scholarly journals FREEZE-EXTRACTION TECHNOLOGIES FOR OBTAINING BIOLOGICALLY-ACTIVE SUBSTANCES OF PLANT ORIGIN

2018 ◽  
Vol 8 (4) ◽  
pp. 73-82
Author(s):  
V.N. Bekhterev ◽  
◽  
V.I. Malyarovskaya ◽  
Keyword(s):  
Biologically Active Substances ◽  
Biologically Active ◽  
Plant Origin ◽  
Active Substances

scholarly journals Study on domestic market of medicinal products of plant origin

2018 ◽  
pp. 30-36
Author(s):  
V. M. Minarchenko ◽  
A. Yu. Butko
Keyword(s):  
Medicinal Plants ◽  
Raw Materials ◽  
Domestic Market ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Herbal Remedies ◽  
Plant Origin ◽  
Resource Base ◽  
Natural Resource Base ◽  
Active Substances

The popularity of herbal remedies and medicines, with the participation of biologically active substances from plants is traditionally high. The annual increase of the domestic market for herbal remedies is due to the preservation and modernization of production capacities for processing of medicinal vegetative raw materials in Ukraine, introduction of modern scientific developments, a large natural resource base of medicinal plants and attracting investments in the development of this industry. The aim of our work was the study of the domestic market of medicines of plant origin, which includes herbal remedies, substances and preparations with the participation of biologically active substances from plants. The object of the study was domestic medicines of plant origin that are registered in Ukraine for 2012–2017. The study used the analytical, statistical methods, and the results of its own resource studies of medicinal plants. Phytopharmaceutical market of Ukraine is actively developing due to the attraction of new types of medicinal plants and expanding the range of medicines. The number of domestic drugs with the participation of biologically active substances from plants has increased by 17.4% compared with 2014. It is established that as of 1 January 2017 in Ukraine was 1 141 the form of medicinal drugs of plant origin. Of them: 645 – domestic products, 496 – foreign. Most of the herbal drugs in the pharmaceutical market of Ukraine are made from wild and cultivated domestic raw materials.

scholarly journals Development of methods for analysis of the amount of flavonoids and their stability study in the combined dental gel

2021 ◽  
pp. 3-10
Author(s):  
Yu. Maslii ◽  
A. Materiienko ◽  
O. Ruban ◽  
I. Bezruk ◽  
L. Ivanauskas
Keyword(s):  
Stability Study ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Plant Origin ◽  
Active Components ◽  
Drug Substances ◽  
The Stability ◽  
And Storage ◽  
Active Substances

An important aspect in the pharmaceutical development of dental medicines is to provide them with a prolonged therapeutic effect while reducing the side effects of drug substances and the possibility of long-term use. This can be achieved by using active components of plant origin. Aim. To develop methods for analyzing biologically active substances in the composition of a new combined dental gel. Materials and methods. The study object was a dental gel containing “Phytodent” complex tincture (PJSC “CPP Chervona zirka”, Ukraine). Based on the analysis of the composition of the tincture it was proposed to carry out standardization by the amount of biologically active substances, namely flavonoids. Identification was carried out by TLC, while the quantitative determination by absorption spectrophotometry, the ultraviolet and visible method by the reaction with aluminum chloride using the standard method calculated with reference to rutin and the absorbance measurement at 406 nm. Results and discussion. As a result of the research, the methods for the analysis of flavonoids in the composition of the new combined gel have been developed. The spectrophotometric method developed is characterized by specificity, accuracy, precision and linearity with r = 0.9998. One of the important issues when using components of plant origin is their stability both during preparation and storage. Using the method developed the stability of flavonoids has been studied depending on pH changes of the carbomer-based dental gel. Conclusions. It has been determined that the methods developed are easily reproducible and allow to identifying and quantifying flavonoids in the dental gel. It has been found that a stable content of flavonoids is characteristic of the carbomer-based gel neutralized to pH values from 5.0 to 6.0.

scholarly journals OBTAINING FLAVONOID FROM TARAXACUM KOK-SAGHYZ RODIN PLANT GROWING IN KAZAKHSTAN

2021 ◽  
Vol 2 (446) ◽  
pp. 155-160
Author(s):  
K.S. Smailova ◽  
G.E. Azimbaeva ◽  
A.A. Bakibaev ◽  
M.S. Abdikerim
Keyword(s):  
Melting Point ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Distilled Water ◽  
Herbal Preparation ◽  
Plant Origin ◽  
Aggregate State ◽  
Nmr Spectrum ◽  
Second Stage ◽  
Active Substances

In recent years, the interest of researchers in the herbal preparation has grown significantly. Plants are sources of biologically active substances (BAS). In previous articles, the chemical composition and biologically active substances of plants endemic Taraxacum kok-saghyz Rodin growing in Kazakhstan has been studied. Among the BAS of plant origin, inulin and flavonoids occupy a special place. The article examines the release of inulin and flavonoid from the stem of Taraxacum kok-saghyz Rodin plants. In order to isolate a flavonoid, you first need to extract inulin. Due to the fact that in our plants, inulin accumulates up to 40%. Therefore, the first stage was to isolate inulin: with extractions 1:10 with distilled water for 60 minutes, and in the second stage, the further isolation of the residue was first dried, the dry residue was 1:10 with a ratio of 70% ethanol for 3 hours. The inulin yield was -5%, the melting point was 1300C. A The yield of flavanoid is 0.66%, the melting point is 1700 C, the aggregate state is acicular light brown light. The structure of the isolated flavonoid was determined on a Uviline 9100 spectro-photometer; the highest absorption was observed at a wavelength of 364 nm. Consequently, the structure of the isolated flavonoid coincides with the literature data. The maxima of the UV, IR, 13С -NMR. spectrum show that flavonol is a derivative.

About the use of an iodine-containing vegetable ingredient in food products

2021 ◽  
pp. 12-14
Author(s):  
Елена Сергеевна Симоненко ◽  
Сергей Владимирович Симоненко ◽  
Александр Юрьевич Золотин ◽  
Маргарита Сергеевна Копытко ◽  
Любовь Карповна Пацюк
Keyword(s):  
Technological Process ◽  
Food Products ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Plant Origin ◽  
Technical Documentation ◽  
Critical Approach ◽  
Natural Form ◽  
Dry Extract ◽  
Active Substances

Перспективным направлением разработки пищевых продуктов, в том числе продуктов для детского питания, является использование в их составе природных ингредиентов растительного происхождения. Критический подход к подбору таких ингредиентов позволяет повысить ценность пищевого продукта, с одной стороны, за счет использования биологически активных веществ в их естественной форме, с другой - за счет существенного улучшения органолептических кондиций продукта. Проведенные исследования химического состава плодов фейхоа показали привлекательность их использования в качестве ингредиента растительного происхождения, который может позиционироваться как «источник органического йода», относящегося к дефицитным микроэлементам. Определены этапы и параметры технологического процесса получения компонента растительного происхождения - сухого экстракта плодов фейхоа. Разработана нормативная документация на сухой экстракт плодов фейхоа. Проведены исследования рецептур продуктов с компонентами растительного происхождения. Определены этапы и параметры технологического процесса производства продуктов с компонентами растительного происхождения. Разработан проект технологического регламента производства продуктов с растительными компонентами. Разрабатываемый продукт позиционируется как источник природной формы йода. Согласно технологической схеме выработки продукта, потери биологически активных веществ наиболее вероятны на стадии пастеризации, в связи с чем проведены исследования потерь биологически активных веществ, находящихся в составе экстрактов фейхоа, в процессе тепловой обработки. A promising area of development of food products, including products for baby food, is the use of natural ingredients of plant origin in their composition. A critical approach to the selection of such ingredients allows to increase the value of the food product, on the one hand, due to the use of biologically active substances in their natural form, on the other, due to a significant improvement in the organoleptic conditions of the product. Studies of the chemical composition of feijoa fruits have shown the attractiveness of their use as an ingredient of plant origin, which can be positioned as a «source of organic iodine» belonging to deficient micronutrients. Stages and parameters of technological process of obtaining component of plant origin - dry extract of feijoa fruits are determined. Regulatory and technical documentation for feijoa fruit dry extract has been developed. The preparations of products with components of vegetable origin were investigated. Stages and parameters of technological process of production of products with components of plant origin are defined. A draft technological regulation for the production of products with plant components has been developed. The product being developed is positioned as a source of natural iodine. According to the process scheme of the product production, losses of biologically active substances are most likely at the pasteurization stage, in connection with which studies of losses of biologically active substances in the composition of feijoa extracts during heat treatment were carried out.

Microscopic fungi of lithobiont communities of Argentine Islands Region: Data from the 22nd Ukrainian Antarctic Expedition

2020 ◽  
Vol 62 (1-2) ◽  
pp. 49-68
Author(s):  
T. O. Kondratiuk ◽  
T. V. Beregova ◽  
I. Yu. Parnikoza ◽  
S. Y. Kondratyuk ◽  
A. Thell
Keyword(s):  
Filamentous Fungi ◽  
Mucor Circinelloides ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Microscopic Fungi ◽  
Rhodotorula Rubra ◽  
Yeast Fungi ◽  
Antarctic Expedition ◽  
Geomyces Pannorum ◽  
Active Substances

The identification of the diversity of microscopic fungi of lithobiont communities of the Argentine Islands in specimens collected during the 22nd Ukrainian Antarctic Expedition was the purpose of this work. Samples of rock, soil, mosses and lichens of rock micro-habitats of “Crustose lichen sub-formation and fruticose lichen and moss cushion sub-formation” were used in the work. These samples were used for extracting and cultivation of filamentous fungi on dense nutrient media. Determination of physiological and biochemical characteristics and identification of yeast-like fungi were performed using a microbiological analyser ‘Vitek-2’ (‘Bio Merieux’, France). Cultivation of microorganisms was carried out at temperatures from +2 to +37 °C. In results cultures of microscopic fungi of Zygomycota (Mucor circinelloides), Ascomycota (species of the genera cf. Tlielebolus, Talaromyces), representatives of the Anamorphic fungi group (Geomyces pannorum, species of the genera Alternaria, Acremonium, Aspergillus, Penicillium, and Cladosporium) were isolated from Antarctic samples. Microscopic fungi Penicillium spp. were dominated after the frequency in the studied samples (54.5%). Rhodotorula rubra and Candida sp. among isolated yeast fungi, and dark pigmented fungi represented by Aureobasidium pulhdans and Exophiala spp. were identified. The biological properties of a number of isolated fungi (the potential ability to synthesise important biologically active substances: melanins, carotenoids, lipids) are characterised. Mycobiota of rock communities of Argentine Islands is rich on filamentous and yeast fungi similarly to other regions of Antarctica. A number of fungi investigated are potentially able to synthesise biologically active substances. The dark pigmented species of the genera Cladosporium, Exophiala, Aureobasidium pulhdans, capable of melanin synthesis; ‘red’ yeast Rhodotorula rubra (carotenoid producers and resistant to toxic metals); Mucor circinelloides and Geomyces pannorum, lipid producers, are among these fungi. Yeast-like fungi assimilated a wide range of carbohydrates, which will allow them to be further used for cultivation in laboratory and process conditions. The collection of technologically promising strains of microorganisms, part of the Culture Collection of Fungi at Taras Shevchenko National University of Kyiv (Ukraine), is updated with isolated species (strains) of filamentous fungi and yeast – potential producers of biologically active substances, obtained within this study.

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