scholarly journals Genome sequence of Vibrio sp. OULL4 isolated from shellfish

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Vengadesh Letchumanan ◽  
Wen-Si Tan ◽  
Wai-Fong Yin ◽  
Kok-Gan Chan
Keyword(s):  
Vibrio Cholerae ◽  
Genome Sequence ◽  
Vibrio Parahaemolyticus ◽  
Vibrio Vulnificus ◽  
Diverse Group ◽  
Seafood Consumption ◽  
Negative Bacterium ◽  
Antibiotic Resistant ◽  
Gram Negative ◽  
Resistant Strains

The members of Vibrionaceae family are Gram-negative bacterium are ubiquitous in marine and estuarine environments. This diverse group of bacteria include many pathogenic strains that potentially cause infection to humanand aquaculture animals. Vibrio cholerae, Vibrio parahaemolyticus and Vibrio vulnificus are among the few recognized as a major, worldwide cause gastroenteritis, particularly in countries where seafood consumption is high. The control of these vibrios has been a hurdle due to the rising numbers of antibiotic resistant strains in the environments. We report the genome sequence of Vibrio sp. OULL4 isolated from shellfish. The availability of this genome sequence will facilitate the study of its antimicrobial traits, as well as add our knowledge of Vibrio sp. diversity and evolution.

scholarly journals Screening of an FDA-Approved Library for Novel Drugs against Y. pestis

Antibiotics ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 40
Author(s):  
David Gur ◽  
Theodor Chitlaru ◽  
Emanuelle Mamroud ◽  
Ayelet Zauberman
Keyword(s):  
Drug Repurposing ◽  
Mortality Rates ◽  
Systematic Screening ◽  
Antibiotic Resistant ◽  
Gram Negative ◽  
Therapy Initiation ◽  
Novel Drugs ◽  
Resistant Strains ◽  
Approved Drugs ◽  
Fda Approved Drugs

Yersinia pestis is a Gram-negative pathogen that causes plague, a devastating disease that kills millions worldwide. Although plague is efficiently treatable by recommended antibiotics, the time of antibiotic therapy initiation is critical, as high mortality rates have been observed if treatment is delayed for longer than 24 h after symptom onset. To overcome the emergence of antibiotic resistant strains, we attempted a systematic screening of Food and Drug Administration (FDA)-approved drugs to identify alternative compounds which may possess antibacterial activity against Y. pestis. Here, we describe a drug-repurposing approach, which led to the identification of two antibiotic-like activities of the anticancer drugs bleomycin sulfate and streptozocin that have the potential for designing novel antiplague therapy approaches. The inhibitory characteristics of these two drugs were further addressed as well as their efficiency in affecting the growth of Y. pestis strains resistant to doxycycline and ciprofloxacin, antibiotics recommended for plague treatment.

scholarly journals Draft Genome Sequence of Pantoea sp. Strain A4, a Rafflesia-Associated Bacterium That ProducesN-Acylhomoserine Lactones as Quorum-Sensing Molecules

2012 ◽  
Vol 194 (23) ◽  
pp. 6610-6610 ◽  
Author(s):  
Kar-Wai Hong ◽  
Han Ming Gan ◽  
Siew-Moon Low ◽  
Patrick Kok Yuen Lee ◽  
Yee-Meng Chong ◽  
...  
Keyword(s):  
Quorum Sensing ◽  
Genome Sequence ◽  
Draft Genome ◽  
Draft Genome Sequence ◽  
Negative Bacterium ◽  
Gram Negative ◽  
Content Type ◽  
First Time

ABSTRACTPantoeasp. strain A4 is a Gram-negative bacterium isolated from theRafflesiaflower. We present here, for the first time, the genome sequence ofRafflesia-associatedPantoeasp. strain A4, which exhibited quorum-sensing activity.

scholarly journals Antibiogram signatures of non-cholera causing Vibrio species recovered from environmental niches in Eastern Cape, South Africa.

2021 ◽  
Author(s):  
Oluwakemi Victoria Ayodele ◽  
Anthony Ifeanyi Okoh
Keyword(s):  
Minimum Inhibitory Concentration ◽  
Nalidixic Acid ◽  
Vibrio Parahaemolyticus ◽  
Inhibitory Concentration ◽  
Vibrio Vulnificus ◽  
Diffusion Method ◽  
Morbidity Rate ◽  
Antibiotic Resistant ◽  
Mortality And Morbidity ◽  
Vibrio Fluvialis

Abstract Background: The use of antibiotics globally has helped reduce mortality and morbidity rate due to its ability to effectively treat bacterial infections in both humans and animals. However, the menace of antimicrobial resistance has become a challenge to public health due to its increased mortality and morbidity rate. This study determined the antibiogram pattern of non-cholera causing Vibrio species against a panel of 11 antibiotics that are wildly used for treatment. Multiple antibiotic resistance phenotype, multiple antibiotic resistant indices and minimum inhibitory concentration (MIC) of test antibiotics were also determined.Results: Polymerase chain reaction (PCR) was used to confirm 100 isolates of Vibrio parahaemolyticus, 82 and 46 isolates of Vibrio vulnificus and Vibrio fluvialis respectively, collected from the culture collections of the Applied and Environmental Microbiology Research Group (AEMREG), University of Fort Hare. Thereafter, disc diffusion method was used to determine the antibiogram pattern of target non-cholera causing Vibrio species against a panel of 11 antibiotics that are of clinical importance. The highest rate of Vibrio parahaemolyticus resistance was observed against tetracycline (22 %) and nalidixic acid (16 %). Vibrio fluvialis also displayed highest rate of resistance against tetracycline (28 %) and nalidixic acid (28 %), while Vibrio vulnificus isolates exhibited highest rate resistance against imipenem (40 %) and tetracycline (22 %). A total of 38 MARP patterns were observed and the MAR indices ranged between 0.3 and 0.8. Against the resistant Vibrio parahaemolyticus and Vibrio fluvialis isolates, minimum inhibitory concentration ranged from 16 µg/ml to 2048 µg/ml for both tetracycline and nalidixic acid, while against Vibrio vulnificus isolates, minimum inhibitory concentration ranged from 8 µg/ml to 256 µg/ml for both imipenem and nalidixic acid. Conclusions: Results obtained from this study is an indication that antibiotic resistant bacteria that could pose as threat to health of humans and animals are present in the environment.

scholarly journals Draft Genome Sequence of Cloacibacterium normanense NRS-1 Isolated from Municipal Wastewater

2016 ◽  
Vol 4 (6) ◽  
Author(s):  
Nicole R. Gay ◽  
Elizabeth Fleming ◽  
Julia Oh
Keyword(s):  
Genome Sequence ◽  
Municipal Wastewater ◽  
Draft Genome ◽  
Phosphate Removal ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Negative Bacterium ◽  
Apparent Absence ◽  
Gram Negative ◽  
Human Stool

Cloacibacterium normanense is a Gram-negative bacterium recovered from untreated human wastewater. Given its high abundance in wastewater and its apparent absence in human stool, it may contribute to biological phosphate removal. Here, we perform a whole-genome sequence of C. normanense NRS-1(T) and examine particular features of this draft genome.

scholarly journals Complete Genome Sequence of Proteus mirabilis Phage Mydo

2019 ◽  
Vol 8 (47) ◽  
Author(s):  
Benjamin T. Jones ◽  
Lauren Lessor ◽  
Chandler O’Leary ◽  
Jason Gill ◽  
Mei Liu
Keyword(s):  
Escherichia Coli ◽  
Genome Sequence ◽  
Proteus Mirabilis ◽  
Nosocomial Infections ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Antibiotic Resistant ◽  
Content Type ◽  
Resistant Strains

Proteus mirabilis is a pathogen that has been linked to nosocomial infections. Studies on phages infecting P. mirabilis may provide therapeutics for infections caused by antibiotic-resistant strains of this pathogen. Here, we announce the complete genome sequence of a P. mirabilis myophage, Mydo, which is distantly related to Escherichia coli phage rv5.

scholarly journals Complete Genome Sequence of Pseudomonas sp. Strain phDV1, an Isolate Capable of Efficient Degradation of Aromatic Hydrocarbons

2019 ◽  
Vol 8 (2) ◽  
Author(s):  
Hao Xie ◽  
Giannis Valsamidis ◽  
Eirini Mathioudaki ◽  
Georgios Tsiotis
Keyword(s):  
Genome Sequence ◽  
Aromatic Hydrocarbons ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Pseudomonas Sp ◽  
Negative Bacterium ◽  
Gram Negative ◽  
Content Type

Pseudomonas sp. strain phDV1 is a Gram-negative bacterium capable of degrading aromatic hydrocarbons. Here, we present the complete genome sequence of this strain, which consists of 4,727,682 bp, with a 62.3% G+C content and 4,574 genes.

scholarly journals Light-scattering sensor for real-time identification of Vibrio parahaemolyticus , Vibrio vulnificus and Vibrio cholerae colonies on solid agar plate

2012 ◽  
Vol 5 (5) ◽  
pp. 607-620 ◽  
Author(s):  
Karleigh Huff ◽  
Amornrat Aroonnual ◽  
Amy E. Fleishman Littlejohn ◽  
Bartek Rajwa ◽  
Euiwon Bae ◽  
...  
Keyword(s):  
Light Scattering ◽  
Vibrio Cholerae ◽  
Real Time ◽  
Vibrio Parahaemolyticus ◽  
Vibrio Vulnificus ◽  
Agar Plate ◽  
Solid Agar ◽  
Real Time Identification

scholarly journals Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate

2020 ◽  
Vol 9 (3) ◽  
Author(s):  
Travis J. Kochan ◽  
Egon A. Ozer ◽  
Nathan B. Pincus ◽  
Margaret A. Fitzpatrick ◽  
Alan R. Hauser
Keyword(s):  
Klebsiella Pneumoniae ◽  
Genome Sequence ◽  
Nosocomial Infections ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Multidrug Resistant ◽  
Negative Bacterium ◽  
Gram Negative ◽  
Content Type ◽  
Rapid Dissemination

Klebsiella pneumoniae is a Gram-negative bacterium that is a major cause of nosocomial infections worldwide. Here, we present the complete genome sequence of TK421, a clinical bacteremia isolate containing a hypervirulence plasmid carrying tra-associated conjugation machinery genes. Emergence of conjugative hypervirulence plasmids could portend rapid dissemination of hypervirulence among multidrug-resistant K. pneumoniae strains.

scholarly journals Complete Genome Sequence of Klebsiella pneumoniae Myophage May

2019 ◽  
Vol 8 (19) ◽  
Author(s):  
Katherine T. Nguyen ◽  
Rachele Bonasera ◽  
Garret Benson ◽  
Adriana C. Hernandez-Morales ◽  
Jason J. Gill ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Multidrug Resistant ◽  
Antibiotic Resistant ◽  
Content Type ◽  
Resistant Strains

May is a newly isolated myophage that infects multidrug-resistant strains of Klebsiella pneumoniae, a pathogen that is associated with antibiotic-resistant infections in humans. The genome of May has been shown to be similar to that of phage Vi01.

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