scholarly journals PHYSICAL INDICES OF THE ORAL FLUID IN CHILDREN WITH CARIES AND INTACT TEETH AT DIFFERENT AGE PERIODS

2019 ◽  
Vol 72 (5) ◽  
pp. 1048-1052
Author(s):  
Lyudmila F. Кaskova ◽  
Тetyana B. Маndziuk ◽  
Larissa P. Ulasevych ◽  
Natallia B. Kuzniak
Keyword(s):  
Oral Cavity ◽  
Oral Fluid ◽  
Permanent Teeth ◽  
Fluid Viscosity ◽  
Dental Tissues ◽  
Dental Examination ◽  
Dental Diseases ◽  
The Common ◽  
Carious Process ◽  
Hard Dental Tissues

Introduction: Caries occurs most frequently among dental diseases of the hard dental tissues in children. Its occurrence and intensity do not decrease, although scientists and practitioners make much efforts directed to the reduction of these indices The aim: Therefore, the objective of our study was to investigate the indices of rate salivation and viscosity of the oral fluid in children at different age periods with caries and intact teeth. Materials and methods: 134 children, 7-9 years old, and 89 children,10-12 years old, studying at Poltava schools were examined. Dental examination was conducted according to the common methods. Caries intensity in all the children was determined by Caries Filling Extraction (CFE) Index, and CFE+cfe. To determine salivation rate the oral fluid was collected on empty stomach in the morning into sterile calibrated tubes during 5 minutes. Results and conclusions: Investigations of physical indices of the oral fluid in children of 7-9 and 10-12 years of age did not find their reliable difference considering the child’s age. Meanwhile the indices of salivation rate and oral fluid viscosity in children with caries and without it were found to differ much. That is, the course of carious process in children is associated with reduced salivation rate and increased index of the oral fluid viscosity, which in its turn deteriorates hygienic state of the oral cavity enabling to activate the activity of dental deposit microflora and its effect on enamel demineralization followed by occurrence of carious defect of temporary and especially permanent teeth recently erupted and poorly mineralized. The results obtained were calculated by variation statistics method. The indices were considered to be reliable with р≤0,05.

Laser-Induced Fluorescence and X-Ray Spectral Analysis of Carious Process in Hard Dental Tissues

2010 ◽  
Vol 149 (3) ◽  
pp. 373-376 ◽  
Author(s):  
G. Yu. Lidman ◽  
P. M. Larionov ◽  
S. V. Savchenko ◽  
E. L. Lushnikova ◽  
A. M. Orishich ◽  
...  
Keyword(s):  
Spectral Analysis ◽  
Laser Induced Fluorescence ◽  
X Ray ◽  
Dental Tissues ◽  
Carious Process ◽  
Hard Dental Tissues

scholarly journals PREVENTION OF DENTAL CARIES IN THE CONDITIONS OF ECOLOGICAL POLLUTION

2018 ◽  
pp. 55-59
Author(s):  
I.V. Kovach ◽  
H.V. Shtompel ◽  
Ye.N. Dychko ◽  
A.V. Verbytska
Keyword(s):  
Dental Caries ◽  
Oral Cavity ◽  
Dental Health ◽  
Harmful Effect ◽  
Living Environment ◽  
Preschool Age ◽  
Permanent Teeth ◽  
Control Group ◽  
Basic Group ◽  
Dental Tissues

Modern domestic preventive dentistry has success in the theory of the origin and development of major dental diseases, practice of treatment, including dental caries, and uses these results to prevent children’s diseases in the country. However, the desired effectiveness of preventive measures have not been achieved primarily among the population and individual level, taking into account some specific characteristics of residence region, etiology and pathogenesis of the demineralization phenomena of hard dental tissues in different periods of child’s development. Adverse environmental conditions and technogenic character are not taken into account, when air, soil and groundwater are oversaturated with environmental contaminants and toxicants. They cause fatal breakage in biochemical reactions and metabolic processes in childhood and at a young age, when defective dental health brings a lot of problems in the adult period of life, and, as a result, reduces the life. Investigation of dental health had been conducted in 251 preschool age children (first age group consisted of 3-4 years-old, II group consisted of 5-6 – years-old with 123 and 128 people respectively). In addition, all the observed children were divided into two groups depending on the use of prophylactic anti-caries interventions: the basic group was in compliance with the "Program- maximum" and control the "Program- minimum". Approximately 60 members were in the monitoring teams of different age groups. The "Program-minimum" included measures of general health, balanced diet with the significant restriction of carbohydrate and perform twice a day hygiene actions in the oral cavity. The “Program – maximum” also included the ingestion of calcium citrate and amino acids with SH-group of methionine. Such treatment and prophylactic complex has the adaptive, antioxidant, antidote and immune resolving action. It makes sense for neutralization of eco toxicants – heavy metals in the area of children’s residence. It was found that level of Fe and Zn was in the threatening degree of content, and Cd is moderate in the living environment of the examined children. It provokes and enhances the glycolytic processes in the oral cavity. Harmful effect of toxicants in the oral cavity, and also in a children's organism as a whole, was clearly fixed in the mineralization of the skeleton flat bones of children. It was revealed with densitometry of the calcaneus that 53 individuals had  indicators, particularly BUA. They indicated the weakening of the skeleton mineralization. It indirectly pointed to problems in the hard tissues of the teeth. However, the use of treatment and prophylactic complex improved the bone structures density. The level of calcium and phosphate in the oral fluid of the observed individuals had recovered to optimal after three years of use of treatment and prophylactic complex, contributed to effective secondary mineralization both in temporary and in permanent teeth. Thus, the use of treatment and prophylactic complex in people of the basic group allowed quite convincingly and positively to impact on the incidence of caries of deciduous and permanent teeth. The rate of growth of dental caries intensity after three years of preventive interventions in the basic group was three times less than in the control group. At the same time, the caries preventive efficacy was 59-62%, and this is a very positive indicator. These results are evidence of proven necessity of prophylactic of dental health correction in children years of those people who reside in areas with a very complex technogenic environment due to metallurgical plants located in the Prydniprovsk region.

scholarly journals TACTICS OF DENTAL EXAMINATION OF WOMEN WITH PERIODONTAL DISEASE AGAINST THE BACKGROUND OF BACTERIAL VAGINOSIS AND THEIR SEXUAL PARTNERS

2020 ◽  
Vol 20 (2) ◽  
pp. 206-210
Author(s):  
A.D. Krutikova
Keyword(s):  
Oral Cavity ◽  
Bacterial Vaginosis ◽  
Oral Fluid ◽  
Periodontal Diseases ◽  
Sexual Partners ◽  
Gardnerella Vaginalis ◽  
Dental Examination ◽  
Initial Stage ◽  
Periodontal Index ◽  
Atopobium Vaginae

Numerous studies have proved that periodontal pathology is an issue that requires a comprehensive and multidisciplinary approach in diagnosis, treatment and prevention, as most periodontal diseases are syndromic manifestations of somatic and psycho-somatic diseases, but there are little data on the periodontal status in patients with disturbance of the genital microflora. The aim of the study was to provide the grounds for the tactics of dental examination of child-bearing women with bacterial vaginosis and their sexual partners and to compare the results of different sex groups. Materials and methods. 28 heterosexual couples aged 18-45 years were examined. Objective periodontal examination included the calculation of Green-Vermilion oral hygiene index, papillary-marginal-alveolar index, complex periodontal index by P.A. Leus, Svrakov's iodine number. Amino test of oral fluid, assessment of oral fluid pH, identification of bacterial vaginosis pathogens, and in particular, Gardnerella vaginalis and Atopobium vaginae, in the oral cavity of the patients by polymerase chain reaction-diagnostics and bacterioscopically. Results. Chronic generalized catarrhal gingivitis was detected in 10.71% of the women, chronic generalized periodontitis in the initial stage was found out in 64.29% of the women, and chronic generalized periodontitis of the first degree in 25% of the female patients. Men, who were carriers of bacterial vaginosis, chronic generalized catarrhal gingivitis, made up 7.14%; chronic generalized periodontitis in the initial stage was found in 60.71% of the men and chronic generalized periodontitis was found in 32.14%. The values ​​of periodontal indices did not really differ between the indicators of different sex groups. Amino tests of the oral fluid in the women and men showed a positive result those points out the presence of volatile amines. The oral fluid pH is reduced in patients of both groups that indicate an inflammatory process in the oral cavity. All the patients have "key cells", which are exfoliated epitheliocytes with Atopobium vaginae and Gardnerella vaginalis adhered to them. This is one of the main markers of bacterial vaginosis. Conclusions. Summing up the results of the performed clinical and laboratory observations, it should be noted that when collecting the history of bearing aged women, the dentist should pay attention to the presence of diseases of the genital tract, and in particular, bacterial vaginosis. To detect inflammatory and inflammatory-dystrophic periodontal diseases in women of childbearing age, amino tests of oral fluid not only in women but also in their sexual partners for rapid diagnosis of pathogens such as bacterial vaginosis and vaginal vaginal vagina can be very informative.

Characteristics of Trace Element Balance in Children with Pollution-Related Dental Diseases

2021 ◽  
pp. 44-48
Author(s):  
NP Setko ◽  
IT Mustafin
Keyword(s):  
Trace Elements ◽  
Anthropogenic Factors ◽  
Environmental Toxicants ◽  
Industrial Chemicals ◽  
Dental Tissues ◽  
Essential Trace Elements ◽  
Dental Diseases ◽  
Hard Dental Tissues ◽  
High Level ◽  
Carious Teeth

Summary. Introduction: The necessity to assess, prevent and correct element-dependent diseases, increase the level of safety, predict and reduce the risk of exposures to industrial contaminants in the development of dental diseases in the child population is an important and promising area of modern hygiene. The objective of our study was to establish concentrations of trace elements in dental tissues of children exposed to various levels of industrial pollution. Materials and methods: We used atomic absorption spectrophotometry to measure 13 trace elements in extracted healthy and carious primary teeth in two groups of children aged 7–11. The first group consisted of 56 children living in the area with a significantly high level of anthropogenic burden (Caveraged total = 1.17 units) and a high prevalence of caries (86.9 %) while the second group consisted of 68 children living in the area with a relatively high level of anthropogenic burden (Caveraged total = 0.68 units) and a mean prevalence of caries (77.1 %) according to WHO criteria. Results: Our findings indicate that accumulation of toxic microelements in hard dental tissues of children in the first group was higher than in children of the second group: concentrations of lead, bismuth, cadmium and strontium were 2.6, 1.8, 2.5, and 1.2 times higher, respectively. We also observed higher accumulation of environmental toxicants in carious teeth compared to healthy ones. Thus, lead, cadmium and bismuth levels in carious teeth were 3.04, 1.2 and 3.13 times higher than in healthy teeth, respectively, while the level of strontium was, on the opposite, 2.5 times lower. Conclusions: The study revealed specific features of the interaction of essential trace elements in children in the form of antagonistic effects between cadmium and zinc, copper and manganese, and synergism in the content of copper, iron, nickel, zinc, and cobalt in healthy teeth, the mechanism of which is based on competition for a bond with a carrier substance and replacement of one element with another. In addition, we established that changes in the microelement balance in the hard tissues of healthy and carious teeth are not unidirectional in nature, thus reflecting complex interactions between the child’s organism and anthropogenic factors. The results proved that accumulation of toxic trace elements in hard dental tissues promotes caries development and causes a sharp decrease in the content of essential trace elements, especially chromium, manganese, iron, and copper. The study showed that hard dental tissues are a depot for lead, cadmium, bismuth, and strontium in children environmentally exposed to high levels of industrial chemicals. Features of developing an imbalance of biotic concentrations of essential elements and accumulating toxic microelements in children with pollution-related tooth pathology were also established.

scholarly journals ANALYSIS OF VNTR POLYMORPHISM OF MUC5B GENE IN CONNECTION WITH CERTAIN PHYSICO-CHEMICAL PROPERTIES OF ORAL LIQUID IN CHIL-DREN WITH DOWN SYNDROME

2017 ◽  
Vol 4 (4) ◽  
pp. 211-217
Author(s):  
R. Nazaryan ◽  
O. Iskorostenskaya ◽  
O. Gorenskaya ◽  
N. Volkova
Keyword(s):  
Down Syndrome ◽  
Oral Cavity ◽  
Oral Fluid ◽  
Chemical Properties ◽  
Fluid Viscosity ◽  
Chromosome 11 ◽  
Protective Function ◽  
Mucous Membranes ◽  
Microbial Environment ◽  
Ph Level

Protective function of oral fluid is evident in maintaining constant saliva volume, moisturizing mucous membranes of the oral cavity, teeth enamel, preventing the defeat of soft and hard tissues of the oral cavity by pathogenic microorganisms. A number of factors, called "barriers of colonization", specifically and nonspecifically manage the process. What matters most is "mucous block”, which characterizes the set of mechanical, humoral, nonspecific factors of protecting mucous membranes against microorganisms. Mucin proteins which are the main glicoproteine saliva components affect the creation and selection of biofilm microflora, facilitating or inhibiting the adhesion of microorganisms and maintaining healthy microbial environment in the oral cavity. The dominant mucin of submucosa glands is MUC5B, which is encoded by the same gene, located in a short shoulder of segment 15.5 of chromosome 11. Changes of the basic physical and chemical properties of nonstimulated saliva in children with Down syndrome, namely, reduction of pH level and increasing oral fluid viscosity, is certainly an important prerequisite for formation of cariogenic situation.Keywords: Down syndrome, MUC5B, oral cavity, saliva.  АНАЛІЗ ПОЛІМОРФІЗМУ VNTR ГЕНУ MUC5B У ЗВ'ЯЗКУ З ДЕЯКИМИ ФІЗІКО-ХІМІЧНИМИ ВЛАСТИВОСТЯМИ РОТОВОЇ РІДИНИ У ДІТЕЙ З СИНДРОМОМ ДАУНА.Назарян Р.С., Іскоростенська О.В., Горенська О.В., Волкова Н.Є. Захисна функція ротової рідини проявляється у підтриманні постійного об'єму слини, зволоженні слизової оболонки ротової порожнини, емалі зубів, запобіганні ураження м'яких і твердих тканин ротової порожнини патогенними мікроорганізмами. Цілий ряд факторів, що їх називають "бар'єрами колонізації", специфічно та неспецифічно керує процесом. Найбільше значення при цьому має "мукозний блок”, який характеризує комплекс механічних, гуморальних, не специфічних факторів захисту слизової оболонки від мікроорганізмів. Білки-муцини, які є основними глікопротеїновими компонентами слини, впливають на створення і вибір мікрофлори біоплівки, полегшуючи або попереджаючи адгезію мікроорганізмів і підтримуючи здорову мікробну середу ротової порожнини. Домінуючим муцином залоз підслизового слою є MUC5B, який кодується однойменним геном, розташованим у короткому плечі сегмента 15.5 хромосоми 11. Зміни основних фізико-хімічних властивостей нестимульованої слини у дітей з діагнозом синдром Дауна, а саме зменшення рівня рН і підвищення рівня плинності ротової рідини, безумовно є важливою передумовою для утворення карієсогенної ситуації.Ключові слова: MUC5B, ротова порожнина, синдром Дауна, слина. АНАЛИЗ ПОЛИМОРФИЗМА VNTR ГЕНА MUC5B В СВЯЗИ С НЕКОТОРЫМИ ФИЗИКО-ХИМИЧЕСКИМИ СВОЙСТВАМИ РОТОВОЙ ЖИДКОСТИ У ДЕТЕЙ С СИНДРОМОМ ДАУНА.Назарян Р.С., Искоростенская О.В., Горенская О.В., Волкова Н.Е. Защитная функция ротовой жидкости проявляется в поддержании постоянного объёма слюны, увлажнении слизистой оболочки полости рта, эмали зубов, предотвращении поражения мягких и твердых тканей ротовой полости патогенными микроорганизмами. Ряд факторов, называемых «барьерами колонизации», специфически и неспецифически управляет данным процессом. Наибольшее значение при этом имеет «мукозный блок», характеризующий комплекс механических, гуморальных, неспецифических факторов защиты слизистой оболочки от заселения ее микроорганизмами. Белки-муцины, которые являются основными гликопротеиновыми компонентами слюны, влияют на создание и выбор микрофлоры биопленки, облегчая или препятствуя адгезии микроорганизмов и поддерживая здоровую микробную среду в полости рта. Доминирующим муцином желез подслизистого слоя является который кодируется одноименным геном, расположенным в коротком плече сегмента 15.5 хромосомы 11. Изменения основных физико-химических свойств нестимулированной слюны у детей с диагнозом синдром Дауна, а именно снижение уровня рН и повышение уровня тягучести ротовой жидкости, является, безусловно, важной предпосылкой для формирования кариесогенной ситуации.Ключевые слова: MUC5B, полость рта, синдром Дауна, слюна.

scholarly journals GENERAL FEATURES OF CARIES PATHOGENESIS IN THIRD MOLARS AND AUTOIMMUNE DISEASES

2020 ◽  
Vol 20 (3) ◽  
pp. 211-216
Author(s):  
R. V. Talash
Keyword(s):  
Autoimmune Diseases ◽  
Pathogenic Bacteria ◽  
Third Molars ◽  
Initial Manifestation ◽  
Dental Tissues ◽  
Tissue Degeneration ◽  
Autoimmune Pathology ◽  
Carious Process ◽  
Hard Dental Tissues ◽  
Initial Source

This article presents a literature review, the results of the analysis of random samples of third molars removed for various clinical indications (11 samples). The teeth samples were analyzed visually, then their coronal parts were treated with epoxy plastination technique and prepared polished sections were studied microscopically. The analyzed data demonstrate the pathogenesis of fissure caries in our samples studied can be explained in terms of the direct virulent effect of pathogenic bacteria on the organic matter in the superficial dentin and basal enamel with the formation of auto antigens, which, as a result of sensitization of the local immune system, become the initial source of the carious process spreading to other teeth. This gives grounds to identify it with the pathogenesis of autoimmune pathology. It has been established that carious damage to hard tissues on the smooth surfaces of the dental crown begins with the pulp, when it is vital, and stops as a result of its tissue degeneration. It has been shown that a single latent damage to the hard dental tissues is the initial manifestation of the latent stage of the carious process, while multiple defects indicate its further progression. As for the generally accepted classification of caries, according to which superficial, medium and deep caries are distinguished, then, in our opinion, they should be considered as stages of the further process of carious destruction of hard dental tissues. We can suggest the study of the pathogenesis of carious lesions of third molars is necessary in order to prevent the occurrence of autoimmune diseases and increase the effectiveness of their treatment.

scholarly journals Improving the effectiveness of secondary prevention caries in women during pregnancy

2020 ◽  
Vol 18 (3) ◽  
pp. 4-9
Author(s):  
Zh. V. Solovyeva ◽  
E. S. Zaporozhskaya-Abramova ◽  
A. A. Adamchik ◽  
T. F. Kosyreva ◽  
T. V. Shkirya
Keyword(s):  
Oral Cavity ◽  
Pregnant Women ◽  
Oral Hygiene ◽  
Control Group ◽  
Dental Tissues ◽  
Prophylactic Measures ◽  
Working Groups ◽  
Hard Dental Tissues ◽  
Long Acting ◽  
Medical University

Aim. To evaluate the clinical efficacy of long-acting remineralizing medical means in the complex prevention of caries in pregnant women.Materials and methods. The study was conducted on the basis of the Department of Therapeutic Dentistry of the Kuban State Medical University of the Ministry of Health of Russia. A total of 87 people were examined, aged 24 to 37 years, with different levels of oral hygiene 84 patients confirmed their consent to the treatment and prophylactic measures, after which three working groups were formed depending on the long-acting remineralizing agents used “Clinpro-XTVarnish” manufactured by 3MESPE, “Schmelz-versiegelungsliquid” manufactured by HUMANCHEME, “InnoDent Repair” manufactured by InnoDent LLP respectively) and 1 control group. The assessment of the dental status of pregnant women was carried out using indices: CFE, Fedorov-Volodkina oral hygiene index (HI), gingivitis index GI (Loe H., Silness J.).Results. According to the data of a clinical study, it was determined that a high quality oral cavity sanitation with concomitant use of long-acting therapeutic and prophylactic agents increases the effectiveness of preventive measures in pregnant women.Conclusions. The data obtained indicate the achievement of a long-term preventive result, which makes it possible to recommend the investigated fluorine-containing agents for remineralization of hard dental tissues in order to control the state of the oral cavity of women during pregnancy.

Correlations Between pH Values of Oral Fluid and Dental Caries Epidemiologic Indicators in Children Aged within 6-12 Years

2018 ◽  
Vol 69 (2) ◽  
pp. 484-487
Author(s):  
Andreea Simona Pop ◽  
Radu Septimiu Campian ◽  
Paula Jiman ◽  
Ecaterina Ionescu ◽  
Stefan Milicescu ◽  
...  
Keyword(s):  
Dental Caries ◽  
Oral Fluid ◽  
Permanent Teeth ◽  
Deciduous Teeth ◽  
Ph Indicator ◽  
Significant Statistical Difference ◽  
Ph Values ◽  
Carious Process ◽  
Dental Surface ◽  
Made In

The aim of this study was to evaluate the correlations between the pH values of oral fluid and the epidemiologic indicators of dental caries in children aged between 6-12 years. Clinical examinations were performed on 1517 children and the analysis was made in groups of 6-8 years old (n=701) [male (n=353), female (n=348)], and 9-12 years old (n=786) [male (n=426), female (n=360)]. The research included the record the pH values of the oral fluid and clinical examinations for evaluation of the state of oral health, in conformity to the codes of the OMS carious affection level. For the determination and the record of pH values of the oral fluid we used GC Saliva pH Indicator kit. The study followed defs, deft, dmfs, dmft epidemiologic indices of dental caries. The determined values of oral fluid pH were between 5.0 and 6.4. The obtained values of indices in all studied groups and subgroups demonstrated the significant statistical difference between at least two values (p [ 0.001). 72% of the studied group presented with at least a dental surface affected in deciduous teeth, while only 40% of the children presented a carious process on the permanent teeth. The occlusal surface was the most frequently affected by dental caries, followed by the proximal surfaces (mesial and distal) and last being smooth surface caries. The study demonstrated the correlation between acidic values of oral fluid pH and the dental caries in the study group.

Dental mask of gastroesophageal reflux disease

2021 ◽  
pp. 18-22
Author(s):  
T.A. Smirnova ◽  
O.A. Novozhilova ◽  
A.V. Kochubeynik ◽  
D.V. Smirnov
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Oral Cavity ◽  
Oral Mucosa ◽  
Reflux Disease ◽  
Average Score ◽  
Dental Tissues ◽  
Carious Lesions ◽  
Hard Dental Tissues ◽  
Methods Of Treatment

In clinical practice, there are patients for whom traditional methods of treatment do not allow getting rid of a dental disease. Dental mask of underlying pathology may be a potential cause of this. The aim of the study was to study the features of the clinical course of dental manifestations of gastroesophageal reflux disease. Methods. The study group included 45 patients aged 20 to 50 years with complaints of pathological changes in the oral cavity that did not stop during the last month. The survey included a survey and clinical examination. The GerdQ questionnaire was used to verify gastrointestinal disorders. Results. It was found that 85% of the surveyed complained of a burning sensation behind the breastbone, the ingress of acidic contents into the oral cavity. 100% of the surveyed presented dental complaints. At the same time, the frequency of dental complaints was significantly higher compared to the frequency of complaints of esophageal symptoms. According to the results of the GerdQ questionnaire, the average score among the subjects was 11.0, which corresponds to the presence of gastroesophageal reflux disease. According to the results of the dental examination, 87% of the examined patients had pathological elements on the oral mucosa, and the pathological elements of aphthous and herpetic stomatitis were found significantly more often in patients with an exacerbation of gastroesophageal reflux disease (p<0.05). Desquamative glossitis was detected in 33% of the examined patients, benign migratory glossitis (“geographical” tongue) in 59% of patients, exfoliative cheilitis (dry form) in 70% of patients, angular cheilitis in 23% of patients. The pathology of hard dental tissues was represented by multiple carious lesions in 75% of patients and non-carious lesions in 53% of patients. Conclusions. Diseases of the oral mucosa and non-carious lesions accompany patients with gastrointestinal tract pathology in the form of gastroesophageal reflux disease.

scholarly journals Individual prediction of development of cervical dental tissue pathology based on the parameters of oral fluid

2020 ◽  
Vol 24 (4) ◽  
pp. 624-628
Author(s):  
I. I. Zabolotna
Keyword(s):  
Chemical Composition ◽  
Young People ◽  
Oral Fluid ◽  
Predictive Accuracy ◽  
Subsequent Development ◽  
The State ◽  
Risk Level ◽  
Cervical Lesions ◽  
Dental Tissues ◽  
Hard Dental Tissues

Annotation. Significant prevalence of cervical lesions of hard dental tissues is the reason for the search for the ways to predict their development that is possible only with an individual approach to solving this problem. The aim of the study is to determine the chemical composition of the patients’ oral fluid with clinically intact hard tissues, cervical caries and wedge-shaped defect, identify its critical values and the subsequent development of the method for individual prediction of the onset of pathology in young people. To accomplish it we used JSM-6490 LV focused beam electron microscope (scanning) to determine the chemical composition of the enamel and dentin of 29 teeth and their longitudinal sections, the chemical composition of the oral fluid of 33 patients who were divided into three groups depending on the state of their hard dental tissues. The approbation of the proposed method was carried out in 45 young people, the results were compared with the data of the clinical examination of 42 patients a year later. To verify the relationship between the variables, the Pearson parametric correlation method was used based on the determination of the Brave-Pearson parametric coefficient (r) with a 95% confidence level. The reliability of the obtained results was evaluated by Student's t-test, the correlation between indicators – by Student’s test using the Z-test (Fisher’s z-test). The level of significance of differences at p≤0.05 was considered statistically significant. It was determined that the values of the Ca+Na+Mg/P coefficient in enamel, dentin and oral fluid significantly differed depending on the state of hard dental tissues (p≤0.05). Moderate and high inverse correlation was revealed between Ca/P and Ca+Na+Mg/P coefficients in cervical enamel and oral fluid (p≤0.05). Obtained results became the basis for the development of the method for individual prediction of the onset of cervical pathology in young people: with the values of the Ca+Na+Mg/P coefficient higher than 22 – a low level, from 11 to 22 – an average level, lower than 11 – a high risk level. Thus, we have proved that the proposed method is informative (the predictive accuracy reaches 85%), its non-invasiveness is the basis for its widespread use. We consider the search for the ways of individual prediction of the development of cervical caries and wedge-shaped defect in young people based on the parameters of the oral fluid to be promising.

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