Lipid profile and C-reactive protein changes to elastic-band resistance training in young healthy men

2021 ◽  
pp. 1-8
Author(s):  
F. Kalvandi ◽  
R. Azizbeigi ◽  
K. Azizbeigi

Resistance bands are a device for resistance training routine or rehabilitation program and come in various sizes, lengths, and strengths. The purpose of this study was to investigate the effect of elastic resistance training (ERT) on lipid profiles and C-reactive protein (CRP) changes in young and healthy men. Twenty untrained young and healthy men voluntarily participated in the study and were randomly assigned to the ERT (n=10) and control group (n=10). The ERT group performed three non-consecutive sessions per week for eight weeks. Blood was sampled before training and this was repeated after 72 h of the interval of the last session of ERT. The concentration of CRP and lipid profiles, including changes of high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), and total cholesterol (TC), were measured. Also, changes in body fat percentage (BF%) were measured. It was observed that CRP was not significantly affected by ERT (P>0.05). Also, TC and TG did not change significantly due to ERT (P>0.05). However, ERT increased the HDL-C concentration (P=0.001) and significantly decreased LDL-C (P=0.033). It is concluded that although the elastic resistance training failed to improve CRP; however, with a positive impact on some of the lipid profiles and health indices, it can be a useful, simple and low-cost exercise training in health promotion.

2005 ◽  
Vol 62 (11) ◽  
pp. 811-819
Author(s):  
Aleksandra Jovelic ◽  
Goran Radjen ◽  
Stojan Jovelic ◽  
Marica Markovic

Background/Aim. C-reactive protein is an independent predictor of the risk of cardiovascular events and diabetes mellitus in apparently healthy men. The relationship between C-reactive protein and the features of metabolic syndrome has not been fully elucidated. To assess the cross-sectional relationship between C-reactive protein and the features of metabolic syndrome in healthy people. Methods. We studied 161 military pilots (agee, 40?6 years) free of cardiovascular disease, diabetes mellitus and active inflammation on their regular annual medical control. Age, total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol, triglycerides, fasting glucose, glycosylated hemoglobin, blood pressure, smoking habit, waist circumference and body mass index were evaluated. Plasma C-reactive protein was measured by the immunonephelometry (Dade Behring) method. Metabolic syndrome was defined according to the National Cholesterol Education Program Expert Panel. Results. The mean C-reactive protein concentrations in the subjects grouped according to the presence of 0, 1, 2 and 3 or more features of the metabolic syndrome were 1.11, 1.89, 1.72 and 2.22 mg/L, respectively (p = 0.023) with a statistically, significant difference between those with 3, and without metabolic syndrome (p = 0.01). In the simple regression analyses C-reactive protein did not correlate with the total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol, body mass index and blood pressure (p > 0.05). In the multiple regression analysis, waist circumference (? = 0.411, p = 0.000), triglycerides to high density lipoprotein cholesterol ratio (? = 0.774, p = 0.000), smoking habit (? = 0.236, p = 0.003) and triglycerides (? = 0.471, p = 0.027) were independent predictors of C-reactive protein. Conclusions. Our results suggested a cross-sectional independent correlation between the examined cardiovascular risk factors as the predominant features of metabolic syndrome and C-reactive protein in the group of apparently healthy subjects. The lack of correlation of C-reactive protein with the total cholesterol and low density lipoprotein cholesterol in our study may suggest their different role in the process of atherosclerosis and the possibility to determine C-reactive protein in order to identify high-risk subjects not identified with cholesterol screening.


2020 ◽  
Vol 36 (7) ◽  
pp. 477-486
Author(s):  
Wale Johnson Adeyemi ◽  
Tahir Ahmad Abdussalam ◽  
Amin Abdulrahim ◽  
Luqman Aribidesi Olayaki

Melatonin (Mel) is known to prevent and mitigate lead (Pb)-induced gonadotoxicity. However, there is no report in literature on the endogenous levels of different biomarkers after the cessation of Pb exposure, with or without treatment with Mel. Fifty adult male Wistar rats were divided into five groups ( N = 10), which included control ((vehicle (normal saline) - treated) − 0.1 ml/day); lead chloride (PbCl2) untreated (3 weeks vehicle + 3 weeks Pb); Pb recovery (3 weeks Pb + 3 weeks vehicle); Pb + Mel (3 weeks Pb + 3 weeks Mel); and Mel (3 weeks vehicle + 3 weeks Mel) groups. Pb and Mel were administered at 50 and 10 mg/kg B.W. ( p.o.), respectively. The results showed that Pb caused significant decreases in total bilirubin (TB), phospholipids (PLP), superoxide dismutase (SOD), catalase (CAT), and total antioxidant capacity (TAC), but significant elevations in alkaline phosphatase (ALP), aspartate aminotransferase (AST), triglyceride (TG), and malondialdehyde (MDA). Although the adverse effects of Pb on TB, ALP, AST, SOD, MDA, and TAC were sustained after the cessation of exposure, a reversal was observed in total cholesterol (TC), TG, PLP, CAT, and c-reactive protein (CRP) results. Nevertheless, the detrimental effects of Pb on alanine aminotransferase (ALT), albumin, and globulin were only expressed post-exposure. Treatment with Mel caused no significant effect on TB and albumin levels. However, unlike TAC and CRP, the hormone significantly reduced ALP, AST, ALT, TC, low-density lipoprotein cholesterol, PLP, SOD, CAT, MDA, and globulin to levels comparable to the control group. In conclusion, following the cessation of Pb exposure, alterations in physiological balance could be elevated, sustained, or reversible. However, Mel enhanced the reestablishment homeostatic status after Pb administration.


2016 ◽  
Vol 23 (6) ◽  
pp. 792-801 ◽  
Author(s):  
Shreya Mukhopadhyay ◽  
Kelly Fellows ◽  
Richard W Browne ◽  
Prachi Khare ◽  
Sandhya Krishnan Radhakrishnan ◽  
...  

Purpose: To investigate levels of oxysterols in healthy control (HC) and multiple sclerosis (MS) patients and their interdependence with demographic, clinical characteristics, and cholesterol biomarkers. Methods: This study included 550 subjects (203 HC, 221 relapsing–remitting MS (RR-MS), 126 progressive MS (P-MS)). A complete lipid profile including total cholesterol (TC); high-density lipoprotein–cholesterol (HDL-C); low-density lipoprotein–cholesterol (LDL-C); apolipoproteins (Apo) A1, A2, B, and E; C-reactive protein (CRP); 24-hydroxycholesterol (HC); 25-HC; 27-HC; 7α-HC; and 7-ketocholesterol (KC) was obtained. Lipoprotein particle sizing by proton nuclear magnetic resonance (H1 NMR) was available for 432 subjects. Results: The levels of 24-HC, 27-HC, and 7α-HC (all p < 0.015) were lower in MS compared to HC, and 7-KC was higher in P-MS compared to RR-MS ( p < 0.001). TC, LDL-C, and ApoB were associated with higher levels of all oxysterols (all p < 0.05) in HC. In MS, LDL-C was associated with higher levels of 24-HC, 25-HC, 7-KC, and 7α-HC (all p < 0.05), while TC and ApoB were associated with increased levels of all oxysterols (all p < 0.005). Conclusion: The findings of lower 24-HC, 27-HC, and 7α-HC in MS compared to HC and higher 7-KC in P-MS compared to RR-MS indicate that the oxysterol network is disrupted in MS.


2021 ◽  
Vol 28 (4) ◽  
pp. 3-9
Author(s):  
Keyvan Hejazi ◽  
Mehrdad Fathi ◽  
Mahsa Salkhord ◽  
Maryam Dastani

Abstract Introduction. Inflammatory and coagulation factors are among the various factors that are involved in the development of cardiovascular diseases. The aim of this study was to evaluate the effect of eight weeks of combined training (endurance-intermittent resistance and endurance-continuous resistance) on coagulation, fibrinolytic and lipid profiles of overweight women. Material and Methods. This was a quasi-experimental study of 36 overweight women, who were divided into three groups of endurance-intermittent resistance training (n = 12), endurance-continuous resistance training (n = 12) and control (n = 12). The training was performed during eight weeks, three times a week, and each session lasted for 80 to 90 minutes. Blood samples were analyzed for the concentrations of coagulation, fibrinolytic and lipid profiles before and after the completion of the training program. Results. Fibrinogen levels, prothrombin time (PT), partial thromboplastin time (PTT) and platelet count decreased significantly at the end of the training in both intervention groups. However, serum levels of D-dimer increased significantly in both training groups. Also, the levels of triglycerides (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) decreased significantly, while the levels of high-density lipoprotein cholesterol (HDL-C) increased significantly. Conclusions. Combined exercise improved most coagulation factors and lipid profiles at the end of the training period. Therefore, the results of our research suggest that a combined exercise program can improve the health of overweight women.


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Brandon Stuwart Shaw ◽  
Stacey Turner ◽  
Ina Shaw

Background: Cardiovascular disease (CVD) exemplifies a major medical problem as it is the most considerable cause of morbidity and mortality. While sport conditioning specialists understand and differentiate the different benefits of resistance training (RT) subtypes on athletic performance, this distinction is less clear for health professionals when designing CVD risk reduction programs. Objectives: This study attempted to investigate and compare the effects of hypertrophy and muscular endurance RT on CVD risk in sedentary males. Methods: Sedentary male smokers were randomly assigned to either an eight-week hypertrophy RT group (HTG) (n = 15), muscular endurance RT groups (METG) (n = 15), or a non-exercising control group (CON) (n = 15) to assess their impact on smoking, blood pressure, cholesterol, and cardiorespiratory fitness (VO2max) variables associated with the four most prominent CVD risk factors. Data were analyzed using SPSS-25 software using a paired sample t-test and ANOVA. Results: Significant (P ≤ 0.05) improvements were found in three of the 15 measured variables in the HTG (resting mean arterial pressure (RMAP) (P = 0.024); total cholesterol (TC): HDL-C ratio (P = 0.009), and HDL-C: low-density lipoprotein cholesterol (LDL-C) ratio (P = 0.038), with a deleterious decrease in high-density lipoprotein cholesterol (HDL-C) (P = 0.027). In turn, significant improvements were found in the METG in 10 of the 15 measured variables, namely; cigarettes smoked per day (P = 0.037), resting systolic blood pressure (RSBP) (P = 0.002), resting diastolic blood pressure (RDBP) (P = 0.006), RMAP (P = 0.000), TC (P = 0.010), triglycerides (TG) (P = 0.010), LDL-C (P = 0.007), HDL-C: LDL-C (P = 0.018), non-HDL-C (n-HDL-C) (P = 0.010), and VO2max (P = 0.001), and a deleterious decrease in HDL-C (P = 0.026). Conclusions: While the oversimplification of RT design for CVD reduction has resulted in cardio-centric CVD training programs, this study demonstrates that some subtypes of RT (i.e. muscular endurance training) may prove more useful than others in reducing multiple CVD risk factors simultaneously.


2010 ◽  
Vol 16 (1) ◽  
pp. 67-72
Author(s):  
Chieh Chung LIU ◽  
Jui Kun CHUANG ◽  
Chun Hong LIN ◽  
Pu Hsi TSAI ◽  
Jun Yen LEE ◽  
...  

LANGUAGE NOTE | Document text in Chinese; abstract also in English. The objective of this study was to determine the effects on plasma lipoproteins, inflammation response and tissue-­damage markers level during their recovery following exhaustive run. These biochemical concentrations were measured before 30 min, immediately after, and 30 min, 1hr, 2hr, 24hr, 48hr, 72hr after an exhaustive run on treadmill in 15 health male subjects with 80%VO2max intensity. The result of one-way ANOVA with measure repeated analysis indicated that there were no significant changes in low-density lipoprotein cholesterol post run, and high-density lipoprotein cholesterol level was remain significant elevated (by 18%) until 2hr post run. The inflammatory marker of C-reactive protein level was significant elevated (by 42%) immediately and returned to baseline post 0.5hr. The neutrophils ratio remain significant increased (by 51%) during 0.5hr until 2hr and returned to baseline post 24hr. The tissue-damage markers were remain elevated by 23% immediately until 2hr in lactate dehydrogenase and only reach to peak (by 108%) significantly post 24hr in creatine kinase. It is concluded that an exhaustive exercise could induce the delay-onset damage and transient inflammatory response in tissue, and have enough rest or suitable antioxidant supplements for recovery. 目的:本研究旨在探討單次衰竭運動後恢復期對於血脂蛋白濃度變化與發炎損傷指標之影響。方法:受試者為15名健康男性(年齡22.8 ± 0.89歲,體重67. ± 1.81公斤),以高強度(80%VO2max)的固定負荷運動至衰竭,並於運動前30分鐘、運動後立即、0.5hr、lhr、2hr、24hr、48hr、72hr等時間點靜脈採血進行生化值分析。結果:以單因子相依樣本變異數分析顯示,低密度脂蛋白膽固醇(low density lipoprotein-cholesterol, LDL-C)在運動後均無明顯變化;而高密度脂蛋白膽固醇(high den­sity lipoprotein-cholesterol, HDL-C)則在衰竭運動後2hr明顯持續增加約18.3% (p < .05);發炎指標:C-反應蛋白(C-reactive protein, CRP)於衰竭後立即顯著上升約42%,隨即0.5hr後恢復。嗜中性球比例(neutrophils, net-s%)在運動後0.5hr至2hr持續增加約51%,於24hr之後恢復。組織損傷情形,乳酸脱氫酶(lactate dehydrogenase, LDH)活性在衰竭後立即至2hr期間顯著增加約23%,而肌酸激酶(creatine kinase, CK)活性則在24hr後才明顯增加約108%的峰值反應。結論:本研究血脂蛋白與發炎、損傷等生化反應結果,意味著單次衰竭運動後可能誘發體內組織的延遲性損傷與組織的短暫發炎反應,需要有足夠的休息時間或運用適當的抗氧化增補劑來進行運動恢復。


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