scholarly journals LYMPHOEPITHELIAL CARCINOMA OF PARANASAL SINUS: A RARE CASE REPORT AND REVIEW OF LITERATURE

2020 ◽  
Vol VOLUME 8 (ONE) ◽  
pp. 39-42
Author(s):  
B.R. Gyawali

Background: Lymphoepithelial carcinoma is one the rare tumor of nose and paranasal sinus with only few cases reported so far. Epidemiology, etiopathogenesis, modes of presentation and the management of this condition still remain elds to be explored. Case Presentation: A 55 years old lady presented with right sided nasal obstruction with nasal discharge for 2 years. Nasal endoscopy showed multiple pinkish, polypoidal mass almost lling whole of right nasal cavity. Imaging study showed soft tissue density with hyperdense area in right ethmoid and sphenoid sinuses. Biopsy of the lesion revealed Lymphoepithelial carcinoma. Patient was managed by endoscopic debulking followed by radiotherapy. There was no evidence of tumor on follow up evaluation, six months after radiotherapy. Conclusion: Lymphoepithelial carcinoma can affect nose and paranasal sinuses. Although, a consensus on management of the disease is yet to be achieved, the best management so far is surgery followed by an adjuvant radiotherapy. Key words: paranasal sinus neoplasm, sphenoid sinus, ethmoid sinus

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Jai Kumar ◽  
Mohammad Irfaan Albeerdy ◽  
Nadeem Ahmed Shaikh ◽  
Abdul Hafeez Qureshi

Abstract Background Peutz-Jeghers syndrome is an autosomal dominant disease characterized by mucocutaneous pigmentation and hamartomatous polyps in the gastrointestinal tract (GIT). There have also been cases of extra GIT polyps such as the renal pelvis, urinary bladder, lungs and nares. Bladder hamartoma is an extremely rare finding, with only 12 cases described in the literature up to now. The rarity of the condition necessitates a comprehensive compilation of managements up to now so as to provide a better tool for the treatment of such conditions in the future. Case presentation A twenty-year-old male, known to have Peutz-Jeghers syndrome, presented to us complaining of obstructive urinary symptoms. A urethrogram done showed a filling defect at the base of the urinary bladder. The mass was resected transurethrally, and histopathology revealed a hamartoma of the bladder. The patient has since remained tumor-free on follow-up. Conclusions Transurethral resection of the bladder mass proved to be an effective therapy in this patient with no recurrence on the patient’s follow-up till now. There is still, however, a dearth of knowledge regarding the management of bladder hamartomas owing to the extreme rarity of the case.


2021 ◽  
Vol 37 (1) ◽  
Author(s):  
Anup Singh ◽  
Vaisakh Kuzhikkali ◽  
Arvind Kumar Kairo

Abstract Background Head and neck is a relatively common site of occurrence for the peripheral nerve sheath tumors, and majority of these tumors are seen involving neck, involving vagus nerve, and cervical sympathetic chain. Schwannomas involving mobile tongue are rarely encountered, especially in the pediatric population Case presentation We present a case of recurrent tongue schwannoma in a 13-year-old female successfully managed with transoral excision. At a follow-up of 3 years, no recurrence is observed. Conclusion Surgical excision is the recommended modality of treatment for lingual schwannomas, and when excised adequately, recurrences are not expected. A clear margin of surrounding normal tissue should be aimed for to avoid possible recurrence.


2017 ◽  
Vol 9 (04) ◽  
pp. 322-324
Author(s):  
Saha Arpita ◽  
Jain Manoj ◽  
Saha Kaushik ◽  
Srivastava Anish

AbstractMetachronous metastatic renal cell carcinoma (RCC) to bladder is rare incidence. We report a case of RCC with metachronous metastasis to the urinary bladder occurring 2 years postradical nephrectomy. In a follow‑up for the past 1 year, the patient is doing well. To the best of our knowledge, this case is the second case of bladder metastasis from RCC in the Indian literature. We reviewed literature and discuss the histopathological features of bladder metastasis of RCC.


Author(s):  
Carmen Bustamante ◽  
Alfonso Hoyos-Martínez ◽  
Daniela Pirela ◽  
Alejandro Díaz

AbstractBackground:Krukenberg tumors are ovarian metastatic adenocarcinomas with a primary origin usually located in the stomach, colon, gallbladder, pancreas, or breast. Occasionally, these tumors produce virilization in the affected individual due to androgen production by luteinization of the tumoral stroma. It is believed that during pregnancy these tumors are more likely to increase androgen production due to the elevated levels of human chorionic gonadotropin (hCG). High maternal androgens can cross the placenta producing virilization of the female fetus.Case presentation:A 46,XX newborn female, whose mother was diagnosed with a metastatic ovarian tumor during her second trimester of gestation associated with worsening hirsutism and acne, was found to have ambiguous genitalia at birth. Testosterone levels in both the mother and infant were elevated. Follow-up laboratory tests showed progressive normalization of circulating androgens after delivery.Conclusions:Krukenberg tumors are rare and may produce virilization of the mother and the female fetus when present during pregnancy.


2020 ◽  
Author(s):  
Tao Yang ◽  
Lanqing Cao ◽  
Wei Li ◽  
Kai Zhang ◽  
Yuecheng Zhu ◽  
...  

Abstract Background:There are few reports of large retroperitoneal schwannomas and few guidelines for the diagnosis and surgical treatment.Case presentation:A 40-year-old female came to our department due to abdominal pain for 1 day and there are no other specific symptoms. There were no abnormalities in the patient's tumor markers. Plain computer tomography (CT) scan of the whole abdomen revealed two mass soft tissue density shadows behind the peritoneum, with uneven internal density, cystic low-density shadows and patchy calcification shadows. The larger mass was about 12.0 cm × 12.3 cm in size. Then tumors were completely excised by a reasonable surgical approach while the surrounding organs closely related to the tumor were preserved. Postoperative pathology confirmed that the tumor was benign schwannoma. In the 18-month follow-up, the patient had no recurrences and was asymptomatic.Conclusion:We summarize the diagnosis and treatment of a rare giant retroperitoneal schwannoma. Laparotomy for the management of retroperitoneal giant schwannomas may be a safe and effective method.


2019 ◽  
Vol 11 (2) ◽  
pp. 104-106
Author(s):  
Eyad Darraj

Radiation-induced sarcoma in the head and neck is a long-term rare complication of radiation therapy, with an estimated risk of up to 0.3%. The incidence of these sarcomas is, however, likely to increase due to the progressive aging of the population combined with improved survival in head and neck cancer patients resulting from better treatment regimes. This is a case of post -radiation sarcoma of the hypopharynx radiated for tongue carcinoma previously. This case is reported to high light a rare but devastating complication of radiotherapy that is to be kept in mind during follow up.


2021 ◽  
Author(s):  
Xiao Wei ◽  
Attigah S. D. Kwasi ◽  
Qi Li ◽  
Hongyan Wu ◽  
Jun Chen ◽  
...  

Abstract Background: Plexiform fibromyxoma (PF) is a very rare mesenchymal tumor of the stomach. Here we report one case of this unusual gastric tumor that was pathologically confirmed after endoscopic resection. Its clinical and pathologic features were observed while the relevant literature was reviewed. Case presentation: A 1.0 cm round elevated submucosal mass was discovered by gastroscopy in a 44-year-old Chinese woman due to recurrent abdominal pain. The tumor was characterized by a multinodular plexiform pattern, bland-looking oval to spindle cells, and a myxoid stroma with thin arborizing capillaries. Immunohistochemistry analysis revealed that the tumor cells were positive for smooth muscle actin (SMA) and negative for CD117, DOG-1, CD34, Desmin, progesterone receptor (PR), CD10, S100 and SOX10. A diagnosis of PF was rendered.Conclusion: Gastric PF is a benign tumor without evidence of local recurrence and distant metastasis. This case emphasizes the unique histological appearance and immunophenotype of PF to promote early diagnosis, while endoscopic resection can be used as an alternative treatment for small and superficial PF.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yannan Wang ◽  
Feiya Zhu ◽  
Kai Wang

Abstract Background Head and neck Synovial sarcoma (SS) accounts for 3–10% of all total body SS. It is rare to find it in the oral cavity, especially on the floor of the mouth. Case presentation We present a 44-year-old Chinese male, who had been misdiagnosed as fibroadenoma, with a swelling on the right submandibular region for more than 3 months. The radiology examinations and the pathology results indicate the diagnosis of SS of the floor of the mouth. The patient only had a surgical operation, without radiotherapy and chemotherapy. At the first follow-up, the patient exhibited no clinical or radiographic complications, and the patient was asymptomatic on subsequent visits. Conclusions Misdiagnosis results the delay of diagnosis and treatment of SS. Immunohistological analysis might be the most important tool to confirm the diagnosis of SS.


2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Cong Jin ◽  
Minghua Xie ◽  
Wengqing Liang ◽  
Yu Qian

Abstract Background Osteoradionecrosis (ORN) is a complication that occurs after radiotherapy for head or neck malignancies. ORN of the spine is rare, with only few cases affecting the cervical spine reported to date. To our knowledge, no case of lumbar ORN has been reported. We report a rare case of ORN in the lumbar spine that occurred 2 years after radiotherapy and perform a literature review. Case presentation We present a case of lumbar ORN that occurred 2 years after radiotherapy for gallbladder carcinoma. The patient was successfully treated conservatively and followed up for > 10 years. Conclusions ORN of the spine is a rare complication of radiotherapy. Spinal ORN is clinically described as a chronic disease with a slow onset. The most common presenting symptom of spinal ORN is pain. However, as ORN progresses, spinal kyphosis and instability can lead to neurological compression and thus to induced myelopathy or radiculopathy. Treatment of spinal ORN is comprehensive, including orthosis, medication, hyperbaric oxygen therapy, surgery, and new treatment combinations of pentoxifylline and tocopherol. The surgical rate for spinal ORN is relatively high.


BMC Urology ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Ming Liu ◽  
Ting-Shuai Zhai ◽  
Xiao-Feng Zhao ◽  
Li-Jin Feng ◽  
Xin-Sheng Lyu ◽  
...  

Abstract Background Aggressive angiomyxoma (AA) is a rare tumor that typically occurs in the pelvis and perineum, most commonly in women of reproductive age. However, no para-ureteral AA has been reported according to the literature. Case presentation We herein describe the first case of para-ureteral AA. A 62-year-old male presented to our institute in March 2017 with a para-ureteral mass that was 15 mm in diameter incidentally. No symptom was observed and laboratory analysis was unremarkable. Magnetic resonance and computed tomography imaging showed a non-enhancing mass abutting the left ureter without causing obstruction. Laparoscopic resection of the mass was performed without injury to the ureter. Pathologic and immunohistochemical results were consistent with AA. Till now, no recurrence was noticed. Conclusions We reported a rare case of para-ureteral AA, along with a literature review. Early diagnosis, proper surgical plan and long-term close follow-up is recommended for its high risk of recurrence and malignant potential.


Sign in / Sign up

Export Citation Format

Share Document