Mechanisms and substances involved in clastic activity of root resorptions – literature review

Aim: to research through literature review, the mechanisms involved in the establishment of root resorptions. Mediators such as interleukins, prostaglandins, nitric oxide and systemic calcium available were studied in this review. Methods: On line searches were accomplished by scrutinizing the database available from PUBMED Central, BVS/BIREME. Web of Science, Science Direct, Periodic Portal from CAPES, as well as The Cochrane Library and PROSPERO were also used. The inclusion criteria were articles that described osteoclastic activity involving the hard dental tissues (cement, dentin and enamel). The search acquired 35 articles and excluded other 30. The articles acquired ranged from 1976 up to 2017. Results: the results showed that the combination of the immunologic mediators researched above will be the determinant factors on the establishment of root resorptions. Conclusions: Prostaglandins, Interleukins as well as the systemic calcium available are some of the most important factors for the establishment of root resorptions. Their final outcome, however, depends directly on the quality of injury inflicted over the group of teeth, or single tooth, involved.

Effects of cystic fibrosis on the oral cavity

Cystic fibrosis is a complex, lethal, multi-system autosomal recessive disease resulting from mutations on chromosome 7 that cause dysfunction of an ion channel located on epithelial surfaces. Pulmonary disease is the leading cause of morbidity and mortality in CF. The specific dental manifestations of the disease may result from the condition itself or from complications of treatment. This study presents the dental problems observed in patients with cystic fibrosis and reported in the literature. Particular attention was paid to dental caries, disturbances in the mineralization of hard dental tissues, gingivitis and changes in the content and properties of saliva.

Vibrational Imaging Techniques for the Characterization of Hard Dental Tissues: From Bench-Top to Chair-Side

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Application of Selected Biomaterials and Stem Cells in the Regeneration of Hard Dental Tissue in Paediatric Dentistry—Based on the Current Literature

Currently, the development of the use of biomaterials and their application in medicine is causing rapid changes in the fields of regenerative dentistry. Each year, new research studies allow for the discovery of additional possibilities of dental tissue restoration. The structure and functions of teeth are complex. They consist of several diverse tissues that need to act together to ensure the tooth’s function and durability. The integrity of a tooth’s enamel, dentin, cementum, and pulp tissue allows for successful mastication. Biomaterials that are needed in dentistry must withstand excessive loading forces, be biocompatible with the hosts’ tissues, and stable in the oral cavity environment. Moreover, each tooth’s tissue, as well as aesthetic qualities in most cases, should closely resemble the natural dental tissues. This is why tissue regeneration in dentistry is such a challenge. This scientific research focuses on paediatric dentistry, its classification of caries, and the use of biomaterials in rebuilding hard dental tissues. There are several methods described in the study, including classical conservative methods such as caries infiltration or stainless-steel crowns. Several clinical cases are present, allowing a reader to better understand the described methods. Although the biomaterials mentioned in this work are artificial, there is currently ongoing research regarding clinical stem cell applications, which have a high potential for becoming one of the most common techniques of lost dental-tissue regeneration in the near future. The current state of stem cell development is mentioned, as well as the various methods of its possible application in dentistry.

COMPUTER TECHNOLOGIES FOR DETERMINING INDEX ASSESSMENT OF THE DESTRUCTION OF DENTAL HARD TISSUES

The aim of the study was to compare the obtained data of hard dental tissues destruction indices with the corresponding indications for the choice of the method of treatment by means of mathematical analysis. Materials & methods. 120 patients aged 20 to 55 were examined and 358 teeth hard tissue defects were identified in them. The data of indices was obtained and compared with the indications for orthopedic treatment according two indices in the same clinical situation. Results. The study showed that the indices had different meanings and different indications for treatment in the same situations. Such discrepancies in indications for treatment indicate the subjective data of one of the indices, which does not take into account the depth of destruction and the volume of the remaining natural tissue of the teeth. Comparison of these indices showed different figures in the same clinical situation, identifying corresponding incorrect indications for the choice of the design of the first investigated index, as well as more accurate data of the proposed index. Conclusion. The index assessment of hard dental tissues destruction serves as the main guideline for the dentist when choosing a method for tooth restoration, and can be calculated using photographs, scans and computer software.

EXPERIMENTAL STUDY OF CHEMICAL COMPOSITION OF DENTAL ENAMEL DURING PROFESSIONAL WHITENING USING HYDROGEN PEROXIDE

Teeth whitening is a way to restore the natural colour of teeth with applying a chemical agent that oxidizes the organic pigments of the hard dental tissues. Teeth whitening has become one of the most frequently requested dental procedures among the population. The public demands whiter, more perfect smiles, and many teeth whitening options have been made in response. To assess the changes occurring in the hard dental tissues, and, in particular, in the enamel, it is necessary to study the chemical structure of the teeth and determine the number of elements in the enamel to predict the whitening procedure outcomes and make adjustments in post-procedural care. The aim of this study was to investigate the changes in the chemical composition of the dental enamel surface after the procedure of professional hygiene and the use of 35% hydrogen peroxide for teeth whitening as the main chemical component of the whitening system. To study the trace element composition of the dental enamel, the tooth surface was segmented into areas for microanalysis. The peculiarity consisted in that the studied areas differed from the right and left sides of the tooth, because the left side in the studied teeth was the control area, and the right side allowed us to compare and contrast the chemical component of enamel in each tooth separately, by comparing the findings. The results obtained have demonstrated that there is a change in the chemical composition of the enamel in the studied teeth. The change in chemical composition indicators significantly affects the change in clinical indicators, and the strength of clinical manifestations will depend on the features of functional and structural resistance of the dental enamel. We can state that changing in the number of elements can lead to increased sensitivity during the rehabilitation period throughout which the chemical composition of the dental enamel restores.

Raman Spectroscopy for Assessment of Hard Dental Tissues in Periodontitis Treatment

The objective of this work was to use Raman spectroscopy to assess hard dental tissues after professional oral hygiene treatment and curettage. Spectral changes were identified, and the discriminant model of the specific changes of intensity of the Raman lines (i.e., of dentin, cementum, and enamel), before and after the dental procedures, was developed. This model showed that 6 weeks after the procedures, the hard dental tissues did not have differences and, thus, provided similar conditions for bio-film and dental plaque formation, tissue repair, and new attachment to the surface of the root.

Erosive Effect of Acidic Beverages On Dental Filling Materials Surface (In Vitro Study)

Erosive tooth wear, that is characterized like irreversible loss of hard dental tissues due to influence of external and internal acids of nonbacterial origin, is one of the most common damage of a tooth surface. Erosive factors also affect the surface of dental reconstruction materials that ideally should be resistant against them. Dental filling materials designed for this purpose must be able to withstand these effects in a comparable or even better way than enamel. In our in vitro study we investigated using the nanoindentation the hardness of currently available dental filling materials (dental composite resin, self curing and dual cures glassionomer cement, dental amalgam) before and after erosive attacks (exposure to Coca Cola for 5 min and 14 days) and consequently compare it with them of human dental enamel. Furtermore we analised the surface topography of the samples before and after acidic exposure by confocal laser scanning microscope. In our experiments the filling materials were affected by the acidic environment only minimally in comparison with hard dental tissues. We confirmed the fact that dental amalgam is still the most mechanically and chemically resistant filling material. Both GIC materials showed the worst resistance against acidic conditions and higher surface roughness even before exposure. We also declared excellent withstanding of resin composite materials against acidic conditions that was even better than natural enamel. Furthermore by CLSM was detected almost unaltered surface of these filling materials. This fact as well as adhesive properties of resin composites allow to assume that this material could be the most suitable material for dental erosion reconstruction.

Blood Parameters and Feline Tooth Resorption: A Retrospective Case Control Study from a Spanish University Hospital

Tooth resorption (TR; progressive destruction of hard dental tissues) varies in prevalence according to population, age, and country (29–66.1%). Our objective was twofold: describing the TR clinical presentation in Northeastern Spain, and studying 34 blood parameters to ascertain potential systemic effects associated with TR. Cases (29; presented from September 2018 to May 2019) and controls (58) were considered. Non-parametric tests were carried out to compare cases and controls for each blood parameter; those showing significant differences were chosen for multiple regression analysis (binomial logistic and hierarchical multiple regressions). In case TR was detected in 130/870 teeth (14.9%), TR stage and type were correlated (p < 0.001). Increasing CREA values (p = 0.034) and decreasing BUN/CREA and ALB/GLOB values were associated with TR presence (p = 0.029 and p = 0.03, respectively). Increasing GLOB was associated with increasing severity of TR (p < 0.01). Type 1 TR (highly related to inflammation and periodontal disease PD) was the most frequently observed type; the association of TR and inflammation biomarkers (ALB/GLOB, GLOB) are explained by this fact. The concomitant presence of PD and TR in old cats would cause TR association with kidney damage biomarkers (CREA, BUN/CREA). When affected by TR, special care in these aspects must be provided to cats.

Dental mask of gastroesophageal reflux disease

In clinical practice, there are patients for whom traditional methods of treatment do not allow getting rid of a dental disease. Dental mask of underlying pathology may be a potential cause of this. The aim of the study was to study the features of the clinical course of dental manifestations of gastroesophageal reflux disease. Methods. The study group included 45 patients aged 20 to 50 years with complaints of pathological changes in the oral cavity that did not stop during the last month. The survey included a survey and clinical examination. The GerdQ questionnaire was used to verify gastrointestinal disorders. Results. It was found that 85% of the surveyed complained of a burning sensation behind the breastbone, the ingress of acidic contents into the oral cavity. 100% of the surveyed presented dental complaints. At the same time, the frequency of dental complaints was significantly higher compared to the frequency of complaints of esophageal symptoms. According to the results of the GerdQ questionnaire, the average score among the subjects was 11.0, which corresponds to the presence of gastroesophageal reflux disease. According to the results of the dental examination, 87% of the examined patients had pathological elements on the oral mucosa, and the pathological elements of aphthous and herpetic stomatitis were found significantly more often in patients with an exacerbation of gastroesophageal reflux disease (p<0.05). Desquamative glossitis was detected in 33% of the examined patients, benign migratory glossitis (“geographical” tongue) in 59% of patients, exfoliative cheilitis (dry form) in 70% of patients, angular cheilitis in 23% of patients. The pathology of hard dental tissues was represented by multiple carious lesions in 75% of patients and non-carious lesions in 53% of patients. Conclusions. Diseases of the oral mucosa and non-carious lesions accompany patients with gastrointestinal tract pathology in the form of gastroesophageal reflux disease.