HISTOPATHOLOGICAL SPECTRUM OF OVARIAN TUMOURS IN REPRODUCTIVE AGE GROUP WOMEN OBSERVED AT A TERTIARY CARE HOSPITAL

2021 ◽  
pp. 73-76
Author(s):  
Sivakumar Vulava ◽  
P.R.D. Ganesh Basina ◽  
Aluri Anjanapriyanka ◽  
Uram. Arunajyothi

Aim and objectives: Ovarian tumours present with a wide variation in clinical presentation and morphological features. Ovaries apart from being a common sites of primary tumors, they are frequent sites for metastasis from organs like stomach, colon and breast. The present work has been undertaken to study the common morphologic and histological types of ovarian tumours in reproductive age group women. Materials and methods: A prospective study s study is conducted for a period of 3 years (August 2010 to September 2013). 100 cases of ovarian tumors in reproductive age women were selected for the present study. Age between 15 and 49 was taken as reproductive age. 100 cases of ovarian tumours in reproductive age women were selected for the present study. Age between 15 and 49 was taken as reproductive age. Out of the 100 cases 99 Results: were primary ovarian tumours, 1 was secondary / metastatic tumour. Out if the 99 primary tumours 94 were benign, 1 was borderline tumour and 4 were malignant tumours. Most tumours occurred in age between 30-40 years. Of the 99 primary tumours 85(90.4%) were surface epithelial tumours, 10 (10.6%) were germ cell tumours and 4 (4.2%) were sex-cord stromal tumours. 1 metastatic tumour, were noted. Benign ovarian tumours are more common than malignant tumours. Conclusion: Surface epithelial tumours are the most common type of all ovarian tumours. Surface epithelial tumours are the most common benign and malignant tumours in reproductive age group. The incidence, clinical presentation of the different types of ovarian tumours is extremely variable. Histopathology is still the gold standard in diagnosing most of ovarian tumours. Studying the macroscopic and microscopic features of different ovarian tumours will enable proper categorization into denite morphologic type.

Author(s):  
Michelle N. Fonseca ◽  
Madhavi J.

Background: Ovarian tumours can be seen at all stages of life but they differ in type, being mostly germ cell tumours in childhood, functional cysts in the reproductive age group (up to 45 years) and becoming increasingly malignant towards and after menopause. It also accounts for most prevalent cause of hospital admissions.Methods: This is a retrospective study conducted in the Department of Obstetrics and Gynaecology at a tertiary care hospital in Mumbai from August 2017 to August 2018. All patients with ovarian masses who were surgically managed were included in the study. The data of 30 patients was collected in excel sheet and analyzed by descriptive statistics.Results: Out of the 30 ovarian masses, 50 % were functional cysts, 46.6% were benign ovarian masses and 3.3% were borderline malignant. 46% of tumours were seen in the age group 21-30 years. More than 50 % tumours were seen in parous women. Most common presenting clinical symptom was pain in abdomen irrespective of the type of tumour. Most common complication was haemorrhage in the cyst. Laparoscopy was done in 4 patients and 26 required exploratory laparotomy. Most common surgery performed was unilateral cystectomy for functional ovarian cysts and benign ovarian tumours. Mucinous cystadenoma was the most common benign ovarian tumour, followed by dermoid cyst.Conclusions: Pre-operative diagnostic approach to a patient with ovarian mass includes careful history taking, thorough clinical examination, ultrasound and tumour marker assays in selected cases. Conservative surgery should be the goal to preserve fertility in young patients with ovarian tumours.


Author(s):  
Madhusmita Choudhury ◽  
Monoj K. Deka ◽  
Shah A. Sheikh

Background: Ovarian malignancy is the second most common cancer of the female reproductive system and the leading cause of death from gynecologic malignancy. With increase in longevity, the incidence of epithelial ovarian cancer is increasing and its etiopathology remains unknown. A female’s risk at birth of having ovarian tumour sometime in her life is 6-7%. Two third of ovarian tumours occur in women of reproductive age group. The aim was to study the distribution of morphological pattern of benign, malignant, and nonneoplastic lesions of the ovary in different age groups and to determine the likelihood of bilateral involvement in different morphologic subtypes.Methods: A retrospective study from January 2018 to December 2020 was undertaken. A total of 210 surgical specimens were obtained. Detailed clinical information and radiological findings were recorded from the case sheets. Grossing of the surgical specimens was done in the pathology department, followed by histological examination.Results: Of 210 cases, benign cases were 140 (66.7%), malignant cases were 70 (33.3%). Surface epithelial tumors were most common (116/55.2%) followed by germ cell tumors (76, 36.1%) followed by others. Serous cystadenoma was commonest benign tumor (58, 41.4%). Serous adenocarinoma was commonest malignant tumor (19, 27.1%). Benign tumours were more common in the younger age group i.e. <40 years of age whereas malignant tumours were supervenes with increase in age. Most benign ovarian tumors (54, 38.6%) were seen between 31-40 years whereas most malignant tumors (24, 34.3%) were seen above 40 years. In 1st two decades, germ cell tumors were more common than other tumours.Conclusions: The prognosis and varying therapeutic strategies of ovarian tumours necessitate an accurate pathological evaluation. Histopathological study is still the gold standard in diagnosing most of these tumours. 


Author(s):  
Akinfenwa T. Atanda ◽  
Osondu C. Agu ◽  
Abubakar K. Modu K. Modu

Mullerian adenosarcomas are rare tumours that may be found in any part of the female genital tract including cervix. They are more common in the reproductive age group and rare among blacks. When they present in the cervix they may be clinically misdiagnosed as an endocervical polyp and histologically as an adenofibroma. Clinical presentation is mostly as irregular vagina bleeding and as a mass in the vagina. Meticulous histopathological evaluation is crucial for its optimum management.


2021 ◽  
Vol 11 (1) ◽  
pp. 63-71
Author(s):  
Pallerla Srikanth ◽  
Mysore Narasimha Vranda ◽  
Priya Treesa Thomas ◽  
Kenchaiah Raghvendra

Background and Purpose: The purpose of this study was to understand the relationship between quality of life and stigma among reproductive age group women with epilepsy.Methods: A cross-sectional descriptive study was conducted to assess the data from the 49 women with epilepsy from a tertiary care hospital in India. Quality of life was evaluated with the quality of life in epilepsy-31 questionnaire and stigma was evaluated with the stigma scale of epilepsy. Data also included socio-demographic and clinical characteristics.Results: The mean age of the participants was 24.67±3.72 years. Quality of life total score (r=-0.485**) and seizure worry domain (r=-0.427**) were significantly negatively correlated with stigma total score at p<0.01 level. Being uneducated, married, unemployed, having children, having generalized tonic-clonic seizures, duration of illness (˃10 years), and consuming levetiracetam, anti-epileptic drug (AED), were the significant contributing factors for low quality of life among women with epilepsy during the reproductive age group. Belonging to lower socio-economic status and taking more than two AEDs were also associated with lower quality of life among women with epilepsy, which are trending towards significance.Conclusions: The study assessed the relationship between the quality of life and the Stigma scale of epilepsy and demonstrated the impact of stigma and quality of life on socio-demographic and clinical variables of women with epilepsy under the reproductive age group. To enhance the quality of life and reduce the stigma levels among women with epilepsy, some of the modifiable parameters can be considered by the multidisciplinary health care professionals from the findings of the current research.


2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Eti Rajwar ◽  
Shradha S. Parsekar ◽  
Bhumika Tumkur Venkatesh ◽  
Zinnia Sharma

Abstract Background Micronutrient deficiency affects the health and development of vulnerable population such as children and pregnant women. Measures such as fortification of food and supplementation have been implemented to prevent or control deficiencies related to micronutrients. Objective To assess the effect of vitamin A, vitamin D, and calcium fortification and supplementation on nutritional status of women in reproductive age group. To assess the toxicities and adverse events related to intervention. Methodology Systematic reviews including RCTs on women of reproductive age group provided with vitamin A, vitamin D, and calcium supplementation or fortified food were included, to report all malnutrition-related outcomes due to deficiency of the abovementioned micronutrients. The Cochrane Database of Systematic Reviews, EPPI Centre, Campbell Collaboration, PubMed, Web of Science, and Scopus were searched electronically for English language publications, until 31 March 2018. Hand searching of the articles was done from the Journal of Food Science and Technology. Two independent reviewers selected the systematic reviews, extracted data, and assessed for the quality. Results A total of 16 systematic reviews were included in narrative synthesis. Supplementation of vitamin A was reported to result in increased maternal serum retinol concentrations and increased breast milk retinol concentration. It reduced the risk of anemia (Hb < 11 g/dL) and reduced maternal clinical infection. Vitamin D supplementation increased 25-hydroxy vitamin D levels. There was insufficient evidence for the effect on bone mineral density and serum calcium levels. Calcium supplementation did not have any significant effect on body weight, weight gain, and body mass index of the participants. Conclusion This overview of systematic reviews reiterates the nutritional importance of vitamin A, vitamin D, and calcium supplementation for the reproductive age women. However, there was no empirical evidence available for fortification of food with vitamin A, vitamin D, and calcium and nutritional benefits of the same for reproductive age women, therefore thrusting upon the need of conducting future quality research, i.e., clinical trials and systematic reviews for food fortification. Systematic review registration A priori protocol for this overview of systematic reviews was registered in PROSPERO with registration number CRD42018089403.


Sign in / Sign up

Export Citation Format

Share Document