scholarly journals Results of the use of natural healing factors of Crimea in the treatment of patients with chronic generalized periodontitis with the background of gastroenterological pathology

2021 ◽  
Vol 19 (1) ◽  
pp. 71-76
Author(s):  
S. G. Bezrukov ◽  
I. F. Feshchenko ◽  
E. I. Belenova ◽  
E. A. Tarasenko ◽  
V. V. Nikolenko
Keyword(s):  
Inflammatory Diseases ◽  
The State ◽  
Control Group ◽  
Complex Treatment ◽  
Chronic Inflammatory Diseases ◽  
Periodontal Tissues ◽  
Treatment And Prevention ◽  
Natural Healing ◽  
Positive Results

Relevance. Currently, researchers pay close attention to the study of chronic diseases that have a direct or indirect impact on the state of the patient’s dental status. It is known that chronic inflammatory diseases of the oral organs are, often simultaneously, permanent foci of infection that affect the state of other systems and organs. The general list of such diseases includes: chronic gingivitis, chronic generalized periodontitis, glossitis, gingivostomatitis.Aim. The aim of the study was to study the effectiveness of complex conservative therapy, including natural therapeutic factors of Crimea, in patients with chronic inflammatory diseases of the oral organs, occurring against the background of somatic pathology.Materials and methods. The objects of the study were periodontal tissues in 70 people with chronic generalized periodontitis (CGP) and gingivostomatitis, occurring against the background of gastrointestinal (GI) diseases.Results. The results obtained indicate that complex treatment with local application of hydrotherapy named “PhytoBiol” and thermal Saka mineral water (in a dilution of 1:4), combined with periodontal dressings according to the recipe proposed by us, cause persistent remission of these diseases, contribute to the improvement of periodontal tissues and oral mucosa. Thus, complex treatment of inflammatory diseases of periodontal tissues in patients in the main group (n = 35) led to long-term remission in 82.33% of cases, while in the control group the result was 69.5% (at p < 0.05).Conclusions. The positive results, which were obtained, give grounds to recommend the proposed complex of treatment and prevention of exacerbations of this chronic disease for use in practical health care.

The effect of hirudotherapy on cerebral circulatory homeostasis in patients with genital endometriosis

2020 ◽  
pp. 58-66
Author(s):  
Ya. I. Uraeva ◽  
I. I. Ivanova ◽  
N. N. Lazarenko ◽  
E. V. Filatova ◽  
I. A. Pankova ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Drug Therapy ◽  
Cerebral Circulation ◽  
The State ◽  
Control Group ◽  
Complex Treatment ◽  
Statistical Regression ◽  
Treatment Results ◽  
Standard Drug ◽  
Before And After

The results of the treatment of women (n = 94) suffering from genital endometriosis are presented. The first (control, n = 30) group of women received standard drug therapy; the second (main, n = 64) group of women additionally had hirudotherapy procedures using medical leeches. The course of treatment consisted of 10–12 procedures. The state of cerebral circulation was assessed according to the rheoencephalography data before and after the treatment, as well as after 1, 3, 6, and 9 months. As a result, in patients in the 2-nd (main) group receiving complex treatment, the state of cerebral circulation improved signifi cantly. Moreover, according to the statistical regression analysis, it was possible to predict its further decrease by two periods ahead, compared with the treatment results in patients in the 1-st (control) group.

Pathogenetic features of periodontitis as complications of orthodontic treatment

2021 ◽  
pp. 64-68
Author(s):  
A. К. Sheregov ◽  
М. S. Mustafayev ◽  
Z. F. Kharaeva
Keyword(s):  
Orthodontic Treatment ◽  
The State ◽  
Complex Treatment ◽  
Periodontal Tissues ◽  
Different Levels

The article presents the results of clinical and microbiological studies and immunological features of the state of periodontal tissues in patients with moderate periodontitis, which developed as a complication of orthodontic treatment. It was found that at the later stages of orthodontic treatment with the development of periodontitis, a complex of persistent changes in the periodontal tissues at different levels of pathogen-esis was revealed in patients. In this connection, in order to plan the complex treatment of patients with periodontitis, which has developed as a complication of orthodontic treatment, and to predict the course of the disease, it is necessary to influence the established and mutually supportive links and indicators of pathogenesis.

scholarly journals Long term outcomes of patients with chronic inflammatory diseases after percutaneous coronary intervention

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
E Marcusohn ◽  
R Zukermann ◽  
A Roguin ◽  
O Kobo
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Cox Regression ◽  
Inflammatory Diseases ◽  
Tertiary Care ◽  
Coronary Intervention ◽  
Long Term Outcomes ◽  
Chronic Inflammatory Diseases ◽  
Increased Risk ◽  
Percutaneous Coronary

Abstract Introduction Patients with chronic inflammatory diseases are at increased risk for coronary artery disease. Aim We aimed to assess the long-term outcomes of patients with chronic inflammatory diseases who underwent percutaneous coronary intervention. Methods A Retrospective cohort study of all adult (&gt;18 years) patients who underwent PCI in a large [1000 bed] tertiary care centerfrom January 2002 to August 2020. Results A total of 12,951 patients underwent PCI during the study period and were included in the cohort. The population of chronic inflammatory diseases includes 247/12,951 [1.9%]; 70 with IBD and 173 with AIRD. The composite endpoint of mortality, ACS or CHF admission was more frequent in the inflammatory disease group (77.5% in AIRD group, 72.9% in the IBD group and 59.6% in the non-inflammatory group, p&lt;0.001). The adjusted cox regression model found a statistically significant increased risk of the composite primary endpoints of around 40% for patients both with AIRD and IBD. The increased risk for ACS was 61% for AIRD patients and 37% for IBD patients. Patients with inflammatory diseases were found to have a significant increased risk CHF admission, while both IBD and AIED patients had a non-significant increased risk for mortality. Conclusion Patients with AIRD and IBD are at higher risk for cardiovascular events also in long term follow up once diagnosed with CAD and treated with PCI. FUNDunding Acknowledgement Type of funding sources: None.

Application of Plant-Based Preparations in a Comprehensive Treatment of Inflammatory Periodontal Diseases

2021 ◽  
Vol 6 (5) ◽  
pp. 38-44
Author(s):  
O. D. Saliuk ◽  
◽  
P. H. Gerasimchuk ◽  
L. O. Zaitsev ◽  
I. I. Samoilenko ◽  
...  
Keyword(s):  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
The Body ◽  
Comprehensive Treatment ◽  
Complex Treatment ◽  
Medicinal Products ◽  
Actual Problem ◽  
Periodontal Tissues ◽  
Wide Range ◽  
Anti Inflammatory

In this article the review of foreign and domestic literary sources, which are devoted to the actual problem of modern dentistry – the treatment of inflammatory diseases of periodontal tissues: gingivitis and periodontitis are presented. The complex approach to their treatment involves the appointment of a significant amount of pharmacotherapeutic drugs. Therapeutic failures and iatrogenic complications have led to the fact that today the interests of doctors and population to medicinal products significantly increased. The purpose of the study is to analyze the data of scientific literature on the use of plant-based medicinal products for the treatment of periodontal inflammatory diseases over the past 10 years. Materials and methods. Comprehensive and systematic analysis of literature. Review and discussion. The analysis of information sources on the use of plant-based medicinal products in dentistry both independently and in the composition of medical and prophylactic means has established that the modern assortment of plant-based preparations in the pharmaceutical market of Ukraine to a certain extent is limited. The emergence of new plant-based species that have been tested in conditions of experimental pathology and require an evidence-based clinical base is noted. The composition of plant-based preparations used for the treatment of inflammatory periodontal diseases include vitamins, biologically active substances, glycosides, alkaloids, in connection with a wide range of action: antiseptic, anti-inflammatory, regenerating, hemostatic, antioxidative. The data on plant-based preparations that are most often used such as chamomile extracts, calendula, hypericum, plantain, kalanchoe, aloe, eucalyptus, milfoil, nettle, calamus and plant-based species are summarized. The medicinal agents considered are mainly recommended for local treatment of periodontal diseases in the form of dental care means, mouth rinse, gel, chewing gum, herbal liquer. It is known that the complex treatment of periodontal diseases includes a general influence on the body. The properties of green tea with its wide range of actions are investigated. With antioxidant properties, it can be a healthy alternative for controlling destructive changes in periodontal diseases. Attention is drawn to the proposed unique natural complex “Resverazin” due to a wide range of pharmacological action, low toxicity and relative safety. The drug produces antioxidant, anti-inflammatory, immune stimulating, vasodilative, neuroprotective action. Conclusion. Based on the literature analysis, it can be concluded that the accumulated experimental and clinical data on the therapeutic properties of plants prove perspective of their use in the complex treatment of inflammatory periodontal diseases. Future studies are mandatory for further confirmation of the effectiveness of these medicinal plants

STUDY OF SPECIFIC PHARMACOLOGICAL ACTIVITY OF SODIUM SALT (4-О-Β-GLUCOPYRANOSYLOXY)-BENZOIC ACID

2016 ◽  
Vol 78 (6-8) ◽  
Author(s):  
Smirnov Ivan ◽  
Murashko Tatyana ◽  
Ivanov Alex ◽  
Bondarev Alex ◽  
Udut Vladimir
Keyword(s):  
Benzoic Acid ◽  
Analgesic Activity ◽  
Sodium Salt ◽  
Analgesic Effect ◽  
Inflammatory Diseases ◽  
Peptic Ulcers ◽  
Chronic Inflammatory Diseases ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Chronic inflammatory diseases of various genesis are prevalent today. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat pain and inflammation, but their long-term use is associated with complications in the gastrointestinal tract, including peptic ulcers. We synthesized a molecule of sodium salt (4-О-β-glucopyranosyloxy)-benzoic acid. This substance has diuretic and anti-inflammatory activities. It should be noted that most of NSAIDs has analgesic effect. In this connection, the aim of this study was to evaluate the analgesic activity of sodium salt (4-О-β-glucopyranosyloxy)-benzoic acid. We studied analgesic effect in the test “acetic writhing”. Sodium salt (4-О-β-glucopyranosyloxy)-benzoic acid significantly reduces the number of writhing by 14 units during the experiment, as an alternative criterion percent of animals with analgesia was 42.6%. Thus, in the test "acetic writhing" revealed the presence of the analgesic activity have developed drug average severity. 

Acute and long-term effect of infliximab on humoral and echocardiographic parameters in patients with chronic inflammatory diseases

2012 ◽  
Vol 32 (1) ◽  
pp. 61-66 ◽  
Author(s):  
Ľubomír Tomáš ◽  
Ivica Lazúrová ◽  
Lýdia Pundová ◽  
Mária Oetterová ◽  
Mária Zakuciová ◽  
...  
Keyword(s):  
Inflammatory Diseases ◽  
Term Effect ◽  
Chronic Inflammatory Diseases ◽  
Long Term Effect ◽  
Echocardiographic Parameters

scholarly journals Periodontal Tissues State and Psychophysiological Addiction: the Effectiveness of Treatment and Rehabilitation Complexes in Patients with Maxillofacial Area Injuries and Diseases

2016 ◽  
Vol 23 (3) ◽  
Author(s):  
A O Hryhorova
Keyword(s):  
Effective Treatment ◽  
Inflammatory Diseases ◽  
Clinical Monitoring ◽  
Complex Treatment ◽  
Treatment Need ◽  
Extended Treatment ◽  
Periodontal Tissues ◽  
Psychophysiological State ◽  
Treatment Individualization

The results of the clinical monitoring of patients with injuries and inflammatory diseases of maxillofacial area proved that the presence of nicotine psychophysiological addiction is a significant factor for the effective treatment of patients with maxillofacial area injuries, and in the case of extended treatment and rehabilitation complex greater efficiency is possible due to the reduction of periodontium treatment need by 27.6% in post-mobilization period. In patients with nicotine physiological addiction on the background of inflammatory diseases, in case of its use it is possible to achieve greater efficiency due to the reduction of the periodontium treatment need by 21.8%. Thus, diagnostics and consideration of the type of psychophysiological addiction can be considered as additional criteria of complex treatment individualization taking into account the psychophysiological state of patients in the course of prescribed treatment and rehabilitation complex application.

scholarly journals Late effects of antitumor treatment on the musculoskeletal system

2019 ◽  
Vol 6 (3) ◽  
pp. 86-93
Author(s):  
G. M. Muftakhova ◽  
N. A. Bolshakov ◽  
E. Yu. Ilyina
Keyword(s):  
Musculoskeletal System ◽  
Late Effects ◽  
The State ◽  
Limb Amputation ◽  
Malignant Neoplasms ◽  
Pathological Changes ◽  
Treatment And Prevention ◽  
Pathological Conditions ◽  
Long Term Consequences

This article is devoted to the analysis of problems associated with the state of the musculoskeletal system in patients who survived malignant neoplasms in childhood. The main diseases and pathological conditions that can develop in this population are considered. The risks of pathological changes in the musculoskeletal system, treatment and prevention are described. The issues of long-term consequences after limb amputation, organ-preserving operations, osteonecrosis, scoliosis, osteoporosis are separately analyzed.

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