scholarly journals Prescribing trend of antimalarial drugs at the Ghana Police Hospital

2015 ◽  
Vol 9 (04) ◽  
pp. 409-415 ◽  
Author(s):  
Daniel Kwame Afriyie ◽  
Seth Kwabena Amponsah ◽  
Robert Antwi ◽  
Stephen Yayra Nyoagbe ◽  
Kwasi Agyei Bugyei

Introduction: Malaria ranks among the top three leading causes of morbidity and mortality in developing countries. Appropriate use of recommended antimalarial drugs is vital in the effective management of malaria. Methodology: This study sought to assess the prescribing trend of antimalarial drugs at the Ghana Police Hospital. Antimalarial drug prescribing trends from 3,127 patient cards were assessed at the pharmacy unit of the hospital between December 2012 and May 2013 using modified World Health Organization rational drug prescribing indicators. Results: Of the 6,697 drugs assessed from the patient cards, antimalarial drugs prescribed included artemether-lumefantrine, 4,226 (63.1%), artemether injection with artemether-lumefantrine tablets, 1,741 (26%), artesunate injection, 241 (3.6%), artemether injection, 194 (2.9%), and artesunate-amodiaquine tablets, 188 (2.8%). The average number of drugs prescribed per encounter was 2.1. A total of 4,052 (60.5%) drugs were prescribed by their generic names, and 2,645 (39.5%) were prescribed by their brand names. There were 2,250 (33.6%) encounters with injection (33.6%), and 6,001 (89.6%) of the prescribed drugs were from the essential drugs list. Prescriptions conforming to recommended dosage regimen totaled 6,328 (94.5%). Conclusion: The antimalarial prescribing pattern at the hospital was generally satisfactory. However, the use of injectable antimalarials appeared to be high.

2018 ◽  
Vol 16 (3) ◽  
pp. 279-284
Author(s):  
Binaya Shrestha ◽  
Sanjaya Mani Dixit

Background: In order to promote rational drug use in developing countries, assessment of drug use pattern using the World Health Organization drug use indicators is important. The aim of this study was to assess the drug prescription patterns at Kathmandu Medical College Teaching Hospital, using some of the World Health Organization core drug use indicators.Methods: A prospective cross-sectional study was carried out in order to determine current prescribing trends at Kathmandu Medical College Teaching Hospital. A total of 605 prescriptions were collected and analyzed in the study.Results: The average number of drugs per prescription was 5.85 considering the total amount of prescriptions. Furthermore, assuming each prescription as an individual patient, 64.1% of patients received antibiotics, and 71% of patients received injectable form of drugs. Among antibiotics the most common antibiotics prescribed were Ceftriaxone, Amoxicillin/Cloxacillin, Azithromycin, Cefixime, and Cloxacillin. Only 16.94% of the medicines were prescribed in generic names with the rest 83.06% of the medicines being prescribed in brand names and 47.55% of medicines prescribed were from the National List of Essential Medicines-Nepal.Conclusions: The current study revealed that polypharmacy and prescription writing using brand names were common. Prescriptions writing in generic name needs to be promoted and encouraged. There appears to be a crucial need for the development of prescribing guidelines when it comes to antibiotics. Keywords: Drug prescription; drug utilization; prescribing practices; rational drug use; WHO prescribing indicators.


Author(s):  
Vinod S. Deshmukh ◽  
Swapnil P. Chube

Background: World Health Organization (WHO) has defined diarrhoea as, ‘the passage of loose stools by an individual, at least thrice a day or more frequently than normal’. It is most commonly caused by intestinal infection, mainly viral. Every year there are about 2 billion cases of diarrhoea worldwide, a second leading cause of mortality in children below the age of 5 years. WHO estimated that antibiotic treatment was necessary in only one in twenty cases of childhood diarrhoea. Yet huge resources are currently spent on anti-diarrhoeal drugs annually, most rendered useless or harmful. This study was proposed to evaluate the utilization pattern of drugs prescribed for diarrhoea in children, in a government tertiary care hospital in Maharashtra.Methods: This cross-sectional observational study was carried out in the paediatric ward of government tertiary care hospital, Maharashtra. All patients of age less than twelve years with diarrhoea admitted to paediatric ward within the study period of January 2015 - June 2016 were included in the study. Patients older than twelve years or admitted with other gastrointestinal diseases or co-mordbid conditions were excluded. Statistical analysis was done using descriptive statistics.Results: Majority of the patients admitted were males and more than half the patient population were in the age group of less than or equal to 3 years. Polypharmacy was found to be present in the prescribing pattern, with average, more than 4 drugs prescribed for diarrhoea treatment, in each prescription. Majority drugs were prescribed using brand names and parenteral route. Use of antibiotics was also found to be inappropriate in majority of the cases.Conclusions: The study highlighted the importance of drug utilisation studies and pointed out inappropriate drug prescribing trends for diarrhoea cases in a tertiary care hospital in Maharashtra.


Author(s):  
Eko Prasetio ◽  
Wahyu Utami ◽  
Zulhabri Othman ◽  
Ari Wardani ◽  
Abdul Rahem ◽  
...  

AbstractBackgroundThe Government of Indonesia has put in place many interventions for rationalizing drug use at all levels of the health services including in primary care centers (puskesmas). One of the programs for the rational use of drugs at the puskesmas is the monitoring and evaluation of drug use conducted by pharmacists. The purpose of this research was to evaluate the rationality of drug use in Pamekasan puskesmas that use World Health Organization (WHO) prescribing indicators and to find the difference in the percentage of rationality of drug use between puskesmas in Pamekasan.MethodsThis study reviewed official documents considering reporting of rational drug use. The documents were obtained from the district health office or from the public domain from 2014 to 2018. Data were then collated, extracted, and presented as frequencies.ResultsThe percentage prescribed for antibiotics for acute respiratory infection (ARI) non-pneumonia was 47.27% and percentage prescribing antibiotic drugs in a non-specific diarrhea was 59.85%. The percentage prescribed for injection was 36.15%. The average number of drugs prescribed per treatment was 2.61.ConclusionsThe majority of WHO guidelines stated that prescribing indicators were not met by the puskesmas in Pamekasan, except for the parameters for the average number of drugs prescribed per consultation. This shows an alarming clarion call for the local healthcare stakeholders to improve such situations.


Prescription is a written order and direction by a registered physician to the pharmacist for the particular use of a medicine product for a patient. The aim of the research was to observe the prescription pattern of doctors in their chamber practice according to the World Health Organization (WHO) prescribing indicators. A total of 300 prescriptions of outdoor patients from various departments of different private chambers of medical practitioners were collected from 1st August to 31st October 2019 and were evaluated. After evaluation and data analysis we got, patients’ age and gender were not mentioned in 6% prescriptions. Dose and course of treatment were incomplete in 60%, 72%, and 52% of prescriptions respectively. Abbreviations were used in 100% prescriptions. Doctor’s medical registration number was mentioned in 13% prescriptions only. A total of 1042 drugs was prescribed in 300 prescriptions. The average number of drugs prescribed was 3.38±1.79 (Mean±SD). Most of the prescriptions contained a brand name (93.33%) of the drugs whereas only a few (6.7%) used the generic names (P<0.05). Antibiotics and injections were ordained in 64% and 8% cases respectively. Approximately 60% of drugs were prescribed according to the Essential Medicine List (EML) of Bangladesh. Our study has shown that very few physicians are acquainted and follow the WHO standard of prescribing which can lead to seriously negative health consequences. Moreover, the presence of antibiotics in two-third of all prescriptions should ring an alarm to prevent its aberrant use.


2021 ◽  
Vol 71 (4) ◽  
pp. 1243-47
Author(s):  
Saman Omer ◽  
Bushra Tayyaba Khan ◽  
Omer Jalil

Objective: To evaluate prescribing practices in public health facilities of district Mirpur, Kashmir where no previous evidence regarding drug-prescribing behaviours was available. Study Design: Cross-sectional study. Place and Duration of Study: Department of Pharmacology and Therapeutics, Army Medical College, Rawalpindi and outpatient departments of public health facilities in district Mirpur, Kashmir, from Aug to Oct 2020. Methodology: The prescribing pattern analysis was done by objective observations of prescriptions after patient-physician encounter. World health organization defined core and complementary prescribing indicators were evaluated for all the prescriptions. Results: Among the core prescribing indicator, average number of medicines per prescription were 3.11 (World Health Organization’s standard, 1.6-1.8). Only 2% and 67% of medicines were generic and essential medicines respectively (standard, 100%). Almost half the prescriptions contained antibiotics (standard, 20-26.8%) whereas 8% had injections (standard, 13.4- 24.1%). Among the complementary indicators there was no prescription without medicines and average prescription cost was 479 Pakistani Rupees. Conclusion: This is the first study to give a snapshot of prescribing behaviours in public health facilities in Kashmir. All the prescribing indicators except injectables were below the standards. A multi-disciplinary approach involving authorities, industry and professionals is required to promote rational prescribing.


2020 ◽  
Vol V (I) ◽  
pp. 17-24
Author(s):  
Aimen Qaiser ◽  
Zahra Hassan Kiani ◽  
Farina Abid ◽  
Tania Pervaiz ◽  
Zafar Iqbal

Promotion of rational use of drugs in developing countries is necessary for improving the quality of life. Therefore, evaluation of drug use pattern using World Health Organization (WHO) indicators is necessary for assessment of rational use of drugs. 200 prescriptions were randomly collected from different pharmacies in Mirpur and evaluated to measure prescribing indicators. Data was analyzed using SPSS (version 25). Average count of drugs prescribed per prescription was 3.8 (S.D+ 2.01). Percentage of antibiotics prescribed, and injections prescribed per prescription was 42% (n=84) and 16% (n=32) respectively. The percentage of drugs prescribed from Essential Drugs List was 90.5%. It was concluded that prescribing pattern was far away from the standard WHO requirements. Greater number of drugs and overuse of antibiotics focused on close monitoring and regulation of prescribing pattern. Steps should be taken to encourage the rational use of drugs to improve the quality of life.


Author(s):  
R. SENTHILSELVI ◽  
M. BOOPANA ◽  
Linta Sathyan ◽  
PRIYA VISUVASAM ◽  
V. GANESAN

Objective: The study was carried out to generate research on drug utilization pattern in paediatric patients in government headquarters hospital, Tiruppur, Tamilnadu, India using world health organization (WHO) and international network for rational use of drugs (INRUD) core indicator. Methods: The core prescribing indicators of the world health organization was used to assess the appropriate use of drugs. Index of rational drug prescribing (IRDP) developed by Zhang and Zhi was also used to find out the performance of a health care system in terms of drug utilization. Results: Out of 859 drugs in 200 cases the highest prescribed drug class is antibiotics 304(35.39%) and the majority of drugs were administered in injectable form 412(47.94%). It was analysed that a majority of prescriptions 117(58.5%) were discharged in between 4-7 d. 161(80.5%) patients were dismissed after completion of treatment. On analysing world health organization (WHO) prescribing core indicators, the average number of drugs per prescription was 4.29 which is higher than double the average number (i.e., 2). This indicates poly-pharmacy practice. 97.78% of drugs were prescribed were the generic name and percentage of encounters with antibiotic prescribed was 90.5% which is thrice greater than world health organization (WHO) standard<30%. Prescribing of injections is not within the world health organization (WHO) recommended range<20% and it was far higher showing 97.5% which is essential for paediatric inpatients. The prescribing practice in paediatric ward is in complete adherence to national essential drug list (EDL) or formulary. The mean value of the index of rational drug prescribing (IRDP) obtained was 3.09 which is very similar to that of optimal value world health organization (WHO). Conclusion: Prescription by generic name, prescribing drugs from essential drug list (EDL) and free government supply are encouraging findings in this hospital. The result shows poly-pharmacy and overuse of antibiotics are the areas to be concerned. The better clinical outcome shows rational prescribing is practised well.


2020 ◽  
Vol 11 (3) ◽  
pp. 3119-3126
Author(s):  
Nabeel Siddique ◽  
Azhar Hussain ◽  
Madeeha Malik

Failure to adopt the rational pattern of prescribing and dispensing by health professionals represents a significant risk to the safety of patient and lead to pharmaceuticals wastage. This study was designed to evaluate the prescribing and dispensing pattern at the selected basic healthcare facilities of Islamabad Pakistan. World Health Organization with collaboration to International Network for the Rational Use of Drugs has provided the core indicators to configure and examine the prescribing patterns. The study was conducted in 2018, using these indicators following the study sites, fourteen Basic Health Units, three Rural Health Centres and three local dispensaries located in Islamabad (Pakistan) were randomly visited and that accounts overall 600 prescribing episodes collected retrospectively. The results of this study highlighted that the average number of drugs prescribed was 2.751. Percentage of drugs prescribed by generic was 41.15%. Percentage of steroids, injections and antibiotics were 7.68%, 16.05% and 48.6%. The drugs prescribed from Essential Drug List were 75.08%. Average consultation time was 2.699 minutes. The average dispensing time was 1.479 minutes. We concluded that high number of average drugs per prescription, over prescription of antibiotics, low generic prescribing, less average consultation and dispensing time found in healthcare facilities. Keywords: Prescribing pattern, Basic health facilities, INRUD prescribing indicators, WHO prescribing indicators


2021 ◽  
Vol 19 (1) ◽  
pp. 29-44
Author(s):  
SAMI MUSTAFA ALSHAKHSHIR ◽  
SYED AZHAR SYED SULAIMAN ◽  
MAHMOUD SADI ALHADDAD ◽  
MOHD PAZUDIN

The aim of this study is to assess the rational prescribing pattern of drugs for pregnant women using World Health Organization (WHO)/International Network for Rational Use of Drugs (INRUD) core drug prescribing indicators. A one-year retrospective research design from (October 2016–September 2017) was used to review pregnant women prescriptions from their medical records at Hospital Universiti Sains Malaysia (HUSM). A structured data collection form using WHO/INRUD document on prescribing indicators was used. Data was sorted and categorised according to the US Food and Drug Administration (USFDA) pregnancy classification systems and Anatomical Therapeutic Classification (ATC). Then, data was compared with the references values of WHO/INRUD. Descriptive analysis were performed using SPSS version 20. A total of 741 medical files met the study inclusion criteria. The average number of prescribed drugs per prescription and the percentage of prescribed drugs from hospital formulary list and health ministry list were within the acceptable range listed by WHO. Whereas, the percentage of pregnant women with antibiotics and injection drugs were lower than normal values 17.67% and 8.23%, respectively. Percentage of prescribed drugs from categories C and D were 13.8% and 2.8%, respectively. Whereas 24.8% of prescribed drugs were from unclassified risk category. On the other hand, multivitamins preparations were the highest category of prescriptions 17.7%. Injections and number of antibiotics per encounter were lower than the recommended range listed by WHO. However, a great caution and careful prescribing behaviour of physicians were noticed at gynaecology/obstetric departments and most of the prescribed medications were rational and safe during pregnancy.


Pharmacy ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 113
Author(s):  
Oumar Bassoum ◽  
Mouhamadou Faly Ba ◽  
Ndèye Marème Sougou ◽  
Djibril Fall ◽  
Adama Faye

Introduction: Data on drug use in paediatrics are scarce in Senegal. The objective of this study was to assess the prescribing indicators in a paediatric population seen in an outpatient consultation at a Health Centre in Dakar, Senegal. Methods: A retrospective and analytical study was conducted. The study population consisted of prescriptions for children aged 0 to 14 years who were seen in ambulatory consultation between 1 June and 30 November 2019. The sample size was 600 prescriptions. The systematic survey was then conducted. Five prescription indicators recommended by the World Health Organization were calculated. The R software was used for descriptive analysis, bivariate analysis and binomial logistic regression. Results: The average number of drugs per prescription was 2.56. The proportion of drugs prescribed under the International Nonproprietary Name (INN) was 18.9%, while the proportion of drugs on the National Essential Medicines List (NEML) was 41.3%. The proportions of prescriptions with at least one antibiotic and one injectable product were 41.5% and 1.3%, respectively. Conclusions: This study showed that prescribing habits were inadequate. Thus, it would be necessary to move towards continuing training of prescribers in the wise use of medicines.


Sign in / Sign up

Export Citation Format

Share Document