scholarly journals Impact of Anemia in Pregnant Women on the Neonatal Conditions

2021 ◽  
Vol 9 (B) ◽  
pp. 1185-1188
Author(s):  
Raisa Aringazina ◽  
Gulnara Kurmanalina ◽  
Yerlan Bazargaliyev ◽  
Victoria Kononets ◽  
Bakhtiyar Kurmanalin ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Weight Ratio ◽  
Deficiency Anemia ◽  
Control Group ◽  
The World ◽  
Anemia During Pregnancy ◽  
Group 2 ◽  
Anemia Group

Background. One of the most prevalent illnesses in the world is anemia. Anemia in pregnant women has been a pressing obstetric issue for many years and is one of the most common complications of pregnancy in the world, particularly in developing countries. Aim. To study the condition of neonates born to women with anemia during pregnancy. Methods. A retrospective analysis of 230 patients' medical records in maternity and pregnancy pathology departments. The patients were divided into 2 groups: Group 1 consisted of patients suffering from iron deficiency anemia, Group 2 comprised patients without iron deficiency anemia. Results. The height-to-weight ratio in the group of neonates born to mothers with anemia statistically was significantly lower compared to the control group. The proportion of neonates with hypotrophy in the group born to mothers with anemia statistically was significantly higher. Body length and birth condition indices assessed according to the APGAR scale were virtually identical across the groups. Conclusions. Anemia during pregnancy affects the trophism of a fetus, which is largely reflected in the health of neonates. Treating maternal anemia is important to prevent or decrease the incidence of underweight in infants at birth.

scholarly journals The Effect of Iron Deficiency Anemia Early in the Third Trimester on Small for Gestational Age and Birth Weight: A Retrospective Cohort Study on Iron Deficiency Anemia and Fetal Weight

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Ilknur Col Madendag ◽  
Mefkure Eraslan Sahin ◽  
Yusuf Madendag ◽  
Erdem Sahin ◽  
Mustafa Bertan Demir ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Fetal Weight ◽  
Deficiency Anemia ◽  
Control Group ◽  
Third Trimester ◽  
Mild Anemia ◽  
Moderate Anemia ◽  
Anemia Group

Aim. The aim of the present study was to evaluate the relationship between iron deficiency anemia and small for gestational age (SGA) in early third trimester pregnancies. Methods. A total of 4800 pregnant women who met the inclusion criteria were analyzed retrospectively. We included pregnant women who had iron deficiency anemia between 26+0 and 30+0 weeks of gestation and delivered singletons between 37+0 and 41+6 weeks of gestation. Patients were divided into four groups according to anemia level: (1) hemoglobin (Hb) < 7 mg/dl (n = 80), (2) Hb 7–9.9 mg/dl (n = 320), (3) Hb 10–10.9 mg/dl (n = 1300), and (4) Hb > 11 mg/dl (n = 3100, control group). The primary outcome of this study was the presence of SGA. Results. The demographic and obstetric characteristics were similar among all the groups. Maternal age, BMI <30 kg/m2, nulliparity rates, and previous cesarean delivery rates were similar among groups. Ethnicity was significantly different in the severe and moderate anemia groups (<0.001). Mean fetal weight was 2900 ± 80 g in the severe anemia group, 3050 ± 100 g in the moderate anemia group, 3350 ± 310 g in the mild anemia group, and 3400 ± 310 g in the control group. Fetal weight was significantly lower in the severe and moderate anemia groups compared to the mild anemia and control groups (<0.001). The SGA rate was 18.7% in the severe anemia group, 12.1% in the moderate anemia group, 5.3% in the mild anemia group, and 4.9% in the control group. SGA was significantly higher in the severe and moderate anemia groups compared to the mild anemia and control groups (<0.001). Conclusion. The results of this study indicated that early third trimester severe and moderate iron deficiency anemia was associated with SGA. Iron deficiency anemia in pregnant women may lead to low birth weight.

scholarly journals The impact of iron deficiency correction in pregnant women on the perinatal period and children’s health status

2020 ◽  
Vol 65 (1) ◽  
pp. 51-58 ◽  
Author(s):  
E. A. Balashova ◽  
L. I. Mazur ◽  
Yu. V. Tezikov ◽  
I. S. Lipatov
Keyword(s):  
Health Status ◽  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Perinatal Period ◽  
Full Term ◽  
Deficiency Anemia ◽  
Anemia During Pregnancy ◽  
Anemia Group ◽  
Group 1

Purpose. To identify the effects of gestational iron deficiency anemia after treatment with iron-containing drugs  during the perinatal period on the health status of full-term children during their 1st year of life.Patients and methods.The authors carried out a prospective observational cohort study of full-term infants of I & II health group from their birth to twelve months. The course of pregnancy and labor was analyzed retrospectively. Hemoglobin, serum ferritin and C-reactive protein were measured in the six and twelve months old children and their mothers in 6 months after giving birth. We examined 140 couples of mother-child with gestational anemia (Group 1) and 166 couples without anemia during pregnancy (Group 2) in 6 months after giving birth, and in 12 months – 103 and 131 couples respectively. All women with iron deficiency anemia (Group 1) received therapy during pregnancy. Results. Gestational anemia is associated with threatened miscarriage (Odds Ratio (OR) 3.496; 95% CI 2.013–6.072), chronic placental insufficiency (OR 1.907; 95% CI 1.025–3.548), delivery by cesarean section (OR 2.729; 95% CI 1.651–4.502), increased infectious morbidity in pregnant women (OR 1.079; 95% CI 1.025–3.548) and insufficient lactation (OR 1.990; 95% CI 1.209– 3.277). Treated anemia during pregnancy is not associated with low birth weight and low weight of 6 and 12 months old children. 8.6% of 6 months old children suffered from iron deficiency anemia, which is two times lower than in the group without anemia (p=0.007). The frequency of iron deficiency anemia did not differ in 12 months old children (р=0.543). Conclusion: Iron supplementation reduces the negative impact of anemia on child’s health, including anthropometric indicators, iron stores, and risk of infectious diseases. The indirect effect is maintained through the adverse course of the perinatal period and the low duration of lactation. 

scholarly journals A study for efficacy and safety of ferric carboxymaltose versus iron sucrose in iron deficiency anemia among pregnant women in tertiary care hospital

2019 ◽  
Vol 8 (6) ◽  
pp. 2280
Author(s):  
Divyani Agrawal ◽  
Deepa Lokwani Masand
Keyword(s):  
Iron Deficiency ◽  
Adverse Events ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Intravenous Iron ◽  
Iron Sucrose ◽  
Deficiency Anemia ◽  
Ferric Carboxymaltose ◽  
Efficacy And Safety ◽  
Anemia During Pregnancy

Background: Anemia is one of the common manageable problem among the pregnant women worldwide, which contributes to maternal and perinatal mortality. This study aims to compare the efficacy and safety of intravenous ferric carboxymaltose with intravenous iron sucrose in treating anemia during pregnancy. Objective of this study was to compare safety and efficacy of intravenous ferric carboxymaltose with intravenous ferric sucrose in iron deficiency anemia during pregnancy.Methods: It’s an interventional prospective study conducted in Department of Obstetrics and Gynecology at NIMS, Jaipur, Rajasthan, India constituting of 100 pregnant women. Group 1- 50 pregnant women were treated with intravenous ferric carboxymaltose and Group 2: 50 pregnant women were treated with intravenous iron sucrose. Hemoglobin and serum ferritin levels were measured pre and post treatment with parenteral iron therapy. The efficacy of intravenous ferric carboxymaltose in comparison to intravenous iron sucrose was assessed. The evaluation of safety and tolerance with the parenteral therapy was also performed.Results: Anemia during pregnancy was more prevalent among the reproductive age group and in multiparous women. The mean rise in the hemoglobin level with ferric carboxymaltose was 2.92 gm/dl and with that of iron, sucrose was 1.08 gm/dl. The man rise in the serum ferritin levels with ferric carboxymaltose was 64.97ng/ml and with iron sucrose was 31.64 ng/ml. Ferric carboxymaltose was observed to be safer with no adverse events in comparison to the Iron sucrose which was related with adverse events among 03 pregnant women.Conclusions: Intravenous ferric carboxymaltose was more efficacious and safer in comparison to intravenous iron sucrose among pregnant women. Hence, ferric carboxymaltose is the drug of choice in treatment of iron deficiency anemia during pregnancy.

Investigation of ischemia modified albumin levels in iron deficiency anemia

2017 ◽  
Vol 42 (3) ◽  
Author(s):  
Sibel Bilgili ◽  
Giray Bozkaya ◽  
Funda Kırtay Tütüncüler ◽  
Murat Akşit ◽  
Mehmet Yavuz
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Iron Supplementation ◽  
Binding Capacity ◽  
Oral Iron ◽  
Deficiency Anemia ◽  
Control Group ◽  
Ischemia Modified Albumin ◽  
Before And After ◽  
Anemia Group

AbstractObjective:The aim of this study was to evaluate the levels of ischemia-modified albumin (IMA), before and after oral iron supplementation in iron deficiency anemia and to determine the correlations between IMA and hemoglobin values.Study design:IMA, hemoglobin, hematocrit, mean corpuscular volume, ferritin, iron, total iron binding capacity and albumin levels were measured in 140 female patients with newly established as iron deficiency anemia before and after treatment and in 84 female healthy controls.Results:IMA levels were higher in the anemia group [0.340±0.082 absorbance units (ABSU)] compared to control group (0.291±0.077 ABSU). After oral iron therapy we saw that IMA values (0.392±0.080 ABSU) were higher than the IMA levels of the anemia group and the control group (p<0.05). Only in the anemia group there were negative correlations between IMA and hemoglobin, hematocrit.Conclusion:We conclude that the high levels of IMA in the anemia group might be attributed to hypoxia due to low hemoglobin levels. Iron is an oxidant element and oral iron supplementation may be associated with oxidative stress and may increase IMA levels by changing the albumin molecule. We thought that, IMA can be demonstrative of the severity of anemia since it was correlated with hemoglobin in the anemia group.

scholarly journals The importance of RET-He in the diagnosis of iron deficiency and iron deficiency anemia and the evaluation of response to oral iron therapy

2019 ◽  
Vol 38 (4) ◽  
pp. 496-502
Author(s):  
Mehmet Ali Uçar ◽  
Mesude Falay ◽  
Simten Dağdas ◽  
Funda Ceran ◽  
Selin Merih Urlu ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Oral Iron ◽  
Deficiency Anemia ◽  
Control Group ◽  
Iron Treatment ◽  
Research Population ◽  
Group A ◽  
Iron Parameters ◽  
Anemia Group

SummaryBackgroundThe purpose of this study is to investigate whether or not reticulocyte hemoglobin equivalent (RET-He) is a superior indicator of blood count and other iron parameters in terms of diagnosing iron deficiency (ID) and iron deficiency anemia (IDA), and thus evaluating a patient’s response to oral iron treatment.MethodsThe research population consisted of 217 participants in total: 54 control, 53 ID, 58 non-ID anemia, and 52 IDA patients. A hemoglobin (Hb) value of < 130.0 g/L was defined as indicating anemia for men, while an Hb value of < 120.0 g/L was defined as indicating anemia for women. All patients were administered 270 mg oral elemental iron sulphate daily.ResultsThe RET-He was significantly lower in the IDA group, compared to other groups (IDA: 21.0 ± 4.1, ID: 26.0 ± 4.9, non-ID anemia: 32.1 ± 6.8, control: 36.6 ± 7.0; < 0.001). The ID group had a lower RET-He compared to the non-ID anemia group and the control group. On the 5th day of treatment, the ID and IDA group showed no significant differences in terms of Hb while the RET-He level demonstrated a significant increase. The increase in the RET-He level observed in the IDA group on the 5th day was significantly higher compared to the increase observed in the ID group. A RET-He value of 25.4 pg and below predicted ID diagnosis with 90.4% sensitivity and 49.1% specificity in IDA patients, compared to the ID group.ConclusionsThe results of our study, therefore, suggest that RET-He may be a clinically useful marker in the diagnosis of ID and IDA.

scholarly journals The role of erythropoietin in the pathogenesis and treatment of iron deficiency anemia during pregnancy and in the postpartum period

2003 ◽  
Vol 52 (4) ◽  
pp. 17-22
Author(s):  
Eduard K. Ailamazyan ◽  
М. A. Tarasova ◽  
А. А. Zaitsev ◽  
А. V. Samarina
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Postpartum Period ◽  
Pathological Condition ◽  
The Body ◽  
Deficiency Anemia ◽  
Fetoplacental Complex ◽  
Iron Deficient ◽  
Anemia During Pregnancy

Iron deficiency anemia (IDA) is a very common pathological condition during pregnancy and the postpartum period. In the structure of hematological diseases in pregnant women, anemias account for about 90% and in most cases are iron deficient [3, 17, 19]. In the third trimester of pregnancy and in the early postpartum period, almost every woman has a latent iron deficiency, and 3040% develop IDA [4, 15, 16, 20, 26]. According to the Ministry of Health of the Russian Federation, the frequency of IDA in Russia has increased 6.3 times over the past ten years, and in St. Petersburg - almost 2 times. The development of anemia during pregnancy is due to an imbalance of iron in the body and is associated with its increased costs for creating a fetoplacental complex, an increase in iron metabolism and a redistribution of this trace element in favor of the fetus. Iron deficiency in the body of pregnant women and women in childbirth is associated with inadequate replacement of losses due to alimentary and mobilized iron.

scholarly journals ANEMIC PATIENTS

2015 ◽  
Vol 22 (12) ◽  
pp. 1550-1554
Author(s):  
Tayyaba Majeed ◽  
Rabia Adnan ◽  
Zahid Mahmood ◽  
Ishrat Majeed ◽  
Kanwal Saba ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Preterm Labor ◽  
Deficiency Anemia ◽  
Control Group ◽  
P Value ◽  
Increased Risk ◽  
Study Setting ◽  
Control Study

Pregnant women are particularly considered to be the most vulnerable groupbecause of the additional demands that are made on maternal stores during pregnancy. Theiron deficiency anemia is the most common nutritional deficiency problems in females and isresponsible of high maternal death rate in our society. Objectives: To determine the relationshipof frequency and severity of iron deficiency anemia to preterm labor and eventual perinatalout come in anemic patients. Study Design: It was a case control study. Study Setting: InObstetrics and Gynecology Unit-III, Sir Ganga Ram hospital, Lahore from July 2012 to June2013. Methodology: The study was conducted on 200 patients (100 cases and 100 controls)were studied. Cases were patients admitted in labor room with preterm labor and Controlswere females in labor at term at. Convenience sampling was done. On admission relevanthistory taking examination and investigation were done. The data was collected on a Performa.Results: There were 50 patients with anemia amongst the patients with preterm labor. In thecontrol group, 40 patients were suffering from anemia. In the patients with preterm labor themean hemoglobin was 9.83 grams/deciliter. In the control group the mean hemoglobin was10.3gm/dl. (Pregnant women having hemoglobin <10gm/dl are considered to be anemic). Theodds ratio was calculated to be 3.4 and P value was <0.05. Conclusions: Iron deficiencyanemia was associated with increased risk for low birth weight, preterm delivery, and perinatalmortality. The frequency of iron-deficiency anemia was seen in both groups of pregnant women.

scholarly journals Association between Serum Ferritin and Pre-eclampsia

2019 ◽  
Vol 47 (3) ◽  
pp. 18-24
Author(s):  
Ratna Paul ◽  
Mst Sabrina Moonajilin ◽  
Sujit Kumar Sarker ◽  
Himel Paul ◽  
Swapna Pal ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Serum Ferritin ◽  
Serum Ferritin Level ◽  
Ferritin Level ◽  
Deficiency Anemia ◽  
Control Group ◽  
The Mean

Pre-eclampsia (PE) is a major cause of maternal and prenatal morbidity and mortality in developing countries. PE occurs in about 6% of the general women population. It complicates about 5-15% of pregnancies over 20 weeks and is responsible for 16% of maternal mortality. Pre-delivery serum Ferritin concentration was significantly higher in patients with eclampsia than in healthy pregnant women. The serum ferritin was the best sensitive marker of the iron status parameters reflecting the preeclampsia. The aim of the study is to explore the association between serum ferritin and Preeclampsia and to do a comparison of serum ferritin to assess risk of development preeclampsia between case and control.This is a case-control study with laboratory methods. The study was carried out in Sir Salimullah Medical College and Hospital. Serum Ferritin was tested in the department of biochemistry, Bangabandhu Sheikh Mujib Medical University (BSMMU). The study was carried out from January 2008 to December 2009 and the sample size was 80. A total of 80 pregnant women, comprising of 40 PE and 40 normotensive primi or multigravida in the third trimester were enrolled in the study. The mean Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) were significantly higher in PE group on both occasions compared to normotensive women with similar chronological age gestational age. Out of the 40 cases 65% patients had severe proteinuria (+++) and 17.5% had moderate proteinuria (++) and 17.5% had mild proteinuria. The difference between case and control with respect to proteinuria was highly significant. More than two third (67.5%) of the cases did not have any iron deficiency anemia, while the rest (32.5%) had mild iron deficiency anemia. In the present study, the mean serum Ferritin level of PE group was almost 10 times higher (167.11 ± 10.43 ngm/ml) than that of controls (17.0 ± 3.03 ngm/ml) than that of control (431.0 ± 10.93 gm/dl). More than one-third of the cases showed serum ferritin >210 ngm/ml, compared to none of the control group. Serum Ferritin level is significantly higher in preeclamptic patients than the control group. Bangladesh Med J. 2018 Jan; 47 (3): 18-24

Effect of Multigrain Supplement on Improving Haemoglobin Level among Anemic Pregnant Women of Below Poverty Line

2020 ◽  
Vol 57 (1) ◽  
pp. 43
Author(s):  
Archana Prabhat ◽  
Meghana .
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
First Trimester ◽  
Poverty Line ◽  
Deficiency Anemia ◽  
Global Public Health ◽  
Lethal Complications ◽  
Anemia During Pregnancy ◽  
Public Health Challenge

<p>Anemia during pregnancy is a global public health challenge facing the world today. It is one of the potentially lethal complications of pregnancy leading to large number of maternal and foetal losses but it is preventable and curable. The study was aimed to screen and identify the pregnant women of first trimester (10-12 weeks) who are having iron deficiency anemia and to evaluate the effectiveness of multigrain supplement (malt powder) among the pregnant women with iron deficiency anemia in improving the level of haemoglobin. This descriptive study was conducted among pregnant women of age group (18-30 years) residing in rural place Kanamadagu of Kudligi taluk. Sixety of them were randomly selected based on Haemoglobin (Hb) level &lt;10 gm/dL and interviewed with help of self-structured questionnaire tool. Collected data was analyzed for descriptive and inferential statistics. The overall prevalence of anemia was found to be 99.5% and about three fourth of subjects were falling within the mild (10-11 gm/dL) category of anemia. Most significant raise in Hb level found to be in 4<sup>th</sup> week compared to intermediated weeks of malt consumption. Use of multigrain supplement was found to be the most effective way to overcome anemia i.e. from mild to normal range Hb level.</p>

scholarly journals A PROSPECTIVE STUDY ON RISK FACTORS OF IRON DEFICIENCY ANEMIA IN PREGNANT WOMEN AND THEIR MANAGEMENT

2020 ◽  
pp. 50-55
Author(s):  
R. DINESH KUMAR ◽  
M. BOOPATHI RAJA ◽  
SREEVEENA P. S. ◽  
RACHEL ANN MATHEW
Keyword(s):  
Risk Factors ◽  
Iron Deficiency ◽  
Prospective Study ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
Full Detail ◽  
The World ◽  
Moderate Anemia ◽  
A Prospective Study

Objective: Iron deficiency anemia during pregnancy leads to preterm birth, low birth weight and increases the incidence of postpartum hemorrhage (PPH) and the reason for the incidence of PPH is higher in India compared with the rest of the world. In this study, our main goal was to find out the risk factors and complications of iron deficiency anemia and their management in pregnant women. Methods: It is a prospective study done at Obstetrics and Gynecology Department in Government District Headquarters Hospital, Tiruppur. All subjects were analyzed in full detail and hemoglobin estimation was also done to the patients. Results: Study found that 52% shows moderate anemia followed by 30% mild and 18% severe, respectively. Risk factors are found in 55% cases. Study found an association between risk factors and severity of anemia. Conclusion: Iron deficiency anemia continues to be the commonest etiology of anemia in pregnancy. The prevalence of iron deficiency in a pregnant woman is amongst the highest in the world. Untreated iron deficiency has significant adverse feto-maternal consequences. Iron supplementation and antenatal care are the basic requirements to prevent anemia.

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