Scientific approaches to the selection of biologically active substances of animal and plant origin for metabolic syndrome correction

2020 ◽  
pp. 18-21
Author(s):  
M.A. Aslanova ◽  
E.R. Vasilevskaya ◽  
E.A. Kotenkova ◽  
I.M. Chernukha ◽  
L.V. Fedulova ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Plant Origin ◽  
Active Substances ◽  
Selection Of

scholarly journals Study on domestic market of medicinal products of plant origin

2018 ◽  
pp. 30-36
Author(s):  
V. M. Minarchenko ◽  
A. Yu. Butko
Keyword(s):  
Medicinal Plants ◽  
Raw Materials ◽  
Domestic Market ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Herbal Remedies ◽  
Plant Origin ◽  
Resource Base ◽  
Natural Resource Base ◽  
Active Substances

The popularity of herbal remedies and medicines, with the participation of biologically active substances from plants is traditionally high. The annual increase of the domestic market for herbal remedies is due to the preservation and modernization of production capacities for processing of medicinal vegetative raw materials in Ukraine, introduction of modern scientific developments, a large natural resource base of medicinal plants and attracting investments in the development of this industry. The aim of our work was the study of the domestic market of medicines of plant origin, which includes herbal remedies, substances and preparations with the participation of biologically active substances from plants. The object of the study was domestic medicines of plant origin that are registered in Ukraine for 2012–2017. The study used the analytical, statistical methods, and the results of its own resource studies of medicinal plants. Phytopharmaceutical market of Ukraine is actively developing due to the attraction of new types of medicinal plants and expanding the range of medicines. The number of domestic drugs with the participation of biologically active substances from plants has increased by 17.4% compared with 2014. It is established that as of 1 January 2017 in Ukraine was 1 141 the form of medicinal drugs of plant origin. Of them: 645 – domestic products, 496 – foreign. Most of the herbal drugs in the pharmaceutical market of Ukraine are made from wild and cultivated domestic raw materials.

Substantiation and Selection of Promising Medicinal plants for prevention of diseases of Springer cows (Review)

2021 ◽  
pp. 6139-6146
Author(s):  
Elena Victorovna Ulrikh ◽  
Tatyana Vladimirovna Zubova ◽  
Olga Borisovna Konstantinova ◽  
Oksana Vladimirovna Smolovskaya ◽  
Ekaterina Aleksandrovna Izhmulkina
Keyword(s):  
Medicinal Plants ◽  
Lower Risk ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Allergic Reactions ◽  
Therapeutic Action ◽  
Long Time ◽  
Active Substances ◽  
Selection Of

Medicinal plants and phytopreparations on their basis have been for a long time used for prevention of numerous diseases of springer cows. Phytobiotics supply a set of biologically active substances into organism, including micro- and macroelements. In comparison with synthetic preparations, the phytobiotics and bioadditives based on herbal stuff are characterized by certain advantages: lower risk of allergic reactions, soft effect, wide therapeutic action, efficiency and safety for use upon management of springer cows.

scholarly journals Development of methods for analysis of the amount of flavonoids and their stability study in the combined dental gel

2021 ◽  
pp. 3-10
Author(s):  
Yu. Maslii ◽  
A. Materiienko ◽  
O. Ruban ◽  
I. Bezruk ◽  
L. Ivanauskas
Keyword(s):  
Stability Study ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Plant Origin ◽  
Active Components ◽  
Drug Substances ◽  
The Stability ◽  
And Storage ◽  
Active Substances

An important aspect in the pharmaceutical development of dental medicines is to provide them with a prolonged therapeutic effect while reducing the side effects of drug substances and the possibility of long-term use. This can be achieved by using active components of plant origin. Aim. To develop methods for analyzing biologically active substances in the composition of a new combined dental gel. Materials and methods. The study object was a dental gel containing “Phytodent” complex tincture (PJSC “CPP Chervona zirka”, Ukraine). Based on the analysis of the composition of the tincture it was proposed to carry out standardization by the amount of biologically active substances, namely flavonoids. Identification was carried out by TLC, while the quantitative determination by absorption spectrophotometry, the ultraviolet and visible method by the reaction with aluminum chloride using the standard method calculated with reference to rutin and the absorbance measurement at 406 nm. Results and discussion. As a result of the research, the methods for the analysis of flavonoids in the composition of the new combined gel have been developed. The spectrophotometric method developed is characterized by specificity, accuracy, precision and linearity with r = 0.9998. One of the important issues when using components of plant origin is their stability both during preparation and storage. Using the method developed the stability of flavonoids has been studied depending on pH changes of the carbomer-based dental gel. Conclusions. It has been determined that the methods developed are easily reproducible and allow to identifying and quantifying flavonoids in the dental gel. It has been found that a stable content of flavonoids is characteristic of the carbomer-based gel neutralized to pH values from 5.0 to 6.0.

scholarly journals CRITERIA FOR SELECTING AEROSOL PACKAGING AND DETERMINING THE OPTIMUM QUANTITY OF A PROPELLANT

2020 ◽  
Vol 4 ◽  
pp. 15-20
Author(s):  
Bogdan Putyatin ◽  
Ekaterina Kunitsia ◽  
Natalia Sytnik
Keyword(s):  
Essential Oils ◽  
Mass Fraction ◽  
Negative Impact ◽  
Excess Pressure ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Correct Selection ◽  
Cosmetic Products ◽  
Active Substances ◽  
Selection Of

Development of a new generation of functional antiage cosmetics is a most important area of cosmetic industry development. An integral part of such products are biologically active substances (BAS) with essential oils, being among the sources of which. Each essential oil is characterized by a well balanced unique composition of biologically active substances. Development of new cosmetic products consists of correct selection of the required composition of components with required properties and selection of a suitable package, preserving product properties throughout its shelf life. During production of cosmetic products in aerosol package a number of issues are solved, unlike with antiage-products in form of creams in customary tubes. The degree of oxidation-reduction reactions, having negative impact on the properties of essential oils, is substantially reduced. The concentration providing for the optimum degree of evacuation and excess pressure in the packaging are essential issues. The aim of this research is to determine the degree of evacuation of the contents, excess pressure, and mass fraction of a propellant in the product test samples to find the samples of aerosol package with optimum parameters. A number of tests to determine the degree of evacuation of the contents from aerosol package, excess pressure and a mass fraction of a propellant have been performed. The greatest degree of evacuation of products was observed with mass fraction of propellant of 13.79%. Based on the results of the tests for excess pressure in aerosol packaging, it has been found, that with mass fraction of a propellant of 13.79% excess pressure is 0.4 MPa, which was taken as an optimum value. The test showed that the mass of a propellant of 16 g evacuates the product from aerosol package to the maximum extent and does not exceed the acceptable limits for excess pressure (0.2–0.6 MPa)

scholarly journals SELECTION OF AN EXTRACTANT FOR ISOLATION OF BIOLOGICALLY ACTIVE COMPOUNDS FROM A HEDYSARUM NEGLECTUM

2020 ◽  
Author(s):  
Anastasia Dmitrieva ◽  
Dyshlyuk Lubov ◽  
Fotina Natalia
Keyword(s):  
Ascorbic Acid ◽  
Human Body ◽  
The Body ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Ethanol Mixture ◽  
Industrial Enterprises ◽  
Promising Source ◽  
Active Substances ◽  
Selection Of

Global technological progress is one of the main problems of ecosystem deterioration. The high concentration of industrial enterprises contributes to the development of the region's environmental crisis and the decline in public health. An increase in the environmental pollutant contributes to the activation of oxidative stress in the human body, which plays a key role in the pathogenesis of a number of chronic diseases (cancer, diabetes, cardiovascular diseases, etc.), leading to a decrease in life expectancy and early aging of the body. To increase the adaptive abilities of the human body, it is important to use plant raw materials. A promising source of natural nutrients is the Hedysarum neglectum Ledeb. In order to obtain the extract of the forgotten kopek, the method of extraction was used at room temperature with a reverse refrigerator for 2 hours. In this study, to determine the working parameters of extraction (type of extractant, concentration of extractant), a selection of various extractive substances was selected. The efficiency of the extraction process was determined by two parameters: extractivity and yield of biologically active substances. The maximum extractivity was observed when using 50 % ethyl alcohol. To determine the working concentration of the water-ethanol mixture, the prepared extracts were analyzed for the content of flavonoids, tannins, and ascorbic acid. The maximum yield of biologically active substances (flavonoids 419.02±3.58 mg%, tannins 8.10±1.03 %, ascorbic acid 691.04±3.62 mg/kg) was observed during extraction with 50% water-ethanol mixture. The obtained results suggest that the water-ethanol extract of Hedysarum neglectum Ledeb. it is a potential source of natural biologically active substances for creating functional food products.

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