An analysis of Mean Arterial Pressure, Roll Over Test and Body Mass Index as Predictors of Hypertension in Pregnancy

Background Whether or not norepinephrine infusions for support of hemodynamic status in patients with septic shock should be weight based is unknown. This situation is particularly pertinent in patients who are extremely overweight or obese. Objective To compare dosing requirements and effect of norepinephrine on blood pressure in obese and nonobese patients with septic shock. Methods In a retrospective cohort study, data on adult patients with septic shock who received norepinephrine infusion for support of hemodynamic status in a tertiary care, academic medical center were analyzed. Patients were categorized as obese (body mass index ≥ 30) or nonobese (body mass index < 30). The primary outcome was dosing requirements of norepinephrine at 60 minutes after the start of the infusion. The secondary outcome was the log-transformed ratio of mean arterial pressure to norepinephrine. Results The final cohort consisted of 100 obese and 100 nonobese patients. Mean norepinephrine infusion rate at 60 minutes was 0.09 (SD, 0.08) μg/kg per minute in the obese group and 0.13 (SD, 0.14) μg/kg per minute in the nonobese group (P = .006). The non–weight-based dose at 60 minutes was 9 μg/min in obese patients and 8 μg/min in nonobese patients (P = .72). The log transformed mean arterial pressure to norepinephrine ratio at 60 minutes was 2.5 (SD, 0.9) in obese patients and 2.5 (SD, 0.8) in nonobese patients (P = .54) Conclusions Compared with nonobese patients, obese patients with septic shock require lower weight-based doses of norepinephrine and similar total norepinephrine doses.

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The M235T Variant of the Angiotensinogen Gene and the Body Mass Index Are Useful Markers for Prevention of Hypertension in Pregnancy: A Tree-Based Analysis of Gene-Environment Interaction

Seminars in Thrombosis and Hemostasis ◽

10.1055/s-2002-36690 ◽

2002 ◽

Vol 28 (6) ◽

pp. 501-506 ◽

Cited By ~ 6

Author(s):

Gen Kobashi ◽

Akira Hata ◽

Koichi Shido ◽

Kaori Ohta ◽

Hideto Yamada ◽

...

Keyword(s):

Body Mass Index ◽

Body Mass ◽

The Body ◽

Environment Interaction ◽

Gene Environment Interaction ◽

Angiotensinogen Gene ◽

Hypertension In Pregnancy ◽

Gene Environment ◽

Prevention Of Hypertension ◽

In Pregnancy

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Role of Body Mass Index, Mean Arterial Pressure, and Uterine Artery Doppler at 11-14 Weeks in Prediction of Pregnancy-Induced Hypertension in Low-Risk Population

International Journal of Current Research and Review ◽

10.31782/ijcrr.2021.13928 ◽

2021 ◽

Vol 13 (09) ◽

pp. 63-70

Author(s):

Kumari M ◽

Das S ◽

Chanania K ◽

Panda AK

Keyword(s):

Body Mass Index ◽

Mean Arterial Pressure ◽

Arterial Pressure ◽

Body Mass ◽

Uterine Artery ◽

Low Risk ◽

Pregnancy Induced Hypertension ◽

Uterine Artery Doppler ◽

Induced Hypertension

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The Role of Mean Arterial Pressure (MAP) Roll Over Test (ROT) and Body Mass Index (BMI) in Preeclampsia Screening in Indonesia

Indian Journal of Public Health Research & Development ◽

10.37506/v11/i1/2020/ijphrd/193977 ◽

2020 ◽

Vol 11 (1) ◽

pp. 1056

Author(s):

Dwi Putri Rahayu Tampubolon ◽

Lilik Herawati ◽

Anon Nursalam ◽

Anon Ernawati

Keyword(s):

Body Mass Index ◽

Mean Arterial Pressure ◽

Arterial Pressure ◽

Body Mass

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Abstract P101: Hypertension in Pregnancy and Risk of Hypertension in Later Life: The Bogalusa Heart Study

Circulation ◽

10.1161/circ.129.suppl_1.p101 ◽

2014 ◽

Vol 129 (suppl_1) ◽

Author(s):

Shengxu Li ◽

Xu Xiong ◽

Camilo Fernandez ◽

Wei Chen ◽

Sathanur R Srinivasan ◽

...

Keyword(s):

Blood Pressure ◽

Body Mass Index ◽

Body Mass ◽

Previous History ◽

Later Life ◽

Bogalusa Heart Study ◽

Hypertension In Pregnancy ◽

Heart Study ◽

History Of ◽

In Pregnancy

Background: Few studies have examined whether hypertension in pregnancy imposes long-term cardiovascular risk compared to a normal pregnancy. The objective of this study was to examine if previous history of hypertension in pregnancy is a risk for hypertension after pregnancy. Methods: A case-control analysis was performed using the Bogalusa Heart Study database. Cases were defined as women whose systolic blood pressure ≥140 mmHg or diastolic ≥ 90 mmHg, or having hypertension treatment. Controls were defined as women with normal blood pressure. After exclusions, 604 women (67% white and 33% black, aged 32-44 years) were included for analysis. Univariable and multivariable logistic regression were used to estimate the odds ratio (OR) and 95% confidence interval (CI). Results: The prevalence of hypertension in women was 12.1% (73/604). Hypertensive women had higher proportion of previous history of hypertension in pregnancy (25/73, 34%) than normotensive controls (83/531, 13.7%), with an OR of 2.81 (95% CI: 1.64-4.81). After adjustment for age, race, body mass index and smoking, adjusted OR (aOR) of having previous history of hypertension in pregnancy for developing hypertension later was 1.36 (1.00-3.75). In addition, age, black ethnicity and body mass index were associated with hypertension, with aORs of 1.16 (1.09-1.25), 3.73 (2.13-6.52), and 1.09 (1.05-1.13), respectively. Conclusions: Hypertension in pregnancy may be associated with an increased risk of hypertension in later life. Further studies are needed to separate the effect of pregnancy-induced hypertension and pre-exiting chronic hypertension on the subsequent risk of hypertension later in life.

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Correlation of Body Mass Index, Mean Arterial Pressure with Peak Expiratory Flow Rate in Healthy Individuals- A Descriptive Study

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2021/48047.14742 ◽

2021 ◽

Author(s):

Tanuj Mathur ◽

Dileep Kumar Verma ◽

Sunita Tiwari ◽

Narsingh Verma ◽

Ranjana Singh

Keyword(s):

Body Mass Index ◽

Mean Arterial Pressure ◽

Arterial Pressure ◽

Body Mass ◽

Peak Expiratory Flow ◽

Flow Rate ◽

Peak Expiratory Flow Rate ◽

Healthy Individuals ◽

Cross Sectional ◽

Expiratory Flow

Introduction: Modern lifestyle has resulted in an increased prevalence of cardiovascular and respiratory diseases along with being overweight. An interaction between the three factors has also been demonstrated. Aim: The study aimed to assess the relationship of Body Mass Index (BMI), Mean Arterial Pressure (MAP) and Peak Expiratory Flow Rate (PEFR) in healthy individuals. Materials and Methods: This cross-sectional, observational study was done in the Department of Physiology, KGMU, Lucknow from 30 July 2019 to 30 July 2020. Forty healthy individuals, aged 18-35 years were assessed for height, weight, blood pressure and spirometric parameter of PEFR. PEFR was chosen as it was a reliable representative of airways functioning. PEFR reflects proximal airway calibre changes which might be due to effect of airway geometry. A correlation test was run to test the relation between BMI and PEFR and MAP and PEFR. Results: A weak correlation (r=-0.136) was noted between BMI and PEFR indicating that as BMI increased, PEFR compromised. A linear correlation was observed between MAP and PEFR. Conclusion: The present study confirms a weak association of BMI and MAP with PEFR.

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Sex Differences in Correlates of Steady State and Pulsatile Component of Blood Pressure

Clinical Science ◽

10.1042/cs0910385 ◽

1996 ◽

Vol 91 (4) ◽

pp. 385-389 ◽

Cited By ~ 1

Author(s):

A. Scuteri ◽

A. M. Cacciafesta ◽

M. G. Di Bernardo ◽

A. M. De Propris ◽

D. Recchi ◽

...

Keyword(s):

Blood Pressure ◽

Body Mass Index ◽

Regression Analysis ◽

Mean Arterial Pressure ◽

Arterial Pressure ◽

Multiple Regression Analysis ◽

Multiple Regression ◽

Body Mass ◽

Pulse Pressure ◽

Coronary Insufficiency

1. The aim of the present study was to evaluate whether metabolic factors are linked to the steady component and the pulsatile component of blood pressure, evaluated as mean arterial pressure and pulse pressure respectively, in a sex-specific manner. 2. A cohort of 299 subjects (152 males, 147 females; 25–80 years of age) was studied. Patients presenting congestive heart failure, coronary insufficiency, severe valvular heart disease, neurological accident in the last 6 months, renal or respiratory failure, cancer, diabetes mellitus or acute infectious disease were excluded. None of the women was taking oral contraceptives or oestrogen supplementation. All cardioactive drugs were withdrawn at least 2 weeks before the subjects entered the study. 3. Men presented higher mean arterial pressure (120 ± 15 compared with 115 ± 16 mmHg, P < 0.01) and lower pulse pressure values (63 ± 16 compared with 67 ± 18 mmHg, P < 0.05) than women. In men, no significant relation between mean arterial pressure and the tested variables was detected; multiple regression analysis demonstrated that age contributed independently to the model for pulse pressure with a multiple r2 of 0.10 (P < 0.01). In women, body mass index contributed independently to the model for mean arterial pressure, with a multiple of 0.12 (P < 0.005); age and, to a lesser extent, body mass index, glycaemia and triglyceridaemia persisted as independent determinants of pulse pressure at the multiple regression analysis, with a multiple r2 of 0.20 (P < 0.001). 4. Our findings suggest that metabolic risk factors are associated differently with pulse pressure and mean arterial pressure values in the two sexes.

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