scholarly journals Low-carbohydrate, high-protein diets for management of type 2 diabetes

2013 ◽  
Vol 98 (1) ◽  
pp. 247-248 ◽  
Author(s):  
Roman Pawlak
Keyword(s):  
Type 2 Diabetes ◽  
High Protein ◽  
Low Carbohydrate ◽  
High Protein Diets ◽  
Protein Diets

scholarly journals Effects of high-protein diets on body weight, glycaemic control, blood lipids and blood pressure in type 2 diabetes: meta-analysis of randomised controlled trials

2013 ◽  
Vol 110 (5) ◽  
pp. 781-789 ◽  
Author(s):  
Jia-Yi Dong ◽  
Zeng-Li Zhang ◽  
Pei-Yu Wang ◽  
Li-Qiang Qin
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Weight Loss ◽  
Body Weight ◽  
Meta Analysis ◽  
High Protein ◽  
Cochrane Library ◽  
High Protein Diets ◽  
Protein Diets

High-protein diets are popular for weight management, but the health effects of such diets in diabetic persons are inconclusive. The aim of the present meta-analysis was to examine the effects of high-protein diets on body weight and metabolic risk factors in patients with type 2 diabetes. We searched the PubMed and Cochrane Library databases for relevant randomised trials up to August 2012. Either a fixed- or a random-effects model was used to combine the net changes in each outcome from baseline to the end of the intervention. Overall, nine trials including a total of 418 diabetic patients met our inclusion criteria. The study duration ranged from 4 to 24 weeks. The actual intake of dietary protein ranged from 25 to 32 % of total energy in the intervention groups and from 15 to 20 % in the control groups. Compared with the control diets, high-protein diets resulted in more weight loss (pooled mean difference: − 2·08, 95 % CI − 3·25, − 0·90 kg). High-protein diets significantly decreased glycated Hb A1C (HbA1C) levels by 0·52 (95 % CI − 0·90, − 0·14) %, but did not affect the fasting blood glucose levels. There were no differences in lipid profiles. The pooled net changes in systolic and diastolic blood pressure were − 3·13 (95 % CI − 6·58, 0·32) mmHg and − 1·86 (95 % CI − 4·26, 0·56) mmHg, respectively. However, two studies reported a large influence on weight loss and HbA1C levels, respectively. In summary, high-protein diets (within 6 months) may have some beneficial effects on weight loss, HbA1C levels and blood pressure in patients with type 2 diabetes. However, further investigations are still required to draw a conclusion.

High protein diets and renal disease – is there a relationship in people with type 2 diabetes?

2013 ◽  
Vol 13 (5-6) ◽  
pp. 238-243 ◽  
Author(s):  
Amber Parry-Strong ◽  
Murray Leikis ◽  
Jeremy D Krebs
Keyword(s):  
Type 2 Diabetes ◽  
Renal Disease ◽  
High Protein ◽  
High Protein Diets ◽  
Protein Diets

Use of low carbohydrate, high protein diets in cats with diabetes mellitus

2008 ◽  
Vol 92 (2) ◽  
pp. 219-220 ◽  
Author(s):  
T. C. Hall ◽  
O. M. Mahony ◽  
L. M. Freeman ◽  
E. A. Rozanski
Keyword(s):  
Diabetes Mellitus ◽  
High Protein ◽  
Low Carbohydrate ◽  
High Protein Diets ◽  
Protein Diets

Decreased Warfarin Effect after Initiation of High-Protein, Low-Carbohydrate Diets

2005 ◽  
Vol 39 (4) ◽  
pp. 744-747 ◽  
Author(s):  
Stuart J Beatty ◽  
Bella H Mehta ◽  
Jennifer L Rodis
Keyword(s):  
Serum Albumin ◽  
Warfarin Therapy ◽  
Anticoagulation Therapy ◽  
Warfarin Dose ◽  
High Protein ◽  
Carbohydrate Diet ◽  
Low Carbohydrate Diet ◽  
Low Carbohydrate ◽  
High Protein Diets ◽  
Protein Diets

OBJECTIVE: To report 2 cases of decreased international normalized ratio (INR) after initiation of a high-protein, low-carbohydrate diet. CASE SUMMARIES: Case 1. A 67-year-old white woman had been receiving warfarin for 3 years for venous thromboembolism. After initiation of a high-protein, low-carbohydrate diet, the patient required a 22.2% increase (from 45 to 57.5 mg/wk) in warfarin dose. Her INR remained in the therapeutic range on this dose for 8 weeks. When the patient stopped the high-protein, low-carbohydrate diet, a decrease back to the original warfarin dose was required to return to a therapeutic INR. Case 2. A 58-year-old white man had been receiving warfarin for 8 years for a cerebrovascular accident. Initiation of a high-protein, low-carbohydrate diet resulted in a 30% increase (from 26.25 to 37.5 mg/wk) in warfarin dose. His warfarin dose was reduced to the original dose after he stopped the high-protein, low-carbohydrate diet. DISCUSSION: The Naranjo probability scale indicated a possible adverse effect between warfarin and high-protein diets. High-protein diets have been shown to increase serum albumin levels. This may result in more warfarin binding to serum albumin, thereby decreasing the anticoagulant effect of warfarin. The increase of albumin occurs rapidly after initiation of a high-protein diet and appears to promptly affect anticoagulation therapy with warfarin. CONCLUSIONS: These cases indicate a significant interaction between high-protein, low-carbohydrate diets and warfarin therapy. Patients receiving warfarin therapy should be educated on and monitored for the potential interaction that occurs with warfarin therapy and high-protein, low-carbohydrate diets.

scholarly journals High protein diet: benefits and risks

2021 ◽  
Vol 17 (4) ◽  
pp. 393-400
Author(s):  
M. V. Altashina ◽  
E. V. Ivannikova ◽  
E. A. Troshina
Keyword(s):  
Cardiovascular Diseases ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Eating Patterns ◽  
Nonalcoholic Fatty Liver ◽  
High Protein Diets ◽  
Protein Diets ◽  
Mineral Bone Density

The nature of human nutrition has become increasingly important as an effective element in the prevention and treatment of many pathologies, especially obesity, type 2 diabetes and cardiovascular diseases. High protein diets are some of the most popular eating patterns and the Dukan diet has taken the lead in popularity among the diets of this type. An increase of protein in the diet is effective in reducing body weight, primarily due to the loss of adipose tissue, without a significant effect on muscle mass. Another advantage of a high-protein diet is earlier and longer satiety compared to other diets, which makes it comfortable for use. Besides obesity, high protein diets are presumably effective for treating such diseases as nonalcoholic fatty liver disease, diabetes mellitus and cardiovascular diseases However, despite the important advantages, this nutritional model is not universal and is contraindicated in patients with diseases of liver, kidneys and osteoporosis. Besides, the prolonged use of a high protein diet may increase the risks of urolithiasis and reduced mineral bone density even for healthy individuals. Thus, the increase in the proportion of protein in the diet should take place exclusively under the supervision of a physician.

Deteriorated glucose metabolism with a high-protein, low-carbohydrate diet in db mice, an animal model of type 2 diabetes, might be caused by insufficient insulin secretion

2015 ◽  
Vol 56 (1) ◽  
pp. 237-246 ◽  
Author(s):  
Emi Arimura ◽  
Wijang Pralampita Pulong ◽  
Ancah Caesarina Novi Marchianti ◽  
Miwa Nakakuma ◽  
Masaharu Abe ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Animal Model ◽  
Insulin Secretion ◽  
Glucose Metabolism ◽  
High Protein ◽  
Carbohydrate Diet ◽  
Low Carbohydrate Diet ◽  
Low Carbohydrate

Beneficial effects of low-carbohydrate-high-protein diets in long-term diabetic rats

Metabolism ◽  
1980 ◽  
Vol 29 (5) ◽  
pp. 421-428 ◽  
Author(s):  
Eberhard G. Siegel ◽  
Volker E. Trapp ◽  
Claes B. Wollheim ◽  
Albert E. Renold ◽  
Felix H. Schmidt
Keyword(s):  
Diabetic Rats ◽  
High Protein ◽  
Beneficial Effects ◽  
Low Carbohydrate ◽  
High Protein Diets ◽  
Protein Diets

scholarly journals High-Protein Diets for Treatment of Type 2 Diabetes Mellitus: A Systematic Review

2019 ◽  
Vol 10 (4) ◽  
pp. 621-633 ◽  
Author(s):  
Samar Malaeb ◽  
Caitlin Bakker ◽  
Lisa S Chow ◽  
Anne E Bantle
Keyword(s):  
Diabetes Mellitus ◽  
High Protein Diet ◽  
High Protein ◽  
Protein Diet ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Glycemic Outcomes ◽  
High Protein Diets ◽  
Protein Diets

ABSTRACT Diet has the potential to be a powerful and cost-effective tool for treatment of type 2 diabetes mellitus (T2D). High-protein diets have shown promise for this purpose. The objective of this systematic review was to evaluate whether high-protein diets improve glycemic outcomes in people with T2D. We conducted a systematic search of literature published prior to 1 February 2018 to find clinical studies of high-protein diet patterns for treatment of T2D in human participants. A high-protein diet was defined as a diet with protein content greater than that of a typical diet in the United States (>16% of total energy as protein). Studies were excluded if weight loss >5% occurred or if no glycemic outcomes were measured. A total of 21 independent articles met our criteria and were included. Most tested diets had a protein content of around 30% of total energy. Many studies supported the use of high-protein diets for patients with T2D, but were limited by small size (n = 8–32) and short duration (1–24 wk). Randomized controlled trials tended to be larger (n = 12–419) and longer (6 wk–2 y), and had mixed results, with many trials showing no difference between a high-protein diet and control. Many randomized controlled trials were limited by low compliance and high dropout rates >15%. There were no consistent beneficial or detrimental effects of high-protein diets on renal or cardiovascular outcomes. Evidence was insufficient to recommend 1 type of protein (plant or animal) over the other. Our review suggests that interventions to improve compliance with diet change over the long term may be equally important as specific macronutrient recommendations for treatment of T2D.

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