scholarly journals THREATENED MISCARRIAGE AND PREGNANCY LOSS: CONTEMPORARY ASPECTS OF THE PROBLEM

2020 ◽  
Vol 73 (5) ◽  
pp. 1021-1027
Author(s):  
Oksana M. Nepyivoda ◽  
Tetiana B. Ryvak
Keyword(s):  
Pregnancy Loss ◽  
System Analysis ◽  
Adverse Outcome ◽  
Negative Influence ◽  
Loss System ◽  
Pregnancy Failure ◽  
Threatened Miscarriage ◽  
Threatened Abortion ◽  
International Experts ◽  
Available Information

The aim is to examine the state of a miscarriage of pregnancy problem and approaches to its solution based on current Ukrainian and international experience; to investigate a relevant set of terms and their interpretations that are tangible to the above-mentioned problem. Materials and methods: modern information sources available for miscarriage and pregnancy loss. System analysis, bibliographic, bibliosemantic, comparative-and-analytical methods were used. Conclusions: A relevant set of terms and their interpretations tangential to the identified problem (n=13) have been researched. It was found that the achievement of rational pharmacotherapy in patients with the threat of miscarriage is complicated mainly by the presence of 4 factors: extragenital pathology, burdened obstetric-gynecological anamnesis, lack of adequate drugs and possibilities of their prescription, especially in the 1st half of pregnancy. Disregarding these factors when prescribing medicines increases the risk of drug-related problems occurrence, prolongation of hospitalization and the adverse outcome of treatment (miscarriage). The results of the analysis of available information flow have shown the existence of terminological ambiguity related to the threat of miscarriage, in particular, there are often the following terms: spontaneous abortion, threatened abortion etc. instead of miscarriage, the threatened miscarriage which are recommended by international experts both in native Ukrainian and foreign researches. Unintended use of inadequate terms, in particular, «pregnancy failure» may form negative influence on women, cause the exaggeration of their condition, induce the feeling of despair, guilt, uncertainty associated with loss of the pregnancy.

Using Ultrasound for Pregnancy Failure in Patients with 1st Trimester Recurrent Pregnancy Loss

2021 ◽  
Vol 84 (1) ◽  
pp. 2361-2365
Author(s):  
Abdelhaseib salah Saad ◽  
Zakaria Fouad Sanad ◽  
Ahmed Hammouda Hossameldin ◽  
Dalia Ibrahim
Keyword(s):  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Pregnancy Failure

scholarly journals COMPARATIVE STUDY OF CLINICAL VERSUS USG IN DIAGNOSIS OF EARLY TRIMESTER BLEEDING PV

2020 ◽  
pp. 60-62
Author(s):  
Narendra Nath Hait ◽  
Brahmarshi Das ◽  
Ratan Chandra Mandal ◽  
Haricharan Roy ◽  
Debarshi Jana
Keyword(s):  
Statistical Analysis ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Common Cause ◽  
Clinical Method ◽  
Medical College ◽  
Threatened Miscarriage ◽  
Obstetrics And Gynaecology ◽  
Threatened Abortion ◽  
The Difference

Background: Threatened abortion is till most common cause of early trimester bleeding PV and can be diagnosed and managed by early USG diagnosis. Materials and methods: This was a prospective observational study. Place of the study was Department of Obstetrics and Gynaecology and Department of Radiodiagnosis, Midnapore Medical College and Hospital from January 2019 to June 2020. Eighteen months. Result: When the clinical method to diagnose threatened miscarriage was compared to the sonographic method, it was evident that sonographic method was reliable than the clinical method and the difference was statistically significant. Conclusion: In case of missed miscarriage and complete miscarriage, although the percentage of discrepancy was 100%, on further statistical analysis, the discrepancy was not statistically significant. And the cause behind this was probably inadequate sampling.

scholarly journals Elevated Circulating IL-1βand TNF-Alpha, and Unaltered IL-6 in First-Trimester Pregnancies Complicated by Threatened Abortion With an Adverse Outcome

2006 ◽  
Vol 2006 ◽  
pp. 1-6 ◽  
Author(s):  
Nicolaos Vitoratos ◽  
Constantinos Papadias ◽  
Emmanuel Economou ◽  
Evangelos Makrakis ◽  
Constantinos Panoulis ◽  
...  
Keyword(s):  
Gestational Age ◽  
Adverse Outcome ◽  
First Trimester ◽  
Wilcoxon Test ◽  
Successful Outcome ◽  
Tnf Alpha ◽  
Obstetric Outcome ◽  
Group A ◽  
Threatened Abortion ◽  
Admission Group

The purpose of the present study was to examine the profile of selected proinflammatory cytokines in maternal serum of first-trimester pregnancies complicated by threatened abortion (TACP) and its relevance to obstetric outcome. Serum levels of Th1-type cytokines interleukin-1β(IL-1β), tumor necrosis factor alpha (TNF-alpha), and Th2-type cytokine interleukin 6 (IL-6) were measured, by ELISA, in 22 women with TACP and adverse outcome at admission (group A) and compared with the corresponding levels of 31 gestational age-matched women with TACP and successful outcome at admission (group B1) and discharge (group B2) and 22 gestational age-matched women with first-trimester uncomplicated pregnancy (group C) who served as controls. Mann-Whitney U or Wilcoxon test was applied as appropriate to compare differences between groups. IL-1βand TNF-alpha were detected with significantly higher levels in group A, compared to all other groups. On the contrary, IL-6 levels were detected with no significant difference among all the other groups studied. It is concluded that in first-trimester TACP with adverse outcome, a distinct immune response, as reflected by elevated maternal IL-1β, TNF-alpha, and unaltered IL-6 levels, is relevant to a negative obstetric outcome.

scholarly journals Perforated uterus

2018 ◽  
Vol 3 (1) ◽  
pp. 46-47
Author(s):  
Justus W Ngatia
Keyword(s):  
Early Detection ◽  
Pregnancy Loss ◽  
Uterine Perforation ◽  
Potential Complication ◽  
Major Health Problem ◽  
Major Health ◽  
Pregnancy Failure ◽  
Dilatation And Curettage ◽  
Early Pregnancy Failure

Early pregnancy failure is a major health problem worldwide which occurs in 15-20% of pregnancies. During evacuation, uterine perforation is a potential complication. Careful post-evacuation follow-up helps in early detection of perforation. Perforation often requires laparotomy or laparoscopy to repair the defect and evaluate for injury to adjacent organs. Our patient had pregnancy loss at 12 weeks and uterine perforation during a dilatation and curettage procedure. She had laparotomy, evacuation through the perforation site and uterine repair with good outcome.

scholarly journals The role of antiphospholipid antibodies on the pathogenesis of habitual pregnancy loss

2002 ◽  
Vol 51 (2) ◽  
pp. 18-22
Author(s):  
O. N. Arzhanova ◽  
T. N. Shliakhtenko ◽  
S. А. Selkov ◽  
T. А. Pluzhnikova ◽  
О. V. Tishkevitch ◽  
...  
Keyword(s):  
Blood Plasma ◽  
Perinatal Mortality ◽  
Antiphospholipid Antibodies ◽  
Preterm Labor ◽  
Pregnancy Loss ◽  
Control Group ◽  
Threatened Abortion ◽  
Immunofluorescent Analysis ◽  
Present Pregnancy

Clinical and anamnesis analysis as well as analysis of the course and outcome of the present pregnancy was performed on 595 patients with complicated obstetrical and gynecological history (COGH) habitual pregnancy loss, infertility, genital chronic processes. Control groupconsisted of 5O healthy women. Immunofluorescent analysis was used to reved antiphospholipid antibodies on blood plasma. Antiphospholipid antibodies were found in 42% of COGH women. No antiphospholipid antibodies were seen in the control group. In all patients of the studied groupthe course of pregnancy was accompanied with signs of threatened abortion, gestosis. 29% (p O, O1) patients had preterm labor and spontaneous abortion occurred in 18% (p O, O1) of cases. Perinatal mortality was 9, 8%4, 16.

Pituitary incidentalomas: the clinical picture, diagnostics, differential diagnostics, and methods of treatment

2015 ◽  
Vol 61 (3) ◽  
pp. 57-68 ◽  
Author(s):  
I I Dedov ◽  
G A Melnichenko ◽  
L K Dzeranova ◽  
E A Pigarova ◽  
L Ya Rozhinskaya ◽  
...  
Keyword(s):  
Clinical Signs ◽  
Signs And Symptoms ◽  
Long Term Results ◽  
Differential Diagnostics ◽  
Diagnostic Study ◽  
Wide Circle ◽  
Clinical Signs And Symptoms ◽  
Set Up ◽  
International Experts ◽  
Available Information

Incidentalomas are the most common neoplasms in the hypothalamic-pituitary region. Diagnostics, treatment strategy, and indications for the surgical intervention on the patients with these tumours pose a serious challenge for a wide circle of specialists. The diagnostic problems arise from the absence of the specific clinical signs and symptoms as well as the reliable biochemical markers of the disease. The modern laboratory methods do not allow to reveal the pathological hormonal secretion during the diagnostic study, predisposition of the neoplasm to the invasive and infiltrative growth, and signs of its «aggressiveness». This considerably complicates the choice of the optimal surgical strategy and the evaluation of the long-term results of the treatment. Bearing in mind the importance of the problem under consideration, the working group was set up for the development of federal recommendations on the treatment of pituitary incidentalomas based on the principles of evidence-based medicine. The experience accumulated by the domestic and international experts was summarized in the federal clinical guidelines on pituitary incidentalomas containing the available information about these neoplasms.

scholarly journals International workshop on safety assessment of consumer goods coming from recovered materials in a global scale perspective

2012 ◽  
Vol 2 (1) ◽  
pp. 20-26
Author(s):  
Bernd Bilitewski ◽  
Damià Barceló ◽  
Rosa Mari Darbra ◽  
Ester V.d. Voet ◽  
Mohammed Belhaj ◽  
...  
Keyword(s):  
International Workshop ◽  
Global Scale ◽  
Global Network ◽  
Management Options ◽  
Essential Chemical ◽  
Risk Reduction Measures ◽  
International Experts ◽  
Available Information ◽  
Chemical Testing ◽  
The Eu

Chemicals and additives in products being produced and marketed globally, this makes an international harmonised assessment and management essential. Chemical testing, research on risks, impacts and management options are carried out throughout the globe but quite fractionated to certain areas and sectors and much too often with little linkages between the different scientific communities. The coordination action (CA) "RISKCYCLE" is aimed to establish and co-ordinate a global network of European and international experts and stakeholders to define together future needs of R+D contributions for innovations in the risk-based management of chemicals and products in a circular economy of global scale leading to alternative strategies to animal tests and reduced health hazards. The partners joining this action seek to explore the synergies of the research carried out within different programmes and countries of the EU, in Asia and overseas to facilitate the intensified communication with researchers, institutions and industries about the risks of hazardous chemicals and additives in products and risk reduction measures and to improve the dispersion of available information. The RISKCYCLE network will closely collaborate with related projects, EU and international bodies and authorities such as for example the Organisation for Economic Co-operation and Development (OECD), the European Chemical Industry Council (CEFIC) and the Scientific Committee on Health and Environmental Risks in Europe. Mục đích chính của RISKCYCLE là xác đinhcác nghiện cứu và sự phát triển trong tương lai cấn thiết để thành lập một phương pháp đánh giá dựa trện rủi ro cho các hoá chất và các sản phấm. Phương pháp này sẽ giúp giảm bớt các thủ nghiệm trện động vật, đổng thời đảm bảo sự phát triển các hóa chất mới và một mô hình quản lý sản phấm để giảm thiểu rủi ro đối với sức khởe và môi trường. để đạt được mục tiệu này, trước hết cấn thu thập và đánh giá thông tin hiện có về các hoá chất và đặc biệt là các chất phụ gia được sủ dụng trong sản phấm công nghiệp và tiệu dùng. Nhiều hợp chất độc hại tiềm tàng được giao dich mua bán trện toàn thế giới như là chất phụ gia trong các sản phấm khác nhau. RISKCYCLE sẽ tập trung vào tác động và hậu quả của các chất phụ gia trong sáu lĩnh vực: dệt may, điện tủ, nhựa, da, giấy và dấu mớ bôi trơn. Trong ngành công nghiệp dệt may việc sủ dụng các chất phụ gia sẽ được nghiện cứu, trong khi ở ngành điện tủ và công nghiệp dệt may, việc sủ dụng các chất chống cháy, đặc biệt là chất chống cháy chứa brôm như PBDEs và HBCD, sẽ được phân tích. Trong công nghiệp da, kim loại nặng như crom sẽ được quan tâm. Việc sủ dụng chất diệt côn trùng trong ngành công nghiệp giấy cũng sẽ là một mối quan tâm chính của các hoạt động phối hợp.

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