Cross Sectional Evaluation of Thyroid Hormone Levels in Non-diabetic and Diabetic Patients in Bangladeshi Population

2013 ◽  
Vol 6 (4) ◽  
pp. 228-233 ◽  
Author(s):  
Md. Jahangir Alam ◽  
Most. Nur-E-Taj Mokarrama ◽  
Md. Mominul Hoque ◽  
Md. Intaz Ali ◽  
Md. Mostafa Kamal ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Hormone Levels ◽  
Thyroid Hormone Levels ◽  
Bangladeshi Population

scholarly journals Thyroid hormone levels are associated with metabolic components: a cross-sectional study

2020 ◽  
Vol 61 (3) ◽  
pp. 230-238
Author(s):  
Ante Punda ◽  
Veselin Škrabić ◽  
Vesela Torlak ◽  
Ivana Gunjača ◽  
Vesna Boraska ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hormone Levels ◽  
Thyroid Hormone Levels

Abstract P266: Prevalence and Risk Factors of Thyroid Dysfunction in Older Adults in the Community

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Nermin Diab ◽  
Natalie Daya ◽  
Stephen P Juraschek ◽  
Seth Martin ◽  
John W McEvoy ◽  
...  
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Cardiovascular Risk ◽  
Thyroid Hormone ◽  
Thyroid Dysfunction ◽  
Thyroid Peroxidase ◽  
Age Group ◽  
Cross Sectional ◽  
Hormone Levels ◽  
Thyroid Hormone Levels

Context: Prevalence estimates and evidence informing treatment targets for thyroid dysfunction largely come from studies of middle-aged adults. There are limited data on the prevalence of thyroid dysfunction in older populations. Objective: To determine the prevalence of thyroid dysfunction and risk factors for abnormal thyroid tests in older adults. Methods: We conducted a cross-sectional analysis of data from participants aged 65 or older in the Atherosclerosis Risk in Communities (ARIC) study who attended visit 5 in 2011-2013. We measured serum concentrations of triiodothyronine (T3), free thyroxine (FT4), thyroid peroxidase antibody (Anti-TPO), and thyroid stimulating hormone (TSH) in 5,392 participants. We used multivariable linear and logistic regression to assess associations of demographic and clinical risk factors with thyroid hormone levels. Results: In this population of older adults (mean age 76; 56% women and 22% black), the prevalence of thyroid dysfunction was up to 25% when accounting for treated and untreated thyroid dysfunction categories. 15.6% reported use of medication for thyroid dysfunction. Among those not being treated, the prevalence of overt chemical hypothyroidism was 6.0% and subclinical hypothyroidism was 0.82%. Overt chemical hyperthyroidism and subclinical hyperthyroidism affected 0.26% and 0.78% of the population, respectively. Multivariable adjusted cardiovascular risk factor associations for TSH, FT4 and T3 levels are presented in Table . Men were less likely to be anti-TPO positive compared to women (OR=0.59, CI: 0.47,0.75, P<0.001). Conclusions: There is a high prevalence of thyroid dysfunction in this older, community-based population. Prevalence of thyroid dysfunction and thyroid hormone levels vary with sex, race, age group and multiple cardiovascular risk factors. Accounting for these associations in the clinical setting might prove useful in improving thyroid function assessment in this age group.

scholarly journals Assessment of Thyroid Hormone Levels in Diabetes Mellitus Subjects Resident in Port Harcourt Metropolis

2021 ◽  
pp. 40-46
Author(s):  
T. Neebee–Sordum ◽  
D. G. Tamuno-emine ◽  
D. Onwuli
Keyword(s):  
Diabetes Mellitus ◽  
Thyroid Hormone ◽  
Cross Sectional Study ◽  
Thyroid Stimulating Hormone ◽  
University Teaching ◽  
Cross Sectional ◽  
Hormone Levels ◽  
Port Harcourt ◽  
Thyroid Hormone Levels ◽  
Rivers State

Aim: The aim of this study was to assess thyroid hormone levels in among diabetics in Port- Harcourt  of Rivers State in Nigeria Study Design: This study is a cross-sectional study. Place and Duration of Study: This study was conducted at Chemical Pathology Department, Rivers State University Teaching Hospital, Port Harcourt, Nigeria, between December, 2019 and February, 2020. Methodology: A total of 224 subjects were recruited for the study, diabetic parents (132 subjects), non-diabetic parents (112 subjects. Five (5) ml of blood sample was collected and used to analyse for serum thyroxine (T4), tri-iodothyronine (T­­3) and thyroid stimulating hormone (TSH) using Enzyme-linked immunoasorbent assay. Data were analyzed statistically with SPSS version 22.0 and values considered significant at p< 0.05. Results: The mean ± S.D of serum TSH were 1.28± 0.6u/ml (control) and 1.84±1.05 u/ml (subject), (p=0.023). T4 value were 2.49 ± 0.86u/ml (control) (p=0.024) and 3.90 ±1,62u/ml (subjects) and T3 values were 1.89±0.41u/ml (p=0.0001). Conclusion: The evaluation of thyroid hormones (TSH, T4 and T3) among diabetes with the age ranges of population studied shows that there was altered thyroid hormone in diabetes mellitus individuals.

scholarly journals Clinical Associations of Thyroid Hormone Levels with the Risk of Atherosclerosis in Euthyroid Type 2 Diabetic Patients in Central China

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Limin Wang ◽  
Tingting Chen ◽  
Jiawei Yu ◽  
Huijuan Yuan ◽  
Xinru Deng ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Thyroid Hormones ◽  
Smoking Status ◽  
Central China ◽  
Diabetic Patients ◽  
Free Triiodothyronine ◽  
Type 2 Diabetic Patients ◽  
Hormone Levels ◽  
Thyroid Hormone Levels

Background. Thyroid function is associated with the etiology and pathogenesis of type 2 diabetes (T2D) and potentially contributes to the development of the complications of T2D. The association of thyroid hormones with atherosclerosis in euthyroid T2D patients is not clear. Purpose. To investigate the association of thyroid hormone levels with the risk of developing atherosclerosis in euthyroid T2D patients in Central China. Methods. This cross-sectional study recruited 910 euthyroid T2D patients from Henan Provincial People’s Hospital, China. Association among hemoglobin A1c (HbA1c), thyroid hormones, and the prevalence of atherosclerosis was assessed by multivariable Cox models after adjusting for covariates including age, BMI, duration of T2D, smoking status, SBP, TC, family history of T2D, and medications on hyperlipidemia. Results. Among all 910 subjects, 373 were diagnosed with atherosclerosis. There were 523 females and 387 males included in this study. The mean age was 51.9 years. The average BMI was 25.3 kg/m2. Low-normal serum-free triiodothyronine (FT3) levels (3.50–4.17 pmol/L) were associated with a high prevalence of atherosclerosis. Comparing with low-normal FT3, the prevalence ratio in patients with mid- (4.17–4.83 pmol/L) and high-normal FT3 level (4.83–6.50 pmol/L) is 0.74 (95% CI 0.56 to 0.97, p=0.029) and 0.63 (95% CI 0.46 to 0.87, p=0.005) after adjusting for covariates. High level of free thyroxine (FT4) also had decreased risk for atherosclerosis. Thyroid-stimulating hormone (TSH) and FT3 to FT4 ratio did not show significant association with the development of atherosclerosis. Conclusion. T2D patients with low but clinically normal FT3 level are more likely to develop macrovascular complications comparing with those with mid- and high-normal FT3 level.

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