scholarly journals Synthesis, characterization, and cytotoxic evaluation of iron oxide nanoparticles functionalized with galactomannan

2021 ◽  
Author(s):  
Francisco R S Mendes ◽  
Fernanda N Rodrigues ◽  
Nidyedja G G Gonçalves ◽  
Mateus T Aerre ◽  
Kelvi W E Miranda ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Thermogravimetric Analysis ◽  
Cytotoxic Activity ◽  
Iron Oxide Nanoparticles ◽  
Chemical Constituents ◽  
Average Diameter ◽  
Oxide Nanoparticles ◽  
X Ray Diffraction ◽  
Hek 293 ◽  
Co Precipitation

Iron nanoparticles (FeNP) present excellent magnetic properties and chemical stability, and for this reason, they are often configured into materials for a variety of potential uses in medical, biotechnological, and other applications. In this work, iron oxide nanoparticles functionalized with galactomannan (FeNP/Gal) from Caesalpinia pulcherrima were synthesized and submitted to characterization and evaluation of the cytotoxic activity. The functionalized nanoparticles were synthesized by co-precipitation and subjected to a process of surface modification with galactomannan and epichlorohydrin. These nanomaterials were characterized using infrared spectroscopy, X-ray diffraction (XRD), thermogravimetric analysis (TGA), differential thermogravimetric analysis (DTA), and scanning electron microscopy (SEM). 1D and 2D nuclear magnetic resonance (NMR) spectroscopy were also used in the structural analysis of the galactomannan. In addition, in vitro study was carried out to evaluate the cytotoxic activity of the FeNP/Gal nanoparticles on human cells of the HEK-293 strain (ATCC® CRL-1573). The FeNP/Gal nanoparticles had an average diameter of 13 ± 2 nm as opposed to 11 ± 2 nm for unreacted FeNP. The infrared spectrum of the FeNP/Gal nanoparticles presents characteristic absorbance bands of their chemical constituents, confirming that the iron oxide nanoparticles were functionalized with galactomannan. The cytotoxicity assay for the FeNP/Gal nanoparticles did not show significant cytotoxicity against HEK 293-Human embryonic kidney cell lines below 800 µg/mL However, this study points out the possibility of using hemicellulose and other plant-based polysaccharides to produce nanostructured materials for ​​tissue engineering and other biomedical applications.

scholarly journals Unravelling the growth mechanism of the co-precipitation of iron oxide nanoparticles with the aid of synchrotron X-Ray diffraction in solution

Nanoscale ◽  
2019 ◽  
Vol 11 (14) ◽  
pp. 6620-6628 ◽  
Author(s):  
Alec P. LaGrow ◽  
Maximilian O. Besenhard ◽  
Aden Hodzic ◽  
Andreas Sergides ◽  
Lara K. Bogart ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Formation Mechanism ◽  
Growth Mechanism ◽  
Oxide Nanoparticles ◽  
X Ray Diffraction ◽  
X Ray ◽  
Co Precipitation

The formation mechanism of iron oxide nanoparticles reveals an initial segregation into ferrihydrite seeds and a Fe2+ rich growth reservoir.

The Effect of Synthesis Method on the Physico-Chemical Properties of Magnetite Iron Oxide Nanoparticles

2013 ◽  
Vol 701 ◽  
pp. 212-216
Author(s):  
Hussein Mohd Zobir ◽  
Samuri Nor Suzariana ◽  
Shaari Abdul Halim
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Ultrasonic Method ◽  
Synthesis Method ◽  
Chemical Properties ◽  
Superparamagnetic Iron Oxide ◽  
Average Diameter ◽  
Oxide Nanoparticles ◽  
Physico Chemical ◽  
Co Precipitation

Superparamagnetic iron oxide nanoparticles were synthesized using co-precipitation, hydrothermal and ultrasonic routes from Fe2+/Fe3+ions and NaOH. The average diameter for the sample prepared using co-precipitation, hydrothermal and ultrasonic method is 33, 9 and 30 nm, respectively with surface area of 85, 117 and 87 m2/g, respectively. Although the results showed all the magnetite nanoparticles were superparamagnetic, but their saturation magnetization and coercitivity are different, depending on the method of synthesis. This study shows that method of synthesis is important that influence the physico-chemical properties of the resulting magnetite iron oxide nanoparticles.

scholarly journals Analysis of Organochlorine Pesticides in Drinking Water and their Degradation by Synthesized Iron oxide Nanoparticles

2020 ◽  
Vol 32 (5) ◽  
pp. 1177-1182
Author(s):  
Bharti ◽  
J.S. Jangwan ◽  
Amrish Kumar ◽  
Vivek Kumar
Keyword(s):  
Drinking Water ◽  
Iron Oxide ◽  
Organochlorine Pesticides ◽  
Iron Oxide Nanoparticles ◽  
Precipitation Method ◽  
Oxide Nanoparticles ◽  
X Ray Diffraction ◽  
Detection Analysis ◽  
Diffraction Patterns ◽  
Co Precipitation

This study reports the analysis of drinking water sources of river Krishni catchment, contaminated by organochlorine pesticides. Iron oxide nanoparticles had been synthesized through co-precipitation method and utilized for the degradation of organochlorine pesticides using advanced oxidation processes. The sharp and narrow peaks of X-ray diffraction patterns revealed the crystalline nature of synthesized iron oxide nanoparticles having size less than 100 nm. The nanoparticles were also characterized using TEM, UV-Vis and IR spectral analysis. Liquid-liquid extraction and GC-MS were used for the detection analysis of pesticides. GC-MS technique was used for further quantitative analysis of 19 pesticides. The degradation analysis showed the maximum amount of degradation (up to 98.38 %) of organochlorine pesticides.

Synthesis of Iron Oxide Nanoparticles by Different Methods and Study of their Properties

2015 ◽  
Vol 230 ◽  
pp. 108-113 ◽  
Author(s):  
O.V. Yelenich ◽  
S.O. Solopan ◽  
T.V. Kolodiazhnyi ◽  
Jean Marc Greneche ◽  
Anatolii G. Belous
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Zero Field ◽  
X Ray Diffraction ◽  
Magnetic Studies ◽  
Brij 35 ◽  
Cryochemical Synthesis ◽  
Specific Loss Power ◽  
Triton X

In this work, iron oxide nanoparticles have been synthesized by precipitation in diethylene glycol, by cryochemical synthesis, in microemulsions using surfactants Triton X-100, Brij-35 and CTAB. Comparative spectroscopic, thermal, X-ray diffraction, 57Fe zero-field Mössbauer and magnetic studies of the synthesized nanoparticles have been carried out. Magnetic fluids prepared from synthesized nanopowders have been characterized by calorimetric measurements of specific loss power (SLP).

scholarly journals Preparation and Characterization of Polyethylene Glycol Coating Iron Oxide Nanoparticles for Curcumin Delivery

2019 ◽  
Vol 31 (8) ◽  
pp. 1719-1723
Author(s):  
Nguyen Thi Thanh Thuy ◽  
Le Duc Anh ◽  
Nguyen Huu Tri ◽  
Cu Van Hoang ◽  
Nguyen Anh Nhut
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Sonication Time ◽  
X Ray Diffraction ◽  
Target Drug Delivery ◽  
Target Drug ◽  
Fe3o4 Nps ◽  
Average Size

The PEG-coated iron oxide nanoparticles (Fe3O4 NPs-PEG) was synthesized by coprecipitation and ultrasonication method. X-ray diffraction results exhibited that the average size of Fe3O4 NPs-PEG was 19.10 nm, which was further confirmed in TEM imaging. In addition, sonication time and curcumin concentration were studied to evaluate the efficiency of loading curcumin onto Fe3O4 NPs-PEG. Further, statistical optimization using response surface methodology (RSM) has shown curcumin concentration (0,01% w/v) and sonication time (21 min) for maximal curcumin loading (0.37 mg/g). Along with the magnetization studies, the immobilization of curcumin onto the Fe3O4 NPs-PEG was characterized by UV, FTIR and SEM. The results showed that the curcumin loaded PEG coated iron oxide nanoparticles could potentially be used for magnetically target drug delivery.

Sonochemical Synthesis of Silica Coated Super Paramagnetic Iron Oxide Nanoparticles

2013 ◽  
Vol 756 ◽  
pp. 74-79 ◽  
Author(s):  
Bashiru Kayode Sodipo ◽  
Azlan Abdul Aziz
Keyword(s):  
Iron Oxide ◽  
Silica Nanoparticles ◽  
Iron Oxide Nanoparticles ◽  
Ph Value ◽  
Superparamagnetic Iron Oxide ◽  
Silica Nanoparticle ◽  
Precipitation Method ◽  
Oxide Nanoparticles ◽  
Sonochemical Method ◽  
Co Precipitation

Superparamagnetic iron oxide nanoparticles (SPION) of sizes 5 to10 nm were synthesized by the co-precipitation method. They are coated with silica nanoparticles using sonication method. The SPION was produced under the optimum pH of 10, peptized in acidic medium and redispersed in water. The silica nanoparticles were produced through the Stöbermethod. Sonochemical coating of silica nanoparticle on the SPION was successfulat a pH value lower than 5. Otherwise, at higher pH value (but lower than point zero charge (PZC)), the SPION were found to be unstable. Fast hydrolysis of triethoxyvinylsilane(TEVS) shows that silica forms its own particles without coating onto the surfaces of the SPION. Under optimized experimental condition, sonochemical method of coating silica nanoparticles onto the SPION can be considered as an alternative for effective and prompt method that rely mainly on pH of the suspension.

COLLOIDAL STABILITY AND MONODISPERSIBLE MAGNETIC IRON OXIDE NANOPARTICLES IN BIOTECHNOLOGY APPLICATION

2013 ◽  
Vol 12 (06) ◽  
pp. 1330002 ◽  
Author(s):  
K. SHAMILI ◽  
E. M. RAJESH ◽  
R. RAJENDRAN ◽  
S. R. MADHAN SHANKAR ◽  
M. ELANGO ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Colloidal Stability ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Fluid Hyperthermia ◽  
Magnetic Iron Oxide ◽  
Magnetic Resonance Imaging Mri ◽  
Co Precipitation

Magnetic iron oxide nanoparticles are promising material for various biological applications. In the recent decades, magnetic iron oxide nanoparticles (MNPs) have great attention in biomedical applications such as drug delivery, magnetic resonance imaging (MRI) and magnetic fluid hyperthermia (MFH). This review focuses on the colloidal stability and monodispersity properties of MNPs, which pay more attention toward biomedical applications. The simplest and the most promising method for the synthesis of MNPs is co-precipitation. The biocompatible MNPs are more interested in MRI application. This review also apportions synthesis, characterization and applications of MNP in biological and biomedical as theranostics and imaging.

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