Predicting Complex Patterns of Human Movements Using Bayesian Online Learning in Medical Imaging Applications

Author(s):  
Francisco Gómez ◽  
Fabio Martínez ◽  
Eduardo Romero

Medical images, in its tough sense, are fundamental in most clinical procedures and have become part of the medical act. Different acquisition methodologies result in a large variety of challenges or diagnostic tasks. Overall, most applications are dedicated to imaging structures so that complex measurements may be achieved. However, function analysis necessitates imaging structures through the time, either at the level of the image itself or at the interaction strategy between the user and the image. This chapter presents a Bayesian Framework which allows an adequate temporal follow up of very complex human movements, which somehow have been imaged. The Bayesian strategy is implemented through a particle filter, resulting in real time tracking of these complex patterns. Two different imaged patterns illustrate the potential of the procedure: a precise tracking a pathologist in a Virtual Microscopy context and a temporal follow up of gait patterns.

Author(s):  
Bernardo Breve ◽  
Stefano Cirillo ◽  
Mariano Cuofano ◽  
Domenico Desiato

AbstractGestural expressiveness plays a fundamental role in the interaction with people, environments, animals, things, and so on. Thus, several emerging application domains would exploit the interpretation of movements to support their critical designing processes. To this end, new forms to express the people’s perceptions could help their interpretation, like in the case of music. In this paper, we investigate the user’s perception associated with the interpretation of sounds by highlighting how sounds can be exploited for helping users in adapting to a specific environment. We present a novel algorithm for mapping human movements into MIDI music. The algorithm has been implemented in a system that integrates a module for real-time tracking of movements through a sample based synthesizer using different types of filters to modulate frequencies. The system has been evaluated through a user study, in which several users have participated in a room experience, yielding significant results about their perceptions with respect to the environment they were immersed.


1981 ◽  
Vol 11 (3) ◽  
pp. 535-550 ◽  
Author(s):  
A. H. Mann ◽  
R. Jenkins ◽  
E. Belsey

SYNOPSISOne hundred patients, selected to be representative of those attending general practitioners with non-psychotic psychiatric disorders were followed up for one year. standard assessments of mental state, personality, social stresses and supports were carried out for each patient at the outset and after a year.The outcome for this cohort determined both by the level of psychiatric morbidity at interview after one year and by the pattern of the psychiatric morbidity during the year has been analysed with reference to the assessment measures. Discriminant function analysis indicates that the initial estimate of the severity of the psychiatric morbidity and a rating of the quality of the social life at the time of follow-up are the only factors that significantly predict the psychiatric state after one year. Social measures also predict a pattern of illness charactorized by a rapid recovery after the initial assessemtn. Patients who reported continuous psychiatric morbidity during the year were, older, physically ill and very likely to have recevied psychotropic drugs. Receipt of this medication during the year was associated with initial assessments of abnormality of personality, older age, and a diagnosis of depression.The findings of this study are seen to support a triaxial assessment and classification of non-psychotic psychiatirc disorders, with symptoms, personality and social state being rated independently.


2021 ◽  
pp. 112070002110184
Author(s):  
Andrey A Korytkin ◽  
Younes M El Moudni ◽  
Yana S Novikova ◽  
Kirill A Kovaldov ◽  
Ekaterina A Morozova

Background: The supercapsular percutaneously-assisted total hip (SuperPATH) approach is a muscle sparing surgical technique for total hip arthroplasty (THA). The literature reports good clinical and functional results of the SuperPATH technique in the short term. We aimed to compare early outcomes and gait analysis of THA using the mini posterior approach (MPA) and supercapsular percutaneously-assisted total hip (SuperPATH) approach. Methods: 44 patients who underwent THA, were randomly allocated to either MPA or SuperPATH. The data were then collected prospectively (preoperatively and postoperatively at 6 weeks). Plain anteroposterior radiographs of the pelvis and instrumental gait analysis were obtained. The visual analogue scale (VAS), Harris Hip Score (HHS) and Hip disability and Osteoarthritis Outcome Scores (HOOS) were used to assess functional and clinical outcomes. Results: No significant difference was found in patients’ surgical outcomes. Patients in the SuperPATH group had less pain according to the VAS score at follow-up than the MPA group ( p < 0.01). There was also a significant improvement in HHS and HOOS scores for all patients ( p < 0.001) with the SuperPATH group showing superior changes. The comparison of mean differences in gait velocity between preoperative and 6 weeks postoperative result, revealed improvement in the SuperPATH group over the MPA group ( p = 0.06). Limping was more persistent in the MPA group. Kinematic parameters demonstrated improved hip joint excursion slightly higher in the MPA group. There was no significant improvement in kinetic and kinematic parameters at different walking moments for all patients at 6 weeks compared to preoperative gait patterns. Conclusions: SuperPATH and MPA both show excellent results. This study reveals that the SuperPATH technique was associated with lower postoperative pain levels, and higher physical function and quality of life. Improved functional outcomes allowed earlier postoperative rehabilitation and faster recovery. Specific improvement in gait patterns were identified with nonsignificant differences between the 2 approaches at 6 weeks follow-up.


1983 ◽  
Vol 13 (2) ◽  
pp. 373-383 ◽  
Author(s):  
J. R. M. Copeland

SYNOPSISA consecutive series of 94 patients recently admitted to hospital from a defined catchment area and diagnosed as having a depressive illness were examined using standardized techniques for eliciting mental state, etc. The overlap between psychotic and neurotic diagnoses was 8·5% on discriminant function analysis of mental state items. A sub-sample of 71 patients was given a comprehensive postal and case record follow-up 5 years later. When patients developing organic and other complicating illnesses were excluded, those suffering from psychotic depression showed a significantly poorer outcome, as defined by relapse and required lengths of hospital care, than those diagnosed as suffering from neurotic depression.


Author(s):  
Charlesnika T. Evans ◽  
Benjamin J. DeYoung ◽  
Elizabeth L. Gray ◽  
Amisha Wallia ◽  
Joyce Ho ◽  
...  

Abstract Objective Healthcare workers (HCWs) are a high priority group for COVID-19 vaccination and serve as sources for information for the public. This analysis assessed vaccine intentions, factors associated with intentions, and change in uptake over time in HCWs. Methods A prospective cohort study of COVID-19 seroprevalence was conducted with HCWs in a large healthcare system in the Chicago area. Participants completed surveys (November 25, 2020-January 9, 2021 and April 24-July 12, 2021) on COVID-19 exposures, diagnosis and symptoms, demographics, and vaccination status. Results Of 4,180 HCWs who responded to a survey, 77.1% indicated they intended to get the vaccine; in this group, 23.2% had already received at least one dose of the vaccine (23.2%), 17.4% were unsure, and 5.5% reported that they would not get the vaccine. Factors associated with intention or vaccination were being exposed to clinical procedures (vs no procedures) and having a negative serology test for COVID-19 (vs no test) (adjusted odds ratio (AOR)=1.39, 95% Confidence Interval (CI) 1.16-1.65, AOR=1.46, 95% CI 1.24-1.73, respectively). Nurses (vs physicians, AOR=0.24 95% CI 0.17-0.33), non-Hispanic Black (vs Asians, AOR=0.35, 95% CI 0.21-0.59), and women (vs men, AOR=0.38, 95% CI 0.30-0.50) had lower odds of intention to get vaccinated. By 6-months follow-up, over 90% of those who had previously been unsure were vaccinated, while 59.7% of those who previously reported no intention of getting vaccinated, were vaccinated. Conclusions COVID-19 vaccination in HCWs was high, but variability in vaccination intention exists. Targeted messaging coupled with vaccine mandates can support uptake.


Author(s):  
Priscilla Song

This chapter focuses on how Dr. Huang and his staff have contested international biomedical research protocols and devised new methods to assess the effectiveness of their experimental human olfactory ensheathing glial cell transplantation surgery. These strategies include developing improved measurement scales to capture post-surgical differences in bodily function and feeling; inviting foreign doctors to witness clinical procedures for themselves; conducting follow-up studies with former patients; and attempting to publish scientific reports in internationally credible journals. By examining the ways in which New Century clinicians have evaluated the effectiveness of the fetal cell transplantation procedure, this chapter raises key questions about the ethics and epistemology of clinical experimentation at the “cutting edge” of biomedical practice in contemporary China. It demonstrates how new modes of validation are emerging as viable alternatives to the hegemonic discourse of randomized controlled trials that has dominated the quest for “evidence” in experimental medicine.


2021 ◽  
Vol 5 (3) ◽  
pp. 1-10
Author(s):  
Yuzhuo Li ◽  

Background: To determine whether the Hounsfield Unit (HU) value of no-contrast computer computed tomography (NCCT) might offer better guidance in the selection of RIRS or PCNL in renal stones of 2-3 cm. Methods: A total of 158 patients with kidney stones (2-3 cm) who underwent PCNL/RIRS from March 2016 to January 2019 were enrolled in this study. Age, gender, stone sizes, locations, average HU value of stones, surgery time, hospital stay time, stone-free rate, and complications at the time of hospitalization and 3-month follow-up were measured to identify the surgery efficiency. Results: Upon consideration of the HU value, the mean surgery time was significantly decreased in RIRS comparing to the control RIRS (cRIRS) group (47.73 ± 15.52 vs. 72.41 ± 27.71 min, P < 0.05). Statistically, the surgery time was strongly influenced by the HU values both in RIRS (OR 93.8, P < 0.01) and PCNL (OR 8.21, P < 0.05). HU values proved to have a strong positive relation with surgery time in RIRS while a low positive relation in PCNL (P < 0.05). Conclusion: Overall, for renal stones of 2-3 cm, RIRS might be a safe and efficacious treatment option if the HU value and other parameters could be comprehensively accounted for. Individual precision surgery might provide ideal treatment and prognosis for patients requiring long-term continuous clinical procedures.


1975 ◽  
Vol 41 (3) ◽  
pp. 735-739
Author(s):  
George R. Holmes ◽  
Anna L. Stout ◽  
Arthur L. Rosenkrantz ◽  
D. Wayne Bickham ◽  
Robert C. Schnackenberg

A 3-yr. follow-up study, using 5 dependent measures of academic performance, was accomplished on 42 of the original 50 5 1/2-yr.-old youngsters used in the Adkins, et al. (1971) study. A preliminary comparison of the de Hirsch method of classification of children as of potentially high academic risk clearly suggests the possibility of using discriminant function analysis with the de Hirsch Predictive Index. A strategy for evaluating interventions on high-risk children is suggested.


1989 ◽  
Vol 19 (1) ◽  
pp. 189-197 ◽  
Author(s):  
Peter Huxley ◽  
Hitesh Raval ◽  
Jacky Korer ◽  
Caroline Jacob

SynopsisOut of 141 new referrals to a Social Services Department 101 were assessed at inception and twelve-month follow-up using the Present State Examination (PSE), the Social Maladjustment Schedule (SMS) and the Case Review Form (CRF). Mental illness, financial and housing problems were the three problems most frequently identified by the social workers. At inception 72 (51%) of the subjects were PSE cases (ID > 5) and 25% at follow-up. The type of social work help offered to cases and non-cases did not differ.Social and clinical data collected at inception and follow-up were used to classify (using discriminant function analysis) caseness at inception and follow-up and clinical change. Caseness at inception (82% of subjects were correctly classified) was associated with depression, subjective social problems and poverty. Caseness at follow-up (74% correctly classified) was associated with poor coping abilities at inception and clinical features of depression. Clinical change (worsening) (71% correctly classified) was associated with seeing a Community Psychiatric Nurse and poor coping abilities at inception. The ability to classify correctly cases and change was enhanced when additional data from follow-up interviews were used. In the PSE cases, only clinical worsening was correctly classified by a high GHQ score at inception, age and poor coping abilities. The last result is similar to that obtained in general practice by Mann et al. (1981).


2019 ◽  
Vol 4 (1) ◽  
pp. 460-464
Author(s):  
Eckart Grundmann ◽  
Tanja Baumgartner

AbstractEurythmy is a performing art based on anthroposophy which tries to make non-visible forces visible by human movements. According to the concept of anthroposophy a eurythmist is capable to come into an exchange with the life forces of organisms through his movements. In a field experiment – executed by the Institute ArteNova in cooperation with an apple farmer – a eurythmist treated trees of two apple varieties with a sequence of eurythmic gestures to observe the impact on the fruit quality. The apples showed no differences in the laboratory test of sugar content and firmness. In the sensory test, significant differences could be found in several parameters like freshness, crunchiness or the total judgement. The results present a basic effect of human movements on the taste of plants. Furthermore, it was possible to find appropriate movements for pre-determined aims. Eurythmic movements could be seen as a possible method for agricultural systems which refuse pesticides and other synthetic substances. Follow-up experiments with different varieties, fruits, and places should verify the effects.


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