UTILITY OF FNAC AS A DIAGNOSTIC TOOL IN HEAD AND NECK SWELLINGS

2021 ◽  
pp. 30-33
Author(s):  
Akhil Nadesan ◽  
Aparna M. Kulkarni ◽  
Rajendra B. Madane
Keyword(s):  
Head And Neck ◽  
Diagnostic Tool ◽  
Cost Effective ◽  
Clinical History ◽  
Excisional Biopsy ◽  
Needle Aspiration ◽  
Minimal Risk ◽  
Accuracy Rate ◽  
Female Ratio ◽  
Neoplastic Lesion

Head and neck lesions encompass a multitude of congenital, inammatory or neoplastic lesions including several anatomic sites and originating in different tissues and organs. Fine needle aspiration cytology (FNAC) is a simple, quick, feasible, cost effective and repeatable outpatient procedure with minimal risk of complication. The study included 407 patients presented with palpable head and neck swelling in Department of Pathology RCSM GMC, Kolhapur from November 2016 to January 2018. Detailed clinical history of patient was noted. Aspirations were done by using 10 ml syringe and 22/23 gauge needles. Smears were stained with PAP, Haematoxylin and eosin and Leishman stain. Cyto-histopathological correlations were done wherever possible. Results: Out of 407 patients of head and neck lesions studied, lymph node 48.16%, was the predominant site aspirated with reactive lymphadenitis being the commonest lesion. Thyroid lesions constituted 32.68%, followed by soft tissue and miscellaneous 14.25% and salivary gland 4.91%. In our study females predominated with male to female ratio 1:1.7 . Overall accuracy rate of FNAC was 96.33% with sensitivity 93.10%, specicity 97.5% and positive predictive value of 93.10%. Conclusion: Though excisional biopsy is the gold standard for diagnosis of head and neck neoplastic lesion. FNAC is a rapid, cheap diagnostic tool now-a-days with overall accuracy rate of more than 90%.

scholarly journals Study of Cytodiagnosis of Head and Neck Neoplastic Lesions and Comparison with Histopathology

2013 ◽  
Vol 4 (3) ◽  
pp. 119-122
Author(s):  
Maniyar U Amit ◽  
Harshid Laxmanbhai Patel ◽  
BH Parmar
Keyword(s):  
Head And Neck ◽  
Frozen Section ◽  
Excisional Biopsy ◽  
Needle Aspiration ◽  
Histopathological Diagnosis ◽  
Age Group ◽  
Aspiration Cytology ◽  
Female Ratio ◽  
Neoplastic Lesion ◽  
Neoplastic Lesions

ABSTRACT Introduction The development of aspiration cytology is one of the biggest advances in anatomic pathology. Cancer has become one of the 10 leading causes of death in India. Head and neck neoplasia is a major form of cancer in India, accounting for 23% of all cancers in males and 6% in females. The advantages of fine needle aspiration cytology (FNAC) are: it is safe, sensitive and specific for the diagnosis of malignancy, gives a rapid report, requires little equipment, causes minimal discomfort to the patient, is an out patient procedure, repeatable and cost effective avoids the use of frozen section, reduces the rate of exploratory procedures and allows a definitive diagnosis of inoperable cases. FNAC is of particular relevance in head and neck lesions because of easy assessibility, excellent patient compliance, minimally invasive nature of procedure and helping to avoid surgery in non-neoplastic lesions, inflammatory conditions and also some tumors. Aims and objectives To test the utility of FNAC, to establish the diagnostic accuracy of cytology by comparison with histopathology diagnosis and to establish the sensitivity and specificity of this technique in head and neck neoplastic lesion. Materials and methods The present study was undertaken in the Department of Pathology, Government Medical College and Hospital, Nashik, between January 2008 and June 2009. Results In the present study, maximum number of aspirates from head and neck neoplastic lesions were found to be of lymph nodes (56.37%). Of the total 378 cases, 71.69% were malignant. 6th decade was the most common age group affected (26.46%). Mean age group was found to be 45.84 years. Males were more commonly affected (65.34%). The male to female ratio was 1.8:1. Out of 92 cases available for follow-up, 85.87% of the cases were same as histopathological diagnosis. Summary and conclusion Excisional biopsy remains the gold standard for diagnosis of head and neck neoplastic lesion, cytological study can establish the diagnosis of the majority of head and neck neoplastic lesions and can be recommended as an adjunct to histopathology. How to cite this article Amit MU, Patel HL, Parmar BH. Study of Cytodiagnosis of Head and Neck Neoplastic Lesions and Comparison with Histopathology. Int J Head Neck Surg 2013; 4(3):119-122.

CYTOPATHOLOGICAL SPECTRUM OF FNAC IN PALPABLE HEAD AND NECK LESIONS

2021 ◽  
pp. 53-54
Author(s):  
Devendu Bose ◽  
Bejoy Chand Banerjee
Keyword(s):  
Salivary Gland ◽  
Lymph Node ◽  
Soft Tissue ◽  
Head And Neck ◽  
Clinical History ◽  
Needle Aspiration ◽  
Minimal Risk ◽  
Neck Swelling ◽  
Neck Masses ◽  
Common Diagnosis

Introduction: Head and neck lesions comprises a large number of congenital, inammatory or neoplastic lesions including different anatomic sites and originating in different tissues and organs. Fine needle aspiration cytology (FNAC) is a simple, quick, feasible, repeatable and outpatient procedure with minimal risk of complication. Aim: To study the role of FNAC and its utility in diagnosis of palpable head neck masses and to determine the spectrum of various lesions. Materials And Methods: A retrospective study was conducted in pathology department of Shaheed Nirmal Mahato Medical College, Dhanbad, Jharkhand from January 2016 to December 2020 on patients with palpable head and neck swelling. Detailed clinical history of patient was noted. Aspirations were done by using 10 ml syringe and 22/23 gauge needles. Smears were stained with PAP, Haematoxylin and Eosin and Leishman stain. Cytomorphological diagnosis was given. Results: Out of 562 patients of head and neck swelling, 61.92% (348 cases) were of lymph node, 20.28% (114 cases) were of thyroid, 3.38% from salivary gland (19 cases), 14.06% (79 cases) from skin and soft tissue swellings. The most common diagnosis was reactive lymphadenitis (32.74%) followed by granulomatous lymphadenitis (18.33%). The mean age of study population was 32 years. There was female preponderance (88.59%) in thyroid lesions whereas lymph node lesions (60.91%), salivary gland lesions (73.68%) and soft tissue swellings (59.49%) were more common in males. Conclusion: From our study we concluded that FNAC is simple, quick, inexpensive, repeatable and minimally invasive rst line investigation for differential diagnosis of head and neck lesions.

scholarly journals Diagnosis and Management of Extracranial Head and Neck Schwannomas: A Review of 27 Cases

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Ryuji Yasumatsu ◽  
Torahiko Nakashima ◽  
Rina Miyazaki ◽  
Yuichi Segawa ◽  
Shizuo Komune
Keyword(s):  
Head And Neck ◽  
Postoperative Morbidity ◽  
Tumor Resection ◽  
Clinical History ◽  
Needle Aspiration ◽  
Vagus Nerves ◽  
Surgical Data ◽  
Needle Aspiration Cytology ◽  
Clinical Records ◽  
Complete Tumor

Objectives. Clinical records of 27 patients with extracranial head and neck schwannoma were retrospectively reviewed.Methods. Ultrasonography (US) was performed in all cases. Seven patients underwent CT. Twenty-five patients underwent MRI. Fine needle aspiration cytology (FNAC) was performed for 12 of the 27 patients. Clinical history, surgical data, and postoperative morbidity were analyzed.Results. The images of US showed a well-defined, hypoechoic, primarily homogeneous solid mass. At CT, only one of 7 cases (14%) was able to suggest the diagnosis of schwannoma. At MRI, twenty of 25 cases (80%) suggested the diagnosis of schwannoma. Only three of 12 cases (25%) displayed a specific diagnosis of schwannoma rendered on FNAC. The distribution of 27 nerves of origin was 10 (37%) vagus nerves, 6 (22%) sympathetic trunks, 5 (19%) cervical plexuses, 3 (11%) brachial plexuses, 2 (7%) hypoglossal nerves, and 1 (4%) accessory nerve. Complete tumor resection was performed in 11 patients, and intracapsular enucleation of the tumor was performed in 16 patients. The rate of nerve palsy was 100 (11/11) and 31% (5/16).Conclusions. MRI is sensitive and specific in the diagnosis of schwannoma. Intracapsular enucleation was an effective and feasible method for preserving the neurological functions.

scholarly journals Immunocytochemical Study of Rabbit-Polyclonal to Mycobacterium Tuberculosis, AB905: Improving Diagnostic of Tuberculous Lymphadenitis

2021 ◽  
Vol 21 (2) ◽  
pp. 95-101
Author(s):  
Humairah Medina Liza Lubis ◽  
Emni Purwoningsih ◽  
Ance Roslina ◽  
Muhammad Al Anas
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Predictive Value ◽  
Extrapulmonary Tuberculosis ◽  
Clinical History ◽  
Excisional Biopsy ◽  
Needle Aspiration ◽  
Cross Sectional Study ◽  
Tuberculous Lymphadenitis ◽  
Immunocytochemical Study ◽  
Cross Sectional

Tuberculous lymphadenitis (TBLN) is the most common form of extrapulmonary tuberculosis. However, the optimal diagnosis using Fine-Needle Aspiration Cytology (FNAC) or excisional biopsy is uncertain. This research aims to improve the diagnostic of TBLN with FNAC and immunocytochemistry (ICC) compared to the response to antituberculosis therapy. The cross-sectional study involved 43 patients with the criteria for TBLN diagnosis based on the appropriate clinical history of tuberculosis and indicative cytological results. Immunocytochemical examination employed rabbit-polyclonal to Mycobacterium tuberculosis (MTB) antibody (AB905). The MTB expression was found in 35 out of 43 cases (81%) that appropriate cytological features of the tuberculosis process. Meanwhile, eight out of 43 cases (19%) did not express MTB. Diagnostic tests for lesions with a positive cytologic appearance of TBLN and ICC were compared to the response to anti-tuberculosis therapy, revealing the sensitivity, specificity, positive predictive value, and negative predictive value of 95.2%, 75%, 95.2%, and 17%, respectively. Besides, Fisher's exact tests utilized to identify the relationship between two variables; p 0.05 was considered significant. This research found immunocytochemical study was a sensitive and specific tool for improving the diagnostic of TBLN.

Utility of Fine-Needle Aspiration As a Diagnostic Technique in Lymphoma

2004 ◽  
Vol 22 (15) ◽  
pp. 3046-3052 ◽  
Author(s):  
Sean T. Hehn ◽  
Thomas M. Grogan ◽  
Thomas P. Miller
Keyword(s):  
Fine Needle Aspiration ◽  
Diagnostic Technique ◽  
Cost Effective ◽  
Excisional Biopsy ◽  
Needle Aspiration ◽  
Histologic Diagnosis ◽  
Fine Needle ◽  
Biopsy Diagnosis ◽  
Independent Review ◽  
Relapsed Disease

Purpose To evaluate, from a clinician's perspective, the sensitivity and specificity of fine-needle aspiration (FNA) as a technique for the diagnosis of lymphoma. Patients and Methods Medical records of 470 new patients seen in one lymphoma specialist's clinic from January 1998 through December 2002 were reviewed. Ninety-nine (21%) of the 470 patients underwent a total of 115 FNA procedures, which were assessed by more than 70 different pathologists in 32 different pathology departments. Subsequent excisional biopsies were performed in 67 of these patients and interpreted by a single hematopathology group without independent review. Results Of 115 FNA procedures, 93 were completed for the initial evaluation of lymphoma and 22 were done for assessment of relapsed disease. Of the 93 FNA attempts at initial diagnosis, only 27 (29%) were given a specific and complete histologic diagnosis using an accepted classification system (Working Formulation, Revised European-American Classification of Lymphoid Neoplasms, WHO). For the 22 FNAs done for recurrent disease, only nine (41%) were classified using an accepted system. Sixty-seven (72%) of the 93 FNAs performed for the evaluation of initial disease had subsequent excisional biopsies. Among these paired comparisons, only eight (12%) of 67 FNA diagnoses were correlated with the subsequent excisional biopsy diagnosis. Immunophenotyping was completed on 24 of the 67 paired FNAs. Seven of the 24 FNAs with immunophenotyping (29%) were correlated with subsequent histology on excisional biopsy. Only one (2%) of 43 FNA diagnoses, based on morphology alone, was correlated with subsequent excisional biopsy diagnosis. Conclusion Overall, FNA for lymphoma diagnosis is not helpful, not cost effective, and in addition may misguide treatment.

Head and Neck Lymphoma in Patients with the Acquired Immune Deficiency Syndrome

1992 ◽  
Vol 106 (3) ◽  
pp. 258-260 ◽  
Author(s):  
Aaron L. Shapiro ◽  
Frank G. Shechtman ◽  
Robert A. Guida ◽  
Charles P. Kimmelman
Keyword(s):  
B Cell ◽  
Head And Neck ◽  
Neck Region ◽  
Immune Deficiency Syndrome ◽  
Excisional Biopsy ◽  
Large Cell ◽  
Needle Aspiration ◽  
Deficiency Syndrome ◽  
B Cell Lymphomas ◽  
Supraclavicular Fossa

A marked increase has recently been noted in the incidence of lymphoma in patients with AIDS. These lymphomas are generally high-grade, of B-cell origin, and often involve extranodal sites. Reported here are twenty patients with AIDS in whom symptoms and physical findings developed related to the head and neck region as a result of lymphoma. The tumor was observed in a variety of sites, including the nasopharynx, orbit, submandibular triangle, anterior and posterior cervical triangles, supraclavicular fossa, and the hypopharynx. Sixteen tumors were large cell nonHodgkin's B-cell lymphomas, three were small cell nonHodgkin's B-cell lymphomas, and one was Hodgkin's disease, mixed cellularity. All were treated with combination chemotherapy. A high degree of suspicion for lymphoma is required in treating any patient with AIDS who has a rapidly enlarging mass in the head and neck. If needle aspiration is nondiagnostic, excisional biopsy should be performed after a complete head and neck evaluation. Although the development of lymphoma associated with AIDS portends a grave prognosis, prompt diagnosis will allow an improved chance of remission of the lymphoma.

scholarly journals FNAC: A Simple & Cost-Effective Diagnostic Tool for Benign & Malignant Pathologies Associated with Cervical Lymphadenopathy

2021 ◽  
Vol 35 (4) ◽  
pp. 25-29
Author(s):  
Sohail Anwar
Keyword(s):  
Diagnostic Tool ◽  
Cervical Lymphadenopathy ◽  
Cost Effective ◽  
Needle Aspiration ◽  
P Value ◽  
Invasive Test ◽  
Outpatient Departments ◽  
Metastatic Neoplasm ◽  
Needle Aspiration Cytology ◽  
Age Range

Introduction: Cervical lymphadenopathy is very common as the presenting complaint in our outpatient departments. Its etiology may either be benign or malignant. Fine needle aspiration cytology (FNAC) is a comparatively cheap, easy to perform minimally invasive test. It has become the go to test to determine the cause of lymphadenopathy Aims & Objectives: To determine whether FNAC is a cost-effective diagnostic tool in evaluation of various benign and malignant Pathologies associated with cervical lymphadenopathy. Place and duration of study: It is a retrospective study conducted at Gulab Devi Hospital from April 2019 to April 2021. Material & Methods: The cyto-morphologic features seen in the aspirates were critically analyzed and correlated with their etiology. SPSS version 24.0 was analyzed for data analysis. A p-value of <0.05 was considered significant. Results: Among the 100 patients 56 were females and 44 were males with a female to male ratio of 1.3:1. The age range of the patients was from 3 to 75 years. 37% were reactive lymphadenitis, 32% were tuberculosis, 12% were suppurative, 11% were lymphoproliferative disorders, 8% cases were metastatic neoplasm. Conclusion: FNAC is a reliable and cost effective to diagnose the etiologies of cervical lymphadenopathy.

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