STUDI GAMBARAN HASIL PEMERIKSAAN APUSAN DARAH TEPI PADA IBU HAMIL DI LABORATORIUM RSUD H.A.SULTHAN DAENG RADJA KABUPATEN BULUKUMBA

2018 ◽  
Vol 3 (2) ◽  
pp. 13-26
Author(s):  
Rahmat Aryandi ◽  
Subakhir Salnus
Keyword(s):  
Platelet Count ◽  
Pregnant Women ◽  
Blood Smear ◽  
Leukocyte Count ◽  
Marked Change ◽  
Peripheral Blood Smear ◽  
Morphological Examination ◽  
Laboratory Observation ◽  
Hematologic Disorder ◽  
Normal Platelet

During pregnancy, there will be a marked change in anatomy, physiology and biochemistry since the onset of pregnancy and often lackof nutrient intake. Hematologic disorder is often found in pregnant women because it causes pregnant women more susceptible to disturbances in blood circulation, The purpose of this study to determine the description of blood smear results in pregnant women in the laboratory RSUD H.A.Sulthan Daeng Radja District. This research is descriptive with laboratory observation approach. The sample used in this study were 30 samples of pregnant women who checked themselves in the Laboratory of RSUDH.A.Sulthan Daeng Radka Bulukumba District. The result of this research showed the result of peripheral blood smear on the morphology of erythrocytes using 30 samples of pregnant women showed 14 samples (46,66%) normocytic normochrom and the remaining 16 samples were morphological variation (53,33%), on morphological examination and platelet count with using 30 samples of pregnant women showed each 29 samples had morphology and normal platelet counts with respectively 96.66% percentage and platelet aggregation and decreased platelet count (thrombocytopenia) with each persentase 3.33%. At leukocyte morphology examination using 30 samples of pregnant women showed 29 samples had normal morphology with 96,66% percentage and one sample with hypersegmentation with percentage 3,33%. normal leukocyte count at 9 samples with percentage 30% and leukocyte count increased at 21 samples with percentage 70%.

PENENTUAN KRITERIA PENILAIAN KESAN JUMLAH LEUKOSIT PADA PEMERIKSAAN APUSAN DARAH TEPI

2018 ◽  
Vol 3 (2) ◽  
pp. 27-34
Author(s):  
Aan Yulianingsih Anwar ◽  
Nurhamsiah
Keyword(s):  
Platelet Count ◽  
Human Body ◽  
Peripheral Blood ◽  
Blood Smear ◽  
Peripheral Blood Smear ◽  
Blood Components ◽  
Laboratory Observation ◽  
Normal Platelet ◽  
Zone Ii ◽  
The Difference

Platelets are one of the blood components present in the human body, which play an important role in hemostasis. A good macroscopic and microscopic peripheral blood smear is essential in assessing success in the manufacture of peripheral blood smear preparations. This research was conducted on March, 9thto May, 31st2018 at Hematology Laboratory of Health Polytechnic of Makassar majoring in Health Analyst. The purpose of this study to determine the number of thrombocytes view ability and declared the impression of sufficient quantities. The type of research used in this study is laboratory observation that aims to determine the assessment criteria impression of the number of platelets in the peripheral blood smear. The results showed that the number of platelets in zone I obtained results the impression of the number of platelets 5-9 stated the amount of normal platelet impression, zone II obtained the result total number of platelets impression 6-10 stated the amount of normal platelet impression, and the impression of the results obtained III zone number of platelets 7-11 stated the number of the impression of normal platelets. Therefore, advisable to the laboratory to calculate the platelet count using the peripheral blood smear method by counting at zone II and in subsequent studies it is better to examine the difference in platelet counts in each zone in the peripheral blood smear.

scholarly journals A Rare Cause of Thrombocytopenia: Pseudothrombocytopenia

2020 ◽  
Vol 9 (3) ◽  
pp. 184-186
Author(s):  
Hatice Tuba Akbayram ◽  
Esra Pekpak
Keyword(s):  
Platelet Count ◽  
Blood Count ◽  
Blood Smear ◽  
Peripheral Blood Smear ◽  
Blood Platelet ◽  
Normal Platelet ◽  
Blood Platelet Disorders ◽  
Incorrect Diagnosis ◽  
Low Platelet Count

Pseudothrombocytopenia is caused by in vitro platelet clumping in anticoagulated blood. Electronic blood count shows a low platelet count in subjects with normal platelet levels. The situation may be mistaken with true thrombocytopenia and may lead to incorrect diagnosis and treatment. Microscopic examination of the peripheral blood smear is of key importance to confirm the diagnosis. The aim of this case report was to draw attention to pseudotyhrombocytopenia, which is one of the possible causes of thrombocytopenia. Keywords: thrombocytes, thrombocytopenia, blood platelet disorders

PENENTUAN KRITERIA PENILAIAN KESAN JUMLAH LEUKOSIT PADA PEMERIKSAAN APUSAN DARAH TEPI

2018 ◽  
Vol 3 (2) ◽  
pp. 52-61
Author(s):  
Dzikra Arwie ◽  
Islawati
Keyword(s):  
Data Analysis ◽  
Statistical Analysis ◽  
Blood Cells ◽  
Blood Smear ◽  
White Blood Cells ◽  
Peripheral Blood Smear ◽  
Field Of View ◽  
Laboratory Observation ◽  
Number Of Cells

Leukocytes or white blood cells have a characteristic characteristic of different cells. Determination of the impression of the number of leukocytes is determined in the number of cells in the field of view. While the number of viewable field cells expressed is still quite varied. The purpose of this study was to determine the number of leukocytes in the field of view and expressed the impression of a sufficient amount. This research was conducted at the Laboratory of Health Analyst Department Panrita Husada Bulukumba on 9 April 2017 to 14 July 2017. This type of research is a laboratory observation that aims to determine the criteria for assessing the impression of the number of leukocytes on a peripheral blood smear. Data analysis using statistical analysis is the average and standard deviations to determine the impression of the number of leukocytes and use 3 inspection zones. The results of this study obtained results in zone IV the number of leukocyte impressions said to be sufficient was 7-10, in zone V the number of leukocyte impressions said to be sufficient was 4-9, and in zone VI the number of leukocyte impressions said to be sufficient was 3-8.  

scholarly journals Platelet Phagocytosis by Neutrophils, Platelets Lack of Granules and Giant Platelets Result in Pseudothrombocytopenia

2021 ◽  
Author(s):  
Ya Zhu ◽  
Junyang Zhou ◽  
Li Sun ◽  
Feibo Guo ◽  
Yan Ding ◽  
...  
Keyword(s):  
Platelet Count ◽  
Peripheral Blood ◽  
Blood Smear ◽  
Sodium Citrate ◽  
Clinical Status ◽  
Peripheral Blood Smear ◽  
Giant Platelets ◽  
Platelet Morphology ◽  
Specific Disorders ◽  
Tuberculosis Therapy

Abstract Pseudothrombocytopenia (PTCP) is a condition in which the decreased platelet count does not agree with the clinical status of the patient, can lead to misdiagnose, unnecessary tests, unnecessary treatment. The present case describes a 73-year-old man suffered with pulmonary tuberculosis, treated with anti-tuberculosis therapy (isoniazid, rifampicin, pyrazinamide, ethambutol, 2HRZE/4HR). One month later, the patient had a significant decrease in platelets (101 to 56 x109/L). Peripheral blood smear showed that 28% platelets were phagocytosis by neutrophils, 26% platelets were lack of granules and 6% platelets’ volume increased significantly. When the anticoagulant was changed from EDTA to sodium citrate, there was no change in the above phenomenon. By manual count, the value of platelets was 113 x 109/L. After the completion of anti-tuberculosis therapy, platelet morphology gradually returned to normal. HRZE treatment may cause platelet morphology abnormal, resulting in PTCP. In such cases, we should regularly review the peripheral blood smear to ensure the accuracy of the results and avoid unnecessary examination and treatment. The emergence of PTCP may does not mean the presence of specific disorders.

A Case of Clopidogrel Induced TTP Recurring After Four Years

Blood ◽  
2010 ◽  
Vol 116 (21) ◽  
pp. 4678-4678
Author(s):  
Nanda K. Methuku ◽  
Abhinav B. Chandra ◽  
Anuradha Belur ◽  
Lech Dabrowski
Keyword(s):  
Platelet Count ◽  
Renal Insufficiency ◽  
Peripheral Blood ◽  
Blood Smear ◽  
Reticulocyte Count ◽  
Conflicts Of Interest ◽  
Peripheral Blood Smear ◽  
Severe Thrombocytopenia ◽  
Platelet Counts ◽  
Multiple Organs

Abstract Abstract 4678 Case description - A 61 year old woman was started on clopidogrel after having PTCA with stent placement in February 2006. Four weeks after starting clopidogrel she developed thrombocytopenia with platelet nadir of 17,000. Her LDH was 700 IU/L and she was anemic with hemoglobin of 7.4 gm/dl with elevated reticulocyte count. Peripheral blood smear showed schistocytes and diagnosis of TTP secondary to clopidogrel was made. She did not have renal insufficiency. Clopidogrel was discontinued and patient was started on plasmapheresis with recovery of platelet counts. Early attempts in weaning plasmapheresis resulted in drop in platelet count and Rituximab was given to the patient weekly for four weeks. Subsequently, patient was weaned off plasmapheresis. For four years patient was followed periodically with CBC showing platelet counts greater than 250,000. In May 2010, four years after initial event patient was admitted to hospital for abdominal pain and found to have splenic infarcts. Subsequently, she also developed bilateral cerebral infarcts. Platelet count had decreased to less than 100,000. Her LDH was elevated at 419 IU/L. Reticulocyte count was 2.3%. Peripheral blood smear revealed significant number of schistocytes. There was no renal insufficiency or fever. Trans-esophageal echocardiogram (TEE) was done that did not reveal any vegetations. Patient was diagnosed as having recurrence of TTP and started on plasmapheresis with recovery in platelet counts. Pt was also treated with Rituximab. Discussion- We describe a case of TTP initially occurring within weeks of starting clopidogrel. Patient was treated with plasmapheresis and Rituximab and clopidogrel was discontinued. Patient had recurrence after four years as manifested by infarcts in multiple organs, with mild thrombocytopenia, elevated LDH and significant number of schistocytes on peripheral blood smear. It is very uncommon for clopidogrel associated TTP to recur after such a prolonged period of 4 years. Most cases of clopidogrel associated TTP have mild thrombocytopenia. This patient had severe thrombocytopenia on first presentation of TTP but had mild thrombocytopenia on recurrence. This case illustrates the importance of extended follow up and high index of suspicion for TTP as delays in initiation of plasmapheresis has a poor clinical outcome. Disclosures: No relevant conflicts of interest to declare.

Leukopenie – ein diagnostischer Leitfaden für die Praxis

2017 ◽  
Vol 142 (23) ◽  
pp. 1744-1749 ◽  
Author(s):  
Deborah Christen ◽  
Tim Brümmendorf ◽  
Jens Panse
Keyword(s):  
Bone Marrow ◽  
Platelet Count ◽  
Blood Smear ◽  
Peripheral Blood Smear ◽  
Blood Cell Count ◽  
Essential Step ◽  
Cell Counts ◽  
Life Threatening ◽  
Red Blood Cell Count ◽  
The Right

AbstractReasons for leukopenia can be numerous. To get close to the diagnosis it’s always useful to check previous blood counts of the patient to get a feeling for the dynamic development of the leukopenia. Furthermore, it’s important to check the red blood cell count and platelet count as well; a bi- or a pancytopenia usually implies an insufficient production in the bone marrow. Nevertheless, a manual counted peripheral blood smear is an essential step towards the right diagnosis in leukopenia: Beside cell counts of the single subgroups of leucocytes it also provides information on potential causes such as dysplasia.Leukopenia can be life-threatening for the patient especially if the patient presents with an agranulocytosis and fever: In this case admission is mandatory and the patient has to be treated immediately with broad-spectrum antibiotics to reduce mortality.

scholarly journals Perinatal Management for a Pregnant Woman with anMYH9Disorder

2016 ◽  
Vol 2016 ◽  
pp. 1-3
Author(s):  
Yuka Yamashita ◽  
Rei Matsuura ◽  
Shinji Kunishima ◽  
Yoshie Oikawa ◽  
Hirotsugu Ariizumi ◽  
...  
Keyword(s):  
Platelet Count ◽  
Genetic Counseling ◽  
Pregnant Woman ◽  
Genetic Analysis ◽  
Blood Smear ◽  
Peripheral Blood Smear ◽  
Inheritance Pattern ◽  
Immunofluorescence Analysis ◽  
Established Method ◽  
Perinatal Management

We diagnosed a primipara woman with anMYH9disorder during her pregnancy. A peripheral blood smear with an immunofluorescence analysis is the established method of diagnosingMYH9disorders. We provided genetic counseling, as required, which included apprising the woman of the inheritance pattern, the importance of a genetic analysis, and the potential delivery risks for the patient and her offspring. Given that the potential delivery risks are reportedly low, special perinatal management is not necessary for patients with anMYH9disorder whose platelet count is above 5.0 × 104/μL, except for rapid blood access.

scholarly journals PREVALENCE OF HUMAN MALARIA

2016 ◽  
Vol 23 (06) ◽  
pp. 655-659
Author(s):  
Muhammad Zafar Majeed ◽  
Muhammad Shahbaz Hussain ◽  
Faiza Sarwar
Keyword(s):  
Nervous System ◽  
Platelet Count ◽  
Malaria Infection ◽  
Blood Smear ◽  
Monsoon Season ◽  
Peripheral Blood Smear ◽  
Blood Samples ◽  
Human Malaria ◽  
High Prevalence ◽  
Thick Smear

Malaria is one of the devastating diseases worldwide. More than 3 billion peoplelive under the threat of malaria in endemic countries and kills more than one million each year.Malaria leads to multiple hematological (thrombocytopenia) and other abnormalities like renalsystem, nervous system with increased morbidity and mortality. Aim: The present study wasconducted to determine the prevalence of human malaria, its correlation with thrombocytopeniaand treatment in patients of District Rahim Yar Khan. Materials and Methods: A total of 200patients including 140 males and 60 females were the part of our study. Blood samples collectionwas done during September to November following monsoon season. Patients were diagnosedthrough peripheral blood smear. Both P. falciparum and P. vivax parasites against 300 white bloodcells (WBCs) were examined on the thick smear. Platelet count was done by using an automatedcell count analyzer. A platelet count of less than 150 x109/L defined thrombocytopaenia. Firstline of treatment was Chloroquine in cases of Plasmodium vivax whereas Neo fansidar incases of Plasmodium falciparum. Results: Gender wise distribution of patients was 140 (70%)males and 60(30%) females. We had 74 (37%) patients from urban and 126 (63%) from ruralpopulation. Malaria was most frequent 64% by P.vivax and 36% by P.falciparum. Fever was highduring admission to hospital and after usage of antimalarials recovery and improvement innumber of platelets was noted. Conclusion: The high prevalence rate of P. vivax pose a majorhealth hazard but of P. falciparum also may lead to serious complications. The high frequencyof human malaria infection should be a major concern for authorities in the fight against malariacontrol programs in Pakistan.

Penentuan Kriteria Penilaian Kesan Jumlah Leukosit Pada Pemeriksaan Apusan Darah Tepi

2018 ◽  
Vol 3 (2) ◽  
pp. 118-127
Author(s):  
Dzikra Arwie ◽  
Islawati
Keyword(s):  
Data Analysis ◽  
Statistical Analysis ◽  
Blood Cells ◽  
Blood Smear ◽  
White Blood Cells ◽  
Peripheral Blood Smear ◽  
Field Of View ◽  
Laboratory Observation ◽  
Number Of Cells

Leukocytes or white blood cells have a characteristic characteristic of different cells. Determination of the impression of the number of leukocytes is determined in the number of cells in the field of view. While the number of viewable field cells expressed is still quite varied. The purpose of this study was to determine the number of leukocytes in the field of view and expressed the impression of a sufficient amount. This research was conducted at the Laboratory of Health Analyst Department Panrita Husada Bulukumba on 9 April 2017 to 14 July 2017. This type of research is a laboratory observation that aims to determine the criteria for assessing the impression of the number of leukocytes on a peripheral blood smear. Data analysis using statistical analysis is the average and standard deviations to determine the impression of the number of leukocytes and use 3 inspection zones. The results of this study obtained results in zone IV the number of leukocyte impressions said to be sufficient was 7-10, in zone V the number of leukocyte impressions said to be sufficient was 4-9, and in zone VI the number of leukocyte impressions said to be sufficient was 3-8.

scholarly journals Low platelet counts in pregnancy: an alarm signal for abruption!

2018 ◽  
Vol 7 (3) ◽  
pp. 1191 ◽  
Author(s):  
Anjali Mundkur ◽  
K. P. Murali Krishnan Nambiar ◽  
Lavanya Rai
Keyword(s):  
Platelet Count ◽  
Pregnant Women ◽  
Connective Tissue Disorder ◽  
Severe Thrombocytopenia ◽  
Related Condition ◽  
Alarm Signal ◽  
Hematologic Disorder ◽  
Gestational Thrombocytopenia ◽  
In Pregnancy ◽  
Do So

Background: Thrombocytopenia, defined as a platelet count less than 150 million/mm3, affects 6% to 10% of all pregnant women and other than anemia is the most common hematologic disorder in pregnancy.Methods: We studied all patients with thrombocytopenia in pregnancy from June 2012 to May 2013. There were 86 patients recruited into the study. Pregnant women with preeclampsia and suspected connective tissue disorder were also screened for thrombocytopenia. All women with platelet count of <1.50,000/µl during the study period were included.Results: Patients were grouped in to mild thrombocytopenia (platelet 100,000-149,999/µl), moderate thrombocytopenia (platelet 50,000-99,999/µl) and severe thrombocytopenia (platelet <49,999/µl. Pregnancy specific cause of thrombocytopenia was in 63 (73.2%) women and non-pregnancy specific were in 23(26.7%) patients.Conclusions: Preeclampsia and HELLP syndrome is more common cause of thrombocytopenia in pregnancy. Abruption can occur in patients with severe thrombocytopenia. Though platelet count is not routinely done in pregnancy it is advisable to do so as it may help in detecting gestational thrombocytopenia or other immune related condition.

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