EFFECT OF KIDNEY DISEASE ON THE MORTALITY OF COVID POSITIVE PATIENTS IN A TERTIARY CARE HOSPITAL, INDIA
INTRODUCTION: CKD and kidney failure are signicant comorbidities associated with unfavourable outcomes in patients with COVID-19. Patients with CKD/kidney failure also have a disproportionate burden of other comorbidities 1 (e.g., coronary artery disease, hypertension, and diabetes mellitus) associated with more severe presentations of COVID-19 . SARS-CoV-2 infection frequently triggers a massive release of proinammatory cytokines and may induce coagulation abnormalities that increase the risk of 2 cardiovascular events and multiorgan dysfunction. MATERIALS & METHODS: It is a retrospective study done in government general hospital Vijayawada from patients admitted with covid positive status having comorbidities, with the help of medical records department, done during 1st April 2020 to 31st March 2021. RESULTS : Out of 150 patients who had a renal abnormality, 40 (27%)had AKI, 110 ( 73%) had CKD, and of these patients, 96( 64%) patients underwent dialysis, 54( 36%) patients did not undergo dialysis, having high mortality mainly in patients having CKD than AKI. Compared to patients with comorbidity without renal abnormality and patients with renal abnormalities, the mortality was high in the later group of patients. CONCLUSION: There is a signicant effect of kidney disease on mortality in covid positive patients. Patients having CKD will have higher mortality compared with AKI. Even though the mortality was seen in patients having comorbidities without renal involvement, mortality was much higher in patients with renal involvement.