Infants of Hypothyroid Mothers at Risk of Developing Hypothyroidism: A Cross-sectional Study in Qassim Region of Saudi Arabia

Introduction Hypothyroidism is one of the most prevalent endocrine disorders in women of childbearing age. If it goes untreated, can seriously affect maternal and fetal outcomes.Aim This study aimed to assess the prevalence of hypothyroidism in infants born to hypothyroid mothers and to analyze associated fetal complications.Subjects and methods This is a quantitative cross-sectional study conducted among pregnant mothers at Al Qassim region, Saudi Arabia. Data of pregnant women with clinical hypothyroidism during the last five years 2015-2019 were obtained from visiting records of Endocrine Clinic in Qassim University. These participants were contacted and written informed consents were obtained from the participants after a brief introduction of the study. A comprehensive survey questionnaire was used to collect information about demographic and study variables. Results 153 mothers were enrolled. The most common age group was 31 – 45 years with mostly Saudis (93.5%). Complications during pregnancy were detected among 47.1% of mothers. The most common complication during pregnancy was C-section (26.8%). The prevalence of infants with hypothyroidism was 2.6% while the prevalence of newborn babies with temporary/permanent hypothyroidism was 4.6%. Decreased activity (7.8%) and an increased in weight (5.2%) were the most common symptoms of a child at the time of diagnosis.Conclusion Infants with hypothyroidism were not widely prevalent in this study. Cesarean delivery, gestational diabetes and anemia were some of the most common maternal complications during pregnancy.Keywords

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Folate deficiency knowledge and use of folic acid among women of childbearing age in the Kingdom of Saudi Arabia: A population-based cross-sectional study

International Journal of Medicine in Developing Countries ◽

10.24911/ijmdc.51-1542585084 ◽

2019 ◽

pp. 60-66

Author(s):

Amira Nemri ◽

Shahd Aslany ◽

Orjwan Abulaban ◽

Ghaidaa Sindi ◽

Shahad Zuhairy ◽

...

Keyword(s):

Saudi Arabia ◽

Folic Acid ◽

Folate Deficiency ◽

Population Based ◽

Cross Sectional Study ◽

Women Of Childbearing Age ◽

Sectional Study ◽

Childbearing Age ◽

Kingdom Of Saudi Arabia ◽

Cross Sectional

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Community Pharmacists’ Practice, Awareness, and Beliefs about Drug Disposal in Saudi Arabia

Healthcare ◽

10.3390/healthcare9070823 ◽

2021 ◽

Vol 9 (7) ◽

pp. 823

Author(s):

Sultan Alghadeer ◽

Mohammed N. Al-Arifi

Keyword(s):

Saudi Arabia ◽

Community Pharmacists ◽

Cross Sectional Study ◽

Environmental Damage ◽

Community Pharmacies ◽

Age Group ◽

Sectional Study ◽

Cross Sectional ◽

Take Back ◽

Medication Disposal

The awareness among Saudi people regarding the good and safe practice of drug disposal is fairly low. Community pharmacists’ potential toward drugs disposal directions and practice are not emphasized enough. Therefore, a cross sectional study was conducted in Riyadh, Saudi Arabia, to evaluate the practice, awareness and beliefs of community pharmacists about disposal of unused drugs. Out of 360 subjects who participated in the study, more than 70% returned the unused drugs to the pharmaceutical distributors. Around 80% of the participants confirmed the risk of environmental damage due to the inappropriate disposal of drugs, and 87.5% of them held themselves responsible for preventing such risk. Approximately 85% of surveyed pharmacists believed community pharmacies to be an appropriate location for the collection of unused drugs. There was no significant association between the community pharmacists’ age group and years of practice as community pharmacists with either the awareness of unused medication disposal on environmental hazards, or the beliefs about the appropriate location for collecting unused drugs (p > 0.05). The awareness and proactive accountable responsibility, along with community pharmacists’ belief of appointing pharmacies to collect unused drugs, strongly support the institution of drug take-back programs.

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Pregnancy protection and pregnancies in women prescribed ACE inhibitors or ARBs: a cross-sectional study in primary care

British Journal of General Practice ◽

10.3399/bjgp20x712997 ◽

2020 ◽

Vol 70 (700) ◽

pp. e778-e784

Author(s):

Elizabeth Lovegrove ◽

John Robson ◽

Patricia McGettigan

Keyword(s):

Primary Care ◽

Ace Inhibitors ◽

Ace Inhibitor ◽

Angiotensin Receptor Blockers ◽

Age Groups ◽

Cross Sectional Study ◽

Women Of Childbearing Age ◽

Sectional Study ◽

Childbearing Age ◽

Cross Sectional

BackgroundThe teratogenic risks of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are well documented, but prescribing these in younger women in primary care is becoming increasingly frequent.AimTo record how frequently women of childbearing age, who are prescribed an ACE inhibitor or ARB, receive preconception advice and/or are prescribed contraception, and how many pregnancies, terminations, and miscarriages occur in this population. Additionally, to ascertain whether patterns in the above differ across age groups.Design and settingCross-sectional study conducted among patients from 141 general practices in East London.MethodWomen aged 15–45 years who were issued a prescription for an ACE inhibitor or ARB between 1 October 2018 and 1 January 2019 inclusive were included. An electronic search strategy was designed to extract pseudonymised data concerning preconception and contraception advice, contraception, and pregnancies from the electronic clinical system; this was applied to the selected cohort on 1 January 2019. Data were analysed in 5-year age groups.ResultsOf 302 939 women aged 15–45 years, 2651 (0.9%) were prescribed an ACE inhibitor or an ARB in a 3-month period. Of these, 2159 (81.4%) had no advice and no contraception prescription recorded, 35 (1.3%) had preconception advice recorded, and 230 (8.7%) had contraception advice recorded. A total of 100 pregnancies and 21 terminations/miscarriages were recorded in the 12 months preceding the index date (1 January 2019).ConclusionThis study found that the recording of pre-pregnancy advice and contraception in women of childbearing age who were prescribed an ACE inhibitor or an ARB was suboptimal; this may place women and their babies at risk of exposure to teratogens during pregnancy. The findings indicate that there is a need for improved safety strategies based in primary care.

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Recent trends in seroprevalence of rubella in Korean women of childbearing age: a cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2019-030873 ◽

2020 ◽

Vol 10 (1) ◽

pp. e030873 ◽

Cited By ~ 1

Author(s):

Rihwa Choi ◽

Yejin Oh ◽

Youngju Oh ◽

Sung Ho Kim ◽

Sang Gon Lee ◽

...

Keyword(s):

Cross Sectional Study ◽

Korean Women ◽

Test Results ◽

Women Of Childbearing Age ◽

Sectional Study ◽

Childbearing Age ◽

Igg Antibody ◽

Cross Sectional ◽

Specific Igg ◽

Catch Up

ObjectivesThe aim of this study was to investigate the immunity against rubella using the serological status of rubella-specific IgG antibodies (antirubella IgG) in Korean women of childbearing age (15–49 years).DesignRetrospective cross-sectional study.SettingPopulation-based cross-sectional study in South Korea.ParticipantsBetween January 2010 and December 2017, test results from Korean women aged 15–49 years who had visited an obstetric private clinic (nationwide institutions) and had requested rubella-specific IgG antibody tests from Green Cross Laboratories were obtained from the laboratory information system.ResultsBetween 2010 and 2017, antirubella IgG test results from 328 426 Korean women aged 15–49 years who had visited private obstetric clinics (1438 institutions nationwide) were retrospectively analysed by tested year, age, cohort and geographic regions. Over the 8-year study period, the rate of unimmunised women ranged from 7.8% to 9.7%. Multivariable-adjusted logistic regression models showed that the odds of being immune to rubella (positive and equivocal results of antirubella IgG test) were lower in 2017 compared with 2010, in women in their 40s, in a pre-catch-up cohort and in women living in Incheon, Busan, South Gyeongsang, North and South Jeolla and Jeju provinces (p<0.0001).ConclusionsIn consideration of the factors associated with prevalence of women unimmunised to rubella, future public health efforts should be focused on catch-up activities. The results of this study could be used to strengthen disease control and prevent rubella, including a nationwide immunisation programme.

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Serum Folate Shows an Inverse Association with Blood Pressure in a Cohort of Chinese Women of Childbearing Age: A Cross-Sectional Study

PLoS ONE ◽

10.1371/journal.pone.0155801 ◽

2016 ◽

Vol 11 (5) ◽

pp. e0155801 ◽

Cited By ~ 2

Author(s):

Minxue Shen ◽

Hongzhuan Tan ◽

Shujin Zhou ◽

Ravi Retnakaran ◽

Graeme N. Smith ◽

...

Keyword(s):

Blood Pressure ◽

Chinese Women ◽

Cross Sectional Study ◽

Serum Folate ◽

Inverse Association ◽

Women Of Childbearing Age ◽

Sectional Study ◽

Childbearing Age ◽

Cross Sectional

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Keracunan Pestisida dan Hipotiroidisme pada Wanita Usia Subur di Daerah Pertanian

Kesmas National Public Health Journal ◽

10.21109/kesmas.v4i5.172 ◽

2010 ◽

Vol 4 (5) ◽

pp. 217

Author(s):

Suhartono Suhartono ◽

Dharminto Dharminto

Keyword(s):

Cross Sectional Study ◽

Pesticide Poisoning ◽

Women Of Childbearing Age ◽

Sectional Study ◽

Childbearing Age ◽

Cross Sectional ◽

Pesticides Exposure ◽

Agricultural Areas ◽

Childbearing Women ◽

Range Of Values

Wanita bermukim di daerah pertanian berisiko terpajan pestisida yang dapat berakibat hipotiroidisme yang pada kehamilan dapat menyebabkan gangguan tumbuh-kembang janin. Tujuan penelitian ini adalah mengetahui angka kejadian keracunan pestisida dan hipotiroidisme pada wanita usia subur di daerah pertanian. Penelitian ini menggunakan disain penelitian cross-sectional dan 26 WUS terpilih sebagai subjek secara acak. Semua subjek dilakukan pengukurankadar TSH, fT4 dan enzim kolinesterase, sementara kadar T3, UEI, dan Pb darah diukur pada sub-sampel. Penderita dinyatakan keracunan pestisida apabila ditemukan kadar enzim kolinesterase <3,9 μg/L dan dinyatakan hipotiroidisme apabila kadar TSH >4,5 μIU/L. Penelitian ini menemukan rerata kadar kolinesterase adalah 7,26 (±1,28) dengan kisaran nilai 5,33-9,39 μg/L; rerata kadar TSH adalah 5,09 (±6,14), dengan kisaran nilai 0,47-31,73μIU/L; rerata kadar fT4 adalah 15,18 (±2,09), dengan kisaran nilai 8,73-18,87 pmol/L; rerata kadar T3 adalah 1,75 (±0,51), dengan kisaran nilai 1,24-2,95 pmol/L. Prevalensi keracunan pestisida pada WUS 0,0% dan prevalensi hipotiroidisme 46,2%.Kata kunci : Pestisida, hipotiroidisme, wanita usia subur, daerah pertanianAbstractWomen lived in agricultural areas are risk to suffer various disorders due to pesticides exposure such as hypothyroidism. Hypothyroidism causes growth and development disorders of fetus. The aim of the study is to find out the prevalence of pesticide poisoning and hypothyroidism in women of childbearing age in agricultural areas. Cross-sectional study was conducted and 26 women of childbearing age were selected randomly. TSH, fT4 and cholinesterase enzymelevels were measured in all subjects, while levels of T3, UEI and blood Pb were measured in the sub-sample. Pesticide poisoning is determined if the levels of enzymes cholinesterase <3.9 μg/L and determined as hypothyroidism if the TSH >4.5 μIU/L. This study showed that mean of cholinesterase levels was 7.26 (± 1.28), range of values 5.33-9.39 μg/L; mean of TSH levels was 5.09 (± 6.14), range of values 0.47-31.73 μIU/L; mean of fT4 level was 15.18 (±2.09), range of values 8.73-18.87 pmol/L; mean of T3 levels was 1.75 (±0.51), range of values 1.24-2.95 pmol/L. The prevalence of pesticide poisoning in childbearing women was 0.0% and prevalence of hypothyroidism was 46.2%.Key words : Pesticide, hypothyroidism, women of childbearing age, agricultural area

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Knowledge, Attitudes, and Practices towards Diabetic Retinopathy among Primary Care Physicians of Saudi Arabia: A Multicenter Cross-Sectional Study

Healthcare ◽

10.3390/healthcare9121697 ◽

2021 ◽

Vol 9 (12) ◽

pp. 1697

Author(s):

Ashokkumar Thirunavukkarasu ◽

Abdulmohsen Khaled Almulhim ◽

Faisal Ahmed Albalawi ◽

Ziyad Muharib Alruwaili ◽

Ola Ali Almajed ◽

...

Keyword(s):

Primary Care ◽

Saudi Arabia ◽

Diabetic Retinopathy ◽

Work Experience ◽

Primary Care Physicians ◽

Cross Sectional Study ◽

Age Group ◽

Sectional Study ◽

Cross Sectional ◽

Attitudes And Practices

Primary care physicians play a vital role in preventing the progression of diabetic retinopathy (DR) from the initial stages to the late stages. This questionnaire-based analytical cross-sectional study was carried out to assess the knowledge, attitude, practices, and their correlation among 274 randomly selected primary care physicians in Saudi Arabia. Among the studied population, high knowledge, attitudes, and practice scores were observed in 21.5%, 15%, and 29.2% of the physicians, respectively. The mean knowledge score was significantly higher among the age group of less than 30 years (p = 0.031) and the female gender (p = 0.012). The attitude scores were significantly higher among the Saudi physicians (p = 0.027) and those with PHC work experience of less than five years (p < 0.001). Regarding the practices, a significant association was found among the age group of less than 30 years (p = 0.019) and Saudi physicians (p = 0.003). There was a significant positive correlation between knowledge (correlation coefficient (r) = 0.739, p < 0.001) and attitude (r = 0.479, p = 0.007) with the practice scores. It is recommended that targeted continuous medical education, workshops, and seminars are conducted on the prevention and care of DR among primary care physicians. Furthermore, an exploratory multicenter study that involves primary care physicians belonging to all ministries and private sectors is warranted.

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