ASSOCIATION OF NEONATAL SEIZURES WITH SPECIAL REFERENCE TO BIOCHEMICAL PARAMETERS

2021 ◽  
pp. 18-20
Author(s):  
Krushna Chandra Das Chandra Das ◽  
Debarshi Jana
Keyword(s):  
Observational Study ◽  
Special Reference ◽  
Biochemical Parameters ◽  
West Bengal ◽  
Hospital Setting ◽  
Signs And Symptoms ◽  
Neonatal Seizures ◽  
Study Association ◽  
One Year

AIM: To identify co relation between biological changes and neonatal seizures and the relation between neonatal seizures and infection. MATERIAL AND METHOD: It is a descriptive observational study in hospital setting. The study is to be st st conducted at SNCU of SSKM HOSPITAL, WEST BENGAL over one year; from 1 March 2018 to 1 March 2019. Children aged 0 days to 28 days admitted in Pediatric SNCU with signs and symptoms suggestive of seizure during the period of study was constitute the population under study. Association of hypoglycemia vs. outcome was statistically signic RESULT: ant (p=0.0017) and Association of hypocalcemia vs. outcome was statistically signicant (p=0.0084). We found that hypoglycaemia was more com CONCLUSION: mon in 1 day of age which was statistically signicant.

Prospective analysis of incidence, extent and chronicity of lower extremity venous thrombosis

2012 ◽  
Vol 29 (1) ◽  
pp. 37-42 ◽  
Author(s):  
K P Poulikidis ◽  
A P Gasparis ◽  
N Labropoulos
Keyword(s):  
Lower Extremity ◽  
Venous Thrombosis ◽  
Hospital Setting ◽  
Signs And Symptoms ◽  
University Hospital ◽  
Recurrent Thrombosis ◽  
Acute Thrombosis ◽  
Left Limb ◽  
Hospital Patients ◽  
One Year

Objective This study was designed to determine all variables related to lower extremity deep venous thrombosis (DVT) to be used as reference in patients examined in a hospital setting. Methods Consecutive patients presented with signs and symptoms of venous thromboembolism over a one-year period, examined in our university hospital. Patients’ demographics and clinical characteristics in a data base organized to answer all the pertinent questions. Results There were 2594 patients. Thrombosis was found in 348 (13.4%) of which 249 were acute and 72 had chronic luminal changes. Unilateral thrombosis was found in 268 and bilateral in 80. Acute DVT and/or chronic changes were more common on the left limb. Chronic thrombosis was more prevalent in the proximal veins. Acute thrombosis was more often found in the inpatients. Both acute DVT and chronic changes were found in 27 patients (7.8%) of whom 15 were bilateral. Conclusions Various patterns of thrombosis are found in both inpatients and outpatients with the former having a higher incidence of acute events. Acute, chronic and recurrent thrombosis are very frequent and very important to report as they could change the management of the patients.

Marketing and Sickness in Micro and Small Enterprises in India: An Inter-State Analysis with Special Reference to the Engineering Enterprises in the District of Howrah, West Bengal

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Manidipa Dasgupta
Keyword(s):  
Special Reference ◽  
West Bengal ◽  
Small Scale ◽  
Small Enterprises ◽  
Related Area ◽  
Micro And Small Enterprises ◽  
Economic Advancement ◽  
Small Scale Industries ◽  
Inter State ◽  
State Analysis

Micro and Small Enterprises (MSEs) [formerly Tiny and Small Scale Industries (SSIs)] are recognized as the main contributors in socio-economic advancement of any country especially the developing one like India. But due to some controllable and/or uncontrollable factors, MSEs cannot get themselves free from sickness. Sickness in MSEs expands its steps in all states in India amongst which West Bengal (WB) is specially notable mainly due to the continuous degradation of Micro and Small Engineering Enterprises of the then Birmingham/Sheffield of the East, Howrah. In WB, Howrah is considered to be the most incipient sickness-prone district for MSEs. Government effort to locate the probable causes of sickness of MSEs has exposed that in India, lack of demand of the product of MSEs in market is the most sever one, while in WB, marketing problem holds the maximum severity, followed by lack of demand which is also partially due to the marketing problem. The present paper aims at identifying how far the major responsible causes in marketing related area are liable in bringing about sickness in Micro and Small Engineering Enterprises.

scholarly journals Pharmacological and clinical evaluation of deferasirox formulations for treatment tailoring

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Andrea Piolatto ◽  
Paola Berchialla ◽  
Sarah Allegra ◽  
Silvia De Francia ◽  
Giovanni Battista Ferrero ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Renal Impairment ◽  
Observational Study ◽  
Iron Overload ◽  
Iron Loading ◽  
Comprehensive Comparison ◽  
Dispersible Tablets ◽  
One Year ◽  
Safety Features

AbstractDeferasirox (DFX) is the newest among three different chelators available to treat iron overload in iron-loading anaemias, firstly released as Dispersible Tablets (DT) and more recently replaced by Film-Coated Tablets (FCT). In this retrospective observational study, pharmacokinetics, pharmacodynamics, and safety features of DFX treatment were analyzed in 74 patients that took both formulations subsequently under clinical practice conditions. Bioavailability of DFX FCT compared to DT resulted higher than expected [Cmax: 99.5 (FCT) and 69.7 (DT) μMol/L; AUC: 1278 (FCT) and 846 (DT), P < 0.0001]. DFX FCT was also superior in scalability among doses. After one year of treatment for each formulation, no differences were observed between the treatments in the overall iron overload levels; however, DFX FCT but not DT showed a significant dose–response correlation [Spearman r (dose-serum ferritin variation): − 0.54, P < 0.0001]. Despite being administered at different dosages, the long-term safety profile was not different between formulations: a significant increase in renal impairment risk was observed for both treatments and it was reversible under strict monitoring (P < 0.002). Altogether, these data constitute a comprehensive comparison of DFX formulations in thalassaemia and other iron-loading anaemias, confirming the effectiveness and safety characteristics of DFX and its applicability for treatment tailoring.

scholarly journals A Mental Health Drop-In Centre Offering Brief Transdiagnostic Psychological Assessment and Treatment in a Paediatric Hospital Setting: A One-Year Descriptive Study

2021 ◽  
Vol 18 (10) ◽  
pp. 5369
Author(s):  
Matteo Catanzano ◽  
Sophie D Bennett ◽  
Marc S Tibber ◽  
Anna E Coughtrey ◽  
Holan Liang ◽  
...  
Keyword(s):  
Mental Health ◽  
Young People ◽  
Psychological Assessment ◽  
Mental Health Problems ◽  
Hospital Setting ◽  
Considerable Proportion ◽  
Paediatric Hospital ◽  
Cognitive Behaviour ◽  
Assessment And Treatment ◽  
One Year

Aim: This study was part of a broader project to examine the acceptability, feasibility and impact of a transdiagnostic mental health drop-in centre offering brief psychological assessment and treatment for children and young people and/or their families with mental health needs in the context of long-term physical health conditions (LTCs). The aims of this investigation were to characterise: (i) the use of such a centre, (ii) the demographics and symptoms of those presenting to the centre, and (iii) the types of support that are requested and/or indicated. Methods: A mental health “booth” was located in reception of a national paediatric hospital over one year. Characteristics of young people with LTCs and their siblings/parents attending the booth were defined. Emotional/behavioural symptoms were measured using standardised questionnaires including the Strengths and Difficulties Questionnaire (SDQ). Participants subsequently received one of four categories of intervention: brief transdiagnostic cognitive behaviour therapy (CBT), referral to other services, neurodevelopmental assessment or signposting to resources. Results: One hundred and twenty-eight participants were recruited. The mean age of young people was 9.14 years (standard deviation: 4.28); 61% identified as white and 45% were male. Over half of young people recruited scored in the clinical range with respect to the SDQ. Presenting problems included: anxiety (49%), challenging behaviour (35%), low mood (22%) and other (15%). Conclusions: A considerable proportion of young people with LTC in a paediatric hospital scored in the clinical range for common mental health problems, indicating a potential for psychological interventions.

scholarly journals 2054. Hospital-initiated Antibiotics in Nursing Homes

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S692-S692
Author(s):  
Jon P Furuno ◽  
Brie N Noble ◽  
Vicki Nordby ◽  
Bo Weber ◽  
Jessina C McGregor ◽  
...  
Keyword(s):  
Nursing Homes ◽  
Hospital Setting ◽  
Antibiotic Prescribing ◽  
Administration Route ◽  
Electronic Health Record Data ◽  
For Profit ◽  
Duration Of Therapy ◽  
Record Data ◽  
One Year ◽  
The One

Abstract Background Nursing homes (NHs) are required by the Centers for Medicare and Medicaid Services to maintain antimicrobial stewardship programs. Hospital-initiated antibiotics may pose a barrier to optimizing antibiotic prescribing in this setting. Our objective was to characterize hospital-initiated antibiotic prescriptions among NH residents. Methods We collected electronic health record data on antibiotic prescribing events within 60 days of residents’ admission to 17 for-profit NHs in Oregon, California, and Nevada between January 1, and December 31, 2017. We characterized antibiotics prescribed, administration route, and proportion initiated in a hospital setting. Results Over the one-year study period, there were 4350 antibiotic prescribing events among 1633 NH residents. Mean (standard deviation) age was 77 (12) years and 58% were female. Approximately 45% (1,973/4,350) of antibiotics prescribed within 60 days of NH admission were hospital-initiated. The most frequently prescribed hospital-initiated antibiotics were cephalosporins (27%; 1st gen: 54%, 2nd gen: 6%, 3rd gen: 34%, 4th gen: 5%, 5th gen: 1%), fluoroquinolones (20%), and penicillins (14%; natural penicilins: 4%, semisynthetic penicillins: 3%, aminopenicillans: 57%, β-lactam/β-lactamase inhibitors: 21%, and antipseudomonal penicillins: 15%). Additionally, 24% of antibiotics were parenteral and the median (interquartile range) duration of therapy was 6 (3–10) days. Over 15% of residents with hospital-initiated antibiotics were readmitted to the hospital within 30 days. Conclusion Approximately 45% of antibiotic prescribing in a multistate sample of NHs were hospital-initiated, of which roughly 40% was broad-spectrum. Interventions specifically targeting antibiotic prescribing during and following the transition from hospitals to NHs are needed. Disclosures All authors: No reported disclosures.

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