Prevalence of Cardiovascular Risk Factors Among Patients with Acute Myocardial Infarction and New Left Bundle Branch Block in North East Romania

2018 ◽  
Vol 69 (6) ◽  
pp. 1554-1557
Author(s):  
Larisa Anghel ◽  
Catalina Arsenescu Georgescu
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Cardiovascular Disease ◽  
Acute Myocardial Infarction ◽  
Cardiovascular Risk ◽  
Left Bundle Branch Block ◽  
New Left ◽  
Bundle Branch Block ◽  
North East ◽  
History Of

The prevalence of coronary artery disease, a major contributor to cardiovascular disease, is related to the increasing prevalence of modifiable risk factors.The aim of our study was to determine the risk factors for acute myocardial infarction among patients from North East Romania.We evaluated patients with acute myocardial infarction with or without left bundle-branch block, hospitalized in Georgescu Institute of Cardiovascular Disease Iasi for three years. The results of our study show that patients with acute myocardial infarction and new left bundle branch block have a more recent history of hypertension, dyslipidemia and smoker status compared to patients without left bundle branch block. Nearly two thirds of patients included in the study (65.47%) had an elevated cholesterol level, with a high prevalence of dyslipidemia in patients with myocardial infarction and new left bundle branch block. More than two-thirds of patients with new left bundle branch block had a history of arterial hypertension (69.04% vs. 50.0%, p = 0.354), especially grade 2 hypertension, with a slight predominance in those with new left bundle branch block, but without statistically significant differences between the two groups (45.23% vs. 30.95%, p = 0.358). Early identification of modifiable risk factors is vital to set the strategy for prevention and special attention must be paid to smoking. An adequate control of cardiovascular risk factors would result in a significant reduction of coronary events in patients from the North East part of Romania.

scholarly journals NEW OR PRESUMED NEW LEFT BUNDLE BRANCH BLOCK IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION: FINDINGS FROM ACTION REGISTRY-GWTG

2010 ◽  
Vol 55 (10) ◽  
pp. A107.E1000 ◽  
Author(s):  
Khung Keong Yeo ◽  
Shuang Li ◽  
Tracy Y. Wang ◽  
Deepak L. Bhatt ◽  
Jorge Saucedo ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Left Bundle Branch Block ◽  
New Left ◽  
Bundle Branch Block

Prevalence of acute myocardial infarction in patients with presumably new left bundle-branch block

2012 ◽  
Vol 45 (4) ◽  
pp. 361-367 ◽  
Author(s):  
Nilay Mehta ◽  
Henry D. Huang ◽  
Salman Bandeali ◽  
James M. Wilson ◽  
Yochai Birnbaum
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Left Bundle Branch Block ◽  
New Left ◽  
Bundle Branch Block

scholarly journals Risk factors for non-fatal myocardial infarction in young South Asian adults

Heart ◽  
2004 ◽  
Vol 90 (3) ◽  
pp. 259-263 ◽  
Author(s):  
J Ismail ◽  
T H Jafar ◽  
F H Jafary ◽  
F White ◽  
A M Faruqui ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Cardiovascular Disease ◽  
Acute Myocardial Infarction ◽  
Low Income ◽  
South Asians ◽  
Fasting Blood Glucose ◽  
Acute Myocardial Infarct ◽  
Parental Consanguinity ◽  
History Of

Objective: To determine the risk factors for premature myocardial infarction among young South Asians.Design and setting: Case–control study in a hospital admitting unselected patients with non-fatal acute myocardial infarction.Methods and subjects: Risk factor assessment was done in 193 subjects aged 15–45 years with a first acute myocardial infarct, and in 193 age, sex, and neighbourhood matched population based controls.Results: The mean (SD) age of the subjects was 39 (4.9) years and 326 (84.5%) were male. Current smoking (odds ratio (OR) 3.82, 95% confidence interval (CI) 1.47 to 9.94), use of ghee (hydrogenated vegetable oil) in cooking (OR 3.91, 95% CI 1.52 to 10.03), raised fasting blood glucose (OR 3.32, 95% CI 1.21 to 8.62), raised serum cholesterol (OR 1.67, 95% CI 1.14 to 2.45 for each 1.0 mmol/l increase), low income (OR 5.05, 95% CI 1.71 to 14.96), paternal history of cardiovascular disease (OR 4.84, 95% CI 1.42 to 16.53), and parental consanguinity (OR 3.80, 95% CI 1.13 to 1.75) were all independent risk factors for acute myocardial infarction in young adults. Formal education versus no education had an independently protective effect on acute myocardial infarction (OR 0.04, 95% CI 0.01 to 0.35).Conclusions: Tobacco use, ghee intake, raised fasting glucose, high cholesterol, paternal history of cardiovascular disease, low income, and low level of education are associated with premature acute myocardial infarction in South Asians. The association of parental consanguinity with acute myocardial infarction is reported for the first time and deserves further study.

scholarly journals PATIENTS WITH NEW OR PRESUMABLY NEW LEFT BUNDLE BRANCH BLOCK HAVE A LOW RATE OF ACUTE MYOCARDIAL INFARCTION

2010 ◽  
Vol 55 (10) ◽  
pp. A107.E1002
Author(s):  
Michael C. Kontos ◽  
Vinh Q. Chau ◽  
Charlotte S. Roberts ◽  
Joseph P. Ornato ◽  
George W. Vetrovec
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Left Bundle Branch Block ◽  
New Left ◽  
Bundle Branch Block ◽  
Low Rate

The prognostic value of a new left bundle branch block in patients with acute myocardial infarction: A systematic review and meta-analysis

Heart & Lung ◽  
2017 ◽  
Vol 46 (2) ◽  
pp. 85-91 ◽  
Author(s):  
Belal Al Rajoub ◽  
Samar Noureddine ◽  
Samer El Chami ◽  
Mohamad Hussein Haidar ◽  
Bachir Itani ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Systematic Review ◽  
Acute Myocardial Infarction ◽  
Left Bundle Branch Block ◽  
Prognostic Value ◽  
Meta Analysis ◽  
New Left ◽  
Bundle Branch Block

CARDIOVASCULAR RISK FACTORS PECULIARITIES IN MEN UNDER 60 YEARS OLD WITH MYOCARDIAL INFARCTION AND CHRONIC INFLAMMATORY LUNG DISEASES

2020 ◽  
pp. 21-25
Author(s):  
Tupitsyn V.V. ◽  
Bataev Kh.M. ◽  
Men’shikova A.N. ◽  
Godina Z.N.
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Digestive System ◽  
Control Group ◽  
Study Group ◽  
Type I ◽  
Internal Organs ◽  
History Of

Relevance. Information about the cardiovascular diseases risk factors (CVD RF) for in men with chronic lung inflam-matory pathology (CLID) is contradictory and requires clarification. Aim. To evaluate the peculiarities of CVD RF in men under 60 years of age with CLID in myocardial infarction (MI) to improve prevention. Material and methods. The study included men aged 19-60 years old with type I myocardial infarction. Patients are divided into two age-comparable groups: I - the study group, with CLID - 142 patients; II - control, without it - 424 patients. A comparative analysis of the frequency of observation of the main and additional cardiovascular risk fac-tors in groups was performed. Results. In patients of the study group, more often than in the control group we observed: hereditary burden of is-chemic heart disease (40.8 and 31.6%, respectively; p = 0.0461) and arterial hypertension (54.2 and 44.6%; p = 0.0461), frequent colds (24.6 and 12.0%; p = 0.0003), a history of extrasystoles (19.7 and 12.7%; p = 0.04); chronic foci of infections of internal organs (75.4 and 29.5%; p˂0.0001), non-ulcer lesions of the digestive system (26.1 and 14.6%; p = 0.007), smoking (95.1 and 66.3%; p˂0.0001), MI in winter (40.8 and 25.9%; p = 0.006). Less commonly were observed: oral cavity infections (9.2 and 23.6%; p˂0.0001); hypodynamia (74.5 and 82.5%; p = 0.0358), over-weight (44.4 and 55.2%; p = 0.0136), a subjective relationship between the worsening of the course of coronary heart disease and the season of the year (43.7 and 55.2%; p = 0.0173) and MI - in the autumn (14.1 and 21.9%; p = 0.006) period. Conclusions. The structure of CVD RF in men under 60 years of age with CLID with MI is characterized by the pre-dominance of smoking, non-ulcer pathology of the digestive system, frequent pro-student diseases, meteorological dependence, a history of cardiac arrhythmias and foci of internal organ infections. It is advisable to use the listed factors when planning preventive measures in such patients.

scholarly journals OP0234 RISK OF ACUTE MYOCARDIAL INFARCTION AMONG NEW USERS OF CHONDROITIN SULPHATE: A NESTED CASE-CONTROL STUDY

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 144.1-144
Author(s):  
R. Mazzucchelli ◽  
S. Rodriguez-Martin ◽  
A. García-Vadillo ◽  
M. Gil ◽  
A. Rodríguez-Miguel ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Cardiovascular Disease ◽  
Acute Myocardial Infarction ◽  
Cardiovascular Risk ◽  
Case Control Study ◽  
Chondroitin Sulphate ◽  
Case Control ◽  
Nested Case Control ◽  
Incident Cases ◽  
Control Study

Background:There is some evidence from epidemiological studies suggesting that CS and glucosamine could play a role in cardiovascular disease (CVD) prevention (1-4).Studies to date have included prevalent users, therefore a bias that overestimates protection cannot be excluded.Objectives:To test the hypothesis that chondroitin sulphate (CS) or glucosamine reduce the risk of acute myocardial infarction (AMI).Methods:Case-control study nested in a primary cohort composed of patients aged 40 to 99 years, with at least one year of follow-up in the BIFAP database during the 2002-2015 study period. From this cohort of patients, we identified incident cases of AMI and randomly selected five controls per case, matched by exact age, gender, and index date. Adjusted odds ratios (AOR) and their corresponding 95% confidence interval (CI)) were calculated through a conditional logistic regression. Only new users of CS or glucosamine were considered.Results:A total of 23,585 incident cases of AMI and 117,405 controls were included. The mean age was 67.0 (SD 13.4) years and 71.75% were male, in both groups. 558 (2.37%) cases and 3,082 (2.62%) controls used or had used CS. The current use of CS was associated with a lower risk of AMI (AOR 0.57; 95%CI: 0.46–0.72) and disappeared after discontinuation (recent and past users). The reduced risk among current users was observed in both short-term (<365 days AOR 0.58; 95%CI: 0.45-0.75) and long-term users (>364 days AOR 0.56; 95%CI 0.36-0.87), in both sexes (men, AOR=0.52; 95%CI:0.38-0.70; women, AOR=0.65; 95%CI: 0.46-0.91), in individuals over or under 70 years of age (AOR=0.54; 95%CI:0.38-0.77, and AOR=0.61; 95%CI:0.45-0.82, respectively) and in individuals at intermediate (AOR=0.65; 95%CI:0.48-0.91) and high cardiovascular risk (AOR=0.48;95%CI:0.27-0.83), but not in those at low risk (AOR=1.11; 95%CI:0.48-2.56). In contrast, the current use of glucosamine was not associated with either increased or decreased risk of AMI (AOR= 0.86; CI95% 0.66-1.08)Conclusion:Our results support a cardioprotective effect of CS, while no effect was observed with glucosamine. The highest protection was found among subgroups at higher cardiovascular risk.References:[1]Ma H, Li X, Sun D, Zhou T, Ley SH, Gustat J, et al. Association of habitual glucosamine use with risk of cardiovascular disease: prospective study in UK Biobank. BMJ. 2019;365(Journal Article):l1628.[2]de Abajo FJ, Gil MJ, Garcia Poza P, Bryant V, Oliva B, Timoner J, et al. Risk of nonfatal acute myocardial infarction associated with non-steroidal antiinflammatory drugs, non-narcotic analgesics and other drugs used in osteoarthritis: a nested case-control study. PharmacoepidemiolDrug Saf. 2014;23(11):1128–38.[3]Li Z-H, Gao X, Chung VC, Zhong W-F, Fu Q, Lv Y-B, et al. Associations of regular glucosamine use with all-cause and cause-specific mortality: a large prospective cohort study. Ann Rheum Dis. 2020 Apr 6;annrheumdis-2020-217176.[4]King DE, Xiang J. Glucosamine/Chondroitin and Mortality in a US NHANES Cohort. J Am Board Fam Med. 2020 Dec;33(6):842–7.Disclosure of Interests:Ramón Mazzucchelli Speakers bureau: UCB, Lilly, Grant/research support from: Pfizer, Roche, Amgen, Sara Rodriguez-Martin: None declared, Alberto García-Vadillo: None declared, Miguel Gil: None declared, Antonio Rodríguez-Miguel: None declared, Diana Barreira-Hernández: None declared, Alberto García-Lledó: None declared, Francisco de Abajo: None declared

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