Characteristic Suspect Related Incidence Of Dengue Hemorrhagic Fever (DHF): Cross Sectional Study On Suspect In Endemic Area Semarang City, Indonesia

2019 ◽  
Vol 22 (11) ◽  
pp. 420-426
Author(s):  
Martini Martini ◽  
Retno Hestiningsih ◽  
Gana Maulida ◽  
Atik Mawarni ◽  
Indranilla Kustamrini Samsuria
2009 ◽  
Vol 49 (5) ◽  
pp. 259
Author(s):  
Hendra Widjaja ◽  
Max F. J. Mantik

Background Thrombocyte and endothelial cells play animportant role in dengue hemorrhagic fever pathogenesis.Thrombomodulin is a part of glycoprotein membrane inendothelial cells. Therefore, thrombomodulin level willincrease if endothelial cells disruption occurs.Objective To acknowledge the correlation between thedegree of dengue hemorrhagic fever and thrombomodulinlevel.Methods This was a cross-sectional study. Subjects werehospitalized pediatric patients with age ranging from oneto 13 year old in pediatric ward at Pro£ Dr. R.D. KandouHospital, Manado, who had fever. Three milliliters of bloodwere taken from vein, and were divided for two tests whichwere routine blood analysis and thrombomodulin analysis.Different data resulted from the dengue hemorrhagic fevergroup were processed, and analyzed statistically using F Testand LSD (least significant difference) test. The relationbetween dengue hemorrhagic fever and thrombomodulinwas analyzed with Spearman correlation coefficient.Results There was a significant result in the difference ofthrombomodulin level on four dengue hemorrhagic fevergroups which were classified according to the severity ofdengue hemorrhagic fever. There was a very significantpositive correlation between the severity of denguehemorrhagic fever and thrombomodulin level in detectingendothelial cells impairment.Conclusion Thrombomodulin level can be used as amarker to detect endothelial cells impairment in denguehemorrhagic fever. Higher grade of dengue hemorrhagicfever will have higher thrombomodulin level.


2015 ◽  
Vol 21 (2) ◽  
pp. 136-141 ◽  
Author(s):  
Pattara Rattanawong ◽  
Wasawat Vutthikraivit ◽  
Attawit Charoensri ◽  
Tanawat Jongraksak ◽  
Awapa Prombandankul ◽  
...  

2021 ◽  
Vol 13 (1) ◽  
pp. 27-34
Author(s):  
Retno Hestiningsih ◽  
Govinda Restu Syahputra ◽  
Martini Martini ◽  
Sri Yuliawati ◽  
M. Arie Wuryanto ◽  
...  

Sendangmulyo Village is one of the DHF (Dengue Hemorrhagic Fever) endemic areas in Semarang City. Previous studies reported that Aedes spp. active biting at night (nocturnal biting activity) in some areas in Indonesia. This indicates that changes in the blood-sucking behavior of Aedes spp mosquitoes can have an impact on dengue transmission. This research is a descriptive study with a cross-sectional study design. The study was conducted in 64 houses. The mosquito field collection was carried out using the resting mosquito collection method at 18.00-06.00 WIB. Observations of environmental parameters were also carried out to determine the temperature and humidity of the environment around the breeding grounds of Aedes spp. The results showed that there was a change in Aedes spp's blood-sucking activity from 16.00-17.00 WIB to 18.00-20.00 WIB. The distribution of Aedes albopictus in Sendangmulyo Village was 18% of the total Aedes spp. mosquitoes collected with a Resting Rate (RR) value of 0.98%. The average temperature and humidity in the area were 28.6 °C and 77.2%, respectively. This change in blood-sucking activity in Aedes spp has the potential to increase the risk of spreading DHF in Sendangmulyo Village. Dengue Hemorrhagic Fever vector control efforts need to be improved. Abstrak Kelurahan Sendangmulyo merupakan salah satu daerah endemis DBD (Demam Berdarah Dengue) di Kota Semarang. Studi-studi sebelumnya melaporkan bahwa Aedes spp. aktif menggigit pada malam hari (aktivitas menggigit nokturnal) di beberapa daerah di Indonesia. Hal ini mengindikasikan adanya perubahan perilaku menghisap darah nyamuk Aedes spp. dapat berdampak pada penularan dengue. Penelitian ini merupakan penelitian deskriptif dengan desain studi cross sectional. Penelitian dilakukan pada 64 rumah. Koleksi lapangan nyamuk dilakukan dengan metode  koleksi nyamuk istirahat  pada pukul 18.00-06.00 WIB. Pengamatan parameter lingkungan juga dilakukan untuk mengetahui suhu dan kelembaban lingkungan disekitar tempat perkembangbiakan Aedes spp. Hasil penelitian menunjukkan adanya perubahan aktivitas menghisap darah Aedes spp dari pukul 16.00-17.00 WIB menjadi pukul 18.00-20.00 WIB. Sebaran Aedes albopictus di Kelurahan Sendangmulyo adalah  18% dari total nyamuk Aedes spp yang terkoleksi dengan nilai Resting Rate (RR) sebesar 0,98%. Rata-rata suhu dan kelembaban di daerah tersebut masing-masing adalah 28,6 °C dan 77,2%. Perubahan aktivitas menghisap darah pada Aedes spp ini berpotensi meningkatkan risiko penyebaran DBD  di  Kelurahan Sendangmulyo. Upaya pengendalian vektor DBD perlu ditingkatkan.  


2021 ◽  
Vol 886 (1) ◽  
pp. 012065
Author(s):  
S Nurjanah ◽  
T Atmowidi ◽  
U K Hadi ◽  
D D Solihin ◽  
W Priawandiputra

Abstract Aedes sp. are vectors of the dengue virus that causes Dengue Haemorrhagic Fever (DHF). The purposed of this study to analyze habitat characteristics of Aedes sp. based on the entomological index and measure the density and species of larvae Aedes sp. The research was analytic observational with a cross-sectional study was conducted 3 subdistricts of endemic in Bandar Lampung. The results showed that from 3 locations, namely Sukarame, Kemiling and Tanjung Seneng, the House Index (HI) values were 41, 38, 31, respectively. The Container Index (CI) values were 14, 12, 10 respectively and the Breteau index (BI) values were 105, 77, 60 respectively. The result of density figure (DF) were 5-6 which means the density of Aedes sp. were moderate to high. The result of identification of larvae were 3 species of mosquito were Aedes aegypti, Aedes albopictus and Culex quinquefasciatus. The dominant spesies of larvae were found are Ae. aegypti. The characteristics of larvae habitat as a risk factor for increasing the density of mosquito in Bandar Lampung are buckets or container made of plastic or cement and dispenser, light colour, direct light exposure, 1-20 liters water volume, no cover container, no drainage, and no fish rearing.


Author(s):  
Azza A Abbas ◽  
Hiba A A Ali ◽  
Mohamed A Alagib ◽  
Huda F S Salih ◽  
Isam M Elkhidir ◽  
...  

Abstract Background Hantaviruses are enveloped negative sense RNA viruses that cause hemorrhagic fever with renal syndrome. This study aimed to identify the prevalence of Hantavirus IgG antibodies and possible risk factors for Hantaviruses infections among end-stage renal disease (ESRD) patients attending the Dr Salma dialysis center in Sudan. Methodology This was a cross-sectional study in which 91 ESRD patients and 30 healthy plasma samples were screened for Hantavirus IgG antibodies using ELISA. A questionnaire containing sociodemographics, history of rat exposure and clinical data information was filled in by each ESRD patient. Results In this study, 9 out of 91 ESRD patients (9.9%) tested positive for Hantaviruses antibodies (IgG) while none of the 30 healthy plasma samples showed seropositivity. There was no statistically significant association between age, gender, educational level and rat exposure and Hantavirus infection in ESRD patients (p>0.05) Conclusion This study is the first to be conducted in Sudan regarding Hantaviruses and ESRD. The prevalence of Hantavirus antibodies among ESRD patients is high compared with findings reported in the literature from studies conducted on the same group of patients. It points to an interesting question as to whether Hantaviruses have an association with ESRD but further studies are needed before drawing any conclusions.


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