COMPARATIVE ASSESSMENT OF MICROALBUMINURIAAND EARLY UTERINE ARTERY DOPPLER INDICES AS A PREDICTOR OF DEVELOPING PREECLAMPSIA.

2021 ◽  
pp. 21-24
Author(s):  
Monojit Chakrabarti ◽  
Chandreyee Dey ◽  
Sayani Mandal
Keyword(s):  
Uterine Artery ◽  
Late Pregnancy ◽  
Screening Tools ◽  
Chi Square ◽  
Prospective Longitudinal Study ◽  
Uterine Artery Doppler ◽  
Antenatal Period ◽  
Chi Square Test ◽  
Doppler Indices ◽  
Prospective Longitudinal

BACKGROUND : As we know hypertensive disorders in pregnancy is always a deadly threat to mothers and fetus. Mothers will be in large benet if we predict it earlier. Easy reproducible non cumbersome screening test are needed for it. METHODS: This is a Prospective longitudinal study. Patients were studied from rst trimester to late trimester in the department of g & o for 1 year who fullled the inclusion and exclusion criteria. They were observed through out the time period. All the data were studied by chi – square test . Ap value of <.05 was considered statistically signicant. RESULTS : Out of 150 antenatal mothers 12 developed pre-eclampsia (including 1 eclampsia) among which 8 had microalbuminuria during their antenatal period. 10 mothers had microalbuminuria but did not develop pre-eclampsia, 4 of them developed pre-eclampsia but they did not have microalbuminuria during antenatal period. 128 mothers did not have microalbuminuria and they did not develop pre-eclampsia When RI of >0.58 was used as cut off value at 18weeks of POG. In our study of 150 antenatal mothers 12 developed pre-eclampsia (including 1 eclampsia) among which 4 had RI of > 0.58 during their antenatal period. 6 of them had RI of >0.58 but did not develop pre-eclampsia, 8 of them developed pre-eclampsia but did not have increased RI value. 132 mothers did not have raised RI value and they did not develop pre-eclampsia. CONCLUSION Both the screening tools are easy to done. Microalbuminuria and early uterine artery doppler indices can be used as predictor of detecting preeclampsia. Mothers with no microalbuminuria and uterine artery RI value of < 0.58 would have less chance of developing pre eclampsia in late pregnancy.

scholarly journals Uterine Artery Doppler Ultrasonography for First Trimester Prediction of Preeclampsia in Individuals at Risk from Low-Resource Settings

Medicina ◽  
2020 ◽  
Vol 56 (9) ◽  
pp. 428
Author(s):  
Mihaela Oancea ◽  
Mihaela Grigore ◽  
Razvan Ciortea ◽  
Doru Diculescu ◽  
Diana Bodean ◽  
...  
Keyword(s):  
At Risk ◽  
Pregnant Women ◽  
Uterine Artery ◽  
Doppler Ultrasonography ◽  
First Trimester ◽  
Prospective Longitudinal Study ◽  
Uterine Artery Doppler ◽  
Doppler Examination ◽  
Non Invasive ◽  
Prospective Longitudinal

Background and objectives: The objective of this study was to evaluate the potential of first trimester uterine artery Doppler ultrasonography for the early prediction of preeclampsia (PE), in at-risk pregnant women. Materials and Methods: This was a prospective longitudinal study, including 120 Caucasian pregnant women with risk factors for PE. The potential of pulsatility indexes (PI) and notch was assessed as a tool for preeclampsia screening. Results: Doppler examination of the uterine artery performed early at 11–14 WA allows the detection of pregnancies that will develop PE with a sensitivity of 61.5% and a specificity of 63.8% based on PI analysis. Predictive power increases slightly by adding bilateral notch (sensitivity = 65.4%; specificity = 66%). Conclusions: Uterine artery Doppler examination is an effective non-invasive screening test for the development of PE in pregnancies at risk, particularly appropriate in health systems with limited means of evaluating other biomarkers.

scholarly journals Association between reduced fetal movements at term and abnormal uterine artery Doppler indices

2014 ◽  
Vol 43 (5) ◽  
pp. 548-552 ◽  
Author(s):  
G. Pagani ◽  
F. D'Antonio ◽  
A. Khalil ◽  
R. Akolekar ◽  
A. Papageorghiou ◽  
...  
Keyword(s):  
Uterine Artery ◽  
Uterine Artery Doppler ◽  
Reduced Fetal Movements ◽  
Fetal Movements ◽  
Doppler Indices

scholarly journals Pediatric Brain tumors in Southeast Nigeria; An 8-year prospective longitudinal cohort study

2019 ◽  
Author(s):  
Enoch Uche ◽  
Nkechi Judith Uche ◽  
Obinna V Ajuzieogu ◽  
Dubem Amuta ◽  
ephraim Onyia ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Survival Rates ◽  
Pediatric Brain Tumors ◽  
Common Symptom ◽  
Chi Square ◽  
Study Results ◽  
Chi Square Test ◽  
Poor Outcomes ◽  
Prospective Longitudinal ◽  
Pediatric Brain

Abstract Background: Pediatric brain tumors (PBT’s) from previous studies are associated with poor outcomes in our subregion. Methods. An 8 -year single center prospective study. All cases investigated with neuroimaging and treated were enrolled. Data was analyzed with SPSS (Inc) Chicago IL, USA version 23. Chi Square test, One-way Anova and confidence limits were used to evaluate associations using the 95% level of significance. Patients were followed up for a range of 1 to 7.5 years with a mean of 4.9 ±1.3years. Ethical approval was obtained for our study. Results: 95 patients were enrolled, 84 satisfied the study criteria. There were 45 males and 39 females, M: F=1.1. The mean age was 9.9±2.7 years 95%CI with a range of 9 months to 16 years. The most common symptom was headache for supratentorial lesions (73%) and gait disturbance (80.2%) for infratentorial lesions. More tumors were supratentorial in location (45(54.2%), while 33(37.1%) were infratentorial. Craniopharyngiomas (n=19), medulloblastomas(n=17) and astrocytomas (n=11) were the most common tumors. Hemoglobin genotype(AA and AS) had some influence on tumor phenotype, Odds ratio 8.9 and 3.3 for medulloblastoma and craniopharyngioma. 69 cases were microsurgically resected while 14 patients were treated with radiotherapy alone. The 30-day mortality for operated cases is 7.9±1.3%. Overall 1-year and 5-year survival was 67.9% and 53.6 % respectively. Survival rates varied among treatment groups (X2=8.9, P=0.017). Conclusion: Survival profile in this series suggests some improvement in comparison to previous studies from our region.

scholarly journals UTERINE ARTERY DOPPLER INDICES AS PREDICTIVE MEASURES FOR THE PRE-ECLAMPSIA AND INTRAUTERINE GROWTH RESTRICTION

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
MN Rashid ◽  
M Kari ◽  
R Rashid ◽  
MA Rana ◽  
A Amjad ◽  
...  
Keyword(s):  
Intrauterine Growth Restriction ◽  
Uterine Artery ◽  
Growth Restriction ◽  
Cross Sectional Survey ◽  
Maternal Complications ◽  
Cross Sectional ◽  
Uterine Artery Doppler ◽  
Intrauterine Growth ◽  
Pregnant Females ◽  
Doppler Indices

Preeclampsia and Intrauterine growth restriction (IUGR) remains as the important causes for the neonatal and maternal complications leading to even death in some cases. Uterine artery Doppler USG can be done transvaginally or trans abdominal and performed in the 1st or 2nd trimester of the pregnancy to detect these complications Doppler waveform suggested the high vascular resistance to blood flow. In our present study, we conclude uterine artery Doppler indices as prognostic procedure for the preeclampsia and intrauterine growth restriction. A cross-sectional survey design with convenient sampling technique was used. Mixture of standardized and self-modified structured questionnaire was undertaken to determine the indices of pre eclampsia and IUGR by uterine artery. The data was collected from Bahria International Hospital, Lahore during the period of 9 months. This study was included 162 pregnant females with identification of the main uterine artery on a longitudinal scan lateral to the uterus.  Initial diastolic notch of right and left side of the uterine artery waveforms was recorded. At every antenatal checkup, urine was tested for protein and blood pressure readings were taken to identify preeclampsia. Further analysis was done dividing patients as normotensive and those patients developing hypertension after 30 weeks of gestation. After delivery neonates observed for IUGR by head circumference and body weight. The study was concluded that from the total sample size of 162 pregnant females who undergoes uterine artery Doppler, 34% females shows diastolic notch and almost all of these later diagnosed with preeclampsia and 19.8% deliver babies with IUGR. So, based on the study, we have concluded that uterine artery Doppler is helpful to provide diagnosis of preeclampsia and IUGR in early pregnancy.

Pediatric Brain tumors in Southeast Nigeria; A prospective longitudinal cohort study

2019 ◽  
Author(s):  
Enoch Uche ◽  
Nkechi Judith Uche ◽  
Obinna V Ajuzieogu ◽  
Dubem Amuta ◽  
ephraim Onyia ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Pediatric Brain Tumors ◽  
Common Symptom ◽  
Chi Square ◽  
Study Results ◽  
Ethical Approval ◽  
Chi Square Test ◽  
Poor Outcomes ◽  
Prospective Longitudinal ◽  
Pediatric Brain

Abstract Background: Pediatric brain tumors (PBT’s) from previous studies are associated with poor outcomes in our sub region. Methods. An 8 -year single center prospective study. All cases investigated with neuroimaging and treated were enrolled. Data was analyzed with SPSS (Inc.) Chicago IL, USA version 23. Chi Square test, One-way Anova and confidence limits were used to evaluate associations at the 95% level of significance. Ethical approval was obtained for our study. Results: 103 patients were enrolled, 92 satisfied the study criteria. There were 45 males and 39 females, M: F=0.8. The mean age was 9.5±2.1 years 95%CI with a range of 7 months to 16 years. The most common symptom was headache for supratentorial lesions (73%) and gait disturbance (80.2%) for infratentorial lesions. More tumors were supratentorial in location (51 (55.4%), while 35(38.1%) were infratentorial. Craniopharyngiomas (n=22), medulloblastomas (n=17) and astrocytomas (n=12) were the most common tumors. Hemoglobin genotype (AA and AS) had some influence on tumor phenotype FT, P=0.033. 76 cases were microsurgically resected while 16 patients were treated with radiotherapy alone. The 30-day mortality for operated cases is 7.2±0.7%. Overall 1-year and 5-year survival was 66.7% and 52.3 % respectively. Survival School performance varied among treatment subgroups Conclusion: Survival profile in this series suggests some improvement in comparison to previous studies from our region. Keywords: Pediatric brain tumors, microneurosurgery, radiotherapy, survival

The use of uterine artery doppler indices for prediction of pre-eclampsia in Port-Harcourt, Nigeria

2019 ◽  
Vol 26 (4) ◽  
pp. 223
Author(s):  
EmechetaGabriel Okwudire ◽  
OmololaMojisola Atalabi ◽  
UgonnaMicheal Ezenwugo
Keyword(s):  
Uterine Artery ◽  
Uterine Artery Doppler ◽  
Port Harcourt ◽  
Doppler Indices

scholarly journals Role of obstetric colour doppler studies in predicting perinatal outcome in pregnancy induced hypertension

2020 ◽  
Vol 9 (3) ◽  
pp. 1073
Author(s):  
Ritu Mishra ◽  
Aditya P. Misra
Keyword(s):  
Perinatal Outcome ◽  
Uterine Artery ◽  
Ductus Venosus ◽  
Pregnancy Induced Hypertension ◽  
Doppler Studies ◽  
Colour Doppler ◽  
Uterine Artery Doppler ◽  
Induced Hypertension ◽  
Improve Pregnancy Outcome ◽  
Doppler Indices

Background: Pregnancy induced hypertension (PIH) is associated with adverse perinatal outcome. Multi vessel colour Doppler studies are useful in these cases for timely intervention. The aim of present study was to know the significance of umbilical, middle cerebral and uterine artery Doppler in PIH and to analyse their role in predicting perinatal outcome.Methods: This is a study of 150 pregnant women with pregnancy induced hypertension (PIH). These patients were evaluated with colour Doppler and were followed subsequently for any adverse perinatal outcome.Results: Out of 150 cases 70% of cases were found in 20-30 years age group. 98 cases had abnormal uterine artery Doppler indices accounting for 65.3%, while 52 cases had a normal Doppler index accounting for 34.3%. Out of 150 cases, 94 (64.6%) cases had abnormal middle cerebral artery. In our study 53 cases had abnormal umbilical artery Doppler indices accounting for 35.4%, while 97 cases had a normal Doppler index accounting for 64.6%. Out of 150 cases in our study 27 cases had Reversal of a wave in ductus venosus waveform that is in 18%. In this study total 5 cases (35.7%) of perinatal mortality were seen.Conclusions: The knowledge of various doppler parameters may help to improve pregnancy outcome and identification of PIH at earliest gestation age as compared to other antepartum test modalities.

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