A STUDY ON SIGNIFICANCE OF COOMBS TEST AND ANTIBODY SCREENING IN PATIENTS WITH CHRONIC ANAEMIA IN A TERTIARY CARE HOSPITAL

2021 ◽  
pp. 53-54
Author(s):  
A. Mangaiyarkarasi ◽  
R. Synthia Selvakumari
Keyword(s):  
Blood Transfusion ◽  
Tertiary Care ◽  
Reference Laboratory ◽  
Care Hospital ◽  
Coombs Test ◽  
Chronic Anemia ◽  
Cell Antibody ◽  
Chronic Anaemia ◽  
Male Patients ◽  
Transfusion Protocol

Most of the inpatients admitted in our hospital for the evaluation of anemia needs blood transfusion as part of the treatment. A total of 719 cases from medical ward received blood transfusion from the period of January 2016 to December 2016. Irrespective of the provisional diagnosis of case, we performed Direct Coombs test, Indirect Coombs test, Autocontrol and 3 cell antibody panel from the samples received for cross matching. Of that 532 case were females, 187 cases were male patients. Our transfusion protocol included identication of presence of antibodies including the following antibodies: A, B, C, c, D, E, e, Lea, Leb, K, Fya, Fyb, Jka, Jkb, M, N, S, s, by using 3 cell panel. Screening for antibodies was performed before transfusion, according to standard antiglobulin techniques. If screening was positive, the antibody was identied by means of panels of reagent red cells, identication was conrmed by a regional reference laboratory. We identied most of the female patients between the age group 20 to 30 with chronic anemia were found to have DCTpositive hemolytic anemia. Few patients had only DCTpositive without abnormal antibodies and some had DCTnegative AIHA.

A RETROSPECTIVE STUDY OF BLOOD TRANSFUSION PRACTICES IN A TERTIARY CARE HOSPITAL OF NORTH INDIA.

2021 ◽  
pp. 25-29
Author(s):  
Rakesh Kumar Sharma ◽  
Shahid Anjum Awan ◽  
Vijay Sawhney
Keyword(s):  
Blood Transfusion ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Transfusion Practice ◽  
Blood Bank ◽  
Control Measures ◽  
North India ◽  
Care Hospital ◽  
Important Concern ◽  
Life Saving

INTRODUCTION: Blood transfusion is an important concern for the society, as it is life saving for patients with bleeding disorders, accidents, surgeries, inherited/acquired hematological diseases and malignancies. Generally, donors are classied into the following categories: voluntary, family replacement, remunerated or paid donors, and autologous donor. AIMS & OBJECTIVES:To understand the importance of Blood & its safe Transfusion practice in a Teaching Hospital. METHODOLOGY: An Observational study was conducted over a period of 12 months from January 2019 to December 2019 in a 750 –bedded Tertiary Care Hospital of Jammu(UT). OBSERVATIONS: In addition to providing Blood-Transfusion Services to the patients admitted in SMGS Hospital Jammu & Other Associated Hospitals of GMC Jammu, the Blood-Bank is also catering to the needs of Registered Private Nursing Homes & Hospitals of Jammu(UT).This Blood-Bank has exceptionally maintained a record of consuming the whole stock of Blood without wasting even a single pint of blood. DISCUSSION: The Aim of Blood Transfusion Services is to supply good Quality of Blood & its Components to the Patients & avoid any risk to the Donors as well as Recepients. Hence it is extremely essential to institute strict Quality Control Measures RECOMMENDATIONS: Recommended that Upgradation of Blood-Bank is essential to cater with the needs of Additional bed-strength that SMGS Hospital is going to acquire in the coming future.

scholarly journals Investigating the prolongation of blood transfusion frequency in thalassemic children by omega 3 fatty acid and protein supplementations through milk

2021 ◽  
Vol 8 (1) ◽  
pp. 17
Author(s):  
Amol Kumar ◽  
Preeti Doshi ◽  
Ramdas Dahiphale ◽  
Ansh Chaudhary ◽  
Bhupendra Chaudhary
Keyword(s):  
Fatty Acid ◽  
Blood Transfusion ◽  
Screening Program ◽  
Genetic Disorder ◽  
Tertiary Care ◽  
Hemoglobin Level ◽  
Blood Transfusions ◽  
Care Hospital ◽  
Omega 3 ◽  
Omega 3 Fatty Acid

<p class="abstract"><strong>Background:</strong> Thalassemia is an inherited genetic hemoglobin disorder wherein, afflicted child is born when both parents are carriers for defective alpha or beta hemoglobin gene. The thalassemias are the most common genetic disorder on a worldwide basis. The requirement of frequent blood transfusions in these patients pose a substantial burden on the health care system.</p><p class="abstract"><strong>Methods:</strong> A prospective observational study was conducted across 6 months (July 2018-December 2018) in a tertiary care hospital, Pune. The present study included 30 registered patient &amp; their past 6 months record of blood transfusion (esp frequency), previous hemoglobin levels, height &amp; weight. All these parameters were compared 6 months after supplementation with Omega 3 fatty Acids &amp; proteins.</p><p class="abstract"><strong>Results:</strong> Total 16 of 28 patient showed that the average durations between two blood transfusions was increased by minimum 01 day to a maximum of 5 days. The average number of blood bag required was less than required blood bags in the period of pre supplementation. 20 of 28 patients showed a rise in hemoglobin level from a range of 0.5 to 1.2 gm/dl.  </p><p class="abstract"><strong>Conclusions: </strong>In a country like India, with the high frequency of hemoglobinopathies, causing increased burden on the society, it is necessary to control the incidence by effective steps. Low cost and easily administered supplementation by omega 3 fatty acid and proteins may reduce the requirement of repeated blood transfusion along with increase in hemoglobin level. Implementation of carrier screening program offering genetic counseling and prenatal diagnosis followed by selective termination of affected cases would help in preventing the disease.</p>

scholarly journals Clinico-Demographic Profile and Pregnancy Outcome in Placenta Previa: A Study from Tertiary Care Hospital

2017 ◽  
Vol 15 (1) ◽  
pp. 2-4
Author(s):  
Husneyara Haque ◽  
Upendra Pandit
Keyword(s):  
Birth Weight ◽  
Blood Transfusion ◽  
Low Birth Weight ◽  
Pregnancy Outcome ◽  
Tertiary Care Hospital ◽  
Placenta Previa ◽  
Tertiary Care ◽  
College Teaching ◽  
Morbidity And Mortality ◽  
Care Hospital

Introduction: Placenta previa is an obstetric complication which causes considerable maternal and fetal morbidity and mortality during pregnancy. This study is done with the objective to find out the clinico-demographic factors associated with placenta previa and to analyze maternal and perinatal outcome in these cases. Methods: This was a retrospective study done in the department of Obstetrics and Gynecology of Nepalgunj Medical College Teaching Hospital, Nepalgunj, a tertiary care hospital from Midwestern Nepal. Relevant data were retrieved from maternity register from June 2015 to May 2017. All women who had undergone caesarean section for placenta previa were included in this study. Result: Out of total 5812 deliveries during the study period there were 50 caesarian sections done for placenta previa which is 0.86% of total deliveries. Maximum number of mothers belonged to 26- 30 years of age group. Commonest type of placenta previa was minor type. About 72% were multiparous. 20% had previous LSCS and 24% had previous abortion. Postpartum hemorrhage was present in 36% mothers and 32% received blood transfusion. About 64% new born were preterm and low birth weight. 34% babies had less than 7 apgar score at 5 min. Still births were 6%. Conclusion: Placenta previa poses greater risk and need of blood transfusion to mother as well as birth of preterm and low birth weight babies which leads to perinatal morbidity and mortality. Timely diagnosis, regular antenatal check up and effective management may improve pregnancy outcome.

Acute blood transfusion reactions in a tertiary care hospital in Pakistan ‐ an initiative towards haemovigilance

2018 ◽  
Vol 29 (4) ◽  
pp. 275-278
Author(s):  
M. Borhany ◽  
N. Anwar ◽  
H. Tariq ◽  
N. Fatima ◽  
A. Arshad ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Transfusion Reactions

Increasing Seroprevalence of Hepatitis C Virus among Blood Donors - A 3 Year Study in North India

2021 ◽  
Vol 8 (07) ◽  
pp. 379-383
Author(s):  
Jagjeewan Ram ◽  
Namrata Nigam ◽  
Aparna Singh ◽  
Lubna Khan
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Blood Transfusion ◽  
Blood Donors ◽  
Tertiary Care ◽  
North India ◽  
Enzyme Linked Immunosorbent Assay ◽  
Care Hospital ◽  
Hepatitis C Infection ◽  
Case Volume

BACKGROUND The primary aspect of blood transfusion lies in the availability of blood and blood components which are tested and reported negative for transfusion transmitted infections (TTI’s). The increased seroprevalence of TTI’s indicate their prevalence in general public. The study was conducted to analyse the increasing seroprevalence of hepatitis C virus (HCV) over a period of 3 years. The objectives of the study determine the seroprevalence of hepatitis B (HBV), hepatitis C (HCV) and human immunodeficiency virus (HIV) among the voluntary blood donors at a tertiary care hospital & associated blood bank. METHODS This cross-sectional study was done at the Department of Transfusion Medicine, GSVM Medical College, Kanpur, Uttar Pradesh, over a period of 3 years from July 2017 to June 2020. The samples collected were screened by enzyme-linked immunosorbent assay (ELISA) tests. RESULTS A total of 69561 blood units were collected during this 3-year study from July 2017 to June 2020. Of all the blood bags screened, the highest prevalence was seen for HBV followed by HCV and HIV. 949 (1.4 %) were reactive for HBV, 75 (0.1 %) were reactive for HIV and 332 (0.5 %) were reactive for HCV. The results show a remarkable increase in the seropositivity for hepatitis C infection. CONCLUSIONS The seroprevalence of HCV has seen an increase in case load over the years as compared to HBV and HIV. This increase in case volume is indicative of impending liver diseases progressing to chronic stage over the years. Thus, it is imperative to create awareness in the general population to help reduce the risk factors responsible for HCV infection. KEYWORDS Blood Transfusion, Voluntary Donors, HCV, HBV, HIV, Seroprevalence, Transfusion Transmitted Infections (TTI’s)

Clinical and economic impact of oxidized regenerated cellulose for surgeries in a Chinese tertiary care hospital

2020 ◽  
Vol 9 (15) ◽  
pp. 1079-1090
Author(s):  
Zhaoxin Qian ◽  
Fang Xiong ◽  
Xiaozhe Xia ◽  
Pengjuan Gu ◽  
Qinghong Wang ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Tertiary Care ◽  
Hospital Costs ◽  
Regenerated Cellulose ◽  
Care Hospital ◽  
Oxidized Regenerated Cellulose ◽  
Transfusion Volume ◽  
Manual Pressure ◽  
The Impact ◽  
Arthroplasty Surgery

Aim: To assess the impact of oxidized regenerated cellulose (ORC) on blood transfusion and hospital costs associated with surgeries. Patients & methods: This retrospective cohort study selected ten surgeries to create propensity-score matching groups to compare ORC versus nonORC (conventional hemostatic techniques such as manual pressure, ligature and electrocautery). Results: NonORC was associated with both higher blood transfusion volume and higher hospital costs than ORC in endoscopic transnasal sphenoidal surgery, nonskull base craniotomy, hepatectomy, cholangiotomy, gastrectomy and lumbar surgery. However, nonORC was associated with better outcomes than ORC in open colorectal surgery, mammectomy and hip arthroplasty surgery. Conclusion: When compared with conventional hemostatic technique, using ORC could impact blood transfusion and hospital costs differently by surgical settings.

Rise of Haemoglobin after Blood Transfusion in Children Without Active Bleeding

2020 ◽  
Vol 40 (2) ◽  
pp. 125-129
Author(s):  
Rupesh Shrestha ◽  
Srijana Basnet ◽  
Fakir Chandra Gami
Keyword(s):  
Blood Transfusion ◽  
Blood Product ◽  
Tertiary Care ◽  
Haemoglobin Concentration ◽  
Severe Anaemia ◽  
Active Bleeding ◽  
Care Hospital ◽  
Red Cell ◽  
Donor Blood ◽  
Before And After

Introduction: Blood transfusion is a common practice among children with severe anaemia. A common assumption among physician is that transfusion of 5 ml/kg packed red cell will increase the haemoglobin of the recipient by 1 gm/dl. This study was aimed at assessing the effect of volume of blood product and hematocrit of donor blood in the rise of haemoglobin concentration after transfusion in children without active bleeding. Methods: A prospective observational study was conducted in 32 children aged between one to 15 years without active bleeding who received blood transfusion in Paediatric ward and Paediatric Intensive Care Unit of a tertiary care hospital in Nepal from December 2013 to November 2014. Haemoglobin levels before and after transfusion were compared and any adverse reactions that occurred during transfusion were recorded. Hematocrit of each donor blood was measured. Results: The overall rise of haemoglobin after transfusion of blood product with hematocrit of 53 ± 8.9 % at the rate 14.5 ± 6.0 ml/kg was 2.7 ± 1.4 gm/dl. The rise of haemoglobin after transfusion of whole blood with hematocrit of 38.8 ± 4.4% at the rate 15.5 ± 6.9 ml/kg was 1.8 ± 1.2 gm/dl. The rise of haemoglobin after transfusion of packed cell with hematocrit 57.0 ± 4.8 % at the rate 14.2 ± 5.8 ml/kg was 2.9 ± 1.4 gm/dl. Conclusion: This study supports the general consensus of 1 gm/dl rise of haemoglobin after transfusion of packed red cell at 5 ml/kg.  

Blood Transfusion for Primary Postpartum Hemorrhage: A Tertiary Care Hospital Review

2008 ◽  
Vol 30 (11) ◽  
pp. 1002-1007 ◽  
Author(s):  
Mrinalini Balki ◽  
Sudhir Dhumne ◽  
Shilpa Kasodekar ◽  
Jose C.A. Carvalho ◽  
Gareth Seaward
Keyword(s):  
Blood Transfusion ◽  
Postpartum Hemorrhage ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital
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