Malaria Detection System Using Convolutional Neural Network Algorithm

Author(s):  
Kanika Gautam ◽  
Sunil Kumar Jangir ◽  
Manish Kumar ◽  
Jay Sharma

Malaria is a disease caused when a female Anopheles mosquito bites. There are over 200 million cases recorded per year with more than 400,000 deaths. Current methods of diagnosis are effective; however, they work on technologies that do not produce higher accuracy results. Henceforth, to improve the prediction rate of the disease, modern technologies need to be performed for obtain accurate results. Deep learning algorithms are developed to detect, learn, and determine the containing parasites from the red blood smears. This chapter shows the implementation of a deep learning algorithm to identify the malaria parasites with higher accuracy.

2020 ◽  
Author(s):  
Nishtha Srivastava ◽  
Kai Zhou ◽  
Jan Steinheimer ◽  
Johannes Faber ◽  
Horst Stoecker

<p class="western" align="justify"><span>Earthquakes have disastrously impacted communities by destructing the buildings and infrastructure and creating substantial setbacks in the socio-economic development of a region in addition to the huge human loss. They are inevitable and considered extremely difficult to predict. Earthquake prediction research is being carried out for more than 100 years with no well acknowledged model achieved till date. However, the analysis of past seismic stress history of an active fault may help in understanding the stress build up and the local breaking points of the faults. Yet, analysing and interpreting the abundant seismological dataset is most time consuming and is a herculean task.</span></p> <p class="western" align="justify"><span>The possibilities to solve big data, complex problems with Deep Learning are undeniable, however, it’s usage in Seismology is still in its early stage. The implementation of Deep Learning algorithms has the potential to decipher the complex patterns and hidden information in past stress history that is nearly impossible for scientists. The careful implementation of various Deep Learning algorithms in the exponentially growing seismic data can significantly improve the Early Warning System. In the present study, we train a time efficient machine/deep learning algorithm to self-learn and decode the intricate stress accumulation and release pattern, to estimate the probability of local breakdowns of the fault.</span></p> <p class="western" align="justify"><a name="_GoBack"></a> <span>The study region for the present research is Indonesia, which under the influence of the Eurasian, Indo-Australian, Philippine and Pacific plates, immensely suffers due to high seismic activity. The principal contributor in the seismicity of the region is Java-Sunda Trench which lies in the Pacific Ring of Fire (PROF). Owing to the high frequency of earthquakes striking every year from different epicentres, the region provides a huge database. The earthquakes triggering in the region from 1970-2018 is downloaded from the International Seismological Centre website (http://www.isc.ac.uk). These earthquake data comprised of ~270,000 events with the information of Latitude, Longitude, Time of the event and focal depth. To respect the bias which is unavoidable due to the change of the quality of the sensors and the data over the decades, the data is divided into subsets. We considered both small and large magnitude earthquakes along the subduction line to generate a localized time series of stress release to understand the seismic history of the region. By using different neural network models such as one dimensional Convolutional Neural Network (CNN), Recurrent Neural Network (RNN), an optimized Deep Learning algorithm is trained to understand the intricate pattern associated with the seismic stress release in region. This specialized model is expected to empower seismologist by providing a time saving, automated process for the identification of the zone of failures.</span></p>


Cancers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 652 ◽  
Author(s):  
Carlo Augusto Mallio ◽  
Andrea Napolitano ◽  
Gennaro Castiello ◽  
Francesco Maria Giordano ◽  
Pasquale D'Alessio ◽  
...  

Background: Coronavirus disease 2019 (COVID-19) pneumonia and immune checkpoint inhibitor (ICI) therapy-related pneumonitis share common features. The aim of this study was to determine on chest computed tomography (CT) images whether a deep convolutional neural network algorithm is able to solve the challenge of differential diagnosis between COVID-19 pneumonia and ICI therapy-related pneumonitis. Methods: We enrolled three groups: a pneumonia-free group (n = 30), a COVID-19 group (n = 34), and a group of patients with ICI therapy-related pneumonitis (n = 21). Computed tomography images were analyzed with an artificial intelligence (AI) algorithm based on a deep convolutional neural network structure. Statistical analysis included the Mann–Whitney U test (significance threshold at p < 0.05) and the receiver operating characteristic curve (ROC curve). Results: The algorithm showed low specificity in distinguishing COVID-19 from ICI therapy-related pneumonitis (sensitivity 97.1%, specificity 14.3%, area under the curve (AUC) = 0.62). ICI therapy-related pneumonitis was identified by the AI when compared to pneumonia-free controls (sensitivity = 85.7%, specificity 100%, AUC = 0.97). Conclusions: The deep learning algorithm is not able to distinguish between COVID-19 pneumonia and ICI therapy-related pneumonitis. Awareness must be increased among clinicians about imaging similarities between COVID-19 and ICI therapy-related pneumonitis. ICI therapy-related pneumonitis can be applied as a challenge population for cross-validation to test the robustness of AI models used to analyze interstitial pneumonias of variable etiology.


Nowadays researchers are focused on processing the multi-media data for classifying the queries of end users by using search engines. The hybrid combination of a powerful classifier and deep feature extractor are used to develop a robust model, which is performed in a high dimensional space. In this research, a three different types of algorithms are combined to attain a stochastic belief space policy, where these algorithms include generative adversary modelling, maximum entropy Reinforcement Learning (RL) and belief space planning which leads to develop a multi-model classification algorithm. In the simulation framework, different adversarial behaviours are used to minimize the agent's action predictability, which has resulted the proposed method to attain robustness, while comparing with unmodelled adversarial strategies. The proposed reinforcement based Deep Learning (DL) algorithm can be used as multi-model classification purpose. The single neural network algorithm can perform the classification on text data and image data. The RL learns the appropriate belief space policy from the feature extracted information of the text and image data, the belief space policy is generated based on the maximum entropy computation


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Liding Yao ◽  
Xiaojun Guan ◽  
Xiaowei Song ◽  
Yanbin Tan ◽  
Chun Wang ◽  
...  

AbstractRib fracture detection is time-consuming and demanding work for radiologists. This study aimed to introduce a novel rib fracture detection system based on deep learning which can help radiologists to diagnose rib fractures in chest computer tomography (CT) images conveniently and accurately. A total of 1707 patients were included in this study from a single center. We developed a novel rib fracture detection system on chest CT using a three-step algorithm. According to the examination time, 1507, 100 and 100 patients were allocated to the training set, the validation set and the testing set, respectively. Free Response ROC analysis was performed to evaluate the sensitivity and false positivity of the deep learning algorithm. Precision, recall, F1-score, negative predictive value (NPV) and detection and diagnosis were selected as evaluation metrics to compare the diagnostic efficiency of this system with radiologists. The radiologist-only study was used as a benchmark and the radiologist-model collaboration study was evaluated to assess the model’s clinical applicability. A total of 50,170,399 blocks (fracture blocks, 91,574; normal blocks, 50,078,825) were labelled for training. The F1-score of the Rib Fracture Detection System was 0.890 and the precision, recall and NPV values were 0.869, 0.913 and 0.969, respectively. By interacting with this detection system, the F1-score of the junior and the experienced radiologists had improved from 0.796 to 0.925 and 0.889 to 0.970, respectively; the recall scores had increased from 0.693 to 0.920 and 0.853 to 0.972, respectively. On average, the diagnosis time of radiologist assisted with this detection system was reduced by 65.3 s. The constructed Rib Fracture Detection System has a comparable performance with the experienced radiologist and is readily available to automatically detect rib fracture in the clinical setting with high efficacy, which could reduce diagnosis time and radiologists’ workload in the clinical practice.


Author(s):  
Wenjing She

In this research, Dunhuang murals is taken as the object of restoration, and the role of digital repair combined with deep learning algorithm in mural restoration is explored. First, the image restoration technology is described, as well as its advantages and disadvantages are analyzed. Second, the deep learning algorithm based on artificial neural network is described and analyzed. Finally, the deep learning algorithm is integrated into the digital repair technology, and a mural restoration method based on the generalized regression neural network is proposed. The morphological expansion method and anisotropic diffusion method are used to preprocess the image. The MATLAB software is used for the simulation analysis and evaluation of the image restoration effect. The results show that in the restoration of the original image, the accuracy of the digital image restoration technology is not high. The nontexture restoration technology is not applicable in the repair of large-scale texture areas. The predicted value of the mural restoration effect based on the generalized neural network is closer to the true value. The anisotropic diffusion method has a significant effect on the processing of image noise. In the image similarity rate, the different number of training samples and smoothing parameters are compared and analyzed. It is found that when the value of δ is small, the number of training samples should be increased to improve the accuracy of the prediction value. If the number of training samples is small, a larger value of δ is needed to get a better prediction effect, and the best restoration effect is obtained for the restored image. Through this study, it is found that this study has a good effect on the restoration model of Dunhuang murals. It provides experimental reference for the restoration of later murals.


2019 ◽  
Vol 5 (Supplement_1) ◽  
Author(s):  
David Nieuwenhuijse ◽  
Bas Oude Munnink ◽  
My Phan ◽  
Marion Koopmans

Abstract Sewage samples have a high potential benefit for surveillance of circulating pathogens because they are easy to obtain and reflect population-wide circulation of pathogens. These type of samples typically contain a great diversity of viruses. Therefore, one of the main challenges of metagenomic sequencing of sewage for surveillance is sequence annotation and interpretation. Especially for high-threat viruses, false positive signals can trigger unnecessary alerts, but true positives should not be missed. Annotation thus requires high sensitivity and specificity. To better interpret annotated reads for high-threat viruses, we attempt to determine how classifiable they are in a background of reads of closely related low-threat viruses. As an example, we attempted to distinguish poliovirus reads, a virus of high public health importance, from other enterovirus reads. A sequence-based deep learning algorithm was used to classify reads as either polio or non-polio enterovirus. Short reads were generated from 500 polio and 2,000 non-polio enterovirus genomes as a training set. By training the algorithm on this dataset we try to determine, on a single read level, which short reads can reliably be labeled as poliovirus and which cannot. After training the deep learning algorithm on the generated reads we were able to calculate the probability with which a read can be assigned to a poliovirus genome or a non-poliovirus genome. We show that the algorithm succeeds in classifying the reads with high accuracy. The probability of assigning the read to the correct class was related to the location in the genome to which the read mapped, which conformed with our expectations since some regions of the genome are more conserved than others. Classifying short reads of high-threat viral pathogens seems to be a promising application of sequence-based deep learning algorithms. Also, recent developments in software and hardware have facilitated the development and training of deep learning algorithms. Further plans of this work are to characterize the hard-to-classify regions of the poliovirus genome, build larger training databases, and expand on the current approach to other viruses.


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