MULTIPLE MYELOMA: CHALLENGES OF DIFFERENTIAL DIAGNOSIS (CLINICAL CASE)

The objective of our study was to interpret and discuss atypical multiple myeloma case. The article describes the case of clinical observation of a patient K, in which manifestations of chronic kidney disease and circulatory failure prevailed in clinical picture of the disease. The authors recommended an X-ray examination of skull and pelvic bones as a screening method suitable for elderly people with symptoms of chronic renal insufficiency and chronic bone and muscle pain resistant to treatment.

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Mandibular Osteonecrosis Induced by Bisphosphonates in a Carrier of Chronicle Kidney Disease

International Journal of Medical and Surgical Sciences ◽

10.32457/ijmss.2017.005 ◽

2018 ◽

Vol 4 (1) ◽

pp. 1119-1125

Author(s):

Kaohana Da Silva ◽

Greison De Oliveira ◽

Eleonor Garbin-Júnior ◽

Natasha Magro-Érnica ◽

Geraldo Griza ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Multiple Myeloma ◽

Renal Function ◽

Bone Resorption ◽

Kidney Disease ◽

Impaired Renal Function ◽

Clinical Case ◽

Treatment Protocol ◽

Inorganic Pyrophosphate ◽

Jaw Osteonecrosis

The bisphosphonates are synthetic substances of inorganic pyrophosphate that have been the basis of treatment of patients with osteolytic diseases, such as multiple myeloma, malignant hypercalcemia, Paget's disease, or patients with bone metastases. Its main pharmacological effect is inhibition of bone resorption caused by osteoclasts, which have a reduced function. Their adverse effects are infrequent but include pyrexia, impaired renal function, hypocalcemia, and more recently, maxillo-mandibular ostenecrose induced bofosfonatos. In this report we describe a clinical case of jaw osteonecrosis induced by bisphosphonates in patient with chronic kidney disease and the treatment protocol performed.

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Early arthritis as a rheumatological chameleon: a description of a clinical case

Modern Rheumatology Journal ◽

10.14412/1996-7012-2021-5-80-84 ◽

2021 ◽

Vol 15 (5) ◽

pp. 80-84

Author(s):

E. A. Galushko ◽

A. V. Alekseeva ◽

G. V. Serikova ◽

A. S. Semashko

Keyword(s):

Differential Diagnosis ◽

Inflammatory Bowel Diseases ◽

Clinical Picture ◽

Clinical Case ◽

Clinical Observation ◽

Early Arthritis ◽

Differential Diagnostics ◽

Extraintestinal Manifestations ◽

Bowel Diseases ◽

Inflammatory Bowel

The article discusses the difficulties of differential diagnosis of early arthritis and inflammatory bowel diseases with a predominant clinical picture of extraintestinal manifestations, in particular, articular syndrome. The clinical observation demonstrates features of the course of such conditions, a long diagnostic search and a wide list of diseases included in differential diagnostics range.

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Adenoma of the parathyroid gland in a young woman with chronic kidney disease: primary or tertiary hyperparathyroidism?

Terapevticheskii arkhiv ◽

10.26442/00403660.2020.10.000557 ◽

2020 ◽

Vol 92 (10) ◽

pp. 78-82

Author(s):

O. N. Vetchinnikova ◽

E. I. Prokopenko ◽

I. A. Voronkova

Keyword(s):

Chronic Kidney Disease ◽

Differential Diagnosis ◽

Kidney Disease ◽

Parathyroid Adenoma ◽

Parathyroid Gland ◽

Young Woman ◽

Histological Examination ◽

Clinical Observation ◽

Anterior Surface ◽

Tertiary Hyperparathyroidism

Clinical observation of a young woman with chronic kidney disease IV stage and hyperparathyroidism is presented. Ultrasound and99mTc-sestamibi scintigraphy of the anterior surface of the neck visualized a tumor of the left upper parathyroid gland. In a histological examination of distant education was diagnosed a solid parathyroid adenoma. The difficulty of differential diagnosis between primary and secondary/tertiary hyperparathyroidism in chronic kidney disease is discussed.

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Pneumonia as a cause of chronic kidney disease. Clinical case

Medical Science And Education Of Ural ◽

10.36361/1814-8999-2021-22-2-71-74 ◽

2021 ◽

Vol 22 (2) ◽

pp. 71-74

Author(s):

D. A. Elfimov ◽

◽

I. V. Elfimova ◽

M. A. Besedina ◽

◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Kidney Function ◽

Clinical Picture ◽

Clinical Case ◽

Treatment Methods ◽

Kidney Pathology

In recent years, there has been a change in the clinical picture of chronic kidney disease. Often the patient does not notice any of its manifestations. Identifying a diagnosis becomes an “accidental find.” This fact indicates the “insidiousness” of kidney disease. This was probably influenced by changes in treatment methods. Another problem is diseases that previously “did not cause” kidney pathology. It would seem that ordinary pneumonia does not cause significant disorders of kidney function, but recently, more and more often we see extracellular pathology as the main cause of the development of chronic kidney disease.

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Lanthanum-Induced Radiopaque Intestinal Precipitates: A Potential Cause of Intestinal Foreign Bodies

Case Reports in Nephrology ◽

10.1155/2019/1298674 ◽

2019 ◽

Vol 2019 ◽

pp. 1-3 ◽

Cited By ~ 1

Author(s):

Jason Galo ◽

Bianca Madrid ◽

Warren Kupin

Keyword(s):

Chronic Kidney Disease ◽

Differential Diagnosis ◽

Kidney Disease ◽

Phosphate Binder ◽

Foreign Bodies ◽

Medical Resources ◽

Benign Condition ◽

X Ray ◽

Soft Metal ◽

Elemental Form

Lanthanum carbonate is a commonly prescribed oral phosphate binder for use in patients with acute or chronic kidney disease. The elemental form of lanthanum is a soft metal, which will appear radiopaque on a standard X-ray radiograph. This case report illustrates the potential for Lanthanum to masquerade as multiple radiopaque intestinal foreign bodies, leading to the extensive mobilization of medical resources and consultations including serial X-ray monitoring, multiple consultants including acute care and colorectal surgery. Given the few published reports describing this finding in the literature, it is essential to consider Lanthanum precipitates in the differential diagnosis of radiopaque intestinal foreign bodies in patients with chronic kidney disease to avoid unnecessary utilization of medical resources for this predominantly benign condition.

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Clinical Case Studies in Renal Transplantation

Advances in Pulmonary Hypertension ◽

10.21693/1933-088x-12.2.75 ◽

2013 ◽

Vol 12 (2) ◽

pp. 75-75

Keyword(s):

Risk Assessment ◽

Chronic Kidney Disease ◽

Pulmonary Hypertension ◽

Renal Transplantation ◽

Kidney Disease ◽

Case Studies ◽

Clinical Case ◽

Hemodynamic Evaluation ◽

Clinical Case Studies

The case studies below are referred to in the articles “Pulmonary Hypertension in Patients with Chronic Kidney Disease: Noninvasive Strategies for Patient Phenotyping and Risk Assessment” by Amresh Raina, MD, and “Hemodynamic Evaluation of Pulmonary Hypertension in Chronic Kidney Disease” by Ryan Tedford, MD, and Paul Forfia, MD, on the following pages.

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Avaliação da Resiliência em Pacientes com Insuficiência Renal Crônica Submetidos à Hemodiálise / Assessment of Resilience in Patients With Chronic Kidney Disease Undergoing Hemodialysis

REVISTA CIÊNCIAS EM SAÚDE ◽

10.21876/rcsfmit.v6i1.461 ◽

1970 ◽

Vol 6 (1) ◽

pp. 5-13

Author(s):

Renata Izabel dos Santos ◽

Otávia Regina Souza Costa

Keyword(s):

Chronic Kidney Disease ◽

Renal Failure ◽

Health Status ◽

Chronic Renal Failure ◽

Kidney Disease ◽

Renal Insufficiency ◽

Social Economic ◽

Descriptive Study ◽

Psychological Resilience ◽

Resilience Scale

RESUMOObjetivo: Avaliar o nível de resiliência dos portadores de insuficiência renal crônica em tratamento de hemodiálise. Materiais e Métodos: Estudo prospectivo, quantitativo e de abordagem descritiva. A amostra foi constituída por 61 pacientes em tratamento dialítico. Para obtenção dos resultados, foi utilizada a escala de resiliência, desenvolvida por Wagnild e Young (1993) e adaptada por Pesce et al., (2005). Foi aplicado, também, um questionário para caracterização pessoal, familiar, social, econômica e de saúde do grupo. Resultados: Foi constatado que 61% dos pacientes apresentaram tendência à resiliência. O gênero masculino obteve maior pontuação, sugerindo maior tendência à resiliência, bem como os pacientes que são praticantes de uma religião. Conclusão: Os resultados assinalam que os pacientes em tratamento dialítico no hospital apresentam capacidade à resiliência, o que sugere melhor adaptação ao tratamento.Palavras-chave: Avaliação, Resiliência psicológica, Insuficiência renal crônica.ABSTRACTObjective: To evaluate de the level of resilience in patients with chronic renal failure undergoing dialysis. Materials and Methods: Prospective, quantitative and descriptive study. The sample consisted of 61 patients on dialysis. To obtain the results we used Resilience Scale developed by Wagnild and Young (1993) and adapted by Pesce et al., (2005). A questionnaire to characterize personal, familiar, social, economic and health status was applied. Results: It was found that 61% of patients showed trend to resilience. Males had higher scores, suggesting more likelihood to resilience, as well as patients who were practitioners of a religion. Conclusion: The results indicate that the majority of patients on dialysis have capability of resilience, which suggests better adaptation to treatment.Keywords: Evaluation, Psychological resilience, Chronic renal insufficiency.

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Low plasma magnesium concentration and future abdominal aortic calcifications in moderate chronic kidney disease

BMC Nephrology ◽

10.1186/s12882-021-02267-4 ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Anique D. ter Braake ◽

◽

Larissa P. Govers ◽

Mieke J. Peeters ◽

Arjan D. van Zuilen ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Vascular Calcification ◽

Disease Risk ◽

Statistical Significance ◽

Cardiovascular Disease Risk ◽

Magnesium Concentration ◽

X Ray ◽

Abdominal Aortic ◽

Plasma Magnesium

Abstract Background Higher plasma magnesium concentrations are associated with reduced cardiovascular disease risk in chronic kidney disease (CKD) patients. The importance of plasma magnesium concentration for vascular calcification in earlier stages of CKD remains underexplored. This study investigated whether plasma magnesium is a determinant for the presence and severity of vascular calcification in moderate CKD. Methods Retrospective analysis was performed using abdominal aortic calcification (AAC) scores in 280 patients with stage 3 and 4 CKD enrolled in the MASTERPLAN trial. Lateral abdominal X-ray was used to evaluate AAC. Plasma magnesium concentration were measured over time. A zero-inflated Poisson model determined the association between plasma magnesium concentration and AAC. Results 79 out of 280 patients did not have AAC, and in patients with AAC the median calcification score was 3.5 (interquartile range: 0.0–8.6). The mean plasma magnesium concentration was 0.76 ± 0.10 mmol/L at baseline. A 0.1 mmol/L higher plasma magnesium concentration was associated with lower AAC of 0.07 point (95% CI -0.28 – 0.14). A 0.1 mmol/L higher plasma magnesium lowered the odds of detecting any AAC by 30% (OR = 0.63; 95% CI 0.29–1.37). After 1 year and 4 years (at time of X-ray) of follow-up this association was attenuated (OR = 0.93; 95% CI 0.61–1.43 and 0.93; 95% CI 0.60–1.45, respectively). None of these associations reached statistical significance. Conclusions Plasma magnesium concentration at baseline is not associated with the risk for future AAC. Interventions increasing magnesium to avoid vascular calcification may have greatest potential in early CKD stages prior to onset of vascular calcification.

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