SMART

Author(s):  
Esteban Pino ◽  
Dorothy Curtis ◽  
Thomas Stair ◽  
Lucila Ohno-Machado

Patient monitoring is important in many contexts: at mass-casualty disaster sites, in improvised emergency wards, and in emergency room waiting areas. Given the positive history of use of monitoring systems in the hospital during surgery, in the recovery room, or in an intensive care unit, the authors sought to use recent technological advances to enable patient monitoring in more diverse circumstances: at home, while traveling, and in some less well-monitored areas of a hospital. This chapter presents the authors’ experiences in designing, implementing and deploying a wireless disaster management system prototype in a real hospital environment. In addition to a review of related systems, the sensors, algorithms and infrastructure used in our implementation are presented. Finally, general guidelines for ubiquitous methodologies and tools are shared based on the lessons learned from the actual implementation.

Author(s):  
Esteban Pino ◽  
Dorothy Curtis ◽  
Thomas Stair ◽  
Lucila Ohno-Machado

Patient monitoring is important in many contexts: at mass-casualty disaster sites, in improvised emergency wards, and in emergency room waiting areas. Given the positive history of use of monitoring systems in the hospital during surgery, in the recovery room, or in an intensive care unit, the authors sought to use recent technological advances to enable patient monitoring in more diverse circumstances: at home, while traveling, and in some less well-monitored areas of a hospital. This paper presents the authors’ experiences designing, implementing and deploying a wireless disaster management system prototype in a real hospital environment. In addition to a review of related systems, the sensors, algorithms and infrastructure used in our implementation are presented. Finally, general guidelines for ubiquitous methodologies and tools are shared based on the lessons learned from the actual implementation.


Author(s):  
Esteban Pino ◽  
Dorothy Curtis ◽  
Thomas Stair ◽  
Lucila Ohno-Machado

Patient monitoring is important in many contexts: at mass-casualty disaster sites, in improvised emergency wards, and in emergency room waiting areas. Given the positive history of use of monitoring systems in the hospital during surgery, in the recovery room, or in an intensive care unit, the authors sought to use recent technological advances to enable patient monitoring in more diverse circumstances: at home, while traveling, and in some less well-monitored areas of a hospital. This paper presents the authors’ experiences designing, implementing and deploying a wireless disaster management system prototype in a real hospital environment. In addition to a review of related systems, the sensors, algorithms and infrastructure used in our implementation are presented. Finally, general guidelines for ubiquitous methodologies and tools are shared based on the lessons learned from the actual implementation.


Author(s):  
Konstantinos M. Siassiakos ◽  
Athina A. Lazakidou

Cost reduction pressures and the need for shortened in-patient stays are promoting the use of wireless patient monitoring systems in hospitals. Their contribution to better process management, superior flexibility and increased efficiency within hospitals is further underlining the appeal of wireless networking options for patient monitoring systems. Wireless connectivity has encouraged an overall rise in productivity through improved workflow and data management. Wireless patient monitors have also supported enhanced flexibility within the hospital environment by enabling remote monitoring of patients. TETRA technology provides several ways of protecting the privacy and security of communication, such as authentication, air interface encryption and end-to-end encryption. The objective of this chapter is to study how simply can a healthcare professional collect physiological data from mobile and/or remote patients and how securely and reliably health information can be transferred from emergency places to hospitals through a TETRA network.


2019 ◽  
Vol 12 ◽  
pp. 9-54
Author(s):  
Christophe Helmke ◽  
Claire E. Ebert ◽  
Jaime J. Awe ◽  
Julie A. Hoggarth

The Belize Valley figures prominently in the history of Maya archaeology as the birthplace of settlement pattern surveys, where Gordon R. Willey and his colleagues conducted their pioneering research project, from 1954 to 1956. Six decades on, settlement surveys are an integral part of archaeological research strategies not only across the Maya area, but globally. With the advent of LiDAR technology, settlement surveys enter a new developmental phase, and we take this opportunity to review the history and progress of these surveys in the Belize Valley. We focus on one particular archaeological site, Baking Pot, so as to better illustrate the methods and technological advances that have been brought to bear in the mapping of one ancient Maya city-state. Now that the survey of this ancient settlement is nearing completion, we veer from traditional settlement surveys that in principle focus on unbounded central places and centroids, in an attempt to tackle an important question, which to date has remained conspicuously understudied, that of borders and boundaries. Using a series of geospatial analyses, we investigate the potential of these approaches for reconstructing ancient polity boundaries and as lessons learned we explore which methods are of greater utility and can be applied to other surveys in the Maya lowlands.


Author(s):  
Jacob J Glaser ◽  
Adam Czerwinski ◽  
Ashley Alley ◽  
Michael Keyes ◽  
Valentino Piacentino ◽  
...  

Background: REBOA has become an established adjunct to hemorrhage control. Prospective data sets are being collected, primarily from large, high volume trauma centers. There are limited data, and guidelines, to guide implementation and use outside of highly resourced environments. Smaller centers interested in adopting a REBOA program could benefit from closing this knowledge gap. Methods: A clinical series of cases utilizing REBOA from Grand Strand Medical Center, Myrtle Beach, South Carolina were reviewed. This represents early data from a busy community trauma center (ACS Level 2), from January 2017 to May 2018. Seven cases are identified and reported on, including outcomes. Considerations and ‘lessons learned’ from this early institutional experience are commented on.   Results: REBOA was performed by trauma and acute care surgeons for hemorrhage and shock (blunt trauma n=3, penetrating trauma n=2, no- trauma n=2). All were placed in Zone 1 (one initially was placed in zone 3 then advanced). Mean (SD) systolic pressure (mmHg) before REBOA was 43 (30); post REBOA pressure was 104 (19). N=4 were placed via an open approach, n=3 percutaneous (n=2 with ultrasound). All with arrest before placement expired (n=3) and all others survived. Complications are described.   Conclusions: REBOA can be a feasible adjunct for shock treatment in the community hospital environment, with outcomes comparable to large centers, and can be implemented by acute care and trauma surgeons. A rigorous process improvement program and critical appraisal process are critical in maximizing benefit in these centers.


Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1711
Author(s):  
Heba A. Gad ◽  
Autumn Roberts ◽  
Samirah H. Hamzi ◽  
Haidy A. Gad ◽  
Ilham Touiss ◽  
...  

Jojoba is a widely used medicinal plant that is cultivated worldwide. Its seeds and oil have a long history of use in folklore to treat various ailments, such as skin and scalp disorders, superficial wounds, sore throat, obesity, and cancer; for improvement of liver functions, enhancement of immunity, and promotion of hair growth. Extensive studies on Jojoba oil showed a wide range of pharmacological applications, including antioxidant, anti-acne and antipsoriasis, anti-inflammatory, antifungal, antipyretic, analgesic, antimicrobial, and anti-hyperglycemia activities. In addition, Jojoba oil is widely used in the pharmaceutical industry, especially in cosmetics for topical, transdermal, and parenteral preparations. Jojoba oil also holds value in the industry as an anti-rodent, insecticides, lubricant, surfactant, and a source for the production of bioenergy. Jojoba oil is considered among the top-ranked oils due to its wax, which constitutes about 98% (mainly wax esters, few free fatty acids, alcohols, and hydrocarbons). In addition, sterols and vitamins with few triglyceride esters, flavonoids, phenolic and cyanogenic compounds are also present. The present review represents an updated literature survey about the chemical composition of jojoba oil, its physical properties, pharmacological activities, pharmaceutical and industrial applications, and toxicity.


Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3712
Author(s):  
Ryan D. Rattray ◽  
Ben-Erik Van Wyk

The Lamiaceae is undoubtedly an important plant family, having a rich history of use that spans the globe with many species being used in folk medicine and modern industries alike. Their ability to produce aromatic volatile oils has made them valuable sources of materials in the cosmetic, culinary, and pharmaceutical industries. A thorough account of the taxonomic diversity, chemistry and ethnobotany is lacking for southern African Lamiaceae, which feature some of the region’s most notable medicinal and edible plant species. We provide a comprehensive insight into the Lamiaceae flora of southern Africa, comprising 297 species in 42 genera, 105 of which are endemic to the subcontinent. We further explore the medicinal and traditional uses, where all genera with documented uses are covered for the region. A broad review of the chemistry of southern African Lamiaceae is presented, noting that only 101 species (34%) have been investigated chemically (either their volatile oils or phytochemical characterization of secondary metabolites), thus presenting many and varied opportunities for further studies. The main aim of our study was therefore to present an up-to-date account of the botany, chemistry and traditional uses of the family in southern Africa, and to identify obvious knowledge gaps.


Molecules ◽  
2020 ◽  
Vol 26 (1) ◽  
pp. 175
Author(s):  
David M. Stevens ◽  
Rachael M. Crist ◽  
Stephan T. Stern

The chloroquine family of antimalarials has a long history of use, spanning many decades. Despite this extensive clinical experience, novel applications, including use in autoimmune disorders, infectious disease, and cancer, have only recently been identified. While short term use of chloroquine or hydroxychloroquine is safe at traditional therapeutic doses in patients without predisposing conditions, administration of higher doses and for longer durations are associated with toxicity, including retinotoxicity. Additional liabilities of these medications include pharmacokinetic profiles that require extended dosing to achieve therapeutic tissue concentrations. To improve chloroquine therapy, researchers have turned toward nanomedicine reformulation of chloroquine and hydroxychloroquine to increase exposure of target tissues relative to off-target tissues, thereby improving the therapeutic index. This review highlights these reformulation efforts to date, identifying issues in experimental designs leading to ambiguity regarding the nanoformulation improvements and lack of thorough pharmacokinetics and safety evaluation. Gaps in our current understanding of these formulations, as well as recommendations for future formulation efforts, are presented.


Author(s):  
Luciano César PC Leonel ◽  
Lucas P. Carlstrom ◽  
Christopher S. Graffeo ◽  
Avital Perry ◽  
Carlos Diogenes Pinheiro-Neto ◽  
...  

Abstract Objective This study was aimed to provide a key update to the seminal works of Prof. Albert L. Rhoton Jr., MD, with particular attention to previously unpublished insights from the oral tradition of his fellows, recent technological advances including endoscopy, and high-dynamic range (HDR) photodocumentation, and, local improvements in technique, we have developed to optimize efficient neuroanatomic study. Methods Two formaldehyde-fixed cadaveric heads were injected with colored latex to demonstrate step-by-step specimen preparation for microscopic or endoscopic dissection. One formaldehyde-fixed brain was utilized to demonstrate optimal three-dimensional (3D) photodocumentation techniques. Results Key steps of specimen preparation include vessel cannulation and securing, serial tap water flushing, specimen drainage, vessel injection with optimized and color-augmented latex material, and storage in 70% ethanol. Optimizations for photodocumentation included the incorporation of dry black drop cloth and covering materials, an imaging-oriented approach to specimen positioning and illumination, and single-camera stereoscopic capture techniques, emphasizing the three-exposure-times-per-eye approach to generating images for HDR postprocessing. Recommended tools, materials, and technical nuances were emphasized throughout. Relative advantages and limitations of major 3D projection systems were comparatively assessed, with sensitivity to audience size and purpose specific recommendations. Conclusion We describe the first consolidated step-by-step approach to advanced neuroanatomy, including specimen preparation, dissection, and 3D photodocumentation, supplemented by previously unpublished insights from the Rhoton fellowship experience and lessons learned in our laboratories in the past years such that Prof. Rhoton's model can be realized, reproduced, and expanded upon in surgical neuroanatomy laboratories worldwide.


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