safe and Highly Efficient Inactivated Vaccine Candidate against Lumpy Skin Disease Virus

Vaccines ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 4
Author(s):  
Janika Wolff ◽  
Tom Moritz ◽  
Kore Schlottau ◽  
Donata Hoffmann ◽  
Martin Beer ◽  
...  
Keyword(s):  
Skin Disease ◽  
Animal Health ◽  
Vaccine Virus ◽  
Lumpy Skin Disease ◽  
Virus Shedding ◽  
Clinical Protection ◽  
Inactivated Vaccines ◽  
Disease Free ◽  
World Organisation ◽  
Free Status

Capripox virus (CaPV)-induced diseases (lumpy skin disease, sheeppox, goatpox) are described as the most serious pox diseases of livestock animals, and therefore are listed as notifiable diseases under guidelines of the World Organisation for Animal Health (OIE). Until now, only live-attenuated vaccines are commercially available for the control of CaPV. Due to numerous potential problems after vaccination (e.g., loss of the disease-free status of the respective country, the possibility of vaccine virus shedding and transmission as well as the risk of recombination with field strains during natural outbreaks), the use of these vaccines must be considered carefully and is not recommended in CaPV-free countries. Therefore, innocuous and efficacious inactivated vaccines against CaPV would provide a great tool for control of these diseases. Unfortunately, most inactivated Capripox vaccines were reported as insufficient and protection seemed to be only short-lived. Nevertheless, a few studies dealing with inactivated vaccines against CaPV are published, giving evidence for good clinical protection against CaPV-infections. In our studies, a low molecular weight copolymer-adjuvanted vaccine formulation was able to induce sterile immunity in the respective animals after severe challenge infection. Our findings strongly support the possibility of useful inactivated vaccines against CaPV-infections, and indicate a marked impact of the chosen adjuvant for the level of protection.

Risk analysis of lumpy skin disease in Turkey

2016 ◽  
Author(s):  
Ömer Baris Ince ◽  
Serkan Çakir ◽  
Mehmet Ali Dereli
Keyword(s):  
Risk Analysis ◽  
Skin Disease ◽  
Control Strategies ◽  
Animal Health ◽  
Economic Loss ◽  
Control Measures ◽  
Lumpy Skin Disease ◽  
The World ◽  
Potential Risks ◽  
And Control

Lumpy Skin Disease (LSD) in Turkish cattle appeared suddenly two years ago. This study evaluates potential risks of LSD and recommends appropriate control measures. The World Animal Health Organization’s protocol was used for the risk analysis. Likelihoods for disease release and exposure were estimated with a qualitative scale ranging from negligible to high. Outbreaks were recorded in nine provinces in Turkey. Total economic loss due to the disease was estimated to be $241.903.500 US dollars. The risk analysis suggests a greater than negligible risk. Therefore, disease prevention and control strategies should be considered by the Turkish Veterinary Authority.

scholarly journals Diseases of Gastropoda

2022 ◽  
Vol 12 ◽  
Author(s):  
Michelle F. O’Brien ◽  
Sarah Pellett
Keyword(s):  
Fresh Water ◽  
Food Source ◽  
Negative Impact ◽  
Animal Health ◽  
Etiological Agent ◽  
Human Consumption ◽  
Intermediate Hosts ◽  
The World ◽  
Herpesvirus 1 ◽  
World Organisation

Gastropods (class Gastropoda) form the largest of the classes in the phylum Mollusca and inhabit terrestrial, fresh water and marine environments. A large number of these species are of major conservation importance and are an essential component of ecosystems. Gastropods may be deemed as pests, having a negative impact in horticulture and agriculture, whereas others may be used as a food source for human consumption and therefore are beneficial. Gastropods are susceptible to primary diseases and also act as intermediate hosts for diseases which affect other animals, including humans. The diseases described include two that are notifiable to the World Organisation for Animal Health (OIE): Xenohaliotis californiensis and Abalone viral ganglioneuritis caused by Haliotid herpesvirus-1 (HaHV-1). Research into the diseases of gastropods has often focused on those species that act as intermediate disease hosts, those that are used in research or those cultured for food. In this paper we review the viral, bacterial, fungal, parasitic and miscellaneous conditions that have been reported in gastropods and mention some of the factors that appear to predispose them to disease. The pathogenicity of a number of these conditions has not been fully ascertained and more research is needed into specifying both the etiological agent and significance in some of the diseases reported.

scholarly journals Characterization of a Nigerian Lumpy Skin Disease Virus Isolate after Experimental Infection of Cattle

Pathogens ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 16
Author(s):  
Janika Wolff ◽  
Eeva Tuppurainen ◽  
Adeyinka Adedeji ◽  
Clement Meseko ◽  
Olayinka Asala ◽  
...  
Keyword(s):  
Disease Virus ◽  
Experimental Infection ◽  
Skin Disease ◽  
Clinical Course ◽  
Animal Health ◽  
Trade Restrictions ◽  
Skin Sample ◽  
Lumpy Skin Disease ◽  
Lumpy Skin Disease Virus ◽  
Large Ruminant

Lumpy skin disease virus (LSDV), together with sheeppox virus and goatpox virus, belong to the genus Capripoxvirus within the family Poxviridae. Collectively, they are considered the most serious poxvirus diseases of agricultural livestock. Due to their severe clinical course and consequent loss of production, as well as high mortality of naïve small and large ruminant populations, they are known to have a significant impact on the economy and global trade restrictions of affected countries. Therefore, all capripox diseases are classified as notifiable under the guidelines of the World Organization of Animal Health (OIE). Since the 1970s, several outbreaks of LSD have been recorded in Nigeria. Until now, only a little information on the virus strains leading to the reported outbreaks have been published, dealing mainly with the phylogenetic relationship of those strains and the description of field outbreaks. During the present study, we experimentally infected cattle with a low-passage Nigerian LSDV strain isolated from a skin sample of LSD positive cattle in Nigeria in 2018. Clinical, molecular and serological data indicate that this LSDV isolate is highly pathogenic in cattle since it induced a severe clinical course and approximately 33% mortality in naïve Holstein Friesian cattle after experimental infection.

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