Panel

2010 ◽  
pp. 432-454
Author(s):  
Annika Hinze ◽  
Jean Bacon ◽  
Alejandro Buchmann ◽  
Sharma Chakravarthy ◽  
Mani Chandi ◽  
...  
Keyword(s):  
Distributed Systems ◽  
Sensor Networks ◽  
Panel Discussion ◽  
Streaming Data ◽  
The Other ◽  
Software Architectures ◽  
Pros And Cons ◽  
Basic Concepts ◽  
Event Based

This chapter is a panel discussion in writing. The field of event-based systems finds researchers from a number of different backgrounds: distributed systems, streaming data, databases, middleware, and sensor networks. One of the consequences is that everyone comes to the field with a slightly different mindset and different expectations and goals. In this chapter, we try to capture some of the voices that are influential in our field. Seven panellists from academia and industry were invited to answer and discuss questions about event-based systems. The questions were distributed via email, to which each participant replied their initial set of answers. In a second round every panelist was given the opportunity to expand their statement and discuss the contributions of the other panellists. The questions asked can be grouped into two types. Questions in the first group refer to each participant’s understanding of the basic concepts of event-based systems (EBS), the pros and cons of EBS, typical assumptions of the field and how they understood EBS to fit into the overall landscape of software architectures. The second group of questions pointed to the future of EBS, possible killer applications and the challenges that EBS researchers in academia and industry need to address in the medium and long term. The next section gives each panellist’s initial statements as well as their comments to other participants’ contributions. Each participant’s section starts with a short introduction of the panellist and their work. In the final section, we compare and reflect on the statements and discussions that are presented by the seven panellists.

scholarly journals A Comparative Analysis of Distributed and Parallel Computing

2018 ◽  
pp. 60-67
Keyword(s):  
Parallel Computing ◽  
Comparative Analysis ◽  
Distributed Systems ◽  
Data Centers ◽  
Parallel Systems ◽  
The Other ◽  
Pros And Cons ◽  
Distributed And Parallel Computing ◽  
Better Than ◽  
Computing Models

In the age of emerging technologies, the amount of data is increasing very rapidly. Due to massive increase of data the level of computations are increasing. Computer executes instructions sequentially. But the time has now changed and innovation has been advanced. We are currently managing gigantic data centers that perform billions of executions on consistent schedule. Truth be- hold, if we dive deep into the processor engineering and mechanism, even a successive machine works parallel. Parallel computing is growing faster as a substitute of distributing computing. The performance to functionality ratio of parallel systems is high. Also, the I/O usage of parallel systems is lower because of ability to perform all operations simultaneously. On the other hand, the performance to functionality ratio of distributed systems is low. The I/O usage of distributed systems is higher because of incapability to perform all operations simultaneously. In this paper, an overview of distributed and parallel computing is described. The basic concept of these two computing is discussed. In addition to this, pros and cons of distributed and parallel computing models are described. Through many aspects, we can conclude that parallel systems are better than distributed systems.

Radioimmunotherapy for treatment of acute myeloid leukaemia and myelodysplastic syndrome

2005 ◽  
Vol 44 (03) ◽  
pp. 107-117
Author(s):  
R. G. Meyer ◽  
W. Herr ◽  
A. Helisch ◽  
P. Bartenstein ◽  
I. Buchmann
Keyword(s):  
Acute Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Primary Tumour ◽  
The Other ◽  
Haematopoietic Stem Cell ◽  
Other Hand ◽  
Primary Reduction ◽  
The One ◽  
Acute Myeloid

SummaryThe prognosis of patients with acute myeloid leukaemia (AML) has improved considerably by introduction of aggressive consolidation chemotherapy and haematopoietic stem cell transplantation (SCT). Nevertheless, only 20-30% of patients with AML achieve long-term diseasefree survival after SCT. The most common cause of treatment failure is relapse. Additionally, mortality rates are significantly increased by therapy-related causes such as toxicity of chemotherapy and complications of SCT. Including radioimmunotherapies in the treatment of AML and myelodyplastic syndrome (MDS) allows for the achievement of a pronounced antileukaemic effect for the reduction of relapse rates on the one hand. On the other hand, no increase of acute toxicity and later complications should be induced. These effects are important for the primary reduction of tumour cells as well as for the myeloablative conditioning before SCT.This paper provides a systematic and critical review of the currently used radionuclides and immunoconjugates for the treatment of AML and MDS and summarizes the literature on primary tumour cell reductive radioimmunotherapies on the one hand and conditioning radioimmunotherapies before SCT on the other hand.

Hidden “holes” in the capital of banks and the supply of credit to the real sector of economy

2018 ◽  
pp. 49-68 ◽  
Author(s):  
M. E. Mamonov
Keyword(s):  
Credit Risk ◽  
The Other ◽  
Real Sector ◽  
Capital Management ◽  
Loan Loss ◽  
Short Term ◽  
The Real ◽  
Ex Post ◽  
The One

Our analysis documents that the existence of hidden “holes” in the capital of not yet failed banks - while creating intertemporal pressure on the actual level of capital - leads to changing of maturity of loans supplied rather than to contracting of their volume. Long-term loans decrease, whereas short-term loans rise - and, what is most remarkably, by approximately the same amounts. Standardly, the higher the maturity of loans the higher the credit risk and, thus, the more loan loss reserves (LLP) banks are forced to create, increasing the pressure on capital. Banks that already hide “holes” in the capital, but have not yet faced with license withdrawal, must possess strong incentives to shorten the maturity of supplied loans. On the one hand, it raises the turnovers of LLP and facilitates the flexibility of capital management; on the other hand, it allows increasing the speed of shifting of attracted deposits to loans to related parties in domestic or foreign jurisdictions. This enlarges the potential size of ex post revealed “hole” in the capital and, therefore, allows us to assume that not every loan might be viewed as a good for the economy: excessive short-term and insufficient long-term loans can produce the source for future losses.

Interrelationships between municipal spatial policy strategy and airport operation and development. Lodz Airport case study

2018 ◽  
Vol 59 (1) ◽  
pp. 65-79
Author(s):  
Katarzyna Nikorowicz-Zatorska
Keyword(s):  
Land Use ◽  
Urban Planning ◽  
Cultural Development ◽  
The Other ◽  
Local Authorities ◽  
Spatial Management ◽  
The One ◽  
Surrounding Areas

Abstract The present paper focuses on spatial management regulations in order to carry out investment in the field of airport facilities. The construction, upgrades, and maintenance of airports falls within the area of responsibility of local authorities. This task poses a great challenge in terms of organisation and finances. On the one hand, an active airport is a municipal landmark and drives local economic, social and cultural development, and on the other, the scale of investment often exceeds the capabilities of local authorities. The immediate environment of the airport determines its final use and prosperity. The objective of the paper is to review legislation that affects airports and the surrounding communities. The process of urban planning in Lodz and surrounding areas will be presented as a background to the problem of land use management in the vicinity of the airport. This paper seeks to address the following questions: if and how airports have affected urban planning in Lodz, does the land use around the airport prevent the development of Lodz Airport, and how has the situation changed over the time? It can be assumed that as a result of lack of experience, land resources and size of investments on one hand and legislative dissonance and peculiar practices on the other, aviation infrastructure in Lodz is designed to meet temporary needs and is characterised by achieving short-term goals. Cyclical problems are solved in an intermittent manner and involve all the municipal resources, so there’s little left to secure long-term investments.

Pengaruh Financial Leverage terhadap Financial Performance pada Sektor Industri Manufaktur yang Terdaftar di Bursa Efek Indonesia (BEI) Periode 2015

2018 ◽  
Vol 9 (2) ◽  
pp. 33-48
Author(s):  
Rivaldy Februansyah ◽  
Ika Yanuarti
Keyword(s):  
Financial Performance ◽  
Manufacturing Sector ◽  
Linear Regression Analysis ◽  
The Other ◽  
Debt Ratio ◽  
Financial Leverage ◽  
Coverage Ratio ◽  
Equity Ratio ◽  
Internal Fund

The manufacturing sector is one of the most dominant economic sectors in in achieving growth and development in Indonesia. It needs adequate fund to develop its business. The sources of fund are from internal and external. The firm usually optimized the usage of internal fund prior to external fund. The internal fund comes from equity while the external funds are from debt and stock. Debt is also known as financial leverage. There is a phenomenon that the usage of debt increased the firm’s financial performance, since interest on debt could lower the payment of tax (tax shield). On the other side, the higher the financial leverage the higher the risk of bankruptcy. This research aims to analyze whether financial leverage has an influence on financial performance in the manufacturing sector listed on the Indonesia Stock Exchange (IDX) period 2015. The method of analysis used in this research is multiple linear regression analysis. This research uses quantitative approach with a sample of 140 listed companies in the manufacturing industry. The firm’s financial performance could be measured by the financial ratios. Financial Leverage ratios are ratios that measure the ability of firm’s to meet its financial obligation and the level of usage debt as compared to equity. There are several financial leverage ratios that used in this research, such as Debt Ratio (DR), Debt to Equity Ratio (DER), Interest Coverage Ratio (ICR), and Long Term Debt Ratio (LTDR). Financial performance indicates the ability of firm to generate profit and measured by Profitability Ratio. Return on Asset (ROA) is one of the Profitability Ratio. The statistical result shows that Debt Ratio (DR) negatively affect Return on Asset (ROA) and Interest Coverage Ratio (ICR) positively affect Return on Asset (ROA). Meanwhile, Debt to Equity Ratio (DER) and Long Term Debt Ratio (LTDR) did not affect Return on Asset (ROA). On the other hand, result shows that Debt Ratio (DR), Debt to Equity Ratio (DER), Interest Coverage Ratio (ICR), and Long Term Debt Ratio (LTDR) affect Return on Asset (ROA) simultaneously. Keywords: Financial Leverage, Debt Ratio (DR), Debt to Equity Ratio (DER), Interest Coverage Ratio (ICR), Long Term Debt Ratio (LTDR), Financial Performance, Return on Assets (ROA)

The effects of long-term vigorous endurance exercise on the coronary arteries

2019 ◽  
Vol 67 (2) ◽  
Keyword(s):  
Endurance Training ◽  
Coronary Atherosclerosis ◽  
Calcium Score ◽  
The Other ◽  
Disease Phenotype ◽  
Male Athletes ◽  
Artery Disease ◽  
Future Work ◽  
Summary Data

Moderate endurance training is known to improve cardiovascular risk factors, and prolongs life expectancy. On the other hand, there has been some discussion whether “too much” exercise might have a contrarious effect by accelerating coronary atherosclerosis. The goal of this review was to evaluate the current literature on the effects of long-term vigorous endurance training on the coronary vasculature. In summary, data point to an increased calcium score, and a higher burden of atherosclerotic plaque in male athletes compared to sedentary controls. However, the plaques found in athletes were more prone to be calcified. The pathogenesis and clinical relevance of this athlete coronary artery disease phenotype remains incompletely understood and represents an area of important future work.

The effects of long-term vigorous endurance exercise on the coronary arteries

2019 ◽  
Vol 67 (2) ◽  
Keyword(s):  
Endurance Training ◽  
Coronary Atherosclerosis ◽  
Calcium Score ◽  
The Other ◽  
Disease Phenotype ◽  
Male Athletes ◽  
Artery Disease ◽  
Future Work ◽  
Summary Data

Moderate endurance training is known to improve cardiovascular risk factors, and prolongs life expectancy. On the other hand, there has been some discussion whether “too much” exercise might have a contrarious effect by accelerating coronary atherosclerosis. The goal of this review was to evaluate the current literature on the effects of long-term vigorous endurance training on the coronary vasculature. In summary, data point to an increased calcium score, and a higher burden of atherosclerotic plaque in male athletes compared to sedentary controls. However, the plaques found in athletes were more prone to be calcified. The pathogenesis and clinical relevance of this athlete coronary artery disease phenotype remains incompletely understood and represents an area of important future work.

Basic Concepts and Definitions of Allergology

2019 ◽  
Author(s):  
Zoran Vrucinic
Keyword(s):  
Immune Reaction ◽  
The Body ◽  
The Other ◽  
Specific Response ◽  
Other Hand ◽  
Medical Vocabulary ◽  
The Future ◽  
Basic Concepts ◽  
Basic Insight ◽  
Insight Into

The future of medicine belongs to immunology and alergology. I tried to not be too wide in description, but on the other hand to mention the most important concepts of alergology to make access to these diseases more understandable, logical and more useful for our patients, that without complex pathophysiology and mechanism of immune reaction,we gain some basic insight into immunological principles. The name allergy to medicine was introduced by Pirquet in 1906, and is of Greek origin (allos-other + ergon-act; different reaction), essentially representing the reaction of an organism to a substance that has already been in contact with it, and manifested as a specific response thatmanifests as either a heightened reaction, a hypersensitivity, or as a reduced reaction immunity. Synonyms for hypersensitivity are: altered reactivity, reaction, hypersensitivity. The word sensitization comes from the Latin (sensibilitas, atis, f.), which means sensibility,sensitivity, and has retained that meaning in medical vocabulary, while in immunology and allergology this term implies the creation of hypersensitivity to an antigen. Antigen comes from the Greek words, anti-anti + genos-genus, the opposite, anti-substance substance that causes the body to produce antibodies.

Comparison between DOA Estimation Subspace methods for incoherent and coherent signals

2015 ◽  
Vol 1 ◽  
pp. 18
Author(s):  
Ahmed Abdalla ◽  
Suhad Mohammed ◽  
Tang Bin ◽  
Jumma Mary Atieno ◽  
Abdelazeim Abdalla
Keyword(s):  
Linear Array ◽  
Doa Estimation ◽  
Far Field ◽  
Matlab Simulation ◽  
Subspace Methods ◽  
Coherent Signals ◽  
Uniform Linear Array ◽  
Pros And Cons ◽  
Basic Concepts ◽  
And Performance

This paper considers the problem of estimating the direction of arrival (DOA) for the both incoherent and coherent signals from narrowband sources, located in the far field in the case of uniform linear array sensors. Three different methods are analyzed. Specifically, these methods are Music, Root-Music and ESPRIT. The pros and cons of these methods are identified and compared in light of different viewpoints. The performance of the three methods is evaluated, analytically, when possible, and by Matlab simulation. This paper can be a roadmap for beginners in understanding the basic concepts of DOA estimation issues, properties and performance.

scholarly journals Private retirement resorts in South Africa: Guidelines for wellness and sustainability in the long term.

2013 ◽  
Vol 32 (1) ◽  
Author(s):  
Andries C. Hauptfleisch
Keyword(s):  
South Africa ◽  
Knowledge Base ◽  
Quantitative Data ◽  
Qualitative Data ◽  
Well Being ◽  
The Other ◽  
Literature Study ◽  
Optimal Profile

Unsubsidised private retirement resorts in South Africa developed during the last three decades present residents with many challenges. There is no existing generally accepted knowledge base or guidelines to serve this sensitive market. The research objective was to establish which elements are experienced by residents of retirement resorts as satisfactory and which as problematic. A literature study was also undertaken. Quantitative as well as qualitative data were obtained by means of structured questionnaires, interviews and a seminar. The results reported pertain to eight resorts in the east of Pretoria, four in Bloemfontein and two in Knysna. The study is currently being extended to other centres. The quantitative data is arranged in order of the priorities set by the biggest group (Pretoria), with the other groups in comparison. So the research was based on the sourcing of quantitative and qualitative data, as well as on descriptive evaluations. The results offer insightful knowledge and guidelines towards establishing an optimal profile for the development of long-term sustainable private retirement resorts. The implications and value of this study are that both developers of retirement resorts and prospective residents are provided with guidelines to better equip them to evaluate a specific retirement resort with regard to the sustainable well- being of residents long-term.

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